midazolam has been researched along with Apnea, Obstructive Sleep in 28 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capnography enables the measurement of end-tidal CO2 and thereby the early detection of apnea, prompting immediate intervention to restore ventilation." | 5.19 | Capnographic monitoring of propofol-based sedation during colonoscopy. ( Albert, J; Bojunga, J; Filmann, N; Friedrich-Rust, M; Herrmann, E; Kannengiesser, M; Meckbach, Y; Schroeter, H; Trojan, J; Welte, C; Welte, M; Zeuzem, S, 2014) |
| "This was a retrospective anesthesia chart review of 15 consecutive patients undergoing midazolam/fentanyl intravenous sedation for office-based LAUP treatment for snoring and/or mild obstructive sleep apnea." | 3.73 | Hemodynamics and oxygen saturation during intravenous sedation for office-based laser-assisted uvuloplasty. ( Cillo, JE; Finn, R, 2005) |
| "A 57-year-old male with a documented history of obstructive sleep apnea with loud snoring received deep intravenous sedation with midazolam, fentanyl, ketamine, and propofol infusion and a left interscalene brachial plexus nerve block for a left biceps tendon repair." | 3.73 | Uvular edema secondary to snoring under deep sedation. ( Gerhardt, MA; Miller, RJ, 2006) |
| "Most patients of OSAHS have several stricture levels of upper airway under Midazolam- induced sleep." | 2.73 | [The value of video laryngoscope in localization diagnosis of upper airway stricture in obstructive sleep apnea-hypopnea syndrome during drug-induced sleep]. ( Cao, J; Chao, J; Jiang, T; Shi, L; Wang, Y, 2008) |
| " Sedative and analgesic dosing was not clinically significantly higher in obese patients than in non-obese patients." | 1.43 | Sedation for Bronchoscopy and Complications in Obese Patients. ( Bellinger, CR; Chatterjee, AB; Haponik, E; Khan, I, 2016) |
| " Compared with the control group, a higher dosage of midazolam was administered (P = 0." | 1.39 | Risk of sedation for diagnostic esophagogastroduodenoscopy in obstructive sleep apnea patients. ( Cha, JM; Jeun, JW; Joo, KR; Lee, JI; Pack, KM; Shin, HP; Shin, WC, 2013) |
| "This study included patients with obstructive sleep apnea (OSA) and primary snoring who wish or require an alternative therapy to the gold standard, continuous positive airway pressure (CPAP)." | 1.39 | Does drug-induced sleep endoscopy change the treatment concept of patients with snoring and obstructive sleep apnea? ( Eichler, C; Hörmann, K; Maurer, JT; Sommer, JU; Stuck, BA, 2013) |
| "One hundred twenty-seven patients with obstructive sleep apnea and SUS underwent sleep endoscopy." | 1.33 | Sleep endoscopy versus modified Mallampati score in sleep apnea and snoring. ( de Vries, N; den Herder, C; van Tinteren, H, 2005) |
| "Based on a few reports that describe obstructive sleep apnea (OSA) patients as having an increased risk of acute upper airway obstruction (UAO) after pharmacological sedation, this population is less likely to receive sedation prior to surgery." | 1.31 | Preoperative sedation in pediatric patients with sleep-disordered breathing. ( Bennett, GH; Bernstein, J; Cultrara, A; Goldstein, N; Lazar, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 19 (67.86) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Roberts, C | 1 |
| Al Sayegh, R | 1 |
| Ellison, PR | 1 |
| Sedeek, K | 1 |
| Carr, MM | 1 |
| Op de Beeck, S | 1 |
| Van de Perck, E | 1 |
| Vena, D | 1 |
| Kazemeini, E | 1 |
| Dieltjens, M | 1 |
| Willemen, M | 1 |
| Wellman, A | 1 |
| Verbraecken, J | 1 |
| Sands, SA | 1 |
| Vanderveken, OM | 4 |
| Park, SM | 1 |
| Kim, DK | 2 |
| Kim, JW | 2 |
| Kim, DS | 1 |
| Kim, SD | 1 |
| Mun, SJ | 1 |
| Koo, SK | 1 |
| Cho, KS | 1 |
| Viana, A | 1 |
| Zhao, C | 1 |
| Rosa, T | 1 |
| Couto, A | 1 |
| Neves, DD | 1 |
| Araújo-Melo, MH | 1 |
| Capasso, R | 1 |
| Carrasco Llatas, M | 2 |
| Agostini Porras, G | 1 |
| Cuesta González, MT | 1 |
| Rodrigo Sanbartolomé, A | 1 |
| Giner Bayarri, P | 1 |
| Gómez-Pajares, F | 1 |
| Dalmau Galofre, J | 1 |
| Maurer, JT | 2 |
| Hohenhorst, W | 2 |
| Hamans, E | 2 |
| Lin, HS | 1 |
| Vroegop, AV | 1 |
| Anders, C | 1 |
| de Vries, N | 5 |
| Van de Heyning, PH | 1 |
| Cha, JM | 1 |
| Jeun, JW | 1 |
| Pack, KM | 1 |
| Lee, JI | 1 |
| Joo, KR | 1 |
| Shin, HP | 1 |
| Shin, WC | 1 |
| Friedrich-Rust, M | 1 |
| Welte, M | 1 |
| Welte, C | 1 |
| Albert, J | 1 |
| Meckbach, Y | 1 |
| Herrmann, E | 1 |
| Kannengiesser, M | 1 |
| Trojan, J | 1 |
| Filmann, N | 1 |
| Schroeter, H | 1 |
| Zeuzem, S | 1 |
| Bojunga, J | 1 |
| De Vito, A | 1 |
| Vanni, A | 1 |
| Bosi, M | 1 |
| Braghiroli, A | 1 |
| Campanini, A | 1 |
| Kotecha, BT | 1 |
| Maurer, J | 1 |
| Montevecchi, F | 1 |
| Piccin, O | 1 |
| Sorrenti, G | 1 |
| Vicini, C | 1 |
| Lee, CH | 2 |
| Kim, SY | 1 |
| Rhee, CS | 1 |
| Won, TB | 1 |
| Isaiah, A | 1 |
| Pereira, KD | 1 |
| Shteamer, JW | 1 |
| Dedhia, RC | 1 |
| Khan, I | 1 |
| Chatterjee, AB | 1 |
| Bellinger, CR | 1 |
| Haponik, E | 1 |
| Jiang, T | 1 |
| Chao, J | 1 |
| Cao, J | 1 |
| Wang, Y | 1 |
| Shi, L | 1 |
| Mo, JH | 1 |
| Kim, BJ | 1 |
| Kong, IG | 1 |
| Yoon, IY | 1 |
| Chung, S | 1 |
| Kim, JH | 1 |
| Choi, JK | 1 |
| Hur, YK | 1 |
| Lee, JM | 1 |
| Clark, GT | 1 |
| Gerónimo Pardo, M | 1 |
| Mateo Cerdán, CM | 1 |
| Moreno Salcedo, JM | 1 |
| Genta, PR | 1 |
| Eckert, DJ | 1 |
| Gregorio, MG | 1 |
| Danzi, NJ | 1 |
| Moriya, HT | 1 |
| Malhotra, A | 1 |
| Lorenzi-Filho, G | 1 |
| Ravesloot, MJ | 1 |
| Eichler, C | 1 |
| Sommer, JU | 1 |
| Stuck, BA | 1 |
| Hörmann, K | 1 |
| Abdullah, VJ | 1 |
| Lee, DL | 1 |
| Ha, SC | 1 |
| van Hasselt, CA | 1 |
| Cultrara, A | 1 |
| Bennett, GH | 1 |
| Lazar, C | 1 |
| Bernstein, J | 1 |
| Goldstein, N | 1 |
| den Herder, C | 1 |
| van Tinteren, H | 1 |
| Cillo, JE | 1 |
| Finn, R | 1 |
| Miller, RJ | 1 |
| Gerhardt, MA | 1 |
| Hessel, NS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056] | Phase 4 | 200 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
| Randomised Monocentric -Controlled Study to Evaluate the Efficacy and Stability of Dexmedetomidine Sedation Compared to Propofol Sedation in the Routinely Diagnostic Examination: Drug Induced Sleep Endoscopy[NCT03892122] | Phase 4 | 28 participants (Anticipated) | Interventional | 2019-03-22 | Not yet recruiting | ||
| The Role of Drug-Induced Sleep Endoscopy for the Optimisation of Treatment of Patients With Obstruction Sleep Apnoea[NCT02855515] | 120 participants (Actual) | Interventional | 2016-05-31 | Completed | |||
| Propofolsleep - A Observational Study on Cardiopulmonary and Pharyngeal Reactions While Drug Induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea Syndrome Under PSI Monitoring[NCT03224936] | 20 participants (Anticipated) | Observational | 2017-08-22 | Active, not recruiting | |||
| The Use of Transcranial Focused Ultrasound for the Treatment of Neurodegenerative Dementias[NCT04250376] | 100 participants (Anticipated) | Interventional | 2017-11-27 | Enrolling by invitation | |||
| Lymphatic System Health in Alzheimer's Disease[NCT04205539] | Phase 1 | 0 participants (Actual) | Interventional | 2021-12-10 | Withdrawn (stopped due to Pending COVID-19 pandemic) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for midazolam and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Sedative choice in drug-induced sleep endoscopy: A neuropharmacology-based review.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Endoscopy; Humans; Hypnotics and Sedatives; Midazolam; Ne | 2017 |
Sedative choice in drug-induced sleep endoscopy: A neuropharmacology-based review.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Endoscopy; Humans; Hypnotics and Sedatives; Midazolam; Ne | 2017 |
Sedative choice in drug-induced sleep endoscopy: A neuropharmacology-based review.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Endoscopy; Humans; Hypnotics and Sedatives; Midazolam; Ne | 2017 |
Sedative choice in drug-induced sleep endoscopy: A neuropharmacology-based review.
Topics: Anesthetics, Intravenous; Dexmedetomidine; Endoscopy; Humans; Hypnotics and Sedatives; Midazolam; Ne | 2017 |
2 trials available for midazolam and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
Capnographic monitoring of propofol-based sedation during colonoscopy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Apnea; Body Mass Index; Capnography; Colono | 2014 |
[The value of video laryngoscope in localization diagnosis of upper airway stricture in obstructive sleep apnea-hypopnea syndrome during drug-induced sleep].
Topics: Adult; Female; Humans; Laryngoscopes; Male; Midazolam; Middle Aged; Sleep Apnea, Obstructive | 2008 |
25 other studies available for midazolam and Apnea, Obstructive Sleep
| Article | Year |
|---|---|
How Pediatric Anesthesiologists Manage Children with OSA Undergoing Tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Airway Extubation; Analgesics; Anesthesiology; Anesthetics; Anti-Infla | 2020 |
Flow-Identified Site of Collapse During Drug-Induced Sleep Endoscopy: Feasibility and Preliminary Results.
Topics: Aged; Endoscopy; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Midd | 2021 |
Effect of physical stress on drug-induced sleep endoscopy for obstructive sleep apnea.
Topics: Adult; Case-Control Studies; Endoscopy; Epiglottis; Exercise Test; Female; Humans; Hypnotics and Sed | 2017 |
Does drug-induced sleep endoscopy predict surgical success of limited palatal muscle resection in patients with obstructive sleep apnea?
Topics: Adult; Cephalometry; Female; Humans; Hypnotics and Sedatives; Laryngoscopy; Male; Midazolam; Middle | 2018 |
The Effect of Sedating Agents on Drug-Induced Sleep Endoscopy Findings.
Topics: Adult; Dexmedetomidine; Endoscopy; Epiglottis; Female; Humans; Hypnotics and Sedatives; Male; Midazo | 2019 |
Drug-induced sleep endoscopy: a two drug comparison and simultaneous polysomnography.
Topics: Adult; Double-Blind Method; Endoscopy; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Mid | 2014 |
Evaluation of drug-induced sleep endoscopy as a patient selection tool for implanted upper airway stimulation for obstructive sleep apnea.
Topics: Airway Obstruction; Electric Stimulation; Endoscopy; Female; Fiber Optic Technology; Humans; Hypnoti | 2013 |
Risk of sedation for diagnostic esophagogastroduodenoscopy in obstructive sleep apnea patients.
Topics: Adult; Case-Control Studies; Chi-Square Distribution; Deep Sedation; Endoscopy, Digestive System; Fe | 2013 |
European position paper on drug-induced sedation endoscopy (DISE).
Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based | 2014 |
European position paper on drug-induced sedation endoscopy (DISE).
Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based | 2014 |
European position paper on drug-induced sedation endoscopy (DISE).
Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based | 2014 |
European position paper on drug-induced sedation endoscopy (DISE).
Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based | 2014 |
Changes in site of obstruction in obstructive sleep apnea patients according to sleep position: a DISE study.
Topics: Adult; Anesthesia, Intravenous; Endoscopy; Female; Gravitation; Humans; Larynx; Male; Midazolam; Mid | 2015 |
Outcomes after adenotonsillectomy using a fixed anesthesia protocol in children with obstructive sleep apnea.
Topics: Adenoidectomy; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Int | 2015 |
Sedation for Bronchoscopy and Complications in Obese Patients.
Topics: Anesthetics, Intravenous; Body Mass Index; Bronchoscopy; Conscious Sedation; Female; Fentanyl; Human | 2016 |
Evaluation of soft palate changes using sleep videofluoroscopy in patients with obstructive sleep apnea.
Topics: Adult; Aged; Female; Fluoroscopy; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Pal | 2009 |
Effects of mandibular advancement on upper airway dimension and collapsibility in patients with obstructive sleep apnea using dynamic upper airway imaging during sleep.
Topics: Adult; Aged; Anatomy, Cross-Sectional; Female; Humans; Hypnotics and Sedatives; Image Processing, Co | 2010 |
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].
Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatogra | 2010 |
Critical closing pressure during midazolam-induced sleep.
Topics: Adult; Humans; Male; Midazolam; Middle Aged; Polysomnography; Pressure; Respiratory Mechanics; Respi | 2011 |
One hundred consecutive patients undergoing drug-induced sleep endoscopy: results and evaluation.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Cohort Studies; Endoscopy; Female; Humans; Male; | 2011 |
Does drug-induced sleep endoscopy change the treatment concept of patients with snoring and obstructive sleep apnea?
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Endoscopy; Epiglottis; Female; Humans; Mal | 2013 |
Drug-induced sleep endoscopy (DISE) for non-CPAP treatment selection in patients with sleep-disordered breathing.
Topics: Anesthetics, Intravenous; Endoscopy; Female; Humans; Male; Midazolam; Sleep; Sleep Apnea, Obstructiv | 2013 |
Sleep endoscopy with midazolam: sedation level evaluation with bispectral analysis.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Consciousness Monitors; Electromyography; Endoscopy; | 2013 |
Preoperative sedation in pediatric patients with sleep-disordered breathing.
Topics: Academic Medical Centers; Adenoidectomy; Adolescent; Airway Resistance; Child; Child, Preschool; Con | 2002 |
Sleep endoscopy versus modified Mallampati score in sleep apnea and snoring.
Topics: Airway Obstruction; Endoscopy; Female; Humans; Hypnotics and Sedatives; Larynx; Male; Midazolam; Mid | 2005 |
Hemodynamics and oxygen saturation during intravenous sedation for office-based laser-assisted uvuloplasty.
Topics: Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Intravenous; Blood Pressure; Consci | 2005 |
Uvular edema secondary to snoring under deep sedation.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Arm; Brachial Plexus; Edema; Fentanyl; Humans; | 2006 |
Diagnostic work-up of socially unacceptable snoring. II. Sleep endoscopy.
Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Endoscopy; Female; GABA Modulators; Humans; Male; M | 2002 |