midazolam has been researched along with Aseptic Necrosis of Femur Head in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam clearance was significantly increased and decreased, compared with baseline in groups P and I respectively (p < 0." | 1.35 | Increased hepatic cytochrome P4503A activity decreases the risk of developing steroid-induced osteonecrosis in a rabbit model. ( Iwaki, H; Iwakiri, K; Kaneshiro, Y; Masada, T; Oda, Y; Ohashi, H; Takaoka, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaneshiro, Y | 2 |
| Takaoka, K | 2 |
| Masada, T | 1 |
| Iwakiri, K | 1 |
| Oda, Y | 1 |
| Iwaki, H | 1 |
| Ohashi, H | 1 |
| Nafziger, AN | 1 |
| Bertino, JS | 1 |
3 other studies available for midazolam and Aseptic Necrosis of Femur Head
| Article | Year |
|---|---|
[Hepatic CYP3A activity in association with development of osteonecrosis of the femoral head].
Topics: Adrenal Cortex Hormones; Adult; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Femu | 2007 |
Increased hepatic cytochrome P4503A activity decreases the risk of developing steroid-induced osteonecrosis in a rabbit model.
Topics: Anesthetics, Intravenous; Animals; Antifungal Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A | 2008 |
Low hepatic cytochrome P450 3A activity is a risk for corticosteroid-induced osteonecrosis.
Topics: Adrenal Cortex Hormones; Biomarkers; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enz | 2007 |