midazolam and Ataxia
midazolam has been researched along with Ataxia in 4 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, midazolam-induced ataxia was significantly modified 3-1/2 h following both restraint and FG 7142 exposure." | 1.30 | FG 7142- and restraint-induced alterations in the ataxic effects of alcohol and midazolam in rats are time dependent. ( Austin, M; Brown, PL; Drugan, RC; Mammola, B; Myles, V, 1999) |
| "Recovery to walking without incoordination was also rapid (< 2 h) and no abnormal behavioural patterns were observed during recovery." | 1.29 | The effect of intravenous administration of variable-dose midazolam after fixed-dose ketamine in healthy awake cats. ( Farver, TB; Ilkiw, JE; McNeal, D; Steffey, EP; Suter, CM, 1996) |
| "Clonazepam did not produce anaesthesia, at doses up to 1 g kg-1 or when given with nitrendipine." | 1.28 | Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644. ( Dolin, SJ; Little, HJ; Patch, TL; Rabbani, M; Taberner, PV, 1991) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ilkiw, JE | 2 |
| Suter, CM | 2 |
| Farver, TB | 2 |
| McNeal, D | 2 |
| Steffey, EP | 2 |
| Austin, M | 1 |
| Myles, V | 1 |
| Brown, PL | 1 |
| Mammola, B | 1 |
| Drugan, RC | 1 |
| Dolin, SJ | 1 |
| Patch, TL | 1 |
| Rabbani, M | 1 |
| Taberner, PV | 1 |
| Little, HJ | 1 |
Other Studies
4 other studies available for midazolam and Ataxia
| Article | Year |
|---|---|
The behaviour of healthy awake cats following intravenous and intramuscular administration of midazolam.
Topics: Animals; Anti-Anxiety Agents; Ataxia; Behavior, Animal; Cats; Chi-Square Distribution; Eating; Femal | 1996 |
The effect of intravenous administration of variable-dose midazolam after fixed-dose ketamine in healthy awake cats.
Topics: Anesthetics, Dissociative; Animals; Anti-Anxiety Agents; Ataxia; Behavior, Animal; Cats; Chi-Square | 1996 |
FG 7142- and restraint-induced alterations in the ataxic effects of alcohol and midazolam in rats are time dependent.
Topics: Animals; Ataxia; Carbolines; Ethanol; GABA Antagonists; GABA Modulators; Male; Midazolam; Motor Acti | 1999 |
Differential interactions between benzodiazepines and the dihydropyridines, nitrendipine and Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |