midazolam has been researched along with Autism Spectrum Disorder in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "While midazolam is commonly used as premedication for uncooperative patients, its effects are difficult to predict in patients with autism spectrum disorder for whom abnormalities in gamma-aminobutyric acid have been reported." | 8.31 | Effect of midazolam in autism spectrum disorder: A retrospective observational analysis. ( Hanamoto, H; Hirose, Y; Niwa, H; Oyamaguchi, A; Toyama, M; Yokoe, C, 2023) |
| "Ketamine was most commonly given intravenously (71." | 1.51 | Procedural sedation in children with autism spectrum disorders in the emergency department. ( Brown, JJ; Farooqi, A; Gray, JM; Kannikeswaran, N; Roback, MG; Sethuraman, U, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kenneally, A | 1 |
| Cummins, M | 1 |
| Bailey, A | 1 |
| Yackey, K | 1 |
| Jones, L | 1 |
| Carter, C | 1 |
| Dugan, A | 1 |
| Baum, RA | 1 |
| Hanamoto, H | 1 |
| Hirose, Y | 1 |
| Toyama, M | 1 |
| Yokoe, C | 1 |
| Oyamaguchi, A | 1 |
| Niwa, H | 1 |
| Brown, JJ | 1 |
| Gray, JM | 1 |
| Roback, MG | 1 |
| Sethuraman, U | 1 |
| Farooqi, A | 1 |
| Kannikeswaran, N | 1 |
3 other studies available for midazolam and Autism Spectrum Disorder
| Article | Year |
|---|---|
Intranasal Dexmedetomidine Use in Pediatric Patients for Anxiolysis in the Emergency Department.
Topics: Autism Spectrum Disorder; Child; Dexmedetomidine; Emergency Service, Hospital; Humans; Hypnotics and | 2023 |
Effect of midazolam in autism spectrum disorder: A retrospective observational analysis.
Topics: Anesthesia, General; Autism Spectrum Disorder; Humans; Midazolam; Premedication; Retrospective Studi | 2023 |
Procedural sedation in children with autism spectrum disorders in the emergency department.
Topics: Administration, Intranasal; Administration, Intravenous; Adolescent; Autism Spectrum Disorder; Child | 2019 |