midazolam has been researched along with Apnea, Sleep in 12 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No marked adverse reactions were found in any area for any group." | 6.67 | Clinical safety of flurazepam and midazolam during 14-day use in chronic insomniacs. ( Hauri, P; Kripke, D; Roehrs, T; Sateia, MJ, 1990) |
| " The purpose during sleep, which usually was induced by low-dose midazolam intravenously, was to reveal the site and form of obstruction in obstructive sleep apnea patients and the site of snoring in habitual snorers." | 3.69 | Videoradiography of patients with habitual snoring and/or sleep apnea. Technical description and presentation of videoradiographic results during sleep concerning occurrence of apnea, type of apnea, and site of obstruction. ( Hillarp, B; Nylander, G; Rosén, I; Wickström, O, 1996) |
| " No marked adverse reactions were found in any area for any group." | 2.67 | Clinical safety of flurazepam and midazolam during 14-day use in chronic insomniacs. ( Hauri, P; Kripke, D; Roehrs, T; Sateia, MJ, 1990) |
| "MSA can be accompanied by stridor caused by laryngeal stenosis secondary to vocal cord dysfunction." | 1.56 | Isolated stridor without any other sleeping breathing disorder diagnosed using drug-induced sleep endoscopy in a patient with multiple system atrophy: A case report. ( Heo, SJ; Kim, JS; Lee, BJ; Park, D, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Heo, SJ | 1 |
| Kim, JS | 1 |
| Lee, BJ | 1 |
| Park, D | 1 |
| Van de Perck, E | 1 |
| Vroegop, AV | 2 |
| Op de Beeck, S | 1 |
| Dieltjens, M | 1 |
| Verbruggen, AE | 1 |
| Van de Heyning, PH | 2 |
| Braem, MJ | 2 |
| Vanderveken, OM | 2 |
| Boudewyns, AN | 1 |
| Scholman, J | 1 |
| Saldien, V | 1 |
| Wouters, K | 1 |
| Hamans, E | 1 |
| Dedhia, RC | 1 |
| Weaver, EM | 1 |
| Ayuse, T | 1 |
| Hoshino, Y | 1 |
| Inazawa, T | 1 |
| Oi, K | 1 |
| Schneider, H | 1 |
| Schwartz, AR | 1 |
| Dureuil, B | 2 |
| Gentil, B | 1 |
| Tehindrazanarivelo, A | 1 |
| Lienhart, A | 1 |
| Meyer, B | 1 |
| Fleury, B | 1 |
| Hillarp, B | 1 |
| Nylander, G | 1 |
| Rosén, I | 1 |
| Wickström, O | 1 |
| Dhonneur, G | 1 |
| Combes, X | 1 |
| Leroux, B | 1 |
| Duvaldestin, P | 1 |
| Montravers, P | 1 |
| Desmonts, JM | 1 |
| Sateia, MJ | 1 |
| Hauri, P | 1 |
| Kripke, D | 1 |
| Roehrs, T | 1 |
| Bezel, R | 1 |
| Russi, E | 1 |
| Kronauer, H | 1 |
| Mothersill, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TAP) Block in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study[NCT01075087] | 19 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 Hour total opioid consumption translated into IV morphine equivalents. (NCT01075087)
Timeframe: 24 hours
| Intervention | miligram IV morphine equivalents (Median) |
|---|---|
| Placebo | 13 |
| Active Comparator | 7.5 |
Quality of Recovery 40 Score at 24 hours postoperative. (NCT01075087)
Timeframe: 24 hours post operatively
| Intervention | units on scale 40 (low) - 200 (high) (Median) |
|---|---|
| Placebo | 170 |
| Active Comparator | 175.5 |
3 trials available for midazolam and Apnea, Sleep
| Article | Year |
|---|---|
Postoperative obstructive apnea.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Diaphragm; Electromyography; Flumazenil; GABA | 1999 |
Effects of i.v. midazolam on upper airway resistance.
Topics: Adult; Airway Resistance; Esophagus; Glottis; Humans; Male; Midazolam; Pressure; Random Allocation; | 1992 |
Clinical safety of flurazepam and midazolam during 14-day use in chronic insomniacs.
Topics: Adult; Double-Blind Method; Female; Flurazepam; Humans; Male; Midazolam; Middle Aged; Sleep Apnea Sy | 1990 |
9 other studies available for midazolam and Apnea, Sleep
| Article | Year |
|---|---|
Isolated stridor without any other sleeping breathing disorder diagnosed using drug-induced sleep endoscopy in a patient with multiple system atrophy: A case report.
Topics: Endoscopy; Female; Humans; Hypnotics and Sedatives; Midazolam; Middle Aged; Multiple System Atrophy; | 2020 |
Awake endoscopic assessment of the upper airway during tidal breathing: Definition of anatomical features and comparison with drug-induced sleep endoscopy.
Topics: Adult; Endoscopy; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Propofol; R | 2021 |
Drug-induced sleep endoscopy in sleep-disordered breathing: report on 1,249 cases.
Topics: Adult; Age Factors; Airway Obstruction; Anthropometry; Body Mass Index; Clinical Competence; Cohort | 2014 |
Association between Drug-Induced Sleep Endoscopy and Measures of Sleep Apnea Burden.
Topics: Adult; Anesthetics, Intravenous; Body Mass Index; Endoscopy; Female; Humans; Male; Midazolam; Middle | 2015 |
A pilot study of quantitative assessment of mandible advancement using pressure-flow relationship during midazolam sedation.
Topics: Adult; Continuous Positive Airway Pressure; Dental Occlusion, Centric; Humans; Hypnotics and Sedativ | 2006 |
[Respiratory disease and midazolam].
Topics: Humans; Lung Diseases, Obstructive; Midazolam; Respiration; Sleep Apnea Syndromes | 1995 |
[Respiratory effects of midazolam in patients with obstructive sleep apnea syndromes].
Topics: Adult; Airway Obstruction; Female; Humans; Male; Midazolam; Middle Aged; Oxygen; Polysomnography; Re | 1994 |
Videoradiography of patients with habitual snoring and/or sleep apnea. Technical description and presentation of videoradiographic results during sleep concerning occurrence of apnea, type of apnea, and site of obstruction.
Topics: Barium Sulfate; Contrast Media; Female; Humans; Male; Midazolam; Middle Aged; Pharynx; Polysomnograp | 1996 |
[Life-threatening apnea after midazolam administration in a patient with obstructive sleep apnea syndrome].
Topics: Adult; Airway Obstruction; Airway Resistance; Humans; Lung Volume Measurements; Male; Midazolam; Pos | 1987 |