Page last updated: 2024-10-31

midazolam and Blood Diseases

midazolam has been researched along with Blood Diseases in 3 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"Midazolam and ketamine were administered consecutively by intravenous route under cardiorespiratory monitoring for painful procedures of pediatric hematology."3.81The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology. ( Çakmak, E; Demirsoy, U; Gelen, SA; Sarper, N; Zengin, E, 2015)
" Dosing of major CYP3A substrate drugs needs to be reduced in palliative patients with haematological diseases, otherwise escalation of debilitating symptoms due to drug interactions might occur."2.90Decreased Cytochrome P450 3A activity in palliative patients with haematological diseases: Potential impact on supportive drug therapies. ( Bardenheuer, H; Burhenne, J; Egerer, G; Geist, MJP; Mikus, G; Siller, N, 2019)
" Procedure and recovery time were correlated to ketamine dosage (p <."1.32Sedation with midazolam and ketamine for invasive procedures in children with malignancies and hematological disorders: a prospective study with reference to the sympathomimetic properties of ketamine. ( Aliani, S; Gottschling, S; Graf, N; Meyer, S; Reinhard, H, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Geist, MJP1
Siller, N1
Egerer, G1
Bardenheuer, H1
Burhenne, J1
Mikus, G1
Gelen, SA1
Sarper, N1
Demirsoy, U1
Zengin, E1
Çakmak, E1
Meyer, S1
Aliani, S1
Graf, N1
Reinhard, H1
Gottschling, S1

Trials

1 trial available for midazolam and Blood Diseases

ArticleYear
Decreased Cytochrome P450 3A activity in palliative patients with haematological diseases: Potential impact on supportive drug therapies.
    Basic & clinical pharmacology & toxicology, 2019, Volume: 125, Issue:2

    Topics: Administration, Oral; Adult; Aged; Area Under Curve; Biological Variation, Population; Case-Control

2019

Other Studies

2 other studies available for midazolam and Blood Diseases

ArticleYear
The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:4

    Topics: Adolescent; Analgesia; Analgesics; Bone Marrow Examination; Child; Child, Preschool; Deep Sedation;

2015
Sedation with midazolam and ketamine for invasive procedures in children with malignancies and hematological disorders: a prospective study with reference to the sympathomimetic properties of ketamine.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:4

    Topics: Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Conscious Sedatio

2003