midazolam and Asthma
midazolam has been researched along with Asthma in 7 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty patients aged 18-75 yr taking bronchodilators chronically for asthma were anesthetized with midazolam, fentanyl, nitrous oxide, and isoflurane; the trachea was intubated without paralysis." | 9.08 | Atracurium versus vecuronium in asthmatic patients. A blinded, randomized comparison of adverse events. ( Caldwell, JE; Fisher, DM; Lau, M, 1995) |
| "We present the case of a young female with a history of allergies to medicines, specifically to benzodiazepines, who presented bronchospasm and oxygen saturation drop after receiving a dose of midazolam into her eye while she was working." | 8.12 | [Ketamine as a treatment of bronchospasm due to an anaphylaxis. A case report]. ( Ávila-García, JE; Calleja-Alarcón, S; Guerrero-Escobar, JC; Romero-Gutiérrez, L; Sánchez-Hurtado, LA, 2022) |
| "Sixty patients aged 18-75 yr taking bronchodilators chronically for asthma were anesthetized with midazolam, fentanyl, nitrous oxide, and isoflurane; the trachea was intubated without paralysis." | 5.08 | Atracurium versus vecuronium in asthmatic patients. A blinded, randomized comparison of adverse events. ( Caldwell, JE; Fisher, DM; Lau, M, 1995) |
| "Propofol, a new intravenous sedative agent, was investigated in 41 asthmatic patients undergoing day-case (outpatient) fiberoptic bronchoscopy." | 5.07 | A comparative evaluation of propofol and midazolam as sedative agents in fiberoptic bronchoscopy. ( Burke, CM; Clarkson, K; O'Connell, F; Pathmakanthan, S; Power, CK, 1993) |
| "We present the case of a young female with a history of allergies to medicines, specifically to benzodiazepines, who presented bronchospasm and oxygen saturation drop after receiving a dose of midazolam into her eye while she was working." | 4.12 | [Ketamine as a treatment of bronchospasm due to an anaphylaxis. A case report]. ( Ávila-García, JE; Calleja-Alarcón, S; Guerrero-Escobar, JC; Romero-Gutiérrez, L; Sánchez-Hurtado, LA, 2022) |
| "Conditions precipitating acute respiratory failure (ARF) were classified into two groups: type 1 (38 episodes) and type 2 (78 episodes)." | 1.35 | Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. ( Concha, A; Díaz, JJ; Los Arcos, M; Mayordomo-Colunga, J; Medina, A; Menéndez, S; Rey, C, 2009) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Calleja-Alarcón, S | 1 |
| Sánchez-Hurtado, LA | 1 |
| Romero-Gutiérrez, L | 1 |
| Guerrero-Escobar, JC | 1 |
| Ávila-García, JE | 1 |
| Mayordomo-Colunga, J | 1 |
| Medina, A | 1 |
| Rey, C | 1 |
| Díaz, JJ | 1 |
| Concha, A | 1 |
| Los Arcos, M | 1 |
| Menéndez, S | 1 |
| Awab, A | 1 |
| Alilou, M | 1 |
| El Moussaoui, R | 1 |
| El Hijri, A | 1 |
| Azzouzi, A | 1 |
| Caldwell, JE | 1 |
| Lau, M | 1 |
| Fisher, DM | 1 |
| Clarkson, K | 1 |
| Power, CK | 1 |
| O'Connell, F | 1 |
| Pathmakanthan, S | 1 |
| Burke, CM | 1 |
| Achar, MN | 1 |
| Achar, KN | 1 |
| Yakel, DL | 1 |
| Whittaker, SE | 1 |
| Elstad, MR | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy and Safety of Gastric Feeding in Critically Ill Pediatric Patients Receiving Non-invasive Positive Pressure Ventilation: A Pilot Study[NCT01301352] | 30 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
| [NCT00440960] | Phase 4 | 0 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trials
2 trials available for midazolam and Asthma
| Article | Year |
|---|---|
Atracurium versus vecuronium in asthmatic patients. A blinded, randomized comparison of adverse events.
Topics: Adult; Aged; Anesthesia, General; Asthma; Atracurium; Female; Fentanyl; Hemodynamics; Humans; Male; | 1995 |
A comparative evaluation of propofol and midazolam as sedative agents in fiberoptic bronchoscopy.
Topics: Ambulatory Care; Asthma; Bronchoscopy; Dose-Response Relationship, Drug; Fiber Optic Technology; Hum | 1993 |
Other Studies
5 other studies available for midazolam and Asthma
| Article | Year |
|---|---|
[Ketamine as a treatment of bronchospasm due to an anaphylaxis. A case report].
Topics: Anaphylaxis; Asthma; Bronchial Spasm; Female; Humans; Ketamine; Midazolam | 2022 |
Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study.
Topics: Adolescent; Anti-Anxiety Agents; Anxiety; Asthma; Bronchiolitis; Child; Child, Preschool; Critical I | 2009 |
[Rhabdomyolysis in severe acute asthma].
Topics: Acidosis; Acute Disease; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Combined Modal | 2009 |
Efficacy of ketamine infusion in refractory asthma complicated by acute myocardial infarction.
Topics: Asthma; Bronchial Spasm; Conscious Sedation; Female; Humans; Infusions, Intravenous; Ketamine; Midaz | 1993 |
Midazolam-induced angioedema and bronchoconstriction.
Topics: Adult; Angioedema; Asthma; Bronchoconstriction; Drug Hypersensitivity; Female; Humans; Midazolam | 1992 |