midazolam has been researched along with Brain Injuries in 32 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury." | 7.83 | Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. ( Doctor, A; Kharasch, ED; Leonard, JR; Pineda, JA; Wallendorf, MJ; Welch, TP, 2016) |
| "Remifentanil was effective, well tolerated and provided comparable haemodynamic stability to that of the hypnotic-based regimen." | 6.71 | Safety and efficacy of analgesia-based sedation with remifentanil versus standard hypnotic-based regimens in intensive care unit patients with brain injuries: a randomised, controlled trial [ISRCTN50308308]. ( Karabinis, A; Kirkham, AJ; Komnos, A; Mandragos, K; Soukup, J; Speelberg, B; Stergiopoulos, S, 2004) |
| "Seizures were elicited within ∼8 minutes after DFP exposure that progressively developed into persistent SE lasting for hours." | 5.48 | Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. ( Kuruba, R; Reddy, DS; Wu, X, 2018) |
| "To evaluate the clinical effectiveness of bolus-dose fentanyl and midazolam to treat episodic intracranial hypertension in children with severe traumatic brain injury." | 3.83 | Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury. ( Doctor, A; Kharasch, ED; Leonard, JR; Pineda, JA; Wallendorf, MJ; Welch, TP, 2016) |
| " Magnesium sulfate (MGS) is used to suppress eclamptic seizures in pregnant women with hypertension and was shown to block kainate-induced convulsions." | 3.79 | Magnesium sulfate treatment against sarin poisoning: dissociation between overt convulsions and recorded cortical seizure activity. ( Bloch-Shilderman, E; Brandeis, R; Egoz, I; Grauer, E; Katalan, S; Lazar, S; Rabinovitz, I; Raveh, L, 2013) |
| "Remifentanil was effective, well tolerated and provided comparable haemodynamic stability to that of the hypnotic-based regimen." | 2.71 | Safety and efficacy of analgesia-based sedation with remifentanil versus standard hypnotic-based regimens in intensive care unit patients with brain injuries: a randomised, controlled trial [ISRCTN50308308]. ( Karabinis, A; Kirkham, AJ; Komnos, A; Mandragos, K; Soukup, J; Speelberg, B; Stergiopoulos, S, 2004) |
| " During long-term administration of thiopental and midazolam, pathologically elevated ventricular CSF glutamate levels were associated with significantly increased glutamine and alanine levels up to 14 days after trauma." | 2.69 | Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients. ( Kempski, OS; Kossmann, T; Morganti-Kossmann, MC; Pleines, UE; Stocker, R; Stover, JF, 1999) |
| "Ketamine was supposed to be contra-indicated in head injured patients although it possesses numerous advantages over other commonly used analgosedative drugs." | 2.68 | Ketamine for analgosedative therapy in intensive care treatment of head-injured patients. ( Braun, U; Gremmelt, A; Kolenda, H; Markakis, E; Rading, S, 1996) |
| "Midazolam-treated rats had significant neuronal degeneration in limbic structures, mainly at one month postexposure, followed by neuronal loss in the basolateral amygdala and the CA1 hippocampal area." | 1.91 | Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure. ( Apland, JP; Aroniadou-Anderjaska, V; Braga, MF; Figueiredo, TH; Rossetti, K, 2023) |
| "Pretreatment with midazolam reversed H/R-induced apoptosis and downregulation of EAAT2 mRNA and protein expression in the hippocampus." | 1.56 | Midazolam contributes to neuroprotection against hypoxia/reoxygenation-induced brain injury in neonatal rats via regulation of EAAT2. ( Dong, Y; Liu, H; Ma, C; Shan, Y; Sun, S; Tang, Z; Yang, F; Zhang, Y, 2020) |
| "Seizures were elicited within ∼8 minutes after DFP exposure that progressively developed into persistent SE lasting for hours." | 1.48 | Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents. ( Kuruba, R; Reddy, DS; Wu, X, 2018) |
| "Cardiac arrest is a leading cause of death and disability worldwide." | 1.46 | General anesthetics protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in zebrafish. ( Du, JL; Wang, B; Wang, YW; Xu, DJ; Zhao, X; Zheng, Y, 2017) |
| "Midazolam was injected either at 1 min (1 mg/kg, im), or 1 h later (1 or 5 mg/kg i." | 1.42 | Sarin-induced brain damage in rats is attenuated by delayed administration of midazolam. ( Chapman, S; Egoz, I; Gilat, E; Grauer, E; Kadar, T; Rabinovitz, I; Raveh, L; Yaakov, G, 2015) |
| "The propofol infusion rate was non-significantly lower with drainage." | 1.38 | Effect of continuous cerebrospinal fluid drainage on therapeutic intensity in severe traumatic brain injury. ( Boch, AL; Boroli, F; Chauvet, D; Lescot, T; Puybasset, L; Reina, V, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 7 (21.88) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 14 (43.75) | 24.3611 |
| 2020's | 5 (15.63) | 2.80 |
| Authors | Studies |
|---|---|
| Sebastiani, A | 1 |
| Bender, S | 1 |
| Schäfer, MKE | 1 |
| Thal, SC | 1 |
| Ikonomidou, C | 1 |
| Wang, SH | 1 |
| Fuhler, NA | 1 |
| Larson, S | 1 |
| Capuano, S | 1 |
| Brunner, KR | 1 |
| Crosno, K | 1 |
| Simmons, HA | 1 |
| Mejia, AF | 1 |
| Noguchi, KK | 1 |
| Matsuishi, Y | 1 |
| Hoshino, H | 1 |
| Enomoto, Y | 1 |
| Shimojo, N | 1 |
| Matsubara, M | 1 |
| Kato, H | 1 |
| Mathis, BJ | 1 |
| Morita, K | 1 |
| Hiramatsu, Y | 1 |
| Inoue, Y | 1 |
| Figueiredo, TH | 1 |
| Aroniadou-Anderjaska, V | 1 |
| Apland, JP | 1 |
| Rossetti, K | 1 |
| Braga, MF | 1 |
| Tang, Z | 1 |
| Yang, F | 1 |
| Dong, Y | 1 |
| Ma, C | 1 |
| Sun, S | 1 |
| Shan, Y | 1 |
| Zhang, Y | 1 |
| Liu, H | 1 |
| Xu, DJ | 1 |
| Wang, B | 1 |
| Zhao, X | 1 |
| Zheng, Y | 1 |
| Du, JL | 1 |
| Wang, YW | 1 |
| Wu, X | 1 |
| Kuruba, R | 1 |
| Reddy, DS | 1 |
| Sanz-García, A | 1 |
| Pérez-Romero, M | 1 |
| Pastor, J | 1 |
| Sola, RG | 1 |
| Vega-Zelaya, L | 1 |
| Vega, G | 1 |
| Monasterio, F | 1 |
| Torrecilla, C | 1 |
| Pulido, P | 1 |
| Ortega, GJ | 1 |
| Hertle, D | 1 |
| Werhahn, L | 1 |
| Beynon, C | 1 |
| Zweckberger, K | 1 |
| Vienenkötter, B | 1 |
| Jung, CS | 1 |
| Unterberg, A | 1 |
| Kiening, K | 1 |
| Sakowitz, O | 1 |
| Gu, JW | 1 |
| Yang, T | 1 |
| Kuang, YQ | 1 |
| Huang, HD | 1 |
| Kong, B | 1 |
| Shu, HF | 1 |
| Yu, SX | 1 |
| Zhang, JH | 1 |
| Hertle, DN | 1 |
| Santos, E | 1 |
| Hagenston, AM | 1 |
| Jungk, C | 1 |
| Haux, D | 1 |
| Unterberg, AW | 1 |
| Sakowitz, OW | 1 |
| Chapman, S | 1 |
| Yaakov, G | 1 |
| Egoz, I | 2 |
| Rabinovitz, I | 2 |
| Raveh, L | 2 |
| Kadar, T | 1 |
| Gilat, E | 1 |
| Grauer, E | 2 |
| Yen, HC | 1 |
| Chen, TW | 1 |
| Yang, TC | 1 |
| Wei, HJ | 1 |
| Hsu, JC | 1 |
| Lin, CL | 1 |
| Welch, TP | 1 |
| Wallendorf, MJ | 1 |
| Kharasch, ED | 1 |
| Leonard, JR | 1 |
| Doctor, A | 1 |
| Pineda, JA | 1 |
| Mesa Suárez, P | 1 |
| Santotoribio, JD | 1 |
| Ramos Ramos, V | 1 |
| González García, MÁ | 1 |
| Pérez Ramos, S | 1 |
| Portilla Huertas, D | 1 |
| Muñoz Hoyos, A | 1 |
| Oddo, M | 1 |
| Crippa, IA | 1 |
| Mehta, S | 1 |
| Menon, D | 1 |
| Payen, JF | 1 |
| Taccone, FS | 1 |
| Citerio, G | 1 |
| Tanguy, M | 1 |
| Seguin, P | 1 |
| Laviolle, B | 1 |
| Bleichner, JP | 1 |
| Morandi, X | 1 |
| Malledant, Y | 1 |
| Lescot, T | 1 |
| Boroli, F | 1 |
| Reina, V | 1 |
| Chauvet, D | 1 |
| Boch, AL | 1 |
| Puybasset, L | 1 |
| Katalan, S | 1 |
| Lazar, S | 1 |
| Brandeis, R | 1 |
| Bloch-Shilderman, E | 1 |
| Bourgoin, A | 1 |
| Albanèse, J | 1 |
| Wereszczynski, N | 1 |
| Charbit, M | 1 |
| Vialet, R | 1 |
| Martin, C | 1 |
| Fukuoka, N | 1 |
| Aibiki, M | 2 |
| Tsukamoto, T | 1 |
| Seki, K | 1 |
| Morita, S | 1 |
| Baguley, IJ | 1 |
| Cameron, ID | 1 |
| Green, AM | 1 |
| Slewa-Younan, S | 1 |
| Marosszeky, JE | 1 |
| Gurka, JA | 1 |
| Karabinis, A | 1 |
| Mandragos, K | 1 |
| Stergiopoulos, S | 1 |
| Komnos, A | 1 |
| Soukup, J | 1 |
| Speelberg, B | 1 |
| Kirkham, AJ | 1 |
| Schoeffler, P | 1 |
| Haberer, JP | 1 |
| Holzer, J | 1 |
| Bonnard, M | 1 |
| Voitellier, E | 1 |
| McArthur, CJ | 1 |
| Gin, T | 1 |
| McLaren, IM | 1 |
| Critchley, JA | 1 |
| Oh, TE | 1 |
| Fowler, SB | 1 |
| Hertzog, J | 1 |
| Wagner, BK | 1 |
| Stewart, L | 1 |
| Bullock, R | 1 |
| Rafferty, C | 1 |
| Fitch, W | 1 |
| Teasdale, GM | 1 |
| Kolenda, H | 1 |
| Gremmelt, A | 1 |
| Rading, S | 1 |
| Braun, U | 1 |
| Markakis, E | 1 |
| Stover, JF | 1 |
| Pleines, UE | 1 |
| Morganti-Kossmann, MC | 1 |
| Stocker, R | 1 |
| Kempski, OS | 1 |
| Kossmann, T | 1 |
| Maekawa, S | 1 |
| Yokono, S | 1 |
| Wroblewski, BA | 2 |
| Joseph, AB | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Triple-blind Placebo Controlled Trial of Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival and Neurological Outcome[NCT04009759] | Phase 1 | 240 participants (Anticipated) | Interventional | 2021-10-01 | Not yet recruiting | ||
| Clinical Study of the Safety and Efficacy of Analgesia-first Minimal Sedation as an Early Antihypertensive Treatment for Spontaneous Intracerebral Hemorrhage[NCT03207100] | 338 participants (Actual) | Interventional | 2017-12-06 | Completed | |||
| Effect of Ketamine Versus Sufentanil on Cerebral Glutamate After Traumatic Brain Injury : a Randomized, Double-blinded, Microdialysis Study[NCT02232347] | Phase 2 | 20 participants (Anticipated) | Interventional | 2014-10-31 | Not yet recruiting | ||
| Prospective Study of Induction Medications Used in the Rapid Sequence Intubation of Trauma Patients and a Comparison of Effects on Outcomes[NCT04291521] | 7,000 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| the Research of Analgesia and Sedation Effect of Remifentanil on ICU Short Operation[NCT02635802] | Phase 4 | 1,500 participants (Anticipated) | Interventional | 2015-12-31 | Not yet recruiting | ||
| Intranasal Midazolam Versus Rectal Diazepam for the Home Treatment of Seizure Activity in Pediatric Patients With Epilepsy[NCT00326612] | Phase 2 | 358 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Length of seizure. (NCT00326612)
Timeframe: 24 hours
| Intervention | Minutes (Median) |
|---|---|
| Intranasal Midazolam | 3.0 |
| Rectal Diazepam | 4.3 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 21 |
| Rectal Diazepam | 17 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 4 |
| Rectal Diazepam | 3 |
(NCT00326612)
Timeframe: 12 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 1 |
| Rectal Diazepam | 1 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 5 |
| Rectal Diazepam | 5 |
Respiratory depression was defined as intubation at Emergency Department discharge. (NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 1 |
| Rectal Diazepam | 0 |
Respiratory depression was defined as requiring oxygen at discharge from the Emergency Department. (NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 3 |
| Rectal Diazepam | 1 |
3 reviews available for midazolam and Brain Injuries
| Article | Year |
|---|---|
Comparison of the safety and efficacy of propofol with midazolam for sedation of patients with severe traumatic brain injury: a meta-analysis.
Topics: Anesthesia; Brain Injuries; Cerebrovascular Circulation; Conscious Sedation; Drug Monitoring; Female | 2014 |
Optimizing sedation in patients with acute brain injury.
Topics: Analgesia; Brain Injuries; Critical Care; Critical Illness; Deep Sedation; Humans; Hypnotics and Sed | 2016 |
Pharmacological interventions for agitation in head-injured patients in the acute care setting.
Topics: Adult; Brain Injuries; Critical Care; Dose-Response Relationship, Drug; Drug Administration Schedule | 1995 |
11 trials available for midazolam and Brain Injuries
| Article | Year |
|---|---|
Levels of F2-isoprostanes, F4-neuroprostanes, and total nitrate/nitrite in plasma and cerebrospinal fluid of patients with traumatic brain injury.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Biomarkers; Brain Injuries; Chromatography, Gas; | 2015 |
Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury.
Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Cerebral Cortex; Female; Glucose; Glutamic Acid; | 2012 |
Safety of sedation with ketamine in severe head injury patients: comparison with sufentanil.
Topics: Adolescent; Adult; Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Brain Injuries; Cerebr | 2003 |
Safety of sedation with ketamine in severe head injury patients: comparison with sufentanil.
Topics: Adolescent; Adult; Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Brain Injuries; Cerebr | 2003 |
Safety of sedation with ketamine in severe head injury patients: comparison with sufentanil.
Topics: Adolescent; Adult; Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Brain Injuries; Cerebr | 2003 |
Safety of sedation with ketamine in severe head injury patients: comparison with sufentanil.
Topics: Adolescent; Adult; Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Brain Injuries; Cerebr | 2003 |
Biphasic concentration change during continuous midazolam administration in brain-injured patients undergoing therapeutic moderate hypothermia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Biological Availability; Brain Inj | 2004 |
Safety and efficacy of analgesia-based sedation with remifentanil versus standard hypnotic-based regimens in intensive care unit patients with brain injuries: a randomised, controlled trial [ISRCTN50308308].
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Analgesics, Opioid; Brain Injuries; Drug Monitoring; | 2004 |
[Comparative hemodynamic effects of midazolam and flunitrazepam in head injury patients under controlled ventilation].
Topics: Adult; Benzodiazepines; Brain Injuries; Female; Flunitrazepam; Hemodynamics; Humans; Male; Midazolam | 1984 |
Gastric emptying following brain injury: effects of choice of sedation and intracranial pressure.
Topics: Acetaminophen; Adult; Brain Injuries; Conscious Sedation; Drug Therapy, Combination; Female; Gastric | 1995 |
Propofol sedation in severe head injury fails to control high ICP, but reduces brain metabolism.
Topics: Adolescent; Adult; Brain; Brain Edema; Brain Injuries; Child; Conscious Sedation; Energy Metabolism; | 1994 |
Ketamine for analgosedative therapy in intensive care treatment of head-injured patients.
Topics: Adolescent; Adult; Aged; Blood Pressure; Brain Injuries; Conscious Sedation; Critical Care; Dose-Res | 1996 |
Thiopental and midazolam do not seem to impede metabolism of glutamate in brain-injured patients.
Topics: Adolescent; Adult; Aged; Alanine; Brain Injuries; Cerebral Ventricles; Glutamic Acid; Glutamine; Hum | 1999 |
Moderate hypothermia improves imbalances of thromboxane A2 and prostaglandin I2 production after traumatic brain injury in humans.
Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Analgesics, Opioid; Arachidonic Acid; Brain I | 2000 |
18 other studies available for midazolam and Brain Injuries
| Article | Year |
|---|---|
Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury.
Topics: Animals; Benzodiazepines; Brain; Brain Injuries; Brain Injuries, Traumatic; Flumazenil; Humans; Mice | 2022 |
Mild hypothermia fails to protect infant macaques from brain injury caused by prolonged exposure to Antiseizure drugs.
Topics: Animals; Brain; Brain Injuries; Humans; Hypothermia; Hypothermia, Induced; Infant; Infant, Newborn; | 2022 |
Pediatric delirium is associated with increased brain injury marker levels in cardiac surgery patients.
Topics: Adult; Bayes Theorem; Biomarkers; Brain Injuries; Cardiac Surgical Procedures; Child; Coma; Delirium | 2022 |
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure.
Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Female; Male; Midazolam; Nerve Agents; Rats; Seizur | 2023 |
Midazolam contributes to neuroprotection against hypoxia/reoxygenation-induced brain injury in neonatal rats via regulation of EAAT2.
Topics: Animals; Animals, Newborn; Brain Injuries; Dose-Response Relationship, Drug; Excitatory Amino Acid T | 2020 |
General anesthetics protects against cardiac arrest-induced brain injury by inhibiting calcium wave propagation in zebrafish.
Topics: Anesthetics, General; Animals; Apoptosis; Brain; Brain Injuries; Calcium Signaling; Heart Arrest; Ke | 2017 |
Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents.
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Brain Injuries; Cholinesterase Inhibitors; Drug Re | 2018 |
Potential EEG biomarkers of sedation doses in intensive care patients unveiled by using a machine learning approach.
Topics: Adult; Brain Injuries; Cohort Studies; Critical Care; Dose-Response Relationship, Drug; Electroencep | 2019 |
Depression of neuronal activity by sedatives is associated with adverse effects after brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Disease Models, Animal; Electroencephalography; Hypno | 2013 |
Cerebral Glucose Metabolism and Sedation in Brain-injured Patients: A Microdialysis Study.
Topics: Adult; Aged; Brain; Brain Injuries; Dose-Response Relationship, Drug; Female; Glucose; Glutamic Acid | 2015 |
Sarin-induced brain damage in rats is attenuated by delayed administration of midazolam.
Topics: Analysis of Variance; Animals; Brain Injuries; Carrier Proteins; Cholinesterase Inhibitors; Cytokine | 2015 |
Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury.
Topics: Adolescent; Brain Injuries; Cerebrovascular Circulation; Child; Child, Preschool; Drug Administratio | 2016 |
[Brain damage after general anesthesia].
Topics: Adolescent; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; Brai | 2016 |
Effect of continuous cerebrospinal fluid drainage on therapeutic intensity in severe traumatic brain injury.
Topics: Adolescent; Adult; Aged; Blood Gas Analysis; Brain Injuries; Central Nervous System Infections; Cere | 2012 |
Magnesium sulfate treatment against sarin poisoning: dissociation between overt convulsions and recorded cortical seizure activity.
Topics: Animals; Anticonvulsants; Antidotes; Brain Injuries; Cerebral Cortex; Chemical Warfare Agents; Cyclo | 2013 |
Pharmacological management of Dysautonomia following traumatic brain injury.
Topics: Adult; Autonomic Nervous System Diseases; Brain Injuries; Case-Control Studies; Chlorpromazine; Fema | 2004 |
The use of intramuscular midazolam for acute seizure cessation or behavioral emergencies in patients with traumatic brain injury.
Topics: Adult; Brain Injuries; Child; Emergencies; Female; Humans; Injections, Intramuscular; Male; Mental D | 1992 |
Intramuscular midazolam for treatment of acute seizures or behavioral episodes in patients with brain injuries.
Topics: Adult; Aggression; Brain Injuries; Epilepsy, Post-Traumatic; Humans; Injections, Intramuscular; Male | 1992 |