midazolam has been researched along with Brain Diseases in 14 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have previously demonstrated a major inflammatory response with subsequent brain damage which was correlated with the duration of the sarin-induced seizures (Chapman et al." | 7.91 | Time dependent dual effect of anti-inflammatory treatments on sarin-induced brain inflammation: Suggested role of prostaglandins. ( Chapman, S; Egoz, I; Gez, R; Grauer, E; Lazar, S, 2019) |
| " We have previously demonstrated a major inflammatory response with subsequent brain damage which was correlated with the duration of the sarin-induced seizures (Chapman et al." | 3.91 | Time dependent dual effect of anti-inflammatory treatments on sarin-induced brain inflammation: Suggested role of prostaglandins. ( Chapman, S; Egoz, I; Gez, R; Grauer, E; Lazar, S, 2019) |
| " A lower dosage of each substance is necessary to maintain a better state of analgosedation." | 2.67 | [Analgesia and sedation in neurosurgical intensive care patients]. ( Brandt, L; el Gindi, M; Hundt, F, 1990) |
| "To determine the prognostic factors for encephalopathy with bright tree appearance (BTA) in the acute phase through retrospective case evaluation." | 1.42 | Prognostic factors for acute encephalopathy with bright tree appearance. ( Azuma, J; Iwatani, Y; Kagitani-Shimono, K; Kitai, Y; Nabatame, S; Nagai, T; Nakano, S; Okinaga, T; Ozono, K; Tominaga, K; Yamamoto, T, 2015) |
| "Propofol has been shown to protect against neuronal damage induced by brain ischaemia in small animal models." | 1.33 | A moderate dose of propofol and rapidly induced mild hypothermia with extracorporeal lung and heart assist (ECLHA) improve the neurological outcome after prolonged cardiac arrest in dogs. ( Ichinose, K; Okamoto, T; Sugita, M; Taguchi, H; Takeya, M; Tanimoto, H; Tashiro, M; Terasaki, H, 2006) |
| "In flurothyl-treated rats, there were significant reductions in SNPR neuropathologic grade (P = 0." | 1.29 | Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats. ( Garman, RH; Graybeal, JM; Hawkins, RA; Housman, C; Kofke, WA; Towfighi, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Supasai, S | 1 |
| González, EA | 1 |
| Rowland, DJ | 1 |
| Hobson, B | 1 |
| Bruun, DA | 1 |
| Guignet, MA | 1 |
| Soares, S | 1 |
| Singh, V | 1 |
| Wulff, H | 1 |
| Saito, N | 1 |
| Harvey, DJ | 1 |
| Lein, PJ | 1 |
| Zombori, L | 1 |
| Bacon, M | 1 |
| Wood, H | 1 |
| Chatterjee, F | 1 |
| Venkateswaran, R | 1 |
| Lampariello, S | 1 |
| Yoong, M | 1 |
| Chapman, S | 1 |
| Grauer, E | 1 |
| Gez, R | 1 |
| Egoz, I | 1 |
| Lazar, S | 1 |
| Belze, O | 1 |
| Remérand, F | 1 |
| Pujol, A | 1 |
| Fusciardi, J | 1 |
| Azuma, J | 1 |
| Nabatame, S | 1 |
| Nakano, S | 1 |
| Iwatani, Y | 1 |
| Kitai, Y | 1 |
| Tominaga, K | 1 |
| Kagitani-Shimono, K | 1 |
| Okinaga, T | 1 |
| Yamamoto, T | 1 |
| Nagai, T | 1 |
| Ozono, K | 1 |
| Fukuda, S | 1 |
| Kishi, K | 1 |
| Yasuda, K | 1 |
| Sejima, H | 1 |
| Yamaguchi, S | 1 |
| Rosman, Y | 1 |
| Eisenkraft, A | 1 |
| Krivoy, A | 1 |
| Schein, O | 1 |
| Makarovski, I | 1 |
| Shrot, S | 1 |
| Ramaty, E | 1 |
| Shilderman, EB | 1 |
| Kapon, J | 1 |
| Gilat, E | 1 |
| Kadar, T | 1 |
| Maier, S | 1 |
| Daniels, D | 1 |
| Shneor, R | 1 |
| Salomon, S | 1 |
| Tamar, G | 1 |
| Last, D | 1 |
| Mardor, Y | 1 |
| Chu, YC | 1 |
| Tsai, SK | 1 |
| Chan, KH | 1 |
| Kao, SC | 1 |
| Liang, CH | 1 |
| Lin, SM | 1 |
| Khan, RB | 1 |
| Schmidt, JE | 1 |
| Tamburro, RF | 1 |
| Ichinose, K | 1 |
| Okamoto, T | 1 |
| Tanimoto, H | 1 |
| Taguchi, H | 1 |
| Tashiro, M | 1 |
| Sugita, M | 1 |
| Takeya, M | 1 |
| Terasaki, H | 1 |
| Kofke, WA | 2 |
| Towfighi, J | 1 |
| Garman, RH | 2 |
| Graybeal, JM | 1 |
| Housman, C | 1 |
| Hawkins, RA | 1 |
| Sinz, EH | 1 |
| Hundt, F | 1 |
| el Gindi, M | 1 |
| Brandt, L | 1 |
| Chiolero, RL | 1 |
| Ravussin, PA | 1 |
| Freeman, J | 1 |
1 trial available for midazolam and Brain Diseases
| Article | Year |
|---|---|
[Analgesia and sedation in neurosurgical intensive care patients].
Topics: Alfentanil; Arousal; Brain Diseases; Cerebrovascular Circulation; Critical Care; Drug Administration | 1990 |
13 other studies available for midazolam and Brain Diseases
| Article | Year |
|---|---|
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
Topics: Animals; Brain Diseases; Cholinesterase Inhibitors; Diazepam; GABA Modulators; Gliosis; Isoflurophat | 2020 |
Severe cortical damage associated with COVID-19 case report.
Topics: Acute Kidney Injury; Adolescent; Airway Extubation; Anticonvulsants; Blood Coagulation Disorders; Bo | 2021 |
Time dependent dual effect of anti-inflammatory treatments on sarin-induced brain inflammation: Suggested role of prostaglandins.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Atropine; Brain Diseases; Chemical Warfare Agent | 2019 |
Hyperammonaemic encephalopathy and a flat electroencephalogram caused by valproic acid.
Topics: Adult; Anesthesia, General; Anticonvulsants; Brain Diseases; Craniocerebral Trauma; Electroencephalo | 2013 |
Prognostic factors for acute encephalopathy with bright tree appearance.
Topics: Acute Disease; Anti-Anxiety Agents; Brain; Brain Diseases; Child; Child, Preschool; Creatinine; Diaz | 2015 |
Rotavirus-associated encephalopathy with a reversible splenial lesion.
Topics: Brain Diseases; Child, Preschool; Consciousness Disorders; Corpus Callosum; Diffusion Magnetic Reson | 2009 |
Using MRI for the assessment of paraoxon-induced brain damage and efficacy of antidotal treatment.
Topics: Animals; Antidotes; Atropine; Brain; Brain Diseases; Cholinergic Antagonists; Cholinesterase Inhibit | 2012 |
Lateral medullary syndrome after prone position for general surgery.
Topics: Adult; Brain Diseases; Cerebral Arteries; Functional Laterality; GABA Modulators; Humans; Magnetic R | 2002 |
A reversible generalized movement disorder in critically ill children with cancer.
Topics: Brain Diseases; Brain Neoplasms; Child; Child, Preschool; Critical Illness; Dystonic Disorders; Fema | 2005 |
A moderate dose of propofol and rapidly induced mild hypothermia with extracorporeal lung and heart assist (ECLHA) improve the neurological outcome after prolonged cardiac arrest in dogs.
Topics: Anesthetics, Intravenous; Animals; Brain Diseases; Dogs; Female; Heart Arrest; Heart-Assist Devices; | 2006 |
Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats.
Topics: 3-Mercaptopropionic Acid; Administration, Inhalation; Anesthetics; Animals; Brain Diseases; Flurothy | 1993 |
Phenytoin, midazolam, and naloxone protect against fentanyl-induced brain damage in rats.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Blood Gas Analysis; Body Weight; Brain Diseases; Elect | 2000 |
[Use of flumazenil (RO 15-1788) after prolonged infusion of midazolam in anesthesia for intracranial surgery].
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Brain Diseases; Female; Flumazenil | 1988 |