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midazolam and Brugada Syndrome

midazolam has been researched along with Brugada Syndrome in 2 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Brugada Syndrome: An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Research Excerpts

ExcerptRelevanceReference
"Avoiding propofol in patients with Brugada syndrome has been suggested because of the theoretical risk of provoking ventricular arrhythmias, although propofol may be selected for conscious sedation during electrophysiological procedures in catheterization laboratories."7.88Propofol for implantable cardioverter defibrillator implantation in patients with Brugada syndrome. ( Kim, SH; Kim, WJ; Kwon, HM; Nam, GB; Park, HS; Park, SU; Rhim, JH, 2018)
"Avoiding propofol in patients with Brugada syndrome has been suggested because of the theoretical risk of provoking ventricular arrhythmias, although propofol may be selected for conscious sedation during electrophysiological procedures in catheterization laboratories."3.88Propofol for implantable cardioverter defibrillator implantation in patients with Brugada syndrome. ( Kim, SH; Kim, WJ; Kwon, HM; Nam, GB; Park, HS; Park, SU; Rhim, JH, 2018)
"Brugada syndrome is an inherited arrhythmogenic disease that may cause sudden cardiac death due to ventricular fibrillation in young adults."1.46Brugada-Phenocopy Induced by Propafenone Overdose and Successful Treatment: A Case Report. ( Arı, ME; Ekici, F, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arı, ME1
Ekici, F1
Kwon, HM1
Kim, SH1
Park, SU1
Rhim, JH1
Park, HS1
Kim, WJ1
Nam, GB1

Other Studies

2 other studies available for midazolam and Brugada Syndrome

ArticleYear
Brugada-Phenocopy Induced by Propafenone Overdose and Successful Treatment: A Case Report.
    Balkan medical journal, 2017, Sep-29, Volume: 34, Issue:5

    Topics: Adolescent; Adolescent Behavior; Anticonvulsants; Brugada Syndrome; Chicago; Electrocardiography; El

2017
Propofol for implantable cardioverter defibrillator implantation in patients with Brugada syndrome.
    Pacing and clinical electrophysiology : PACE, 2018, Volume: 41, Issue:6

    Topics: Adjuvants, Anesthesia; Adult; Brugada Syndrome; Conscious Sedation; Defibrillators, Implantable; Fem

2018