midazolam has been researched along with Anxiety in 346 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect on pre-operative anxiety of premedication with midazolam, playing video games or watching a cartoon about anaesthesia." | 9.41 | Which is good for pre-operative anxiety? Midazolam, video games or teaching with cartoons: A randomised trial. ( Bolat, M; Donmez, A; Polat, R; Sakızcı Uyar, B, 2021) |
| "The purpose of this study was to compare effects of tablet-based interactive distraction (TBID; 1 minute preseparation) with oral midazolam (15 to 45 minutes of preseparation) on preoperative anxiety, emergence delirium, and postanesthesia length of stay in children, 4 to 12 years undergoing outpatient surgery." | 9.30 | Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay. ( Cazzell, MA; Pearcy, T; Stewart, B, 2019) |
| "The aim of this study was to determine whether an infusion of dexmedetomidine prior to hernia repair in children provides better postoperative anxiety outcomes that a preoperative infusion of midazolam." | 9.30 | The comparison of dexmedetomidine and midazolam premedication on postoperative anxiety in children for hernia repair surgery: A randomized controlled trial. ( Du, Z; Guo, QL; Qu, SQ; Song, ZB; Wei, SW; Xiang, Z; Zhang, XY, 2019) |
| "This study adds new encouraging data, further supporting the potential use of melatonin premedication in reducing anxiety and improving compliance to induction of anaesthesia in children undergoing surgery." | 9.24 | Premedication with melatonin vs midazolam: efficacy on anxiety and compliance in paediatric surgical patients. ( Alibrandi, A; Arena, S; Cuzzocrea, F; D'Angelo, G; Gitto, E; Gravina, MR; Gugliandolo, MC; Impellizzeri, P; Larcan, R; Marseglia, L; Montalto, AS; Romeo, C; Russo, T; Vinci, E, 2017) |
| "The group that was premedicated with dextromethorphan had lower complaint scores, significantly less coughing, significantly less stress assessed by the patient and the physician evaluation, shorter total procedure time, and fewer midazolam requirements during FB (P-value <0." | 9.24 | The Effect of Dextromethorphan Premedication on Cough and Patient Tolerance During Flexible Bronchoscopy: A Randomized, Double-blind, Placebo-controlled Trial. ( Amini, S; Ghalamkari, M; Khatuni, M; Peiman, S; Rahimi, B, 2017) |
| "Patients receiving ketamine for refractory depression and anxiety report dissociative symptoms in the first 60 min post-dose." | 9.24 | Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders. ( Castle, C; Glue, P; Gray, A; Neehoff, S, 2017) |
| "To evaluate the effects of intranasal midazolam premedication on children who undergoing inhaled induction of anesthesia with sevoflurane." | 9.22 | [Effects of intranasal midazolam premedication on inhaled induction of anesthesia with sevoflurane of pediatric patients]. ( Wang, R; Wang, WH, 2016) |
| "To estimate the effect of oral midazolam on patient pain and anxiety perception during first-trimester surgical abortion." | 9.20 | An Evaluation of Oral Midazolam for Anxiety and Pain in First-Trimester Surgical Abortion: A Randomized Controlled Trial. ( Bayer, LL; Bednarek, PH; Edelman, AB; Fu, R; Jensen, JT; Lambert, WE; Miller, K; Nichols, MD, 2015) |
| "The mean difference (95% CI) in the increase of anxiety at parental separation between the TBID and the midazolam group was -9 (-2." | 9.19 | Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial. ( De Oliveira, GS; Jesdale, BM; McMullan, S; Rosenblatt, A; Roth, A; Seiden, SC; Sequera-Ramos, L; Suresh, S, 2014) |
| "To compare the effects of intranasal midazolam versus different doses of intranasal ketamine on reducing preoperative pediatric anxiety." | 9.16 | Comparison of the effects of intranasal midazolam versus different doses of intranasal ketamine on reducing preoperative pediatric anxiety: a prospective randomized clinical trial. ( Adeli, N; Hosseini Jahromi, SA; Hosseini Valami, SM; Yazdi, Z, 2012) |
| "The single use of mask preconditioning has a better influence than midazolam for increasing mask acceptance during inhalational induction and reducing postoperative mask fear, reducing the anxiety level during induction, improving induction compliance and shortening the total mask time." | 9.16 | Effects of the combination of mask preconditioning with midazolam pretreatment on anxiety and mask acceptance during pediatric inhalational induction and postoperative mask fear in children. ( Finley, GA; Huang, ZH; Lan, YP; Zuo, YX, 2012) |
| "There was no difference in Modified Yale Preoperative Anxiety Scale scores in children randomized to midazolam or placebo." | 9.15 | The efficacy of oral midazolam for decreasing anxiety in children undergoing voiding cystourethrogram: a randomized, double-blind, placebo controlled study. ( Austin, PF; Campigotto, M; Chen, C; Coplen, DE; Ferguson, GG; Royer, ME; Traxel, EJ; Yan, Y, 2011) |
| "Propofol and midazolam are commonly used in the ICU to alleviate physical and psychological disturbances in consequence of anxiety." | 9.12 | Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety. ( Chen, FC; Hsiao, PC; Liaw, WJ; Tang, YY; Wang, KY; Yue-Cune Chang, YH, 2006) |
| "These findings indicate that children receiving clonidine or DEX preoperatively have similar levels of anxiety and sedation postoperatively as those receiving midazolam." | 9.12 | Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children. ( Auler, JO; Bandeira, D; Bertacchi, MF; Schmidt, AP; Simões, CM; Valinetti, EA, 2007) |
| "Parents and nurses reported reduced anxiety, discomfort, and procedure problems for children in the midazolam group and would prefer the same medication at next procedure." | 9.09 | Midazolam nasal spray reduces procedural anxiety in children. ( Andréasson, S; Gordh, T; Kreuger, A; Ljungman, G; Sörensen, S, 2000) |
| "The minimum time interval between administration of oral midazolam and separation of children from their parents that ensures good anterograde amnesia has not been previously determined." | 9.09 | Midazolam: effects on amnesia and anxiety in children. ( Alexander, G; Hofstadter, MB; Kain, ZN; Krivutza, DM; Mayes, LC; Reznick, JS; Wang, SM, 2000) |
| "To assess and compare the impact of overnight sedation with midazolam or propofol on anxiety and depression levels, as well as sleep quality, in non-intubated patients in intensive care." | 9.08 | Overnight sedation with midazolam or propofol in the ICU: effects on sleep quality, anxiety and depression. ( Borgeat, A; Fuchs-Buder, T; Gachoud, JP; Suter, PM; Treggiari-Venzi, M, 1996) |
| "To assess the effects of melatonin on preoperative and postoperative anxiety compared to placebo or benzodiazepines." | 9.05 | Melatonin for preoperative and postoperative anxiety in adults. ( Madsen, BK; Møller, AM; Rosenberg, J; Zetner, D, 2020) |
| "To assess the effect of melatonin on pre- and postoperative anxiety in adults when comparing melatonin with placebo or when comparing melatonin with benzodiazepines." | 8.91 | Melatonin for pre- and postoperative anxiety in adults. ( Gögenur, I; Halladin, NL; Hansen, MV; Møller, AM; Rosenberg, J, 2015) |
| "This retrospective study compares the efficacy and safety of variable dosing of Midazolam (Mid) with and without Meperidine (Mep) combinations for managing varying levels of anxiety and uncooperative behavior of young pediatric dental patients over a thirty-five-year period." | 8.12 | Retrospective Comparisons of the Efficacy and Safety of Variable dosing of Midazolam with and without Meperidine for Management of Varying Levels of Anxiety of Pediatric Dental Patients: 35 years of Sedation Experience. ( Nathan, JE, 2022) |
| "In our practice, patients undergoing bilateral cataract surgery complain of more significant pain after the 2nd eye surgery." | 7.85 | [Prevalence and causes of pain after cataract surgery: Comparison of 1st and 2nd eyes]. ( Amzallag, T; Gayadine-Harricham, Y, 2017) |
| "To evaluate whether midazolam with propofol target controlled infusion (TCI) intravenous sedation during the mandibular third molar extraction influences patients'perioperative anxiety." | 7.85 | [Intravenous sedation with midazolam and propofol target controlled infusion on patients'perioperative anxiety under the mandibular third molar extraction]. ( Guan, M; Liu, Y; Wang, TJ, 2017) |
| "The aim of this study was to examine the effects of benzodiazepine (midazolam) administration on rat conditioned fear responses and on local brain activity (c-Fos and CRF expressions) of low- (LR) and high- (HR)anxiety rats after the first and second contextual fear test sessions." | 7.81 | Midazolam treatment before re-exposure to contextual fear reduces freezing behavior and amygdala activity differentially in high- and low-anxiety rats. ( Krząścik, P; Lehner, M; Płaźnik, A; Skórzewska, A; Sobolewska, A; Turzyńska, D; Wisłowska-Stanek, A, 2015) |
| "Midazolam requires BZD-sensitive α1- and α2-containing GABAA receptors in order to escalate aggression and α2- and α3-containing receptors to reduce social anxiety-like behavior." | 7.81 | α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice. ( Chen, Y; Chu, A; DeBold, JF; Hwa, LS; Miczek, KA; Newman, EL; Rudolph, U; Smith, KS; Takahashi, A, 2015) |
| "This study aimed to compare the influences ofmidazolam and dexmedetomidine infusion on anxiety scores in patients undergoing surgery with regional anesthesia." | 7.79 | The effects of midazolam and dexmedetomidine infusion on peri-operative anxiety in regional anesthesia. ( Apan, A; Köse, EA; Oz, G; Rezaki, H; Senses, E, 2013) |
| " The present study focused on the long-term effects of developmentally altered allopregnanolone (AlloP) levels on anxiety-like behavior in adulthood." | 7.78 | Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats. ( Darbra, S; Pallarès, M, 2012) |
| "The contribution of GABAergic mechanisms to rat emotional behavior in two animal models of anxiety (open field test of neophobia and aversively conditioned freezing reaction), was confirmed by pharmacological analysis, using anxiolytic (midazolam) and anxiogenic (picrotoxin) compounds." | 7.72 | Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis. ( Bidziński, A; Członkowska, AI; Lehner, M; Maciejak, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J; Turzyńska, D; Wisłowska, A; Zienowicz, M, 2003) |
| "We investigated the relationship between the pharmacokinetic variables of oral midazolam and patients' state/trait anxiety and personality." | 7.71 | The effect of anxiety and personality on the pharmacokinetics of oral midazolam. ( Eisenhardt, S; Martens-Lobenhoffer, J; Meyer, FP; Röse, W; Tröger, U, 2001) |
| " The opiate antagonist naloxone (1 mg/kg and 10 mg/kg) neither blocked this open arm-induced antinociception (OAIA) nor modified indices of anxiety in EPM." | 7.70 | Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam. ( Canto-de-Souza, A; da-Costa, M; Fornari, RV; Graeff, FG; Nunes-de-Souza, RL; Pelá, IR, 2000) |
| "Forty-five breast cancer patients were randomized into three groups: Group I--chemotherapy, control, Group II--midazolam+chemotherapy, and Group III--propofol+chemotherapy." | 6.71 | Effect of sedation with midazolam or propofol on patient's comfort during cancer chemotherapy infusion: a prospective, randomized, double-blind study in breast cancer patients. ( Argun, G; Baran, O; Dikmen Mentes, S; Ertunc, FN; Unsal, D, 2005) |
| " The control group and the test groups were comparable with regard to biological data, duration of operation, applied dosage of local anaesthetics and actual anxiety before operation." | 6.68 | [Analgesia-sedation for maxillo-facial surgery with midazolam-pentazocine and miazolam-ketamine. Clinical double-blind study of anxiety, analgesia, sedation and amnesia]. ( Daubländer, M; Dick, W; Lipp, M; Sebastian, M, 1995) |
| "Midazolam was found to be the drug of preference for the majority of patients." | 6.67 | Midazolam versus fentanyl as premedication for painful procedures in children with cancer. ( Conner, K; Dickson, N; Luzins, J; McGorray, S; Reilly, K; Sandler, ES; Weyman, C, 1992) |
| "Midazolam is a short-acting benzodiazepine with anxiolytic, hypnotic, and antegrade amnestic effects." | 6.67 | The effect of oral midazolam on anxiety of preschool children during laceration repair. ( Bonadio, WA; Glaeser, PW; Hennes, HM; Losek, JD; Smith, DS; Wagner, V; Walsh-Kelly, CM, 1990) |
| "Midazolam is a good premedicant for general or regional anesthesia." | 6.37 | Use of midazolam hydrochloride in anesthesia. ( Khanderia, U; Pandit, SK, 1987) |
| " Eighty-two patients with self-reported dental anxiety either completed treatment with dentist-administered cognitive behavioural therapy (D-CBT, n = 36), or received dental treatment while sedated with midazolam combined with the systemized communication technique "The Four Habits Model" (Four Habits/midazolam, n = 41)." | 5.69 | Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety. ( Hauge, MS; Stora, B; Willumsen, T, 2023) |
| " In pediatric patient with and without anxiety, midazolam separation from the family and accepting the anesthesia mask is easiest in midazolam, second in those who are given a tablet computer." | 5.51 | The effect of using tablet computer on surgical stress: A single-blinded randomized controlled trial. ( Evren Sahin, K; Karkiner, A, 2022) |
| "We investigated the effect on pre-operative anxiety of premedication with midazolam, playing video games or watching a cartoon about anaesthesia." | 5.41 | Which is good for pre-operative anxiety? Midazolam, video games or teaching with cartoons: A randomised trial. ( Bolat, M; Donmez, A; Polat, R; Sakızcı Uyar, B, 2021) |
| " We compared preanesthetic administration of midazolam to a psychological strategy of walking the children through the operating room and playfully demonstrating anesthesia equipment." | 5.34 | Psychology versus medication for preanesthesia preparation of children: a randomized controlled trial. ( Kimberger, O; Marhofer, D; Marhofer, P; Ohmann, S; Schmid, W; Triffterer, L, 2020) |
| "The purpose of this study was to compare effects of tablet-based interactive distraction (TBID; 1 minute preseparation) with oral midazolam (15 to 45 minutes of preseparation) on preoperative anxiety, emergence delirium, and postanesthesia length of stay in children, 4 to 12 years undergoing outpatient surgery." | 5.30 | Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay. ( Cazzell, MA; Pearcy, T; Stewart, B, 2019) |
| "To examine the effect of high baseline anxiety on response to ketamine versus midazolam (active placebo) in treatment-resistant depression (TRD)." | 5.30 | Efficacy of intravenous ketamine treatment in anxious versus nonanxious unipolar treatment-resistant depression. ( Cusin, C; Debattista, C; Fava, M; Flynn, M; Freeman, MP; Hock, RS; Hoeppner, B; Ionescu, DF; Iosifescu, DV; Mathew, SJ; Papakostas, GI; Salloum, NC; Sanacora, G; Trivedi, MH, 2019) |
| "The aim of this study was to determine whether an infusion of dexmedetomidine prior to hernia repair in children provides better postoperative anxiety outcomes that a preoperative infusion of midazolam." | 5.30 | The comparison of dexmedetomidine and midazolam premedication on postoperative anxiety in children for hernia repair surgery: A randomized controlled trial. ( Du, Z; Guo, QL; Qu, SQ; Song, ZB; Wei, SW; Xiang, Z; Zhang, XY, 2019) |
| "This study was designed to determine whether transport of a paediatric inpatient in a children's ride-on toy car has an effect on perioperative levels of anxiety compared with transport on a hospital gurney with or without oral midazolam premedication." | 5.27 | The effectiveness of transport in a toy car for reducing preoperative anxiety in preschool children: a randomised controlled prospective trial. ( Chen, YQ; Huang, Y; Liu, PP; Sun, Y; Wu, C; Wu, JZ; Xu, WH; Zhang, MZ; Zhang, RD; Zheng, JJ, 2018) |
| "Midazolam premedication did not reduce the level of anxiety." | 5.27 | Randomized controlled trial assessing the effectiveness of midazolam premedication as an anxiolytic, analgesic, sedative, and hemodynamic stabilizer. ( Do, W; Hwang, BY; Jeon, S; Kim, HK; Kwon, JY; Lee, HJ; Yun, J, 2018) |
| "Based on the theory that impaired perception following oral zolpidem administration would suppress the development of anxiety, we sought to compare zolpidem to midazolam for pediatric preoperative anxiety." | 5.27 | A comparison of midazolam and zolpidem as oral premedication in children, a prospective randomized double-blinded clinical trial. ( Andrews, G; Applegate, RL; Austin, B; Cano, S; Hanna, AH; Leiter, P; Ramsingh, D; Sullivan-Lewis, W; Wallace, D, 2018) |
| " Within the three study groups, no significant change was objectified in the anxiety level from baseline to separation from parents (mean change in mYPAS midazolam group: 2." | 5.24 | Childhood preoperative anxiolysis: Is sedation and distraction better than either alone? A prospective randomized study. ( Bringuier, S; Capdevila, X; Dadure, C; Lefauconnier, A; Raux, O; Sola, C, 2017) |
| "The group that was premedicated with dextromethorphan had lower complaint scores, significantly less coughing, significantly less stress assessed by the patient and the physician evaluation, shorter total procedure time, and fewer midazolam requirements during FB (P-value <0." | 5.24 | The Effect of Dextromethorphan Premedication on Cough and Patient Tolerance During Flexible Bronchoscopy: A Randomized, Double-blind, Placebo-controlled Trial. ( Amini, S; Ghalamkari, M; Khatuni, M; Peiman, S; Rahimi, B, 2017) |
| "Patients receiving ketamine for refractory depression and anxiety report dissociative symptoms in the first 60 min post-dose." | 5.24 | Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders. ( Castle, C; Glue, P; Gray, A; Neehoff, S, 2017) |
| " Eighty-two females undergoing breast cancer surgery with propofol-remifentanil anesthesia were enrolled and randomized to receive midazolam 0." | 5.24 | Can quality of recovery be enhanced by premedication with midazolam?: A prospective, randomized, double-blind study in females undergoing breast surgery. ( Kim, MH; Kim, MS; Lee, JH; Lee, JR; Seo, JH, 2017) |
| "The efficacy of midazolam as premedication in children for providing pre-operative sedation and reducing parental separation anxiety has been well established." | 5.24 | Comparison of ease of administration of intranasal midazolam spray and oral midazolam syrup by parents as premedication to children undergoing elective surgery. ( Kamaladevi, RK; Manoj, M; Satya Prakash, MVS; Swaminathan, S, 2017) |
| "Intranasal dexmedetomidine is an alternative anxiolytic medication to intranasal midazolam for pediatric laceration repairs, performing similarly in our study, except that patients who received dexmedetomidine had less anxiety at the time of positioning for procedure." | 5.22 | Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department. ( Hayes, KR; Ivan, Y; McDowell, ER; Neville, DN; Pitetti, RD, 2016) |
| "To evaluate the effects of intranasal midazolam premedication on children who undergoing inhaled induction of anesthesia with sevoflurane." | 5.22 | [Effects of intranasal midazolam premedication on inhaled induction of anesthesia with sevoflurane of pediatric patients]. ( Wang, R; Wang, WH, 2016) |
| "When administered ~5 min prior to entering the OR, propofol, 20mg IV, was as effective as midazolam 2mg IV in reducing anxiety." | 5.22 | Propofol versus midazolam for premedication: a placebo‑controlled, randomized double‑blinded study. ( Anand, KK; Cao, X; Elvir Lazo, OL; Hausman, J; Hemaya, EG; Hernandez Conte, A; Tang, J; Wender, RH; White, PF; Yumul, F; Yumul, R; Zhang, X, 2016) |
| "To estimate the effect of oral midazolam on patient pain and anxiety perception during first-trimester surgical abortion." | 5.20 | An Evaluation of Oral Midazolam for Anxiety and Pain in First-Trimester Surgical Abortion: A Randomized Controlled Trial. ( Bayer, LL; Bednarek, PH; Edelman, AB; Fu, R; Jensen, JT; Lambert, WE; Miller, K; Nichols, MD, 2015) |
| "Distraction technology suitable for the perioperative setting is readily available, but there is little evidence to show how it compares with oral midazolam in managing anxiety." | 5.17 | Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children. ( Kerimoglu, B; Neuman, A; Paul, J; Stefanov, DG; Twersky, R, 2013) |
| "Intranasal dexmedetomidine and midazolam are equally effective in decreasing anxiety upon separation from parents; however, midazolam is superior in providing satisfactory conditions during mask induction." | 5.16 | Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia. ( Akin, A; Aksu, R; Altuntas, R; Bayram, A; Boyaci, A; Esmaoglu, A; Tosun, Z, 2012) |
| "To compare the effects of intranasal midazolam versus different doses of intranasal ketamine on reducing preoperative pediatric anxiety." | 5.16 | Comparison of the effects of intranasal midazolam versus different doses of intranasal ketamine on reducing preoperative pediatric anxiety: a prospective randomized clinical trial. ( Adeli, N; Hosseini Jahromi, SA; Hosseini Valami, SM; Yazdi, Z, 2012) |
| "Midazolam and ketamine are useful for oral premedication in children to allay anxiety." | 5.15 | Low- versus high-dose combination of midazolam-ketamine for oral premedication in children for ophthalmologic surgeries. ( Darlong, V; Garg, R; Pandey, R; Punj, J; Shende, D; Singh, M, 2011) |
| "To determine if specially trained professional clowns allayed preoperative anxiety and resulted in a smooth anesthetic induction compared to the use of midazolam or no intervention." | 5.14 | Clowns for the prevention of preoperative anxiety in children: a randomized controlled trial. ( Dobija, N; Golan, G; Keidan, I; Perel, A; Tighe, P, 2009) |
| "Relaxing music decreases the level of anxiety in a pre-operative setting to a greater extent than orally administrated midazolam." | 5.14 | Relaxing music as pre-medication before surgery: a randomised controlled trial. ( Bringman, H; Bringman, S; Giesecke, K; Thörne, A, 2009) |
| " We investigate whether anxiety levels at removal of wires may be reduced using oral midazolam." | 5.14 | Oral midazolam for removal of Kirschner wires in the children's orthopaedic outpatient department: a randomized controlled trial. ( Allgar, V; Burton, D; Cullen, E; Lewis, H; Templeton, P; Wilson, R, 2010) |
| "In 139 patients anxiety, sedation and adverse effects were measured at 6 consecutive perioperative time points after administration of midazolam, clonidine or a placebo." | 5.14 | [Quality of premedication and patient satisfaction after premedication with midazolam, clonidine or placebo : Randomized double-blind study with age-adjusted dosage]. ( Ivleva-Sauerborn, A; Seifert, B; Spahn, DR; Zalunardo, MP, 2010) |
| "PPIA+clown intervention is more effective in reducing anxiety in children during the preoperative period than PPIA alone or PPIA+oral midazolam." | 5.14 | Parental presence, clowns or sedative premedication to treat preoperative anxiety in children: what could be the most promising option? ( Caprilli, S; Messeri, A; Vagnoli, L, 2010) |
| "Given the potentially important effects that age and gender may have on midazolam premedication, this study aimed at determining if these factors alter anxiety, sedation, and cardiorespiratory outcomes when administering two different doses of i." | 5.13 | Effects of age and gender on intravenous midazolam premedication: a randomized double-blind study. ( Chen, PY; Chia, YY; Hsu, MC; Shaw, FZ; Sun, GC, 2008) |
| "To investigate the effects of midazolam on emotional reactivity during induction of anesthesia in a pediatric day surgery setting." | 5.12 | High levels of impulsivity may contraindicate midazolam premedication in children. ( Buffett-Jerrott, S; Finley, GA; Millington, D; Stewart, SH; Wright, KD, 2006) |
| "Propofol and midazolam are commonly used in the ICU to alleviate physical and psychological disturbances in consequence of anxiety." | 5.12 | Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety. ( Chen, FC; Hsiao, PC; Liaw, WJ; Tang, YY; Wang, KY; Yue-Cune Chang, YH, 2006) |
| "These findings indicate that children receiving clonidine or DEX preoperatively have similar levels of anxiety and sedation postoperatively as those receiving midazolam." | 5.12 | Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children. ( Auler, JO; Bandeira, D; Bertacchi, MF; Schmidt, AP; Simões, CM; Valinetti, EA, 2007) |
| " In addition postoperative morphine requirement, anxiety, and vomiting were not affected by the music during general anesthesia." | 5.12 | The impact of music on postoperative pain and anxiety following cesarean section. ( Abul-Qasim, A; Ali, SM; Reza, N; Reza, TH; Saeed, K, 2007) |
| "To evaluate the effect of midazolam on the global perioperative experience, including patient satisfaction, postoperative nausea and vomiting, postoperative pain, and perioperative anxiety and amnesia." | 5.11 | Preoperative intravenous midazolam: benefits beyond anxiolysis. ( Bauer, KP; Dom, PM; O'Flaherty, JE; Ramirez, AM, 2004) |
| "The median (interquartile range) anxiety score during the procedure in the midazolam group was significantly lower than that in the control group (2." | 5.11 | Premedication with orally administered midazolam in adults undergoing diagnostic upper endoscopy: a double-blind placebo-controlled randomized trial. ( Au Yeung, AC; Chan, YL; Chung, SC; Lau, JY; Lee, YT; Mui, LM; Ng, EK; Teoh, AY, 2005) |
| "Melatonin was not only as effective as midazolam in alleviating preoperative anxiety in children, but it was also associated with a tendency towards faster recovery, lower incidence of excitement postoperatively and a lower incidence of sleep disturbance at week 2 postoperatively." | 5.11 | Melatonin vs. midazolam premedication in children: a double-blind, placebo-controlled study. ( Albassam, A; Aldammas, F; Alotibi, W; Naguib, M; Riad, W; Samarkandi, A; Thalaj, A, 2005) |
| " Although the visual analog scale, Observer's Assessment of Alertness/Sedation Scale, and State and Trait Anxiety Inventory-State Anxiety test did not show statistically significant differences, the State and Trait Anxiety Inventory-Trait Anxiety score was found to be lower in the music group (group 2) than in the midazolam group (group 1)." | 5.10 | Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy. ( Basar, H; Basar, M; Batislam, E; Ferhat, M; Ozcan, S; Yilmaz, E, 2003) |
| "Children who received the midazolam/Syrpalta mixture had less anxiety at 15 min (P = 0." | 5.10 | A paediatric trial comparing midazolam/Syrpalta mixture with premixed midazolam syrup (Roche). ( Chuang, AZ; Farag, A; Hanna, E; Kee, SS; Khalil, SN; Vije, HN, 2003) |
| "Both clonidine as well as midazolam showed a significant reduction of the state-anxiety over time (p < 0,001)." | 5.10 | [Clonidine vs. Midazolam for premedication - comparison of the anxiolytic effect by using the STAI-test]. ( Frank, T; Heinke, W; Schmädicke, I; Wehner, M, 2002) |
| "Oral midazolam significantly reduces anxiety and pain during flexible sigmoidoscopy as assessed by both patients and physicians." | 5.09 | A double-blind placebo controlled trial of oral midazolam as premedication before flexible sigmoidoscopy. ( Chen, ST; Clarkston, WK; Cuddy, PG; Dierenfeldt, WT; Jonnalagadda, SS; Kuganeswaran, E; Pandya, PK; Quiason, SG; Smith, OJ, 1999) |
| "Parents and nurses reported reduced anxiety, discomfort, and procedure problems for children in the midazolam group and would prefer the same medication at next procedure." | 5.09 | Midazolam nasal spray reduces procedural anxiety in children. ( Andréasson, S; Gordh, T; Kreuger, A; Ljungman, G; Sörensen, S, 2000) |
| " The addition of alfentanil and or propofol to midazolam was evaluated with regard to hemodynamic variables, respiratory rate, pain, anxiety, sedation, postoperative recovery and patient satisfaction." | 5.09 | A comparison of midazolam, alfentanil and propofol for sedation in outpatient intraocular surgery. ( Chung, F; Fortier, J; Krishnathas, A; Marshall, SI; McHardy, FE, 2000) |
| "5 mg/kg oral midazolam has no additive effects in terms of reducing a child's anxiety." | 5.09 | Parental presence and a sedative premedicant for children undergoing surgery: a hierarchical study. ( Caramico, LA; Hofstadter, MB; Kain, ZN; Krivutza, DM; Mayes, LC; Wang, SM, 2000) |
| "The minimum time interval between administration of oral midazolam and separation of children from their parents that ensures good anterograde amnesia has not been previously determined." | 5.09 | Midazolam: effects on amnesia and anxiety in children. ( Alexander, G; Hofstadter, MB; Kain, ZN; Krivutza, DM; Mayes, LC; Reznick, JS; Wang, SM, 2000) |
| "Demographic data, hemodynamic variables, sedation and anxiety scores, amnesia, patient and cardiologist satisfaction, and adverse effects were evaluated and compared among coronary angiography patients taking midazolam, midazolam and fentanyl, or placebo before the procedure." | 5.09 | Comparison of midazolam with or without fentanyl for conscious sedation and hemodynamics in coronary angiography. ( Aykent, R; Baris, S; Karakaya, D; Kirdar, K; Sagkan, O; Tür, A, 2001) |
| "3 mg/kg) and buffered lidocaine in reducing the anxiety associated with the repair of childhood lacerations." | 5.08 | A randomized, controlled trial of oral midazolam and buffered lidocaine for suturing lacerations in children (the SLIC Trial). ( Fatovich, DM; Jacobs, IG, 1995) |
| "Applying the principle and equipment of patient-controlled analgesia, this double-blind randomised study was designed to determine the premedication dose of midazolam and to provide information about the need for preoperative anxiety control." | 5.08 | Patient-controlled premedication by i.v. midazolam for ambulatory surgery. ( Bernard, JM; Faintreny, A; Lienhart, A; Souron, R, 1996) |
| " A high incidence of pain with drug injection was noted among patients receiving propofol (80%)." | 5.08 | Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients. ( Ganapathy, S; Gelb, AW; Herrick, IA; Kirkby, J, 1997) |
| "To assess and compare the impact of overnight sedation with midazolam or propofol on anxiety and depression levels, as well as sleep quality, in non-intubated patients in intensive care." | 5.08 | Overnight sedation with midazolam or propofol in the ICU: effects on sleep quality, anxiety and depression. ( Borgeat, A; Fuchs-Buder, T; Gachoud, JP; Suter, PM; Treggiari-Venzi, M, 1996) |
| "This study was performed to evaluate the effect of midazolam, as premedication before intravenous conscious sedation, on preprocedural, procedural, and post-procedural patient comfort and anxiety in children undergoing endoscopy." | 5.08 | Placebo-controlled trial assessing the use of oral midazolam as a premedication to conscious sedation for pediatric endoscopy. ( Liacouras, CA; Mascarenhas, M; Poon, C; Wenner, WJ, 1998) |
| "Both midazolam and parental presence during induction of anesthesia are routinely used to treat preoperative anxiety in children." | 5.08 | Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective? ( Caramico, LA; Hofstadter, MB; Kain, ZN; Mayes, LC; Wang, SM, 1998) |
| "A single dose of oral or nasal midazolam results in reduced anxiety and few complications in selected children undergoing laceration repair in the ED." | 5.07 | Nasal versus oral midazolam for sedation of anxious children undergoing laceration repair. ( Connors, K; Terndrup, TE, 1994) |
| "The goal of this study was to assess the degree of postoperative anxiety flumazenil might provide in patients when used to reverse the sedation induced by midazolam." | 5.06 | [Does flumazenil, a benzodiazepine antagonist used during the anesthesia recovery period, have an anxiogenic effect?]. ( Beauvoir, C; du Cailar, J; Pares-Herbute, N; Peschaud, JL, 1989) |
| "The observed effect of midazolam on anxiety is equivocal in part because previous studies have not ruled out pre-treatment differences in anxiety scores between patients who received midazolam and those who did not (controls)." | 5.06 | A re-evaluation of the anxiolytic properties of intramuscular midazolam. ( Artru, AA; Dhamee, MS; Seifen, AB; Wright, B, 1986) |
| "To assess the effects of melatonin on preoperative and postoperative anxiety compared to placebo or benzodiazepines." | 5.05 | Melatonin for preoperative and postoperative anxiety in adults. ( Madsen, BK; Møller, AM; Rosenberg, J; Zetner, D, 2020) |
| "Dexmedetomidine is effective in decreasing anxiety upon separation from parents, decreasing postoperative agitation, and providing more effective postoperative analgesia when compared with midazolam." | 4.91 | Dexmedetomidine vs midazolam as preanesthetic medication in children: a meta-analysis of randomized controlled trials. ( Borghi, G; Febres, D; Frati, E; Landoni, G; Pasin, L; Testa, V; Zangrillo, A, 2015) |
| "To assess the efficacy of midazolam for anxiety control in third molar extraction surgery." | 4.91 | The anxiolytic effect of midazolam in third molar extraction: a systematic review. ( Chen, Q; Gao, Y; Ge, L; Wang, H; Wang, L, 2015) |
| "To assess the effect of melatonin on pre- and postoperative anxiety in adults when comparing melatonin with placebo or when comparing melatonin with benzodiazepines." | 4.91 | Melatonin for pre- and postoperative anxiety in adults. ( Gögenur, I; Halladin, NL; Hansen, MV; Møller, AM; Rosenberg, J, 2015) |
| " Of the 10 studies that evaluated parents' anxiety, most did not find parental presence to be more effective than no parental presence, midazolam, or parental presence plus midazolam." | 4.85 | An evidence-based review of parental presence during anesthesia induction and parent/child anxiety. ( Chundamala, J; Kemp, SM; Wright, JG, 2009) |
| "Oral midazolam premedication in children was found to reduce the anxiety associated with separation from parents/guardians, and with induction of anesthesia." | 4.83 | Evidence-based clinical update: does premedication with oral midazolam lead to improved behavioural outcomes in children? ( Cox, RG; Crowe, MJ; Ewen, A; Nemish, U, 2006) |
| "Based on the findings from this cohort, high preinduction anxiety does not appear to be associated with NBCs postoperatively in children premedicated with clonidine or midazolam." | 4.31 | Preoperative anxiety level is not associated with postoperative negative behavioral changes in premedicated children. ( Brorsson, C; Haney, M; Hultin, M; Johansson, G; Winsö, O; Zickerman, C, 2023) |
| "Oral midazolam is commonly administered to reduce anxiety in children presenting for medical procedures or surgery." | 4.31 | Residual unabsorbed midazolam: a case report. ( Baboolal, HA; Gulati, A, 2023) |
| " In the second step of research, we applied a midazolam (benzodiazepine) treatment to examine the effect of anxiety on empathy-like behavior." | 4.31 | The ameliorative effect of midazolam on empathy-like behavior in old rats. ( Akkaya, EC; Gumus, H; Hosgorler, F; Ilgin, R; Kizildag, S; Koc, B; Uysal, N, 2023) |
| " This prospective observational study included 638 pediatric American Society of Anesthesiologists I-II patients who underwent ambulatory pediatric surgery, grouped into four preoperative preparation groups: NADA (not premedicated), MDZ (premedicated with midazolam), PPIA (parental presence during induction of anesthesia), and PPIA + MDZ." | 4.12 | Parental Presence during Induction of Anesthesia Improves Compliance of the Child and Reduces Emergence Delirium. ( Alonso Calderón, J; Gajate Martin, L; Gil Mayo, D; Gomez Rojo, M; Hernández Oliveros, F; Sanabria Carretero, P, 2022) |
| "Patients with IBS who underwent elective colonoscopy procedures expressed higher pre-procedural anxiety scores, required more propofol consumption, and experienced more disruptive movements compared with controls." | 3.88 | Ambulatory colonoscopy under sedoanalgesia in adult patients with and without irritable bowel syndrome: A prospective, cross-sectional, and double-blind comparison. ( Araz, C; Çelebi, A; Tuncalı, B, 2018) |
| "In our practice, patients undergoing bilateral cataract surgery complain of more significant pain after the 2nd eye surgery." | 3.85 | [Prevalence and causes of pain after cataract surgery: Comparison of 1st and 2nd eyes]. ( Amzallag, T; Gayadine-Harricham, Y, 2017) |
| " The primary objective of the current study was to assess differences in blood pressure and heart rate before and after induction of anesthesia between patients on chronic amphetamine or methylphenidate therapy who receive their normal dose preoperatively compared to patients in whom the prescribed medication was withheld." | 3.85 | Hemodynamic profile and behavioral characteristics during induction of anesthesia in pediatric patients with attention deficit hyperactivity disorder. ( Cartabuke, RS; Rice, J; Tobias, JD; Tumin, D, 2017) |
| "The World Health Organization recommends that anxiety, depression, agitation and delirium at end of life should be treated with drugs such as lorazepam, diazepam, midazolam and haloperidol." | 3.83 | Look again at psychedelic drugs. ( Cameron, R, 2016) |
| "The aim of this study was to examine the effects of benzodiazepine (midazolam) administration on rat conditioned fear responses and on local brain activity (c-Fos and CRF expressions) of low- (LR) and high- (HR)anxiety rats after the first and second contextual fear test sessions." | 3.81 | Midazolam treatment before re-exposure to contextual fear reduces freezing behavior and amygdala activity differentially in high- and low-anxiety rats. ( Krząścik, P; Lehner, M; Płaźnik, A; Skórzewska, A; Sobolewska, A; Turzyńska, D; Wisłowska-Stanek, A, 2015) |
| "Midazolam requires BZD-sensitive α1- and α2-containing GABAA receptors in order to escalate aggression and α2- and α3-containing receptors to reduce social anxiety-like behavior." | 3.81 | α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice. ( Chen, Y; Chu, A; DeBold, JF; Hwa, LS; Miczek, KA; Newman, EL; Rudolph, U; Smith, KS; Takahashi, A, 2015) |
| " Significant difference was observed between EA and the control group in many aspects, such as sex, age, ASA classify, smoking history, history of cerebrovascular disease, preoperative anxiety, the use of midazolam, anesthesia means, postoperative pain, postoperative analgesia, presence of a tracheal tube, and presence of a urinary catheter." | 3.81 | [Analysis of risk factors for emergence agitation in adults undergoing general anesthesia for nasal surgery]. ( Liu, Z, 2015) |
| "Patients who received both midazolam and morphine experienced a more rapid decline in anxiety and used less opioid medication than those receiving morphine alone." | 3.80 | A placebo-controlled trial of midazolam as an adjunct to morphine patient-controlled analgesia after spinal surgery. ( Berbaum, ML; Day, MA; Mangieri, EA; Rich, MA; Thorn, BE, 2014) |
| " The present study focused on the long-term effects of developmentally altered allopregnanolone (AlloP) levels on anxiety-like behavior in adulthood." | 3.78 | Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats. ( Darbra, S; Pallarès, M, 2012) |
| "To compare the effectiveness of oral midazolam and chloral hydrate on anxiety and sedation at various stages of pre-operative period in congenital heart surgery patients." | 3.78 | Effectiveness of premedication at the time of separation from parent and mask induction in paediatric patients coming for congenital heart disease surgery. ( Akhtar, I; Hamid, M; Khan, MA; Khatri, A, 2012) |
| "5 mg/kg oral midazolam at 20-40 min before induction of anesthesia." | 3.74 | Effects of age and emotionality on the effectiveness of midazolam administered preoperatively to children. ( Anderson, GM; Kain, ZN; MacLaren, J; Mayes, LC; McClain, BC; Saadat, H; Wang, SM, 2007) |
| " We hypothesized that chrysin decreases anxiety via interaction with the GABA(A) receptor in laboratory rats as measured by elevated plus-maze (EPM), corticosterone, and catecholamine assays." | 3.74 | Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat. ( Brown, E'; Ceremuga, TE; Hurd, NS; McCall, S, 2007) |
| " Specifically, we examined the relationship between anxiety and motor activity after bilateral intra-amygdala or intra-hippocampal microinjections of the nonselective full benzodiazepine receptor agonist midazolam in C57BL/6 mice." | 3.73 | Localized injections of midazolam into the amygdala and hippocampus induce differential changes in anxiolytic-like motor activity in mice. ( Heldt, SA; Ressler, KJ, 2006) |
| " At the initial surgery, children were assigned (no parental intervention) to receive oral midazolam (n = 13), or parental presence during the induction of anesthesia (PPIA, n = 27), or PPIA + midazolam (n = 10) or no intervention (n = 33)." | 3.72 | Parental intervention choices for children undergoing repeated surgeries. ( Caldwell-Andrews, AA; Kain, ZN; Krivutza, DM; Mayes, LC; Wang, SM; Weinberg, ME, 2003) |
| "The contribution of GABAergic mechanisms to rat emotional behavior in two animal models of anxiety (open field test of neophobia and aversively conditioned freezing reaction), was confirmed by pharmacological analysis, using anxiolytic (midazolam) and anxiogenic (picrotoxin) compounds." | 3.72 | Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis. ( Bidziński, A; Członkowska, AI; Lehner, M; Maciejak, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J; Turzyńska, D; Wisłowska, A; Zienowicz, M, 2003) |
| "The effects of intra-amygdala injection of midazolam (20 nmol) and 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT; 8 and 16 nmol) were investigated in rats submitted to the elevated T-maze, a new animal model of anxiety." | 3.70 | Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino)tetralin in the elevated T-maze. ( Graeff, FG; Viana, MB; Zangrossi, H, 1999) |
| " The opiate antagonist naloxone (1 mg/kg and 10 mg/kg) neither blocked this open arm-induced antinociception (OAIA) nor modified indices of anxiety in EPM." | 3.70 | Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam. ( Canto-de-Souza, A; da-Costa, M; Fornari, RV; Graeff, FG; Nunes-de-Souza, RL; Pelá, IR, 2000) |
| "Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'." | 3.69 | The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines. ( Pesold, C; Treit, D, 1995) |
| "Microinfusions of a benzodiazepine anxiolytic (midazolam) into the septum or the amygdala suppressed different fear reactions in two tests of rat "anxiety"." | 3.69 | The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines. ( Pesold, C; Treit, D, 1994) |
| "The object of this study was to grade the response of patients undergoing a variety of dental procedures with the aid of intravenous midazolam sedation in general dental practice and to explore any relationships between the patients preoperative anxiety assessment and the clinician's assessment of co-operation whilst under sedation." | 3.69 | Response to intravenous midazolam sedation in general dental practice. ( Ellis, S, 1996) |
| "In order to investigate the role of the dorsal periaqueductal grey (DPAG) area in the anxiolytic effect of benzodiazepines male Wistar rats (N = 10), weighing 200-250 g at the time of surgery, were microinjected into this structure with midazolam (80 nmol) and submitted to the elevated plus-maze, an ethologically based model of anxiety." | 3.68 | Anxiolytic effect of midazolam microinjected into the dorsal periaqueductal grey area of rats. ( De Aguiar, JC; Graeff, FG; Guimarães, FS; Russo, AS, 1991) |
| "Midazolam 0." | 3.11 | Serum concentration of oral midazolam as pediatric preanesthetic medication and factors related to the sedation level. ( Atsuda, K; Kawabata, M; Komatsu, T; Matsuda, H; Okamoto, H; Sakanoue, K; Takenaka, J, 2022) |
| "Melatonin has been proposed as a premedication alternative to midazolam, preceding anaesthesia induction." | 2.82 | Melatonin versus midazolam premedication in children undergoing surgery: A pilot study. ( Crisafi, C; D'Angelo, G; Gitto, E; Impellizzeri, P; Manti, S; Marseglia, L; Montalto, AS; Reiter, RJ; Romeo, C, 2016) |
| "Midazolam is a short-acting water-soluble benzodiazepine with a rapid onset of action and short half-life." | 2.82 | A randomised, double-blind controlled trial of intranasal midazolam for the palliation of dyspnoea in patients with life-limiting disease. ( Allan, S; Flatley, C; Gibbons, K; Hardy, J; Pinkerton, E; Randall, C, 2016) |
| " Median dosing was 0." | 2.80 | A randomized, double-blind pilot study of dexmedetomidine versus midazolam for intensive care unit sedation: patient recall of their experiences and short-term psychological outcomes. ( Fish, DN; Kiser, TH; Lavelle, JC; MacLaren, R; Malkoski, SP; Mueller, SW; Preslaski, CR, 2015) |
| "Forty-five breast cancer patients were randomized into three groups: Group I--chemotherapy, control, Group II--midazolam+chemotherapy, and Group III--propofol+chemotherapy." | 2.71 | Effect of sedation with midazolam or propofol on patient's comfort during cancer chemotherapy infusion: a prospective, randomized, double-blind study in breast cancer patients. ( Argun, G; Baran, O; Dikmen Mentes, S; Ertunc, FN; Unsal, D, 2005) |
| "001) but times from dosing to discharge (medians 105 and 110 minutes) were similar." | 2.70 | Sedation for children requiring wound repair: a randomised controlled double blind comparison of oral midazolam and oral ketamine. ( Kendall, JM; Younge, PA, 2001) |
| " Supplemental dosing was administered to children who were judged inadequately sedated 30 minutes after the initial medication." | 2.69 | Chloral hydrate versus midazolam for sedation of children for neuroimaging: a randomized clinical trial. ( D'Agostino, J; Terndrup, TE, 2000) |
| " The control group and the test groups were comparable with regard to biological data, duration of operation, applied dosage of local anaesthetics and actual anxiety before operation." | 2.68 | [Analgesia-sedation for maxillo-facial surgery with midazolam-pentazocine and miazolam-ketamine. Clinical double-blind study of anxiety, analgesia, sedation and amnesia]. ( Daubländer, M; Dick, W; Lipp, M; Sebastian, M, 1995) |
| "Midazolam was administered during the procedure by staff who were blinded to the state/trait anxiety scores and the type of consent the patient had received." | 2.68 | Effect of informed consent on anxiety in patients undergoing diagnostic electrophysiology studies. ( Goldberger, JJ; Kadish, AH; Kruse, J; Parker, MA, 1997) |
| "Fentanyl was required more often in MF group: median 3." | 2.67 | Intramuscular dexmedetomidine premedication--an alternative to midazolam-fentanyl-combination in elective hysterectomy? ( Jaakola, ML; Kallio, A; Kanto, J; Scheinin, H, 1994) |
| "Midazolam was found to be the drug of preference for the majority of patients." | 2.67 | Midazolam versus fentanyl as premedication for painful procedures in children with cancer. ( Conner, K; Dickson, N; Luzins, J; McGorray, S; Reilly, K; Sandler, ES; Weyman, C, 1992) |
| "Midazolam was found to be more effective than ketobemidone in reducing anxiety among more tense patients--those with a VAS grading before premedication of 2 or more (P less than 0." | 2.67 | Premedication before elective breast surgery, a comparison between ketobemidone and midazolam. ( Andersson, L; Askergren, J; Davidson, S; Jakobsson, J; Nilsson, A, 1991) |
| " However, the results indicate that levels of anxiolysis and sedation were significantly associated with midazolam dosage (p less than 0." | 2.67 | Paradoxical reactions to rectal midazolam as premedication in children. ( Hartshorne, J; Joubert, JJ; Roelofse, JA; Stegmann, DH, 1990) |
| "Midazolam is a short-acting benzodiazepine with anxiolytic, hypnotic, and antegrade amnestic effects." | 2.67 | The effect of oral midazolam on anxiety of preschool children during laceration repair. ( Bonadio, WA; Glaeser, PW; Hennes, HM; Losek, JD; Smith, DS; Wagner, V; Walsh-Kelly, CM, 1990) |
| "Midazolam was superior to temazepam regarding anxiolysis, sedation and amnesia, but temazepam was superior to placebo." | 2.66 | Benzodiazepine premedication in minor day-case surgery: comparison of oral midazolam and temazepam with placebo. ( Hargreaves, J, 1988) |
| "Midazolam 0." | 2.66 | Intramuscular midazolam premedication in small children. A comparison with papaveretum and hyoscine. ( Hatch, DJ; Taylor, MB; Vine, PR, 1986) |
| " We concluded that there are no major differences between the three drugs in the dosage used." | 2.66 | Diazepam, flunitrazepam and midazolam for elective endoscopy--a comparative study. ( Badran, I; Hunjul, N; Sbeih, Z; Takrouri, MS; Toukan, A, 1988) |
| "Chloral hydrate was significantly less palatable than midazolam." | 2.66 | Comparison of chloral hydrate and midazolam by mouth as premedicants in children undergoing otolaryngological surgery. ( Klemola, UM; Lindgren, L; Saarnivaara, L, 1988) |
| "Midazolam is an efficacious, safe premedicant in relatively healthy patients." | 2.65 | Premedication with intramuscular midazolam: a prospective randomized double-blind controlled study. ( Reves, JG; Vinik, HR; Wright, D, 1982) |
| " The use of MAD even gives as better bioavailability of drugs." | 2.58 | Intranasal drug administration for procedural sedation in children admitted to pediatric Emergency Room. ( Chiaretti, A; Fabrizio, GC; Fantacci, C; Ferrara, P; Franceschi, F, 2018) |
| "Midazolam is a good premedicant for general or regional anesthesia." | 2.37 | Use of midazolam hydrochloride in anesthesia. ( Khanderia, U; Pandit, SK, 1987) |
| " The mean dosage of propofol in group A was significantly higher (62." | 1.56 | Pre-endoscopic tachycardia predicts increased sedation dose and lower adenoma detection rate in patients undergoing endoscopic procedures: a case control study. ( Ahmad, HS; Baker, FA; Kadah, A; Khoury, T; Mahajnah, M; Mahamid, M; Mari, A; Pellicano, R; Sbeit, W, 2020) |
| "While post-traumatic stress disorder (PTSD) can develop after exposure to severe traumatic events, data have shown that individuals with high sensation-seeking personality traits are less prone to developing PTSD." | 1.56 | Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats. ( Chacho, NM; Dravid, SM; Pipitone, L; Stairs, DJ; Wunsch, C, 2020) |
| "Evaluate adverse events associated with oral midazolam as a perioperative anxiolytic during dermatologic surgery and assess whether an enhanced monitoring approach is associated with an increased detection rate." | 1.56 | Safety of Oral Midazolam as a Perioperative Anxiolytic for Outpatient Dermatologic Procedures. ( Arpey, CJ; Baum, CL; Bezalel, SA; Brewer, JD; Otley, CC; Roenigk, RK, 2020) |
| " The primary outcome measures were adverse events and failed laceration repair." | 1.51 | Safety and effectiveness of intranasal midazolam and fentanyl used in combination in the pediatric emergency department. ( Cosgrove, P; Kienstra, AJ; Ryan, PM; Vezzetti, R; Wilkinson, M, 2019) |
| " There are no previous studies of validated anxiety scores with pharmacokinetic data to support optimal procedure timing." | 1.46 | Evaluating Clinical Effectiveness and Pharmacokinetic Profile of Atomized Intranasal Midazolam in Children Undergoing Laceration Repair. ( Adelgais, K; Bourne, D; Brent, A; Brou, L; Galinkin, J; Mellion, SA; Wathen, J, 2017) |
| "At the end of life of cancer patients, sedation is sometimes needed, in order to palliate unbearable symptoms that other treatments fail to relieve." | 1.46 | [Towards a better use of midazolam in end of life: A survey in a department of medical oncology]. ( Beneton, A; Brosse, C; Magné, N; Morisson, S; Pacaut, C; Poenou, G; Vallard, A, 2017) |
| "Heat facial hyperalgesia was assessed on day 6 after the inoculation, and on this time point rats were submitted to the elevated plus maze and the light-dark transition tests." | 1.43 | Evaluation of heat hyperalgesia and anxiety like-behaviors in a rat model of orofacial cancer. ( Chichorro, JG; Dos Reis, RC; Gambeta, E; Kopruszinski, CM; Zanoveli, JM, 2016) |
| "Post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder that may develop after an individual has experienced or witnessed a severe traumatic event." | 1.40 | Midazolam ameliorates the behavior deficits of a rat posttraumatic stress disorder model through dual 18 kDa translocator protein and central benzodiazepine receptor and neurosteroidogenesis. ( Fang, WW; Guo, WZ; Li, BW; Li, YF; Liu, J; Liu, Y; Miao, YL; Shi, WZ; Wu, W, 2014) |
| "Anxiety disorders and substance abuse, including benzodiazepine use disorder, frequently occur together." | 1.39 | Genetic markers of a Munc13 protein family member, BAIAP3, are gender specifically associated with anxiety and benzodiazepine abuse in mice and humans. ( Augustin, I; Begemann, M; Brose, N; Ehrenreich, H; Gurvich, A; Ju, A; Man, KN; Müller-Ribbe, K; Papiol, S; Ronnenberg, A; Shin, Y; Stepniak, B; Tantra, M; Wojcik, SM, 2013) |
| "When myristicin was combined with midazolam, an antagonist-like effect similar to the flumazenil and myristicin combination was exhibited by a decrease in anxiolysis compared with the midazolam-only group." | 1.37 | Evaluation of the anxiolytic properties of myristicin, a component of nutmeg, in the male Sprague-Dawley rat. ( Ceremuga, TE; Godwin, S; Hitchcock, G; Johnson, M; Jones, W; Leiter, E; McCall, S; Sedgwick, W, 2011) |
| "Conditions precipitating acute respiratory failure (ARF) were classified into two groups: type 1 (38 episodes) and type 2 (78 episodes)." | 1.35 | Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study. ( Concha, A; Díaz, JJ; Los Arcos, M; Mayordomo-Colunga, J; Medina, A; Menéndez, S; Rey, C, 2009) |
| "Luteolin is a major component of the essential oil lemon balm." | 1.35 | Investigation of the anxiolytic effects of luteolin, a lemon balm flavonoid in the male Sprague-Dawley rat. ( Ceremuga, TE; Duncan, R; Jones, P; McCall, S; Moe, N; Raines, T, 2009) |
| " Optimal INM dosing strategies for uncooperative children undergoing TTE are largely unknown, including second-dose INM strategies, introduced to maximize the potential for successful sedation and minimize risk." | 1.35 | Minimal sedation second dose strategy with intranasal midazolam in an outpatient pediatric echocardiographic setting. ( DeGroff, CG; Lazol, JP, 2009) |
| "Diagnosis of neurocardiogenic syncope (NCS) was made by previous episodes of fainting revealed at that point." | 1.35 | [Case of neurocardiogenic syncope with asystole during insertion of epidural catheter]. ( Ito, H; Kanazawa, M; Tajiri, O; Tateda, T; Yago, Y, 2009) |
| "L-theanine is a major component of green tea, which has traditionally been used as an herbal remedy in the treatment of many medical conditions, including anxiety." | 1.35 | Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat. ( Adams, C; Ceremuga, TE; Heese, T; Jenkinson, J; Love, C; McCall, S; Milam, R; Perkins, L, 2009) |
| "Linalool is a major component of the essential oil of lavender." | 1.35 | Investigation of the anxiolytic effects of linalool, a lavender extract, in the male Sprague-Dawley rat. ( Bracken, S; Ceremuga, TE; Cline, M; Flores, J; McCall, S; Taylor, JE, 2008) |
| " Demographic data, time in ED, and dosage of each medication given were abstracted." | 1.35 | Inadequate provision of postintubation anxiolysis and analgesia in the ED. ( Bonomo, JB; Butler, AS; Lindsell, CJ; Venkat, A, 2008) |
| "Management of airway foreign bodies must be undertaken in specialized units with experienced staff and known protocols." | 1.32 | How we do it: management of tracheobronchial foreign bodies in children. ( Babin, E; Bigeon, JY; Doppia, MA; Edy, E; Sigston, E, 2004) |
| "Oral midazolam is a short-acting benzodiazepine that can ameliorate procedure-related anxiety." | 1.31 | Anxiolysis with oral midazolam in pediatric patients undergoing dermatologic surgical procedures. ( Nguyen, TH; Otley, CC; Phillips, PK, 2001) |
| " The dosage needed to initiate and maintain sedation must be adjusted to body weight, degree of sedation desired, and concomitant medications, as well as to underlying health and cardiovascular status." | 1.30 | Sedation with intravenous midazolam in the pediatric intensive care unit. ( Notterman, DA, 1997) |
| " To determine whether there are parallel or divergent rates of elimination of the two drugs between individuals, the pharmacokinetic profiles of midazolam and flumazenil were studied simultaneously in 12 adult male volunteers." | 1.29 | Midazolam and flumazenil pharmacokinetics and pharmacodynamics following simultaneous administration to human volunteers. ( Gin, T; Oh, TE; Short, TG; Tam, YH; Tan, P; Young, KK, 1994) |
| "Midazolam 1 mg was effective in the males (from 45% to 10%) and tended to allay patients' pain feeling in the females (from 40% to 23%)." | 1.29 | [The effects of small dose midazolam in patients to reduce the uncomfortable feeling during epidural block procedure]. ( Kasaba, T, 1994) |
| "Midazolam 2." | 1.28 | [The effects of pentazocine, diazepam and midazolam in patients to reduce the uncomfortable feeling during epidural block procedure]. ( Kasaba, T, 1992) |
| "Midazolam hydrochloride is an ultra-short acting benzodiazepine recently approved by the Food and Drug Administration for anesthesia induction and preoperative sedation." | 1.28 | Precipitation of benzodiazepine withdrawal following sudden discontinuation of midazolam. ( Finley, PR; Nolan, PE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (7.23) | 18.7374 |
| 1990's | 86 (24.86) | 18.2507 |
| 2000's | 109 (31.50) | 29.6817 |
| 2010's | 101 (29.19) | 24.3611 |
| 2020's | 25 (7.23) | 2.80 |
| Authors | Studies |
|---|---|
| Evren Sahin, K | 1 |
| Karkiner, A | 1 |
| Choi, YJ | 1 |
| Park, EJ | 1 |
| Lee, YM | 1 |
| Kim, SC | 1 |
| Kang, B | 1 |
| Lee, KJ | 1 |
| Jang, HJ | 1 |
| Lee, EH | 1 |
| Kim, JY | 1 |
| Choi, SY | 1 |
| Jin Kim, H | 1 |
| Kang, Y | 1 |
| Choe, BH | 1 |
| Lee, J | 1 |
| Yi, DY | 1 |
| Matsuda, H | 1 |
| Takenaka, J | 1 |
| Kawabata, M | 1 |
| Komatsu, T | 1 |
| Sakanoue, K | 1 |
| Atsuda, K | 1 |
| Okamoto, H | 1 |
| Nathan, JE | 1 |
| Zickerman, C | 1 |
| Brorsson, C | 1 |
| Hultin, M | 2 |
| Johansson, G | 1 |
| Winsö, O | 1 |
| Haney, M | 1 |
| Baboolal, HA | 1 |
| Gulati, A | 1 |
| Hosgorler, F | 1 |
| Akkaya, EC | 1 |
| Ilgin, R | 1 |
| Koc, B | 1 |
| Kizildag, S | 1 |
| Gumus, H | 1 |
| Uysal, N | 1 |
| Hauge, MS | 1 |
| Willumsen, T | 1 |
| Stora, B | 1 |
| Brignardello-Petersen, R | 2 |
| Schmid, W | 1 |
| Marhofer, P | 1 |
| Ohmann, S | 1 |
| Kimberger, O | 2 |
| Marhofer, D | 1 |
| Triffterer, L | 1 |
| Zhang, C | 1 |
| Bianchi de Moraes, M | 1 |
| Barbier, WS | 1 |
| Raldi, FV | 1 |
| Nascimento, RD | 1 |
| Murilo Dos Santos, L | 1 |
| Loureiro Sato, FR | 1 |
| Mari, A | 1 |
| Khoury, T | 1 |
| Mahajnah, M | 1 |
| Kadah, A | 1 |
| Ahmad, HS | 1 |
| Baker, FA | 1 |
| Pellicano, R | 1 |
| Mahamid, M | 1 |
| Sbeit, W | 1 |
| Marquez, JL | 1 |
| Wang, E | 1 |
| Rodriguez, ST | 1 |
| O'Connell, C | 1 |
| Munshey, F | 1 |
| Darling, C | 1 |
| Tsui, B | 1 |
| Caruso, J | 1 |
| Caruso, TJ | 1 |
| Stairs, DJ | 1 |
| Chacho, NM | 1 |
| Wunsch, C | 1 |
| Pipitone, L | 1 |
| Dravid, SM | 1 |
| Babaei, S | 1 |
| Fatahi Babani, S | 1 |
| Fakhri, M | 1 |
| Shahsavari, S | 1 |
| Parviz, A | 1 |
| Karbasfrushan, A | 1 |
| Etemadi, M | 1 |
| Shirzadi, M | 1 |
| Bezalel, SA | 1 |
| Brewer, JD | 1 |
| Baum, CL | 1 |
| Arpey, CJ | 1 |
| Roenigk, RK | 1 |
| Otley, CC | 2 |
| Sakızcı Uyar, B | 1 |
| Polat, R | 2 |
| Bolat, M | 1 |
| Donmez, A | 1 |
| Heard, JA | 1 |
| Zacarias, AAG | 1 |
| Lawrence, AT | 1 |
| Stoicea, N | 1 |
| Palettas, M | 1 |
| Fiorda-Diaz, J | 1 |
| Guertin, MG | 1 |
| Tandon, A | 1 |
| Lowery, DS | 1 |
| Madsen, BK | 1 |
| Zetner, D | 1 |
| Møller, AM | 2 |
| Rosenberg, J | 2 |
| Conway, A | 2 |
| Chang, K | 1 |
| Mafeld, S | 1 |
| Sutherland, J | 1 |
| Gil Mayo, D | 1 |
| Sanabria Carretero, P | 1 |
| Gajate Martin, L | 1 |
| Alonso Calderón, J | 1 |
| Hernández Oliveros, F | 1 |
| Gomez Rojo, M | 1 |
| Tharion, JG | 1 |
| Kale, S | 1 |
| Bromfalk, Å | 1 |
| Myrberg, T | 1 |
| Walldén, J | 1 |
| Engström, Å | 1 |
| Burns-Nader, S | 1 |
| Joe, L | 1 |
| Pinion, K | 1 |
| Impellizzeri, P | 2 |
| Vinci, E | 1 |
| Gugliandolo, MC | 1 |
| Cuzzocrea, F | 1 |
| Larcan, R | 1 |
| Russo, T | 1 |
| Gravina, MR | 1 |
| Arena, S | 1 |
| D'Angelo, G | 2 |
| Gitto, E | 2 |
| Montalto, AS | 2 |
| Alibrandi, A | 1 |
| Marseglia, L | 2 |
| Romeo, C | 2 |
| Gayadine-Harricham, Y | 1 |
| Amzallag, T | 1 |
| Sola, C | 1 |
| Lefauconnier, A | 1 |
| Bringuier, S | 1 |
| Raux, O | 1 |
| Capdevila, X | 1 |
| Dadure, C | 1 |
| Amini, S | 1 |
| Peiman, S | 1 |
| Khatuni, M | 1 |
| Ghalamkari, M | 1 |
| Rahimi, B | 1 |
| Castle, C | 1 |
| Gray, A | 1 |
| Neehoff, S | 1 |
| Glue, P | 1 |
| Mellion, SA | 1 |
| Bourne, D | 1 |
| Brou, L | 1 |
| Brent, A | 1 |
| Adelgais, K | 1 |
| Galinkin, J | 1 |
| Wathen, J | 1 |
| Beneton, A | 1 |
| Vallard, A | 1 |
| Brosse, C | 1 |
| Poenou, G | 1 |
| Pacaut, C | 1 |
| Magné, N | 1 |
| Morisson, S | 1 |
| Wang, TJ | 1 |
| Liu, Y | 2 |
| Guan, M | 1 |
| Fantacci, C | 1 |
| Fabrizio, GC | 1 |
| Ferrara, P | 1 |
| Franceschi, F | 1 |
| Chiaretti, A | 2 |
| Wangüemert Pérez, AL | 1 |
| González Expósito, H | 1 |
| Pascual Fernández, L | 1 |
| Nunes, SL | 1 |
| Forsberg, S | 1 |
| Blomqvist, H | 1 |
| Berggren, L | 1 |
| Sörberg, M | 1 |
| Sarapohja, T | 1 |
| Wickerts, CJ | 1 |
| Tuncalı, B | 1 |
| Araz, C | 1 |
| Çelebi, A | 1 |
| Liu, PP | 1 |
| Sun, Y | 1 |
| Wu, C | 1 |
| Xu, WH | 1 |
| Zhang, RD | 1 |
| Zheng, JJ | 1 |
| Huang, Y | 1 |
| Chen, YQ | 1 |
| Zhang, MZ | 1 |
| Wu, JZ | 1 |
| Nasr, VG | 1 |
| DiNardo, JA | 1 |
| Ryan, PM | 1 |
| Kienstra, AJ | 1 |
| Cosgrove, P | 1 |
| Vezzetti, R | 1 |
| Wilkinson, M | 1 |
| Jeon, S | 1 |
| Lee, HJ | 1 |
| Do, W | 1 |
| Kim, HK | 1 |
| Kwon, JY | 1 |
| Hwang, BY | 1 |
| Yun, J | 1 |
| Acuña, LR | 1 |
| Marchette, RCN | 1 |
| Granzotto, N | 1 |
| Dias, PG | 1 |
| Corvino, ME | 1 |
| Mazur, FG | 1 |
| Corrêa, FJ | 1 |
| Izídio, GS | 2 |
| Park, SW | 1 |
| Choi, JH | 1 |
| Kim, HT | 1 |
| Cho, YH | 1 |
| Hanna, AH | 1 |
| Ramsingh, D | 1 |
| Sullivan-Lewis, W | 1 |
| Cano, S | 1 |
| Leiter, P | 1 |
| Wallace, D | 1 |
| Andrews, G | 1 |
| Austin, B | 1 |
| Applegate, RL | 1 |
| Stewart, B | 1 |
| Cazzell, MA | 1 |
| Pearcy, T | 1 |
| Dellovo, AG | 1 |
| Souza, LMA | 1 |
| de Oliveira, JS | 1 |
| Amorim, KS | 1 |
| Groppo, FC | 1 |
| Salloum, NC | 1 |
| Fava, M | 1 |
| Freeman, MP | 1 |
| Flynn, M | 1 |
| Hoeppner, B | 1 |
| Hock, RS | 1 |
| Cusin, C | 1 |
| Iosifescu, DV | 1 |
| Trivedi, MH | 1 |
| Sanacora, G | 1 |
| Mathew, SJ | 1 |
| Debattista, C | 1 |
| Ionescu, DF | 1 |
| Papakostas, GI | 1 |
| Zhong, L | 1 |
| Shen, K | 1 |
| Zhai, S | 1 |
| Chen, T | 2 |
| Tao, Q | 1 |
| Chen, L | 1 |
| Tao, Y | 1 |
| Qiu, L | 1 |
| Akhlaghi, N | 1 |
| Payandemehr, P | 1 |
| Yaseri, M | 1 |
| Akhlaghi, AA | 1 |
| Abdolrazaghnejad, A | 1 |
| Williams, JM | 1 |
| Schuman, S | 1 |
| Regen, R | 1 |
| Berg, A | 1 |
| Stuart, L | 1 |
| Raju, J | 1 |
| Mabry, W | 1 |
| Kink, RJ | 1 |
| Du, Z | 1 |
| Zhang, XY | 1 |
| Qu, SQ | 1 |
| Song, ZB | 1 |
| Wei, SW | 1 |
| Xiang, Z | 1 |
| Guo, QL | 1 |
| Baetzel, A | 1 |
| Brown, DJ | 1 |
| Koppera, P | 1 |
| Rentz, A | 1 |
| Thompson, A | 1 |
| Christensen, R | 1 |
| Strauss, CV | 1 |
| Vicente, MA | 1 |
| Zangrossi, H | 3 |
| Steifelhagen, P | 1 |
| Wojcik, SM | 1 |
| Tantra, M | 1 |
| Stepniak, B | 1 |
| Man, KN | 1 |
| Müller-Ribbe, K | 1 |
| Begemann, M | 1 |
| Ju, A | 1 |
| Papiol, S | 1 |
| Ronnenberg, A | 1 |
| Gurvich, A | 1 |
| Shin, Y | 1 |
| Augustin, I | 1 |
| Brose, N | 1 |
| Ehrenreich, H | 1 |
| Nguyen, NQ | 1 |
| Toscano, L | 1 |
| Lawrence, M | 1 |
| Moore, J | 1 |
| Holloway, RH | 1 |
| Bartholomeusz, D | 1 |
| Lidums, I | 1 |
| Tam, W | 1 |
| Roberts-Thomson, IC | 1 |
| Mahesh, VN | 1 |
| Debreceni, TL | 1 |
| Schoeman, MN | 1 |
| Senses, E | 1 |
| Apan, A | 1 |
| Köse, EA | 1 |
| Oz, G | 1 |
| Rezaki, H | 1 |
| Giroud, M | 1 |
| Sellier, E | 1 |
| Laval, G | 1 |
| Maldonado, NM | 1 |
| Espejo, PJ | 1 |
| Martijena, ID | 1 |
| Molina, VA | 2 |
| MacLaren, R | 1 |
| Preslaski, CR | 1 |
| Mueller, SW | 1 |
| Kiser, TH | 1 |
| Fish, DN | 1 |
| Lavelle, JC | 1 |
| Malkoski, SP | 1 |
| Kerimoglu, B | 1 |
| Neuman, A | 1 |
| Paul, J | 1 |
| Stefanov, DG | 1 |
| Twersky, R | 1 |
| Mitra, S | 1 |
| Kazal, S | 1 |
| Anand, LK | 1 |
| Day, MA | 1 |
| Rich, MA | 1 |
| Thorn, BE | 1 |
| Berbaum, ML | 1 |
| Mangieri, EA | 1 |
| Miao, YL | 1 |
| Guo, WZ | 1 |
| Shi, WZ | 1 |
| Fang, WW | 1 |
| Liu, J | 1 |
| Li, BW | 1 |
| Wu, W | 1 |
| Li, YF | 1 |
| Seiden, SC | 1 |
| McMullan, S | 1 |
| Sequera-Ramos, L | 1 |
| De Oliveira, GS | 1 |
| Roth, A | 1 |
| Rosenblatt, A | 1 |
| Jesdale, BM | 1 |
| Suresh, S | 2 |
| Saito, VM | 1 |
| Brandão, ML | 7 |
| Ramanadham, SR | 1 |
| Costa, CR | 1 |
| Narasimhan, K | 1 |
| Coleman, JE | 1 |
| Rohrich, RJ | 1 |
| Skórzewska, A | 2 |
| Lehner, M | 3 |
| Wisłowska-Stanek, A | 2 |
| Turzyńska, D | 3 |
| Sobolewska, A | 2 |
| Krząścik, P | 2 |
| Płaźnik, A | 7 |
| Pasin, L | 1 |
| Febres, D | 1 |
| Testa, V | 1 |
| Frati, E | 1 |
| Borghi, G | 1 |
| Landoni, G | 1 |
| Zangrillo, A | 1 |
| Chen, Q | 1 |
| Wang, L | 1 |
| Ge, L | 1 |
| Gao, Y | 1 |
| Wang, H | 2 |
| Hansen, MV | 1 |
| Halladin, NL | 1 |
| Gögenur, I | 1 |
| Ceremuga, TE | 6 |
| Valdivieso, D | 1 |
| Kenner, C | 1 |
| Lucia, A | 1 |
| Lathrop, K | 1 |
| Stailey, O | 1 |
| Bailey, H | 1 |
| Criss, J | 1 |
| Linton, J | 1 |
| Fried, J | 1 |
| Taylor, A | 1 |
| Padron, G | 1 |
| Johnson, AD | 1 |
| Plum, AW | 1 |
| Harris, TM | 1 |
| Sakae, DY | 1 |
| Sakae, TM | 1 |
| Paschoalini, MA | 1 |
| Faria, MS | 2 |
| Bayer, LL | 1 |
| Edelman, AB | 1 |
| Fu, R | 1 |
| Lambert, WE | 1 |
| Nichols, MD | 1 |
| Bednarek, PH | 1 |
| Miller, K | 1 |
| Jensen, JT | 1 |
| Han, G | 1 |
| Li, L | 1 |
| Tian, Y | 1 |
| Xue, H | 1 |
| Zhao, P | 1 |
| Newman, EL | 1 |
| Smith, KS | 1 |
| Takahashi, A | 1 |
| Chu, A | 1 |
| Hwa, LS | 1 |
| Chen, Y | 1 |
| DeBold, JF | 1 |
| Rudolph, U | 1 |
| Miczek, KA | 2 |
| Manti, S | 1 |
| Crisafi, C | 1 |
| Reiter, RJ | 1 |
| Wenzel, M | 1 |
| Schulze Schwering, M | 1 |
| Hardy, J | 1 |
| Randall, C | 1 |
| Pinkerton, E | 1 |
| Flatley, C | 1 |
| Gibbons, K | 1 |
| Allan, S | 1 |
| Liu, Z | 1 |
| Gambeta, E | 1 |
| Kopruszinski, CM | 1 |
| Dos Reis, RC | 1 |
| Zanoveli, JM | 1 |
| Chichorro, JG | 1 |
| Neville, DN | 1 |
| Hayes, KR | 1 |
| Ivan, Y | 1 |
| McDowell, ER | 1 |
| Pitetti, RD | 1 |
| Rolley, J | 1 |
| Sutherland, JR | 1 |
| Cameron, R | 1 |
| Wang, R | 1 |
| Wang, WH | 1 |
| Wejner-Mik, P | 1 |
| Sobczak, M | 1 |
| Miskowiec, D | 1 |
| Wdowiak-Okrojek, K | 1 |
| Kasprzak, JD | 1 |
| Lipiec, P | 1 |
| Elvir Lazo, OL | 1 |
| White, PF | 1 |
| Tang, J | 1 |
| Yumul, R | 1 |
| Cao, X | 1 |
| Yumul, F | 1 |
| Hausman, J | 1 |
| Hernandez Conte, A | 1 |
| Anand, KK | 1 |
| Hemaya, EG | 1 |
| Zhang, X | 1 |
| Wender, RH | 1 |
| Guerrier, G | 1 |
| Boutboul, D | 1 |
| Chanat, C | 1 |
| Samama, CM | 1 |
| Baillard, C | 1 |
| Ghai, B | 2 |
| Jain, K | 2 |
| Saxena, AK | 2 |
| Bhatia, N | 1 |
| Sodhi, KS | 1 |
| Khodadad, A | 1 |
| Aflatoonian, M | 1 |
| Jalilian, R | 1 |
| Babaei, N | 1 |
| Motamed, F | 1 |
| Ebrahime Soltani, A | 1 |
| Rasoolzadeh, B | 1 |
| Motavasselian, F | 1 |
| Rezaei, N | 1 |
| Cartabuke, RS | 1 |
| Tobias, JD | 1 |
| Rice, J | 1 |
| Tumin, D | 1 |
| Bumin Aydın, G | 1 |
| Yüksel, S | 1 |
| Ergil, J | 1 |
| Akelma, FK | 1 |
| Ekici, M | 1 |
| Sayın, M | 1 |
| Odabaş, Ö | 1 |
| Kim, MH | 1 |
| Kim, MS | 1 |
| Lee, JH | 2 |
| Seo, JH | 1 |
| Lee, JR | 1 |
| Manoj, M | 1 |
| Satya Prakash, MVS | 1 |
| Swaminathan, S | 1 |
| Kamaladevi, RK | 1 |
| Stern, CA | 1 |
| Carobrez, AP | 4 |
| Bertoglio, LJ | 3 |
| Proczkowska-Björklund, M | 1 |
| Runeson, I | 1 |
| Gustafsson, PA | 1 |
| Svedin, CG | 1 |
| Ramos, A | 1 |
| Pereira, E | 1 |
| Martins, GC | 1 |
| Wehrmeister, TD | 1 |
| dos Reis, LM | 1 |
| Canto-de-Souza, A | 3 |
| Sweeney, H | 1 |
| Marai, S | 1 |
| Kim, C | 1 |
| Ferrer, F | 1 |
| Sun, GC | 1 |
| Hsu, MC | 1 |
| Chia, YY | 1 |
| Chen, PY | 1 |
| Shaw, FZ | 1 |
| Mayordomo-Colunga, J | 1 |
| Medina, A | 1 |
| Rey, C | 1 |
| Díaz, JJ | 1 |
| Concha, A | 1 |
| Los Arcos, M | 1 |
| Menéndez, S | 1 |
| Zhang, S | 1 |
| Cranney, J | 1 |
| Golan, G | 1 |
| Tighe, P | 1 |
| Dobija, N | 1 |
| Perel, A | 1 |
| Keidan, I | 1 |
| Richart Aznar, MT | 1 |
| Fernández Bañuls, E | 1 |
| Lagardera Miñana, A | 1 |
| Aragón Alvarez, S | 1 |
| Chundamala, J | 1 |
| Wright, JG | 1 |
| Kemp, SM | 1 |
| Raines, T | 1 |
| Jones, P | 1 |
| Moe, N | 1 |
| Duncan, R | 1 |
| McCall, S | 5 |
| Barbalho, CA | 1 |
| Nunes-de-Souza, RL | 3 |
| Lazol, JP | 1 |
| DeGroff, CG | 1 |
| Bringman, H | 1 |
| Giesecke, K | 1 |
| Thörne, A | 1 |
| Bringman, S | 1 |
| Cavalli, J | 1 |
| Lesage, S | 1 |
| Drolet, P | 2 |
| Donati, F | 1 |
| Racine, S | 1 |
| Fortier, LP | 1 |
| Audy, D | 1 |
| Hedén, L | 1 |
| von Essen, L | 1 |
| Frykholm, P | 1 |
| Ljungman, G | 2 |
| Rosenbaum, A | 1 |
| Kain, ZN | 8 |
| Larsson, P | 1 |
| Lönnqvist, PA | 1 |
| Wolf, AR | 1 |
| Albrechet-Souza, L | 3 |
| Borelli, KG | 1 |
| Carvalho, MC | 2 |
| Wen, RJ | 1 |
| Leslie, K | 1 |
| Rajendra, P | 1 |
| Tajiri, O | 1 |
| Tateda, T | 1 |
| Ito, H | 1 |
| Yago, Y | 1 |
| Kanazawa, M | 1 |
| Shaikh, AA | 1 |
| Hussain, SM | 1 |
| Rahn, S | 1 |
| Desilets, DJ | 1 |
| Inagaki, H | 1 |
| Kiyokawa, Y | 1 |
| Takeuchi, Y | 1 |
| Mori, Y | 1 |
| Cao, J | 1 |
| Shi, X | 1 |
| Miao, X | 1 |
| Xu, J | 1 |
| Heese, T | 1 |
| Jenkinson, J | 1 |
| Love, C | 1 |
| Milam, R | 1 |
| Perkins, L | 1 |
| Adams, C | 1 |
| Templeton, P | 1 |
| Burton, D | 1 |
| Cullen, E | 1 |
| Lewis, H | 1 |
| Allgar, V | 1 |
| Wilson, R | 1 |
| Bignante, EA | 1 |
| Paglini, G | 1 |
| Zalunardo, MP | 1 |
| Ivleva-Sauerborn, A | 1 |
| Seifert, B | 1 |
| Spahn, DR | 1 |
| Saini, D | 1 |
| Khandelwal, N | 1 |
| Zhou, R | 1 |
| Wang, S | 1 |
| Zhu, X | 1 |
| Taracha, E | 1 |
| Maciejak, P | 4 |
| Szyndler, J | 4 |
| Hamed, A | 1 |
| Bidziński, A | 3 |
| Snyder, HR | 1 |
| Hutchison, N | 1 |
| Nyhus, E | 1 |
| Curran, T | 1 |
| Banich, MT | 1 |
| O'Reilly, RC | 1 |
| Munakata, Y | 1 |
| Vagnoli, L | 1 |
| Caprilli, S | 1 |
| Messeri, A | 1 |
| Barone, G | 2 |
| Rigante, D | 1 |
| Ruggiero, A | 1 |
| Pierri, F | 1 |
| Barbi, E | 1 |
| Riccardi, R | 1 |
| Lee, JJ | 1 |
| Kim, SS | 1 |
| Li, XY | 1 |
| Mercaldo, V | 1 |
| Descalzi, G | 1 |
| Wu, LJ | 1 |
| Zhuo, M | 1 |
| Cooper, CS | 1 |
| Ferguson, GG | 1 |
| Chen, C | 1 |
| Yan, Y | 1 |
| Royer, ME | 1 |
| Campigotto, M | 1 |
| Traxel, EJ | 1 |
| Coplen, DE | 1 |
| Austin, PF | 1 |
| Leiter, E | 1 |
| Hitchcock, G | 1 |
| Godwin, S | 1 |
| Johnson, M | 1 |
| Sedgwick, W | 1 |
| Jones, W | 1 |
| Litman, RS | 1 |
| Zutter, A | 1 |
| Frei, FJ | 1 |
| Darlong, V | 1 |
| Shende, D | 1 |
| Singh, M | 1 |
| Garg, R | 1 |
| Pandey, R | 1 |
| Punj, J | 1 |
| Rao, J | 1 |
| Kennedy, SE | 1 |
| Cohen, S | 1 |
| Rosenberg, AR | 1 |
| Darbra, S | 1 |
| Pallarès, M | 1 |
| Casarotto, PC | 1 |
| de Bortoli, VC | 1 |
| Akin, A | 1 |
| Bayram, A | 1 |
| Esmaoglu, A | 1 |
| Tosun, Z | 1 |
| Aksu, R | 1 |
| Altuntas, R | 1 |
| Boyaci, A | 1 |
| Kulkarni, S | 1 |
| Johnson, PC | 1 |
| Kettles, S | 1 |
| Kasthuri, RS | 1 |
| Hamid, M | 1 |
| Khan, MA | 1 |
| Khatri, A | 1 |
| Akhtar, I | 1 |
| Strøm, T | 1 |
| Hosseini Jahromi, SA | 1 |
| Hosseini Valami, SM | 1 |
| Adeli, N | 1 |
| Yazdi, Z | 1 |
| Demir, G | 1 |
| Cukurova, Z | 1 |
| Eren, G | 1 |
| Tekdos, Y | 1 |
| Hergunsel, O | 1 |
| Johnson, YJ | 1 |
| Nickerson, M | 1 |
| Quezado, ZM | 1 |
| Lan, YP | 1 |
| Huang, ZH | 1 |
| Finley, GA | 3 |
| Zuo, YX | 1 |
| Howell, TK | 1 |
| Smith, S | 1 |
| Rushman, SC | 1 |
| Walker, RW | 1 |
| Radivan, F | 1 |
| De Witte, JL | 1 |
| Alegret, C | 1 |
| Sessler, DI | 1 |
| Cammu, G | 1 |
| Dal-Cól, ML | 1 |
| Pereira, LO | 1 |
| Rosa, VP | 1 |
| Calixto, AV | 1 |
| McCool, BA | 1 |
| Frye, GD | 1 |
| Pulido, MD | 1 |
| Botting, SK | 1 |
| Yilmaz, E | 1 |
| Ozcan, S | 1 |
| Basar, M | 1 |
| Basar, H | 1 |
| Batislam, E | 1 |
| Ferhat, M | 1 |
| Khalil, SN | 1 |
| Vije, HN | 1 |
| Kee, SS | 1 |
| Farag, A | 1 |
| Hanna, E | 1 |
| Chuang, AZ | 1 |
| Caldwell-Andrews, AA | 2 |
| Wang, SM | 7 |
| Krivutza, DM | 4 |
| Weinberg, ME | 2 |
| Mayes, LC | 6 |
| Pojda-Wilczek, D | 1 |
| Stołtny, LG | 1 |
| Pojda, SM | 1 |
| Pojda, G | 1 |
| Sienkiewicz-Jarosz, H | 3 |
| Członkowska, AI | 2 |
| Kostowski, W | 2 |
| Heine, GH | 1 |
| Weindler, J | 2 |
| Gabriel, HH | 1 |
| Kindermann, W | 1 |
| Ruprecht, KW | 2 |
| Siemiatkowski, M | 2 |
| Wisłowska, A | 2 |
| Zienowicz, M | 1 |
| Masue, T | 1 |
| Shimonaka, H | 1 |
| Fukao, I | 1 |
| Kasuya, S | 1 |
| Kasuya, Y | 1 |
| Dohi, S | 1 |
| Hasen, KV | 1 |
| Samartzis, D | 1 |
| Casas, LA | 1 |
| Mustoe, TA | 1 |
| Kanegaye, JT | 1 |
| Favela, JL | 1 |
| Acosta, M | 1 |
| Bank, DE | 1 |
| Shah, AA | 1 |
| Treit, D | 4 |
| Marriott, P | 1 |
| Laasch, HU | 1 |
| Wilbraham, L | 1 |
| Marriott, A | 1 |
| England, RE | 1 |
| Martin, DF | 1 |
| Habib, NE | 1 |
| Mandour, NM | 1 |
| Balmer, HG | 1 |
| Gaal, D | 1 |
| McGregor, IS | 2 |
| Hargreaves, GA | 1 |
| Apfelbach, R | 1 |
| Hunt, GE | 1 |
| Bauer, KP | 1 |
| Dom, PM | 1 |
| Ramirez, AM | 1 |
| O'Flaherty, JE | 1 |
| Crowley, KL | 1 |
| Rehman, M | 1 |
| Schwartz, RE | 1 |
| Boodhoo, L | 1 |
| Mitchell, A | 1 |
| Ujhelyi, M | 1 |
| Sulke, N | 1 |
| Babin, E | 1 |
| Sigston, E | 1 |
| Bigeon, JY | 1 |
| Doppia, MA | 1 |
| Edy, E | 1 |
| Abreu-Rodrigues, J | 1 |
| Hanna, ES | 1 |
| de Mello Cruz, AP | 1 |
| Matos, R | 1 |
| Delabrida, Z | 1 |
| Mui, LM | 1 |
| Teoh, AY | 1 |
| Ng, EK | 1 |
| Lee, YT | 1 |
| Au Yeung, AC | 1 |
| Chan, YL | 1 |
| Lau, JY | 1 |
| Chung, SC | 1 |
| Geller, E | 1 |
| Calipel, S | 1 |
| Lucas-Polomeni, MM | 1 |
| Wodey, E | 1 |
| Ecoffey, C | 1 |
| Samarkandi, A | 1 |
| Naguib, M | 3 |
| Riad, W | 1 |
| Thalaj, A | 1 |
| Alotibi, W | 1 |
| Aldammas, F | 1 |
| Albassam, A | 1 |
| Yasoshima, Y | 1 |
| Yamamoto, T | 1 |
| Oliveira, AR | 1 |
| De Luca, MC | 1 |
| Tomazini, FM | 1 |
| Santos, NR | 1 |
| Pietraszek, M | 1 |
| Sukhanov, I | 1 |
| Gravius, A | 1 |
| Bespalov, AY | 1 |
| Danysz, W | 1 |
| Mendes-Gomes, J | 1 |
| Bessa, JM | 1 |
| Oliveira, M | 1 |
| Cerqueira, JJ | 1 |
| Almeida, OF | 1 |
| Sousa, N | 1 |
| Dikmen Mentes, S | 1 |
| Unsal, D | 1 |
| Baran, O | 1 |
| Argun, G | 1 |
| Ertunc, FN | 1 |
| Guimarães, FS | 4 |
| Beijamini, V | 1 |
| Moreira, FA | 2 |
| Aguiar, DC | 2 |
| de Lucca, AC | 1 |
| Jardim, MC | 1 |
| Masson, S | 1 |
| Martin, ML | 1 |
| Lennox, PH | 1 |
| Buckley, BT | 1 |
| Schupp, CJ | 1 |
| Berbaum, K | 1 |
| Berbaum, M | 1 |
| Lang, EV | 2 |
| Stewart, SH | 2 |
| Buffett-Jerrott, S | 1 |
| Wright, KD | 2 |
| Millington, D | 1 |
| Pekcan, M | 1 |
| Celebioglu, B | 1 |
| Demir, B | 1 |
| Saricaoglu, F | 1 |
| Hascelik, G | 1 |
| Yukselen, MA | 1 |
| Basgul, E | 1 |
| Aypar, U | 1 |
| Molina-Hernández, M | 1 |
| Tellez-Alcántara, NP | 1 |
| Pérez-García, J | 1 |
| Olivera-Lopez, JI | 1 |
| Jaramillo, MT | 1 |
| Hsiao, PC | 1 |
| Tang, YY | 1 |
| Liaw, WJ | 1 |
| Yue-Cune Chang, YH | 1 |
| Chen, FC | 1 |
| Wang, KY | 1 |
| Heldt, SA | 1 |
| Ressler, KJ | 1 |
| Patel, A | 1 |
| Schieble, T | 1 |
| Davidson, M | 1 |
| Tran, MC | 1 |
| Schoenberg, C | 1 |
| Delphin, E | 1 |
| Bennett, H | 1 |
| Tschirch, FT | 1 |
| Göpfert, K | 1 |
| Fröhlich, JM | 1 |
| Brunner, G | 1 |
| Weishaupt, D | 1 |
| Cox, RG | 1 |
| Nemish, U | 1 |
| Ewen, A | 1 |
| Crowe, MJ | 1 |
| Buffett-Jerrott, SE | 1 |
| Illievich, U | 1 |
| Lenhardt, R | 1 |
| Meybohm, P | 1 |
| Hanss, R | 1 |
| Bein, B | 1 |
| Schaper, C | 1 |
| Buttgereit, B | 1 |
| Scholz, J | 1 |
| Bauer, M | 1 |
| Schmidt, AP | 1 |
| Valinetti, EA | 1 |
| Bandeira, D | 1 |
| Bertacchi, MF | 1 |
| Simões, CM | 1 |
| Auler, JO | 1 |
| Bytzer, P | 1 |
| Lindeberg, B | 1 |
| MacLaren, J | 1 |
| McClain, BC | 1 |
| Saadat, H | 1 |
| Anderson, GM | 1 |
| Brown, E' | 1 |
| Hurd, NS | 1 |
| Almenrader, N | 1 |
| Passariello, M | 1 |
| Coccetti, B | 1 |
| Haiberger, R | 1 |
| Pietropaoli, P | 1 |
| Reza, N | 1 |
| Ali, SM | 1 |
| Saeed, K | 1 |
| Abul-Qasim, A | 1 |
| Reza, TH | 1 |
| Yüksel, O | 1 |
| Parlak, E | 1 |
| Köklü, S | 1 |
| Ertugrul, I | 1 |
| Tunç, B | 1 |
| Sahin, B | 1 |
| Cline, M | 1 |
| Taylor, JE | 1 |
| Flores, J | 1 |
| Bracken, S | 1 |
| Marc, I | 1 |
| Rainville, P | 1 |
| Masse, B | 1 |
| Verreault, R | 1 |
| Vaillancourt, L | 1 |
| Vallée, E | 1 |
| Dodin, S | 1 |
| Batllori Gastón, M | 1 |
| Gil Gorricho, MJ | 1 |
| Zaballos Barcala, N | 1 |
| Gracia Aznárez, MY | 1 |
| Urchaga Litago, A | 1 |
| Murillo Jason, E | 1 |
| Bonomo, JB | 1 |
| Butler, AS | 1 |
| Lindsell, CJ | 1 |
| Venkat, A | 1 |
| Sackey, PV | 1 |
| Martling, CR | 1 |
| Carlswärd, C | 1 |
| Sundin, O | 1 |
| Radell, PJ | 1 |
| Schmidt, A | 1 |
| Karlson-Stiber, C | 1 |
| Peterson, LJ | 1 |
| Vinik, HR | 1 |
| Reves, JG | 1 |
| Wright, D | 1 |
| Fragen, RJ | 1 |
| Funk, DI | 1 |
| Avram, MJ | 1 |
| Costello, C | 1 |
| DeBruine, K | 1 |
| Warner, DL | 1 |
| Cabaret, J | 1 |
| Velling, D | 1 |
| Lipp, M | 1 |
| Daubländer, M | 1 |
| Sebastian, M | 1 |
| Dick, W | 1 |
| Jalbout, N | 1 |
| Karam, AN | 1 |
| Karam, E | 1 |
| Feghaly, C | 1 |
| Khalaf, H | 1 |
| Vivian, JA | 1 |
| Weerts, EM | 1 |
| Pesold, C | 2 |
| Tago, N | 1 |
| Kanaya, N | 1 |
| Nakayama, M | 1 |
| Seki, S | 1 |
| Kawana, S | 1 |
| Nakiki, A | 1 |
| Cruz, AP | 1 |
| Frei, F | 1 |
| Graeff, FG | 5 |
| Jones, RD | 1 |
| Visram, AR | 1 |
| Kornberg, JP | 1 |
| Irwin, MG | 1 |
| Gunawardene, WM | 1 |
| Fatovich, DM | 1 |
| Jacobs, IG | 1 |
| Russo, AS | 2 |
| De Aguiar, JC | 2 |
| Maisonnette, S | 1 |
| Morato, S | 1 |
| Jaakola, ML | 1 |
| Kanto, J | 1 |
| Scheinin, H | 1 |
| Kallio, A | 1 |
| Bailine, SH | 1 |
| Safferman, A | 1 |
| Vital-Herne, J | 1 |
| Bernstein, S | 1 |
| Geddes, SM | 1 |
| Gray, WM | 1 |
| Asbury, AJ | 1 |
| McCluskey, A | 2 |
| Meakin, GH | 1 |
| Shane, SA | 1 |
| Fuchs, SM | 1 |
| Khine, H | 1 |
| Connors, K | 1 |
| Terndrup, TE | 2 |
| Baraff, LJ | 1 |
| Short, TG | 2 |
| Young, KK | 1 |
| Tan, P | 1 |
| Tam, YH | 1 |
| Gin, T | 1 |
| Oh, TE | 1 |
| Bates, BA | 1 |
| Schutzman, SA | 1 |
| Fleisher, GR | 1 |
| Hamilton, D | 1 |
| Kasaba, T | 2 |
| Boyd, O | 1 |
| Mackay, CJ | 1 |
| Rushmer, F | 1 |
| Bennett, ED | 1 |
| Grounds, RM | 1 |
| Motta, V | 2 |
| Theroux, MC | 1 |
| West, DW | 1 |
| Corddry, DH | 1 |
| Hyde, PM | 1 |
| Bachrach, SJ | 1 |
| Cronan, KM | 1 |
| Kettrick, RG | 1 |
| Khazin, V | 1 |
| Ezra, S | 1 |
| Cohen, A | 1 |
| Anseloni, VZ | 1 |
| Lima, G | 1 |
| Fletcher, D | 1 |
| Samii, K | 1 |
| Bénichou, A | 1 |
| Fillette, D | 1 |
| Bertin, A | 1 |
| Germond, M | 1 |
| Laverdisse, D | 1 |
| Mascaro, JM | 1 |
| Normand, E | 1 |
| Piroelle, Y | 1 |
| Ahmed, N | 1 |
| Khan, FA | 1 |
| Bernard, JM | 1 |
| Faintreny, A | 1 |
| Lienhart, A | 1 |
| Souron, R | 1 |
| Ellis, S | 1 |
| Tan, CC | 1 |
| Freeman, JG | 1 |
| Holland, IS | 1 |
| Stassen, LF | 1 |
| Cray, SH | 1 |
| Dixon, JL | 1 |
| Heard, CM | 1 |
| Selsby, DS | 1 |
| Gillerman, RG | 1 |
| Hinkle, AJ | 1 |
| Green, HM | 1 |
| Cornell, L | 1 |
| Dodge, CP | 1 |
| Gonzalez, LE | 3 |
| Andrews, N | 1 |
| File, SE | 4 |
| Walker, J | 1 |
| Mohamed, G | 1 |
| Lieblang, S | 1 |
| Manninen, PH | 1 |
| Chan, AS | 1 |
| Papworth, D | 1 |
| Cruise, CJ | 1 |
| Chung, F | 2 |
| Yogendran, S | 1 |
| Little, D | 1 |
| Ganapathy, S | 1 |
| Herrick, IA | 1 |
| Gelb, AW | 1 |
| Kirkby, J | 1 |
| Treggiari-Venzi, M | 1 |
| Borgeat, A | 1 |
| Fuchs-Buder, T | 1 |
| Gachoud, JP | 1 |
| Suter, PM | 1 |
| Riva, J | 1 |
| Lejbusiewicz, G | 1 |
| Papa, M | 1 |
| Lauber, C | 1 |
| Kohn, W | 1 |
| Da Fonte, M | 1 |
| Burgstaller, H | 1 |
| Comellas, C | 1 |
| Ayala, W | 1 |
| Schmit, P | 1 |
| Sfez, M | 1 |
| Patel, D | 1 |
| Meakin, G | 1 |
| Hines, AH | 1 |
| Labbate, LA | 1 |
| Goldberger, JJ | 1 |
| Kruse, J | 1 |
| Parker, MA | 1 |
| Kadish, AH | 1 |
| Notterman, DA | 1 |
| Liacouras, CA | 1 |
| Mascarenhas, M | 1 |
| Poon, C | 1 |
| Wenner, WJ | 1 |
| Holm-Knudsen, RJ | 1 |
| Carlin, JB | 1 |
| McKenzie, IM | 1 |
| Kennedy, RM | 2 |
| Porter, FL | 1 |
| Miller, JP | 1 |
| Jaffe, DM | 1 |
| Caramico, LA | 2 |
| Hofstadter, MB | 3 |
| Ouagazzal, AM | 1 |
| Steinlauf, AF | 1 |
| Garcia-Tsao, G | 1 |
| Zakko, MF | 1 |
| Dickey, K | 1 |
| Gupta, T | 1 |
| Groszmann, RJ | 1 |
| Viana, MB | 1 |
| Early, DS | 1 |
| Saifuddin, T | 1 |
| Johnson, JC | 1 |
| King, PD | 1 |
| Marshall, JB | 1 |
| Nazar, M | 1 |
| Członkowska, A | 1 |
| Samarkandi, AH | 2 |
| Kuganeswaran, E | 1 |
| Clarkston, WK | 1 |
| Cuddy, PG | 1 |
| Quiason, SG | 1 |
| Pandya, PK | 1 |
| Dierenfeldt, WT | 1 |
| Jonnalagadda, SS | 1 |
| Smith, OJ | 1 |
| Chen, ST | 1 |
| Dielenberg, RA | 1 |
| Kreuger, A | 1 |
| Andréasson, S | 1 |
| Gordh, T | 1 |
| Sörensen, S | 1 |
| Sherwin, TS | 1 |
| Green, SM | 1 |
| Khan, A | 1 |
| Chapman, DS | 1 |
| Dannenberg, B | 1 |
| McAllister, JD | 1 |
| D'Agostino, J | 1 |
| McHardy, FE | 1 |
| Fortier, J | 1 |
| Krishnathas, A | 1 |
| Marshall, SI | 1 |
| Sevarino, F | 1 |
| Pincus, S | 1 |
| Alexander, GM | 1 |
| Ayoub, C | 1 |
| Kosarussavadi, B | 1 |
| da-Costa, M | 1 |
| Fornari, RV | 1 |
| Pelá, IR | 1 |
| Alexander, G | 1 |
| Reznick, JS | 1 |
| Menard, J | 1 |
| Martens-Lobenhoffer, J | 1 |
| Eisenhardt, S | 1 |
| Tröger, U | 1 |
| Röse, W | 1 |
| Meyer, FP | 1 |
| Baris, S | 1 |
| Karakaya, D | 1 |
| Aykent, R | 1 |
| Kirdar, K | 1 |
| Sagkan, O | 1 |
| Tür, A | 1 |
| Younge, PA | 1 |
| Kendall, JM | 1 |
| Nguyen, TH | 1 |
| Phillips, PK | 1 |
| Lepage, C | 1 |
| Girard, M | 1 |
| Grenier, Y | 1 |
| DeGagné, R | 1 |
| Abdul-Latif, MS | 1 |
| Putland, AJ | 1 |
| Meadows, DP | 1 |
| Remington, SA | 1 |
| Froehlich, F | 1 |
| Coté, CJ | 1 |
| Cohen, IT | 1 |
| Rabb, M | 1 |
| Rose, JB | 1 |
| Weldon, BC | 1 |
| Davis, PJ | 1 |
| Bikhazi, GB | 1 |
| Karl, HW | 1 |
| Hummer, KA | 1 |
| Hannallah, RS | 1 |
| Khoo, KC | 1 |
| Collins, P | 1 |
| Falzone, TL | 1 |
| Gelman, DM | 1 |
| Young, JI | 1 |
| Grandy, DK | 1 |
| Low, MJ | 1 |
| Rubinstein, M | 1 |
| Frank, T | 1 |
| Wehner, M | 1 |
| Heinke, W | 1 |
| Schmädicke, I | 1 |
| Salonen, M | 1 |
| Onaivi, ES | 1 |
| Maze, M | 1 |
| Stefański, R | 1 |
| Pałejko, W | 1 |
| Skelly, AM | 2 |
| Girdler, NM | 1 |
| Sandler, ES | 1 |
| Weyman, C | 1 |
| Conner, K | 1 |
| Reilly, K | 1 |
| Dickson, N | 1 |
| Luzins, J | 1 |
| McGorray, S | 1 |
| Egan, KJ | 1 |
| Ready, LB | 3 |
| Nessly, M | 1 |
| Greer, BE | 1 |
| Parnis, SJ | 1 |
| Foate, JA | 1 |
| van der Walt, JH | 1 |
| Short, T | 1 |
| Crowe, CE | 1 |
| Jakobsson, J | 1 |
| Andersson, L | 1 |
| Nilsson, A | 1 |
| Davidson, S | 1 |
| Askergren, J | 1 |
| Luyk, NH | 1 |
| Whitley, BD | 1 |
| Turner, GA | 1 |
| Paech, M | 1 |
| Maestripieri, D | 1 |
| Martel, FL | 1 |
| Nevison, CM | 1 |
| Simpson, MJ | 1 |
| Keverne, EB | 1 |
| Rodríguez Núñez, A | 1 |
| Martinón Sánchez, JM | 1 |
| Rivas Pumar, P | 1 |
| Martínez Soto, I | 1 |
| Relova Quinteiro, JL | 1 |
| Peña Guitián, J | 1 |
| Kolek, V | 1 |
| Jezdinský, J | 1 |
| Pippingsköld, K | 1 |
| Lehtinen, AM | 1 |
| Laatikainen, T | 1 |
| Hänninen, H | 1 |
| Korttila, K | 1 |
| Friedman, AG | 1 |
| Mulhern, RK | 1 |
| Fairclough, D | 1 |
| Ward, PM | 1 |
| Baker, D | 1 |
| Mirro, J | 1 |
| Rivera, GK | 1 |
| Antrobus, JH | 1 |
| Abbott, P | 1 |
| Carr, CM | 1 |
| Chatrath, RR | 1 |
| Dubost, J | 1 |
| Roche, C | 1 |
| Kalfon, F | 1 |
| van der Bijl, P | 2 |
| Roelofse, JA | 3 |
| Joubert, JJ | 3 |
| van Zyl, JF | 1 |
| Stegmann, DH | 1 |
| Hartshorne, J | 1 |
| Emmanouil, DE | 1 |
| Quock, RM | 1 |
| Lindahl, SG | 1 |
| Hennes, HM | 1 |
| Wagner, V | 1 |
| Bonadio, WA | 1 |
| Glaeser, PW | 1 |
| Losek, JD | 1 |
| Walsh-Kelly, CM | 1 |
| Smith, DS | 1 |
| Jakobbson, J | 1 |
| Andreen, M | 1 |
| Westgren, M | 1 |
| Thomasson, K | 1 |
| Beauvoir, C | 1 |
| Peschaud, JL | 1 |
| Pares-Herbute, N | 1 |
| du Cailar, J | 1 |
| Galletly, DC | 1 |
| Finley, PR | 1 |
| Nolan, PE | 1 |
| Klapproth, CE | 1 |
| Bein, T | 1 |
| Bauer, C | 1 |
| Nightingale, JJ | 1 |
| Norman, J | 1 |
| Hargreaves, J | 1 |
| Loper, KA | 2 |
| Levy, L | 1 |
| Pandit, SK | 2 |
| Taylor, MB | 1 |
| Vine, PR | 1 |
| Hatch, DJ | 1 |
| Nelson, IA | 1 |
| Barker, I | 1 |
| Butchart, DG | 1 |
| Gibson, J | 1 |
| Lawson, JI | 1 |
| Mackenzie, N | 1 |
| Artru, AA | 1 |
| Dhamee, MS | 1 |
| Seifen, AB | 1 |
| Wright, B | 1 |
| Takrouri, MS | 1 |
| Toukan, A | 1 |
| Badran, I | 1 |
| Sbeih, Z | 1 |
| Hunjul, N | 1 |
| Breytenbach, HS | 1 |
| van Wijhe, M | 1 |
| de Voogt-Frenkel, E | 1 |
| Stijnen, T | 1 |
| Brody, M | 1 |
| Saarnivaara, L | 1 |
| Lindgren, L | 1 |
| Klemola, UM | 1 |
| O'Boyle, CA | 1 |
| Harris, D | 1 |
| Barry, H | 1 |
| McCreary, C | 1 |
| Bewley, A | 1 |
| Fox, E | 1 |
| Raybould, D | 1 |
| Bradshaw, EG | 1 |
| Khanderia, U | 1 |
| Dochy, M | 1 |
| Mekkey, ME | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Three Different Interventions on Preoperative Anxiety in Children[NCT03530670] | Phase 4 | 138 participants (Actual) | Interventional | 2018-08-06 | Completed | ||
| Premedication With Melatonin vs. Placebo in Patients Undergoing Interventional Pain Procedure[NCT02415309] | Phase 3 | 25 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| SurgerySMART: Studying Melatonin and Recovery in Teens[NCT06093477] | 40 participants (Anticipated) | Interventional | 2024-07-31 | Not yet recruiting | |||
| Anxiolytic and Analgesic Effects of Melatonin: A Randomized, Double-blinded, Placebo-controlled Clinical Study[NCT02386319] | Phase 3 | 36 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Perioperative Analgesic and Anxiolytic Effect of Melatonin in Patients Undergoing Lumbar Laminectomy[NCT01126294] | 84 participants (Anticipated) | Interventional | 2010-04-30 | Recruiting | |||
| Use of Melatonin for Prevention of POCD After TURP Surgery Under Spinal Anesthesia for Elderly Patients[NCT03966950] | 104 participants (Anticipated) | Interventional | 2017-06-26 | Recruiting | |||
| The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome[NCT02451293] | Phase 2/Phase 3 | 252 participants (Actual) | Interventional | 2016-01-18 | Completed | ||
| Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound[NCT03829618] | Phase 3 | 29 participants (Actual) | Interventional | 2019-04-01 | Terminated (stopped due to COVID lack of cases/recruitment) | ||
| Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in Children[NCT04586504] | Phase 1/Phase 2 | 150 participants (Anticipated) | Interventional | 2021-09-08 | Recruiting | ||
| Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial[NCT06181695] | Phase 3 | 182 participants (Anticipated) | Interventional | 2024-05-02 | Not yet recruiting | ||
| Intranasal Dexmedetomidine and Fentanyl Versus Intravenous Midazolam and Ketamine in Sedation for Painful Outpatient Procedures[NCT04621110] | Phase 3 | 60 participants (Anticipated) | Interventional | 2021-06-01 | Not yet recruiting | ||
| Non-interventional Comparison of Sedatives on Weaning From Mechanical Ventilation in Intensive Care Patients[NCT01707680] | 155 participants (Actual) | Observational | 2012-06-01 | Terminated (stopped due to Halted due to slow recruitment) | |||
| A Randomized Controlled Trial of Intranasal Fentanyl in Combination With Midazolam Versus Midazolam Alone for Analgesia and Anxiolysis During Pediatric Facial Laceration Repair[NCT04745260] | 100 participants (Anticipated) | Interventional | 2021-03-01 | Not yet recruiting | |||
| Use of an Adaptive Sensory Environment in Autism Spectrum Disorder (ASD) Patients in the Perioperative Environment[NCT04994613] | 60 participants (Actual) | Interventional | 2021-09-20 | Completed | |||
| The Effect of Visualized Education and Distraction in the Preoperative Process on Reducing the Anxiety of Children and Their Parents: A Randomized Controlled Study[NCT05279976] | 210 participants (Anticipated) | Interventional | 2023-06-06 | Recruiting | |||
| Comparison of the Effectiveness of Two Different Distraction Interventions in Reducing Preoperative Anxiety of Children and Parents Who Are Scheduled for Elective Surgery: A Randomized Controlled Study[NCT05538039] | 210 participants (Anticipated) | Interventional | 2022-09-16 | Recruiting | |||
| Intelligent Customer-driven Solution for Children and Their Parents Undergoing Children´s Day Surgery[NCT04277299] | 40 participants (Actual) | Interventional | 2020-08-12 | Completed | |||
| A Comparison of Midazolam or Haloperidol Premedication Versus Placebo for Reducing Ketamine Induced Agitation After Adult Procedural Sedation in the Emergency Department[NCT02909465] | Phase 4 | 185 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine[NCT04746079] | 180 participants (Anticipated) | Interventional | 2021-02-05 | Recruiting | |||
| Dexmedetomidine vs. Midazolam for Facilitating Extubation in Medical and Surgical ICU Patients: A Randomized, Double-Blind Study[NCT00744380] | 23 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Comparing the Effectiveness of Virtual Reality Versus Control Group in Reducing Preoperative Anxiety in Pediatric Patients[NCT06044753] | 60 participants (Actual) | Interventional | 2020-12-01 | Completed | |||
| A Comparison of Virtual Reality Headset and Touch Screen Tablet for Minimizing Anxiety During Separation From Caregiver and Induction of Anesthesia in Children[NCT04414501] | 94 participants (Actual) | Interventional | 2018-04-30 | Completed | |||
| Impact of Preanesthetic Information and Behavioral Intervention Using Smartphone Application on Anxiety of Children[NCT02246062] | 84 participants (Actual) | Interventional | 2013-06-30 | Completed | |||
| The Effects of Operating Room Virtual Tour on Preoperative Anxiety, Emergence Delirium and Postoperative Behavioral Changes of Pediatric Patients: Prospective, Randomized, and Controlled Trial[NCT03172182] | 86 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| Does the Preoperative Midazolam Dose Affect Postoperative Pain? - a Multicentric Randomized Controlled Trial in Ambulatory Surgery[NCT03534895] | Phase 4 | 168 participants (Anticipated) | Interventional | 2019-05-31 | Not yet recruiting | ||
| Does Preoperative Midazolam Dose Affect Postoperative Pain? - a Multicentric Observational Study in Open Inguinal Hernia Repair[NCT03499730] | 300 participants (Actual) | Observational | 2018-09-12 | Completed | |||
| Developing and Testing the Effectiveness of Intelligent Customer-driven Solution for Pediatric Surgery Care on the Improvement of Outcomes of Parents and Their Children Undergoing Circumcision[NCT04174404] | 160 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | |||
| Comparison of Usual Care and Distraction (Tablet) on Anxiety and Length of Stay Between in Children 3-5 Years Old[NCT05368961] | 99 participants (Actual) | Interventional | 2017-04-07 | Completed | |||
| An Evaluation of Oral Midazolam for Anxiety and Pain in First-trimester Surgical Abortion: a Randomized Controlled Trial[NCT01830881] | Phase 4 | 124 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Exploring the Effects of an Informative Animated Video on Preoperative Anxiety in Children Undergoing Elective Otoplasty and Their Parents[NCT05894187] | 40 participants (Anticipated) | Interventional | 2023-06-30 | Not yet recruiting | |||
| Randomized Controlled Trial of IN Midazolam vs IN Dexmedetomidine vs IN Ketamine Evaluating Length of Stay After Medication Administration and Anxiolysis During Minimal Procedures in Pediatric Population in Pediatric Emergency Department[NCT05934669] | Phase 4 | 90 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| Intranasal Sedation With Dexmedetomidine for Vitroretinal Procedures[NCT03251222] | Phase 4 | 40 participants (Anticipated) | Interventional | 2017-01-01 | Recruiting | ||
| Prospective, Randomized, Double-blind, Double-dummy, Active-controlled, Phase 3 Clinical Trial Comparing the Safety and Efficacy of Intranasal Dexmedetomidine to Oral Midazolam as Premedication for Propofol Sedation in Pediatric Patients Undergoing Magnet[NCT05192629] | Phase 3 | 250 participants (Anticipated) | Interventional | 2022-03-09 | Recruiting | ||
| Effects of Premedication by Midazolam on Preoperative Anxiety for Emergency Surgery[NCT02213302] | Phase 4 | 59 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Comparison Between Music Therapy and Intravenous Midazolam 0,02 mg/kgBW in Reducing Preoperative Anxiety: Study on Patient Undergoing Brachytherapy With Spinal Anesthesia[NCT03269929] | 60 participants (Actual) | Interventional | 2017-01-01 | Completed | |||
| The Efficacy and Safety of Gastric Feeding in Critically Ill Pediatric Patients Receiving Non-invasive Positive Pressure Ventilation: A Pilot Study[NCT01301352] | 30 participants (Actual) | Interventional | 2011-02-28 | Completed | |||
| The Effect of Dream Doctors in Children Undergoing Digestive Endoscopic Procedures: Physiological and Biological Assessment of Emotional and Cognitive Consequences[NCT02668679] | 99 participants (Actual) | Interventional | 2016-03-30 | Completed | |||
| Can Medical Clowns Prevent the Usage of Sedation During the Performance of EEG in Young Children[NCT05257096] | 100 participants (Anticipated) | Interventional | 2019-05-01 | Recruiting | |||
| The Effects of Music & Auditory Beat Stimulation on Anxiety[NCT05171218] | 163 participants (Actual) | Interventional | 2020-07-09 | Completed | |||
| Music and Auditory Beat Stimulation and Its Effect on Anxiety[NCT05442086] | 100 participants (Anticipated) | Interventional | 2022-08-15 | Not yet recruiting | |||
| The Effect of Intraoperative Music Listening on Sevoflurane Consumption and Recovery Parameters[NCT02220452] | 60 participants (Anticipated) | Interventional | 2014-08-31 | Recruiting | |||
| Low Dose Fentanyl/Midazolam Improves Sevoflurane Induction in Adults[NCT00723164] | 80 participants (Actual) | Interventional | 2005-10-31 | Completed | |||
| Automated Telephone Reminder Prior to Outpatient Colonoscopy and the Effect on Bowel Preparation Quality[NCT02478918] | 234 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| Intranasal Lidocaine to Treat Pediatric Migraine in the Emergency Department[NCT03576820] | Phase 3 | 50 participants (Anticipated) | Interventional | 2018-10-15 | Recruiting | ||
| Evaluating Stress Response and Anxiety Score in Paediatric Patients Sedated With Intranasal Dexmedetomidine[NCT04526652] | Phase 2 | 60 participants (Actual) | Interventional | 2020-12-01 | Completed | ||
| Comparing Intranasal Dexmedetomidine With Oral Midazolam as Premedication for Older Children Undergoing General Anesthesia for Dental Rehabilitation[NCT02250703] | Phase 3 | 75 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Music Therapy in Procedural Sedation in the Emergency Department[NCT02676206] | 60 participants (Actual) | Interventional | 2016-02-29 | Completed | |||
| Anxiolysis for Emergency Department Procedures in Pediatric Patients Using Intranasal Ketamine Compared With Intranasal Midazolam: A Randomized Controlled Trial[NCT03043430] | Phase 4 | 10 participants (Actual) | Interventional | 2016-05-31 | Terminated (stopped due to Research manpower shortage) | ||
| Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone: a Randomized, Double Blind Placebo Controlled Study[NCT01486615] | Phase 4 | 80 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| Comparison of Two Different Distraction Methods Affecting the Level of Pain and Anxiety During Extracorporeal Shock Wave Lithotripsy[NCT02725281] | 120 participants (Actual) | Interventional | 2014-04-30 | Completed | |||
| A Randomized Controlled Trial to Evaluate the Effects of Music Therapy on Breastfeeding Rates Among Mothers of Premature Newborns[NCT00930761] | 101 participants (Actual) | Interventional | 2004-03-31 | Completed | |||
| Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety: A Randomized Control Trial.[NCT02286674] | 200 participants (Actual) | Interventional | 2014-11-30 | Completed | |||
| The Effects of Single-dose Rectal Midazolam Application on Post-operative Recovery, Sedation, and Analgesia in Children Given Caudal Anesthesia Plus Bupivacaine[NCT02127489] | Phase 4 | 40 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
| The Effect of Pre Surgery Dog Visits on Post Surgery Consumption of Pain Medication[NCT00452738] | 0 participants (Actual) | Interventional | 2007-04-30 | Withdrawn (stopped due to PI left university. Did not start study) | |||
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol in Mechanically Ventilated Traumatic Brain Injury Patient: RCT[NCT04034771] | Phase 3 | 38 participants (Actual) | Interventional | 2018-01-01 | Completed | ||
| Management of Perioperative Anxiety by the Fixed Rate Guided Breathing Technique (Cardiac Coherence) Coupled With a Hypnosis Session, as Part of the Improved Pre-habilitation After Surgery[NCT03981731] | 53 participants (Actual) | Interventional | 2020-02-14 | Completed | |||
| Phase III Study Evaluating a Non-drug Intervention (NDI) Program by Fixed-frequency Guided Breathing (Cardiac Coherence) Associated With Medical Hypnosis on Preoperative Anxiety in Oncological Surgery[NCT05197972] | 296 participants (Anticipated) | Interventional | 2022-04-21 | Recruiting | |||
| Digital Game MentalPlus®: A Scale to Evaluate on Perioperative Cognitive Function: Content Analysis, Internal Consistency, Convergent Validity and Clinical Validation of the Diagnostic Test[NCT02551952] | 100 participants (Anticipated) | Interventional | 2021-07-08 | Recruiting | |||
| Assessing an Active Distracting Technique During Pulpotomy in Primary Mandibular Molar.[NCT05191836] | 105 participants (Actual) | Interventional | 2021-08-15 | Completed | |||
| The Effect of Two Distraction Strategies in Reducing Preoperative Anxiety in Children：A Randomized Controlled Trial[NCT05285995] | 181 participants (Actual) | Interventional | 2019-04-07 | Completed | |||
| Comparing Pediatric Oral Sedation Outcomes Using Midazolam and Hydroxyzine With and Without Meperidine[NCT04068948] | Phase 4 | 37 participants (Actual) | Interventional | 2019-06-25 | Completed | ||
| Investigation of the DNA Methylation Profile in Children Who Presented Emergence Delirium[NCT03787849] | 175 participants (Actual) | Interventional | 2018-09-24 | Completed | |||
| The Effect of Turkish Classical Music on Postpartum Pain and Anxiety in Women Who Delivered Via Cesarean Section[NCT04111575] | 126 participants (Actual) | Interventional | 2018-02-05 | Completed | |||
| Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP[NCT01404689] | Phase 4 | 110 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP)[NCT02027311] | Phase 4 | 63 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Evaluation of Mirus™ for Sedation in Resuscitation[NCT02889055] | 9 participants (Actual) | Observational | 2016-01-17 | Terminated (stopped due to Safety profile was not satisfying with sevolflurane) | |||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-06-30 | Recruiting | ||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-04-28 | Recruiting | ||
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| Nebulized Lidocaine and Intranasal Midazolam for Reducing Pain/Anxiety of Nasogastric Tube Insertion in Children: A Randomized Clinical Trial[NCT04571879] | Phase 3 | 48 participants (Anticipated) | Interventional | 2021-08-25 | Recruiting | ||
| Prospective Comparison of Single vs. Staged Extractions: OHRQoL Outcomes for Wisdom Teeth Removal[NCT05820867] | 59 participants (Actual) | Interventional | 2018-03-01 | Completed | |||
| Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050] | Phase 4 | 50 participants (Actual) | Interventional | 2006-08-31 | Completed | ||
| Systemic Absorption of Lidocaine After Ultrasound Guided Hematoma Block for Reduction of Different Types of Pediatric Distal Radius Fractures[NCT04359017] | Phase 4 | 0 participants (Actual) | Interventional | 2020-11-01 | Withdrawn (stopped due to Sponsoring staff have left institution) | ||
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Does Anxiety in Children on the Day of Surgery Impact Compliance in the Ophthalmology Clinic?[NCT02704442] | 82 participants (Anticipated) | Observational | 2016-02-29 | Recruiting | |||
| Perioperative EEG-Monitoring and Emergence Delirium in Children: a Prospective Observational Study[NCT04091724] | 400 participants (Anticipated) | Observational | 2019-12-02 | Recruiting | |||
| Adaptive Care in the Perioperative Setting: An Observational Study[NCT03353129] | 60 participants (Actual) | Observational | 2017-08-15 | Completed | |||
| Impact of Fentanyl Analgesia on the Accuracy of Hepatic Venous Pressure Gradient Measurements in Patients With Portal Hypertension：a Prospective, Multicenter Study[NCT04724148] | 4 participants (Anticipated) | Interventional | 2022-01-01 | Recruiting | |||
| Prospective RCT of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy[NCT03160859] | 280 participants (Actual) | Interventional | 2018-06-08 | Completed | |||
| Double-blind, Randomized, Placebo-controlled Study on the Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing Intrauterine System[NCT02799641] | 61 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| Midazolam Effect on Agitation Postnasal Surgery: A Double Blinded Randomized Controlled Trial[NCT05165914] | 100 participants (Actual) | Interventional | 2021-05-27 | Completed | |||
| A Prospective Randomised Controlled Trial to Investigate the Effects of Intra-operative Music on Anxiety Levels During Procedures Under Spinal Anaesthesia at a Surgical Centre in Cambodia[NCT04169971] | 24 participants (Actual) | Interventional | 2019-10-28 | Completed | |||
| The Effect of Music Therapy on Postoperative Pain Anxiety and Vital Signs in Patients Undergoing Spinal Anaesthesia: a Randomized Controlled Trial[NCT04485650] | 90 participants (Actual) | Interventional | 2017-02-24 | Completed | |||
| Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies[NCT02518919] | 63 participants (Actual) | Interventional | 2015-10-01 | Completed | |||
| Effects of Clonidine and Midazolam Premedication on Bispectral Index and Recovery After Elective Surgery[NCT00638729] | 60 participants (Actual) | Interventional | 2005-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The State scale of the State-Trait Anxiety Inventory (STAI). Construct: Current level of anxiety. Scale range: 20-40 (higher scores indicate higher level of current anxiety) Scores are calculated according to the STAI scoring manual by adding point from each item (possible point for each item is 1-4)." (NCT02386319)
Timeframe: 60 minutes preoperative
| Intervention | score on a scale (Median) |
|---|---|
| Melatonin | 27 |
| Placebo | 28 |
Total alfentanyl dosing by anesthesia in mcg/kg (NCT03829618)
Timeframe: 1 day
| Intervention | mcg/kg (Mean) |
|---|---|
| Topical Lidocaine | 16.61 |
| Nebuliser Solution | 47.99 |
| Atomizer Solution | 4.40 |
time in minutes from scope out until ready for transport to post anesthesia care unit (NCT03829618)
Timeframe: 1 day
| Intervention | minutes (Mean) |
|---|---|
| Topical Lidocaine | 8.47 |
| Nebuliser Solution | 13.00 |
| Atomizer Solution | 6.14 |
Number of coughs during procedure as defined by cough requiring stopping procedure or treatment by anesthesiologist with propofol or alfentanyl (NCT03829618)
Timeframe: 1 day
| Intervention | coughs (Mean) |
|---|---|
| Topical Lidocaine | 1.20 |
| Nebuliser Solution | 1.71 |
| Atomizer Solution | 1.00 |
total fentanyl dosing by anesthesia in mcg/kg (NCT03829618)
Timeframe: 1 day
| Intervention | mcg/kg (Mean) |
|---|---|
| Topical Lidocaine | 0.30 |
| Nebuliser Solution | 0.24 |
| Atomizer Solution | 0.48 |
Total propofol dosing by anesthesia in mg/kg (NCT03829618)
Timeframe: 1 day
| Intervention | mg/kg (Mean) |
|---|---|
| Topical Lidocaine | 5.30 |
| Nebuliser Solution | 6.93 |
| Atomizer Solution | 3.26 |
(NCT00744380)
Timeframe: Duration of ICU stay, up to 24 weeks
| Intervention | days (Median) |
|---|---|
| Midazolam | 3 |
| Dexmedetomidine | 3.5 |
"The ICU-SEQ assesses patient recall of their ICU experience. The ICU-SEQ assesses both psychological (e.g. fearfulness, anxiety) and physical (e.g. pain, difficulty breathing) perceptions of ICU patients who have received mechanical ventilation. It consists of 29 potentially stressful experiences with seven items specifically addressing the endotracheal tube. The extent that patients are bothered by each item is scored on a five point scale: 0 = not at all, 1 = a little bit, 2 = moderately, 3 = quite a bit, and 4 = extremely. The cumulative score is an integer interpreted as interval data with higher scores indicating greater stressful experiences associated with the ICU. The minimum score is 0 and the maximum score possible is 116." (NCT00744380)
Timeframe: Duration of hospital stay, up to 24 weeks
| Intervention | units on a scale (Median) |
|---|---|
| Midazolam | 8.5 |
| Dexmedetomidine | 18.5 |
"The IES-R evaluates subjective distress caused by traumatic events and assesses manifestations of post-traumatic stress disorder (PTSD) or acute stress disorder. It is not diagnostic but possesses excellent reliability and validity for manifestations of PTSD. The IES-R has three subscales (eight items on intrusion, eight items on avoidance, and six items on hyperarousal). Each item is scored on a four point scale: 0 = not at all, 1 = a little bit, 2 = moderately often, 3 = quite a bit, and 4 = extremely often. The total score of each subscale may be averaged and a cumulative score of 30 is indicative of the presence of PTSD. The maximum score for each subscale is 32 for intrusion, 32 for avoidance, and 24 for hyperarousal. The minimum cumulative score is 0 and the maximum cumulative score possible is 88." (NCT00744380)
Timeframe: Duration of hospital stay, up to 24 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Midazolam | 13 |
| Dexmedetomidine | 36 |
(NCT00744380)
Timeframe: Duration of ICU stay, for up to 24 weeks
| Intervention | days (Median) |
|---|---|
| Midazolam | 2.9 |
| Dexmedetomidine | 3.4 |
(NCT00744380)
Timeframe: Duration of ICU stay, for up to 24 weeks
| Intervention | mg (Median) | ||
|---|---|---|---|
| Open-label midazolam while on study drug | All midazolam whil eon study drug | All fentanyl while on study drug | |
| Dexmedetomidine | 65.3 | 65.3 | 4.1 |
| Midazolam | 29 | 126.9 | 5.4 |
The HADS consists of 14 questions, seven for anxiety and seven for depression. Each item is scored from 0 to 3, with a cut-off cumulative score of 11 for both subscales indicative of anxiety or depression. This scoring tool has been used for 30 years, possesses excellent reliability and validity, and avoids reliance conditions that are also common somatic symptoms of illness such fatigue, insomnia, and hypersomnia. The maximum score for each subscale is 21 with a maximum possible cumulative score of 42. The minimum score for each subscale is 0. The minimum cumulative score is 0 (NCT00744380)
Timeframe: Duration of hospital stay, up to 24 weeks
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Anxiety | Depression | |
| Dexmedetomidine | 6 | 4 |
| Midazolam | 3 | 6 |
(NCT00744380)
Timeframe: Duration of ICU stay, up to 24 weeks
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| Hypotension | Bradycardia | Tachycardia | Delirium, new onset | |
| Dexmedetomidine | 10 | 7 | 7 | 1 |
| Midazolam | 6 | 7 | 5 | 5 |
The Riker sedation-agitation score (range 1-7) and PABS (range 0-10) are assessed hourly by the bedside nurse. Riker scores assess restlessness and cooperation. Riker scores of 5 - 7 indicate agitation, 3 - 4 represent adequate sedation and 1 - 2 represent excessive sedation. PABS assessments include domains of restlessness, muscle tone, vocalization, consolability, and facial expressions. PABS assessments of 0 represent no pain, 1 - 3 represent mild pain, 4 - 6 represent moderate pain, and ≥ 7 represent severe pain. (NCT00744380)
Timeframe: Duration of ICU stay, for up to 24 weeks
| Intervention | percentage of assessments while on study (Number) | |||
|---|---|---|---|---|
| Riker score 1-2 while on study drug | Riker score 3-4 while on study drug | Riker score 5-7 while on study drug | Pain score > 3 while on study drug | |
| Dexmedetomidine | 4.1 | 71.2 | 27.1 | 21.4 |
| Midazolam | 5.4 | 84.1 | 6.6 | 13.3 |
The level of child's anxiety will be measure by modified Yale Preoperative Anxiety Scale (m-YPAS). The total score of m-YPAS was calculated according to what was originally proposed by Kain et al. The total scores range from 23,4 until 100. Cut-off scores to classify patients with or without anxiety were: without anxiety (23.4 - 30), with anxiety (< 30). (NCT02246062)
Timeframe: 24 hours before surgery
| Intervention | units on a scale m-YPAS (Mean) |
|---|---|
| Control Group | 27.8 |
| Info Group | 24.18 |
| Smartphone Group | 23.79 |
| Smartphone and Info Group | 24.98 |
The level of child's anxiety will be measure by modified Yale Preoperative Anxiety Scale (m-YPAS). The total score of m-YPAS was calculated according to what was originally proposed by Kain et al. The total scores range from 23,4 until 100. Cut-off scores to classify patients with or without anxiety were: without anxiety (23.4 - 30), with anxiety (> 30). (NCT02246062)
Timeframe: Immediately before induction of anesthesia
| Intervention | units on a scale m-YPAS (Mean) |
|---|---|
| Control Group | 51.13 |
| Info Group | 30.29 |
| Smartphone Group | 36.55 |
| Smartphone and Info Group | 28.23 |
The level of child's anxiety will be measure by modified Yale Preoperative Anxiety Scale (m-YPAS). The total score of m-YPAS was calculated according to what was originally proposed by Kain et al. The total scores range from 23,4 until 100. Cut-off scores to classify patients with or without anxiety were: without anxiety (23.4 - 30), with anxiety (> 30). (NCT02246062)
Timeframe: Immediately before entering operation room
| Intervention | units on a scale m-YPAS (Mean) |
|---|---|
| Control Group | 31.88 |
| Info Group | 23.88 |
| Smartphone Group | 25.85 |
| Smartphone and Info Group | 25.93 |
To assess the extent of amnesia 1-3 days postoperatively as measured by 100mm Visual Analog Scale with 0mm being Remember Nothing and 100mm being Remember Everything. (NCT01830881)
Timeframe: 1-3 days postoperatively
| Intervention | mm (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 91.5 |
| Midazolam and Ibuprofen | 61.3 |
Subject nausea will be assessed 30 minutes postoperatively using a 100mm Visual Analog Scale with 0mm being None and 100mm being Worst Imaginable (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | 100-mm visual analog sclae for nausea (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 9.5 |
| Midazolam and Ibuprofen | 3.5 |
Subjects will be asked to rate anxiety prior to starting pelvic exam by marking along a mm Visual Analog Scale, with 0mm being No Anxiety and 100mm being Worst Imaginable Anxiety (NCT01830881)
Timeframe: prior to starting pelvic exam (30-60 minutes after premedication)
| Intervention | mm (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 56.6 |
| Midazolam and Ibuprofen | 45.4 |
Subjects will be asked to rate pain at the time of cervical dilation by marking along a mm Visual Analog Scale, with 0mm being No Pain and 100mm being Worst Imaginable Pain (NCT01830881)
Timeframe: with cervical dilation (30-60 minutes after premedication)
| Intervention | mm (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 73.0 |
| Midazolam and Ibuprofen | 69.3 |
Subject sleepiness will be assessed 30 minutes postoperatively using a 100mm Visual Analog Scale with 0mm being None and 100mm being Worst Imaginable (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 40.1 |
| Midazolam and Ibuprofen | 56.6 |
Subject heart rate will be assessed for the duration of the procedure (NCT01830881)
Timeframe: intraoperatively (30-60 minutes after premedication)
| Intervention | bmp (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 80 |
| Midazolam and Ibuprofen | 78.5 |
Subject vital signs (heart rate) will be assessed 30 minutes postoperatively (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | bpm (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 70.1 |
| Midazolam and Ibuprofen | 72 |
Subject oxygenation status will be assessed for the duration of the procedure (NCT01830881)
Timeframe: intraoperatively (30-60 minutes after premedication)
| Intervention | percent saturation (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 98.3 |
| Midazolam and Ibuprofen | 98.1 |
Subject vital signs (oxygenation saturation) will be assessed 30 minutes postoperatively (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | percent saturation (Mean) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 98.3 |
| Midazolam and Ibuprofen | 98.1 |
Number of patient's who could correctly determine if they received study drug or placebo when asked (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo-cherry Syrup and Ibuprofen | 43 |
| Midazolam and Ibuprofen | 48 |
Subjects will be assessed 30 minutes postoperatively for need of additional pain medications. (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Ondansetron | Hydrocodone/acetaminophen | |
| Midazolam and Ibuprofen | 3 | 2 |
| Placebo-cherry Syrup and Ibuprofen | 2 | 1 |
To assess whether oral midazolam is associated with differences in overall patient satisfaction with pain and anxiety control and abortion experience at 30 min postoperatively as measured by a mm Visual Analog Scale with 0mm being Not At All Satisfied and 100mm being Very Satisfied (NCT01830881)
Timeframe: 30 minutes post-operatively
| Intervention | mm on a 100 mm Visual Analog Scale (Mean) | |
|---|---|---|
| Satisfaction with anxiety control (100-mm VAS) | Satisfaction with pain control (100-mm VAS) | |
| Midazolam and Ibuprofen | 68.9 | 50.0 |
| Placebo-cherry Syrup and Ibuprofen | 56.1 | 43.2 |
"To measure the mean State-Trait Anxiety Inventory (STAI) Form Y-1 for anxiety. State anxiety items include: I am tense; I am worried and I feel calm; I feel secure. Trait anxiety items include: I worry too much over something that really doesn't matter and I am content; I am a steady person. Each type of anxiety has its own 4-point scale of 20 different questions that are scored. The 4-point scale for S-anxiety is as follows: 1.) not at all, 2.) somewhat, 3.) moderately so, 4.) very much so. The 4-point scale for T-anxiety is as follows: 1.) almost never, 2.) sometimes, 3.) often, 4.) almost always. Scores range from 20 to 80, with higher scores indicate greater anxiety. State anxiety items and Trait anxiety items were each summed in assessment to provide two total scores for each participant, a State anxiety score and a Trait anxiety score. Mean and standard deviation of total scores for each group are reported." (NCT01830881)
Timeframe: Baseline (upon entry into study)
| Intervention | units on a scale (Mean) | |
|---|---|---|
| State anxiety level | Trait anxiety level | |
| Midazolam and Ibuprofen | 51.3 | 38.6 |
| Placebo-cherry Syrup and Ibuprofen | 50.8 | 40.1 |
Subjects will be asked to rate their anticipated anxiety and pain at the time of uterine aspiration by marking along a mm Visual Analog Scale, with 0mm being No Pain/Anxiety and 100mm being Worst Imaginable Pain/Anxiety (NCT01830881)
Timeframe: Baseline (upon entry into study)
| Intervention | mm (Mean) | |
|---|---|---|
| Expected Anxiety | Expected Pain | |
| Midazolam and Ibuprofen | 74.2 | 69.2 |
| Placebo-cherry Syrup and Ibuprofen | 77.5 | 67.2 |
To assess the extent of amnesia 30 min postoperatively as measured by ability to recall procedure using 4-point scale (0 = unable to recall any proportion of the procedure, 1 = able to recall and describe some portions of the procedure, but overall has minimal recall of the procedure, 2 = able to recall and describe most of the procedure, but admits to inability to recall some portion of the procedure, 3 = able to recall and describe the entire procedure). (NCT01830881)
Timeframe: 30 minutes postoperatively
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Partial to complete amnesia (score 0,1,2) | No Amnesia (score 3) | |
| Midazolam and Ibuprofen | 31 | 30 |
| Placebo-cherry Syrup and Ibuprofen | 16 | 45 |
Subject extent of sedation 30-60 minutes after premedication, just prior to procedure as measured by the 6-point Ramsay Scale (1 = patient anxious agitated, or restless; 2 = patient cooperative, oriented, and tranquil; 3 = patient asleep, responds to commands only; 4 = patient asleep, responds to gentle shaking, light glabellar tap, or loud auditory stimulus; 5 = patient asleep, responds to noxious stimuli such as firm nail bed pressure; 6 = patient asleep, has no response to firm nail bed pressure or other noxious stimuli) (NCT01830881)
Timeframe: 30-60 minutes after premedication
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 or greater | |
| Midazolam and Ibuprofen | 10 | 51 | 1 | 0 |
| Placebo-cherry Syrup and Ibuprofen | 11 | 50 | 0 | 0 |
Subjects will be asked to rate anxiety and pain at the time of uterine aspiration by marking along a 100 mm Visual Analog Scale, with 0mm being No Pain/Anxiety and 100mm being Worst Imaginable Pain/Anxiety (NCT01830881)
Timeframe: at time of uterine aspiration (30-60 minutes after premedication)
| Intervention | mm (Mean) | |
|---|---|---|
| Pain with Aspiration | Anxiety with Aspiration | |
| Midazolam and Ibuprofen | 70.1 | 60.9 |
| Placebo-cherry Syrup and Ibuprofen | 74.3 | 68.2 |
Subjects will be asked to rate anxiety and pain 30 minutes post-operatively by marking along a mm Visual Analog Scale, with 0mm being No Pain/Anxiety and 100mm being Worst Imaginable Pain/Anxiety (NCT01830881)
Timeframe: 30 minutes post operatively
| Intervention | mm (Mean) | |
|---|---|---|
| Anxiety Post Procedure | Pain Post Procedure | |
| Midazolam and Ibuprofen | 14.4 | 37.1 |
| Placebo-cherry Syrup and Ibuprofen | 20.9 | 34.7 |
Subjects will be asked to rate anxiety and pain upon entering procedure room by marking along a mm Visual Analog Scale, with 0mm being No Pain/Anxiety and 100mm being Worst Imaginable Pain/Anxiety (NCT01830881)
Timeframe: upon entering procedure room (30-60 minutes after premedication)
| Intervention | mm (Mean) | |
|---|---|---|
| Anxiety at Room Entry | Pain at Room Entry | |
| Midazolam and Ibuprofen | 34.5 | 10.1 |
| Placebo-cherry Syrup and Ibuprofen | 51.4 | 17.5 |
To assess whether oral midazolam is associated with differences in overall patient satisfaction with pain and anxiety control and abortion experience at 1-3 days postoperatively as measured by a mm VAS with 0mm being Not At All Satisfied and 100mm being Very Satisfied (NCT01830881)
Timeframe: 1-3 days post-operatively
| Intervention | mm on a 100 mm Visual Analog Scale (Mean) | |
|---|---|---|
| Satisfaction with anxiety control (100-mm VAS) | Satisfaction with pain control (100-mm VAS) | |
| Midazolam and Ibuprofen | 64.7 | 48.2 |
| Placebo-cherry Syrup and Ibuprofen | 50.2 | 36.6 |
"Level of sedation at separation from parents and at the time of mask induction will be measured on a scale of 0 to 4 (University of Michigan Sedation Scale)~University of Michigan Sedation Scale:~0 -Awake/Alert~1 -Minimally Sedated: Tired/sleepy, appropriate response to verbal conversation and/or sounds.~2- Moderately Sedated: Somnolent/sleeping, easily aroused with light tactile stimulation.~3 - Deeply Sedated: Deep sleep, arousable only with significant physical stimulation.~4 - Unarousable~Moderately and Deeply sedated: Satisfactory Awake, minimally sedate, unarousable: Unsatisfactory" (NCT02250703)
Timeframe: Day 0:Just before the patient will be brought to the operating room
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Satisfactory sedation on separation from parents | Unsatisfactory sedation on separation from parents | Satisfactory sedation on transfer to OR table | Unsatisfactory sedation on transfer to OR table | |
| Dexmedetomidine | 25 | 11 | 22 | 14 |
| Midazolam | 15 | 22 | 12 | 25 |
Dose of propofol needed for loss of response to verbal command was noted at the time of induction of general anesthesia. The lesser the propofol needed for the loss of response to verbal command, the better the outcome. (NCT01486615)
Timeframe: 1 - 2 hour after premedication
| Intervention | mg (Mean) |
|---|---|
| Melatonin | 79.2 |
| Melatonin and Alprazolam | 65.5 |
| Alprazolam | 59.0 |
| Placebo | 75.8 |
VAS (Visual Analogue Score) Anxiety Scale is a 10 cm long scale with two sides, the patient side (front) and the clinicians side (back). The extremes of the front are colored as white and black with a gradual darkening of color from white to black. The back is marked in centimeter from 0 to 10 and 0 correlates with white color (no anxiety at all) and 10 correlates to black color (anxiety as bad as ever can be) on the front. As anxiety is worsened, the color is darker and score is more. The maximum score is 10 and minimum 0. The patient is asked to point on the scale according to his anxiety level. The anxiety score is the correlating number on the clinicians side. The more the reduction in anxiety from baseline, the better the outcome. (NCT01486615)
Timeframe: Change from baseline in VAS anxiety score at 15 minutes after premedication
| Intervention | Centimeter (Mean) |
|---|---|
| Melatonin | 0.35 |
| Melatonin and Alprazolam | 0.70 |
| Alprazolam | 0.65 |
| Placebo | 0.25 |
VAS (Visual Analogue Score) Anxiety Scale is a 10 cm long scale with two sides, the patient side (front) and the clinicians side (back). The extremes of the front are colored as white and black with a gradual darkening of color from white to black. The back is marked in centimeter from 0 to 10 and 0 correlates with white color (no anxiety at all) and 10 correlates to black color (anxiety as bad as ever can be) on the front. As anxiety is worsened, the color is darker and score is more. The maximum score is 10 and minimum 0. The patient is asked to point on the scale according to his anxiety level. The anxiety score is the correlating number on the clinicians side. The more the reduction in anxiety from baseline, the better the outcome. (NCT01486615)
Timeframe: Changes from baseline in VAS anxiety score at 30 minutes after premedication
| Intervention | centimeter (Mean) |
|---|---|
| Melatonin | 1.15 |
| Melatonin and Alprazolam | 1.72 |
| Alprazolam | 1.62 |
| Placebo | 0.82 |
VAS (Visual Analogue Score) Anxiety Scale is a 10 cm long scale with two sides, the patient side (front) and the clinicians side (back). The extremes of the front are colored as white and black with a gradual darkening of color from white to black. The back is marked in centimeter from 0 to 10 and 0 correlates with white color (no anxiety at all) and 10 correlates to black color (anxiety as bad as ever can be) on the front. As anxiety is worsened, the color is darker and score is more. The maximum score is 10 and minimum 0. The patient is asked to point on the scale according to his anxiety level. The anxiety score is the correlating number on the clinicians side. The more the reduction in anxiety from baseline, the better the outcome. (NCT01486615)
Timeframe: Changes from baseline in VAS anxiety score at one hour after premedication
| Intervention | Centimeter (Mean) |
|---|---|
| Melatonin | 1.80 |
| Melatonin and Alprazolam | 2.92 |
| Alprazolam | 2.35 |
| Placebo | 0.85 |
Number of patients who recalled or recognized the picture number five shown one hour after premedication. The more the number of patients with intact memory, the better the outcome. (NCT01486615)
Timeframe: 24 hour after surgery
| Intervention | Participants (Number) |
|---|---|
| Melatonin | 13 |
| Melatonin and Alprazolam | 4 |
| Alprazolam | 5 |
| Placebo | 14 |
Patients were asked whether they recalled the event of being transferred to the operating room before anaesthesia. The lesser the number of patients with amnesia, the better the outcome. (NCT01486615)
Timeframe: 24 hour after surgery
| Intervention | Participants (Number) |
|---|---|
| Melatonin | 1 |
| Melatonin and Alprazolam | 5 |
| Alprazolam | 4 |
| Placebo | 0 |
Orientation was assessed with a 3 point scale (0=none, 1=orientation in either time or place, 2=orientation in both). Minimum score is 0 and maximum is 2. The lesser the score, the lesser the effect on patients cognition and the better the outcome. (NCT01486615)
Timeframe: Orientation score at one hour after premedication
| Intervention | units on a scale (Median) |
|---|---|
| Melatonin | 2 |
| Melatonin and Alprazolam | 2 |
| Alprazolam | 2 |
| Placebo | 2 |
Sedation level was assessed with a 5 point scale (0=alert, 1=arouses to voice, 2=arouses with gentle tactile stimulation, 3=arouses with vigorous tactile stimulation, 4=lack of responsiveness). Minimum score is 0 and Maximum is 4. The lesser the score, the better the outcome. (NCT01486615)
Timeframe: Sedation score at 1 hour after the premedication
| Intervention | units on a scale (Median) |
|---|---|
| Melatonin | 0.5 |
| Melatonin and Alprazolam | 1 |
| Alprazolam | 1 |
| Placebo | 0 |
Maternal breastfeeding means: exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At the first follow-up visit (7-15 days after discharge)
| Intervention | participants (Number) |
|---|---|
| Control | 32 |
| Music Therapy | 42 |
Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At 30 days after the infant hospital discharge
| Intervention | participants (Number) |
|---|---|
| Control | 30 |
| Music Therapy | 38 |
Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At 60 days after the infant hospital discharge
| Intervention | participants (Number) |
|---|---|
| Control | 27 |
| Music Therapy | 36 |
Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At the time of the infant hospital discharge
| Intervention | participants (Number) |
|---|---|
| Control | 33 |
| Music Therapy | 42 |
Children's behavior during sedation is rated on the Houpt Behavior Rating Scale. A successful sedation is rated as Excellent, Very Good, or Good. A failed sedation is rated as Fair, Poor, or Aborted. (NCT04068948)
Timeframe: At completion of procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam, Hydroxyzine, Meperidine | 11 |
| Midazolam, Hydroxyzine | 9 |
Hypoxia defined as peripheral blood oxygen saturation measured by pulse oxymeter < 90% (NCT02027311)
Timeframe: Every 5min in Preoperative, intraoperative phase and 15 min in Recovery phase
| Intervention | Hypoxia events (Number) |
|---|---|
| Midazolam | 19 |
| Etomidate | 27 |
The frequency of intervention which was defined as any restraint of the patient's head, arms, or legs if they became agitated, or if patient movement was not controlled with verbal instruction from the endoscopist during the whole intraoperative phases. (NCT02027311)
Timeframe: Throughout the whole ERCP procedure
| Intervention | Number of intervention (Mean) |
|---|---|
| Etomidate | 1.9 |
| Midazolam | 7.5 |
Time to cecum (clock display on monitor), faster insertion is a quality marker (NCT03160859)
Timeframe: Insertion time in minutes was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Minutes (Mean) |
|---|---|
| Control Method | 18.8 |
| Study Method | 18.6 |
Proportion of patients who report no pain during insertion of the colonoscope. (NCT03160859)
Timeframe: Pain was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Method | 38 |
| Study Method | 41 |
Pain during insertion reported to the unblinded assisting nurse, visual analogue scale, VAS: 0=none, 10=most severe. The highest pain score will be tabulated for analysis. Timing of data collection will be at the discretion of the nurse to minimize bias by colonoscopist behavior. (NCT03160859)
Timeframe: Insertion pain was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | score on a scale (Mean) |
|---|---|
| Control Method | 2.6 |
| Study Method | 2.9 |
Right colon Adenoma Detection Rate (ADR) is the proportion of patients with at least one adenoma in the part of the colon between the cecum and the hepatic flexure. (NCT03160859)
Timeframe: Adenoma Detection Rate (ADR) was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Method | 40 |
| Study Method | 27 |
describe the adverse events experienced by study participants secondary to sedation medication and interventions performed to overcome them (NCT02518919)
Timeframe: during procedure until discharge from the Emergency Department
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard | 4 |
| Music Listening | 8 |
| Child Life Intervention | 5 |
compare the need for additional dosages of sedation medication among three groups (NCT02518919)
Timeframe: during procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Standard | 9 |
| Music Listening | 4 |
| Child Life Intervention | 8 |
Total mg/kg of sedation medication administered IV (NCT02518919)
Timeframe: Right at the end of the procedure
| Intervention | mg/kg (Mean) |
|---|---|
| Standard | 1.58 |
| Music Listening | 1.68 |
| Child Life Intervention | 1.42 |
Compare consultant satisfaction among three groups using Likert scale (NCT02518919)
Timeframe: within two hours of completion of procedure
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Not satisfied | Satisfied | Very Satisfied | |
| Child Life Intervention | 0 | 6 | 13 |
| Music Listening | 0 | 8 | 12 |
| Standard | 0 | 13 | 7 |
"compare sedation efficacy among the 3 groups using Ramsey sedation scales and FACES -P (FACES-Pediatric)scale. The Ramsey sedation scales scores sedation at six different levels, according to how arousable the patient is. The continuum of sedation is measured from 1-6 with higher values representing a deeper level of sedation.~Patient is anxious and agitated or restless, or both~Patient is co-operative, oriented, and tranquil~Patient responds to commands only~Patient exhibits brisk response to light glabellar tap or loud auditory stimulus~Patient exhibits a sluggish response to light glabellar tap or loud auditory stimulus~Patient exhibits no response The Faces- PScale is a self-report measure used to assess the intensity of children's pain. The scale ranges from 0 to 10 with 0 indicating no hurt or discomfort to 10 :hurts most/worst" (NCT02518919)
Timeframe: During the Procedure
| Intervention | scores on a scale (Median) | |
|---|---|---|
| Ramsay Sedation Score during sedation | FACES-Pediatric during sedation | |
| Child Life Intervention | 6 | 0 |
| Music Listening | 6 | 0 |
| Standard | 6 | 0 |
15 reviews available for midazolam and Anxiety
| Article | Year |
|---|---|
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Melatonin for preoperative and postoperative anxiety in adults.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Anxiety; Bias; Clonidine; Drug Admi | 2020 |
Midazolam for sedation before procedures in adults and children: a systematic review update.
Topics: Administration, Intranasal; Adult; Anxiety; Child; Chloral Hydrate; Humans; Midazolam | 2021 |
Intranasal drug administration for procedural sedation in children admitted to pediatric Emergency Room.
Topics: Administration, Intranasal; Anxiety; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; K | 2018 |
Intranasal drug administration for procedural sedation in children admitted to pediatric Emergency Room.
Topics: Administration, Intranasal; Anxiety; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; K | 2018 |
Intranasal drug administration for procedural sedation in children admitted to pediatric Emergency Room.
Topics: Administration, Intranasal; Anxiety; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; K | 2018 |
Intranasal drug administration for procedural sedation in children admitted to pediatric Emergency Room.
Topics: Administration, Intranasal; Anxiety; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; K | 2018 |
Dexmedetomidine vs midazolam as preanesthetic medication in children: a meta-analysis of randomized controlled trials.
Topics: Anxiety; Child; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Postoperative Complicat | 2015 |
The anxiolytic effect of midazolam in third molar extraction: a systematic review.
Topics: Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Female; Humans; Male; MEDLINE; Midazolam; Mo | 2015 |
Melatonin for pre- and postoperative anxiety in adults.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Clonidine; Drug Administration Schedule; Humans; Melatonin; Mid | 2015 |
Midazolam for sedation before procedures.
Topics: Administration, Intranasal; Administration, Oral; Adult; Anxiety; Child; Chloral Hydrate; Diagnostic | 2016 |
An evidence-based review of parental presence during anesthesia induction and parent/child anxiety.
Topics: Adjuvants, Anesthesia; Anesthesia; Anxiety; Child; Child, Preschool; Evidence-Based Medicine; Humans | 2009 |
The place of premedication in pediatric practice.
Topics: Anesthesia; Anesthetics; Anxiety; Child; Humans; Hypnotics and Sedatives; Midazolam; Pediatrics; Pre | 2009 |
A systematic review of interventions for reducing pain and distress in children undergoing voiding cystourethrography.
Topics: Anesthetics, Inhalation; Anxiety; Child; Fluoroscopy; Hot Temperature; Humans; Hypnotics and Sedativ | 2012 |
Role of nitric oxide in brain regions related to defensive reactions.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Behavior, Animal; Brain; Cats; Cyclic N-Oxides; Dose- | 2005 |
Evidence-based clinical update: does premedication with oral midazolam lead to improved behavioural outcomes in children?
Topics: Administration, Oral; Anesthesia Recovery Period; Anxiety; Child; Child Behavior; Evidence-Based Med | 2006 |
Prevention and intervention strategies to alleviate preoperative anxiety in children: a critical review.
Topics: Anti-Anxiety Agents; Anxiety; Child; Humans; Midazolam; Parent-Child Relations; Preoperative Care; S | 2007 |
Prevention and intervention strategies to alleviate preoperative anxiety in children: a critical review.
Topics: Anti-Anxiety Agents; Anxiety; Child; Humans; Midazolam; Parent-Child Relations; Preoperative Care; S | 2007 |
Prevention and intervention strategies to alleviate preoperative anxiety in children: a critical review.
Topics: Anti-Anxiety Agents; Anxiety; Child; Humans; Midazolam; Parent-Child Relations; Preoperative Care; S | 2007 |
Prevention and intervention strategies to alleviate preoperative anxiety in children: a critical review.
Topics: Anti-Anxiety Agents; Anxiety; Child; Humans; Midazolam; Parent-Child Relations; Preoperative Care; S | 2007 |
The use of midazolam in premedication.
Topics: Anxiety; Diazepam; Half-Life; Humans; Midazolam; Obesity; Postoperative Period; Preanesthetic Medica | 1990 |
Use of midazolam hydrochloride in anesthesia.
Topics: Amnesia; Anesthesia; Anxiety; Cardiovascular System; Humans; Midazolam; Premedication; Respiration | 1987 |
173 trials available for midazolam and Anxiety
| Article | Year |
|---|---|
The effect of using tablet computer on surgical stress: A single-blinded randomized controlled trial.
Topics: Anxiety; Child; Child, Preschool; Computers, Handheld; Humans; Male; Midazolam; Parents; Prospective | 2022 |
Serum concentration of oral midazolam as pediatric preanesthetic medication and factors related to the sedation level.
Topics: Administration, Oral; Anesthesia; Anxiety; Child; Child, Preschool; Double-Blind Method; Humans; Hyp | 2022 |
Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety.
Topics: Anxiety; Dental Anxiety; Dentists; Depression; Humans; Midazolam; Professional Role; Stress Disorder | 2023 |
Psychology versus medication for preanesthesia preparation of children: a randomized controlled trial.
Topics: Anesthesia; Anxiety; Child; Humans; Midazolam; Parents; Preanesthetic Medication; Preoperative Care | 2020 |
Painting Therapy versus Anxiolytic Premedication to Reduce Preoperative Anxiety Levels in Children Undergoing Tonsillectomy: A Randomized Controlled Trial.
Topics: Anti-Anxiety Agents; Anxiety; Child; Double-Blind Method; Humans; Midazolam; Premedication; Tonsille | 2021 |
Which is good for pre-operative anxiety? Midazolam, video games or teaching with cartoons: A randomised trial.
Topics: Anxiety; Child; Emergence Delirium; Humans; Midazolam; Prospective Studies; Video Games | 2021 |
Patient Satisfaction Through an Immersive Experience Using a Mobile Phone-Based Head-Mounted Display During Arthroscopic Knee Surgery Under Spinal Anesthesia: A Randomized Clinical Trial.
Topics: Acoustic Stimulation; Administration, Intravenous; Adult; Anesthesia, Spinal; Anxiety; Arthroscopy; | 2021 |
Preoperative anxiety in preschool children: A randomized clinical trial comparing midazolam, clonidine, and dexmedetomidine.
Topics: Anxiety; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics | 2021 |
Computer tablet distraction reduces pain and anxiety in pediatric burn patients undergoing hydrotherapy: A randomized trial.
Topics: Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Burns; Child; Child, Preschool; Computers, Handhel | 2017 |
Premedication with melatonin vs midazolam: efficacy on anxiety and compliance in paediatric surgical patients.
Topics: Administration, Oral; Adolescent; Anesthesia, Intravenous; Anti-Anxiety Agents; Anxiety; Child; Doub | 2017 |
Childhood preoperative anxiolysis: Is sedation and distraction better than either alone? A prospective randomized study.
Topics: Analgesics; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Combined Modality Therapy; Consci | 2017 |
The Effect of Dextromethorphan Premedication on Cough and Patient Tolerance During Flexible Bronchoscopy: A Randomized, Double-blind, Placebo-controlled Trial.
Topics: Analgesics; Anesthetics, Local; Anti-Anxiety Agents; Antitussive Agents; Anxiety; Bronchoscopy; Coug | 2017 |
Effect of ketamine dose on self-rated dissociation in patients with treatment refractory anxiety disorders.
Topics: Adolescent; Anxiety; Anxiety Disorders; Dissociative Disorders; Double-Blind Method; Humans; Ketamin | 2017 |
The effectiveness of transport in a toy car for reducing preoperative anxiety in preschool children: a randomised controlled prospective trial.
Topics: Anesthesia, General; Anxiety; Cardiac Surgical Procedures; Child, Preschool; Female; Heart Defects, | 2018 |
Randomized controlled trial assessing the effectiveness of midazolam premedication as an anxiolytic, analgesic, sedative, and hemodynamic stabilizer.
Topics: Adult; Aged; Analgesia; Anxiety; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Midazolam; M | 2018 |
A comparison of midazolam and zolpidem as oral premedication in children, a prospective randomized double-blinded clinical trial.
Topics: Administration, Oral; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Double-Blind Method; Fe | 2018 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Single-Blinded Randomized Controlled Study on Use of Interactive Distraction Versus Oral Midazolam to Reduce Pediatric Preoperative Anxiety, Emergence Delirium, and Postanesthesia Length of Stay.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiet | 2019 |
Effects of auriculotherapy and midazolam for anxiety control in patients submitted to third molar extraction.
Topics: Anxiety; Auriculotherapy; Double-Blind Method; Humans; Midazolam; Molar, Third | 2019 |
Efficacy of intravenous ketamine treatment in anxious versus nonanxious unipolar treatment-resistant depression.
Topics: Adult; Anxiety; Anxiety Disorders; Depressive Disorder, Major; Depressive Disorder, Treatment-Resist | 2019 |
Premedication With Midazolam or Haloperidol to Prevent Recovery Agitation in Adults Undergoing Procedural Sedation With Ketamine: A Randomized Double-Blind Clinical Trial.
Topics: Administration, Intravenous; Adult; Anxiety; Conscious Sedation; Double-Blind Method; Emergency Serv | 2019 |
Premedication With Midazolam or Haloperidol to Prevent Recovery Agitation in Adults Undergoing Procedural Sedation With Ketamine: A Randomized Double-Blind Clinical Trial.
Topics: Administration, Intravenous; Adult; Anxiety; Conscious Sedation; Double-Blind Method; Emergency Serv | 2019 |
Premedication With Midazolam or Haloperidol to Prevent Recovery Agitation in Adults Undergoing Procedural Sedation With Ketamine: A Randomized Double-Blind Clinical Trial.
Topics: Administration, Intravenous; Adult; Anxiety; Conscious Sedation; Double-Blind Method; Emergency Serv | 2019 |
Premedication With Midazolam or Haloperidol to Prevent Recovery Agitation in Adults Undergoing Procedural Sedation With Ketamine: A Randomized Double-Blind Clinical Trial.
Topics: Administration, Intravenous; Adult; Anxiety; Conscious Sedation; Double-Blind Method; Emergency Serv | 2019 |
The comparison of dexmedetomidine and midazolam premedication on postoperative anxiety in children for hernia repair surgery: A randomized controlled trial.
Topics: Anti-Anxiety Agents; Anxiety; Blood Pressure; Child; Dexmedetomidine; Double-Blind Method; Female; H | 2019 |
Patient-controlled analgesia with inhaled methoxyflurane versus conventional endoscopist-provided sedation for colonoscopy: a randomized multicenter trial.
Topics: Administration, Inhalation; Analgesia, Patient-Controlled; Anesthesia Recovery Period; Anesthetics, | 2013 |
A randomized, double-blind pilot study of dexmedetomidine versus midazolam for intensive care unit sedation: patient recall of their experiences and short-term psychological outcomes.
Topics: Adult; Aged; Anxiety; Conscious Sedation; Critical Care; Depression; Dexmedetomidine; Double-Blind M | 2015 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Anesthesia induction using video glasses as a distraction tool for the management of preoperative anxiety in children.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Inhalation; | 2013 |
Intranasal clonidine vs. midazolam as premedication in children: a randomized controlled trial.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Cloni | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
Tablet-based Interactive Distraction (TBID) vs oral midazolam to minimize perioperative anxiety in pediatric patients: a noninferiority randomized trial.
Topics: Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Female; Heart Rate; Humans; Hypnot | 2014 |
An Evaluation of Oral Midazolam for Anxiety and Pain in First-Trimester Surgical Abortion: A Randomized Controlled Trial.
Topics: Abortion, Induced; Administration, Oral; Adolescent; Adult; Analgesics; Anti-Anxiety Agents; Anxiety | 2015 |
Influences of Different Doses of Midazolam on Mother and Fetus in Fetoscopic Surgery for Twin-to-Twin Transfusion Syndrome.
Topics: Adult; Anesthesia, Obstetrical; Anxiety; Female; Fetal Monitoring; Fetofetal Transfusion; Fetoscopy; | 2015 |
Melatonin versus midazolam premedication in children undergoing surgery: A pilot study.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Intravenous; Anxiety; Child; Child, Preschool; | 2016 |
A randomised, double-blind controlled trial of intranasal midazolam for the palliation of dyspnoea in patients with life-limiting disease.
Topics: Administration, Intranasal; Aged; Anxiety; Double-Blind Method; Drug Delivery Systems; Dyspnea; Fema | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
Double-blind Randomized Controlled Trial of Intranasal Dexmedetomidine Versus Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair in the Emergency Department.
Topics: Administration, Intranasal; Anesthesia; Anti-Anxiety Agents; Anxiety; Child, Preschool; Dexmedetomid | 2016 |
[Effects of intranasal midazolam premedication on inhaled induction of anesthesia with sevoflurane of pediatric patients].
Topics: Administration, Intranasal; Anesthesia; Anesthetics, Inhalation; Anti-Anxiety Agents; Anxiety; Child | 2016 |
Feasibility and clinical benefit of cognitive-behavioral intervention for preparing patients for transesophageal echocardiography.
Topics: Aged; Anxiety; Cognition; Cognitive Behavioral Therapy; Echocardiography, Transesophageal; Female; H | 2016 |
Propofol versus midazolam for premedication: a placebo‑controlled, randomized double‑blinded study.
Topics: Anesthetics, Intravenous; Anxiety; Conscious Sedation; Double-Blind Method; Female; Humans; Hypnotic | 2016 |
Bicarbonate-buffered ropivacaine-mepivacaine solution for medial caruncle anaesthesia.
Topics: Aged; Amides; Anesthetics, Local; Anxiety; Bicarbonates; Buffers; Double-Blind Method; Female; Human | 2017 |
Comparison of oral midazolam with intranasal dexmedetomidine premedication for children undergoing CT imaging: a randomized, double-blind, and controlled study.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2017 |
Comparison of oral midazolam with intranasal dexmedetomidine premedication for children undergoing CT imaging: a randomized, double-blind, and controlled study.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2017 |
Comparison of oral midazolam with intranasal dexmedetomidine premedication for children undergoing CT imaging: a randomized, double-blind, and controlled study.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2017 |
Comparison of oral midazolam with intranasal dexmedetomidine premedication for children undergoing CT imaging: a randomized, double-blind, and controlled study.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2017 |
Comparison of Oral Midazolam With Intravenous Midazolam for Sedation Children During Upper Gastrointestinal Endoscopy.
Topics: Adolescent; Anxiety; Child; Child, Preschool; Conscious Sedation; Double-Blind Method; Endoscopy, Ga | 2016 |
The effect of play distraction on anxiety before premedication administration: a randomized trial.
Topics: Administration, Oral; Anxiety; Child; Child, Preschool; Female; Humans; Hypnotics and Sedatives; Mal | 2017 |
Can quality of recovery be enhanced by premedication with midazolam?: A prospective, randomized, double-blind study in females undergoing breast surgery.
Topics: Adult; Aged; Anesthetics, Intravenous; Anxiety; Breast Neoplasms; Double-Blind Method; Emotions; Fem | 2017 |
Comparison of ease of administration of intranasal midazolam spray and oral midazolam syrup by parents as premedication to children undergoing elective surgery.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Child; Child, Preschool; Elective Surgica | 2017 |
Effects of age and gender on intravenous midazolam premedication: a randomized double-blind study.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anxiety; Blood Pressure; Conscious Sedation; Dose-Res | 2008 |
Effects of age and gender on intravenous midazolam premedication: a randomized double-blind study.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anxiety; Blood Pressure; Conscious Sedation; Dose-Res | 2008 |
Effects of age and gender on intravenous midazolam premedication: a randomized double-blind study.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anxiety; Blood Pressure; Conscious Sedation; Dose-Res | 2008 |
Effects of age and gender on intravenous midazolam premedication: a randomized double-blind study.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anxiety; Blood Pressure; Conscious Sedation; Dose-Res | 2008 |
Clowns for the prevention of preoperative anxiety in children: a randomized controlled trial.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Doubl | 2009 |
Clowns for the prevention of preoperative anxiety in children: a randomized controlled trial.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Doubl | 2009 |
Clowns for the prevention of preoperative anxiety in children: a randomized controlled trial.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Doubl | 2009 |
Clowns for the prevention of preoperative anxiety in children: a randomized controlled trial.
Topics: Anesthesia; Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Doubl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Relaxing music as pre-medication before surgery: a randomised controlled trial.
Topics: Anxiety; Blood Pressure; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middl | 2009 |
Low-dose fentanyl-midazolam combination improves sevoflurane induction in adults.
Topics: Adult; Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Anxiety; Double | 2009 |
Low-dose oral midazolam reduces fear and distress during needle procedures in children with cancer.
Topics: Administration, Oral; Adolescent; Adult; Anxiety; Child; Child, Preschool; Double-Blind Method; Fear | 2009 |
Pre-operative forced-air warming as a method of anxiolysis.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Female; Heating; Humans; Male; Midazolam; Mid | 2009 |
Effect of an educational pamphlet on colon cancer screening: a randomized, prospective trial.
Topics: Anti-Anxiety Agents; Anxiety; Colonic Neoplasms; Colonoscopy; Female; Humans; Male; Meperidine; Mida | 2010 |
Effects of premedication of midazolam or clonidine on perioperative anxiety and pain in children.
Topics: Administration, Oral; Analgesics; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Clonidine; | 2009 |
Oral midazolam for removal of Kirschner wires in the children's orthopaedic outpatient department: a randomized controlled trial.
Topics: Adjuvants, Anesthesia; Administration, Oral; Anti-Anxiety Agents; Anxiety; Bone Wires; Child; Child, | 2010 |
[Quality of premedication and patient satisfaction after premedication with midazolam, clonidine or placebo : Randomized double-blind study with age-adjusted dosage].
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aging; Anesthesia; Anxiety; Blood Gas Analysis; | 2010 |
Efficacy of two oral premedicants: midazolam or a low-dose combination of midazolam-ketamine for reducing stress during intravenous cannulation in children undergoing CT imaging.
Topics: Administration, Oral; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Catheterization, Peri | 2010 |
Parental presence, clowns or sedative premedication to treat preoperative anxiety in children: what could be the most promising option?
Topics: Allied Health Personnel; Ambulatory Surgical Procedures; Anesthesia; Anxiety; Child; Child, Preschoo | 2010 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Intranasal lidocaine and midazolam for procedural sedation in children.
Topics: Administration, Intranasal; Anesthetics, Local; Anxiety; Child, Preschool; Conscious Sedation; Diagn | 2011 |
Middle-ear surgery under sedation: comparison of midazolam alone or midazolam with remifentanil.
Topics: Adult; Anesthetics, Local; Anxiety; Conscious Sedation; Dizziness; Drug Therapy, Combination; Ear, M | 2011 |
The efficacy of oral midazolam for decreasing anxiety in children undergoing voiding cystourethrogram: a randomized, double-blind, placebo controlled study.
Topics: Administration, Oral; Anti-Anxiety Agents; Anxiety; Child, Preschool; Double-Blind Method; Female; H | 2011 |
Low- versus high-dose combination of midazolam-ketamine for oral premedication in children for ophthalmologic surgeries.
Topics: Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blin | 2011 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, Preschool; Dexmedetomidine; | 2012 |
Music during interventional radiological procedures, effect on sedation, pain and anxiety: a randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anxiety; Female; Fentanyl; Humans; Hypnotics | 2012 |
Comparison of the effects of intranasal midazolam versus different doses of intranasal ketamine on reducing preoperative pediatric anxiety: a prospective randomized clinical trial.
Topics: Administration, Intranasal; Anesthesia; Anxiety; Blood Pressure; Child; Child, Preschool; Conscious | 2012 |
The effect of "multiphase sedation" in the course of computed tomography and magnetic resonance imaging on children, parents and anesthesiologists.
Topics: Adult; Anesthesiology; Anxiety; Attitude; Child, Preschool; Deep Sedation; Double-Blind Method; Fema | 2012 |
Effects of the combination of mask preconditioning with midazolam pretreatment on anxiety and mask acceptance during pediatric inhalational induction and postoperative mask fear in children.
Topics: Anxiety; Child; Child, Preschool; Fear; Female; Humans; Male; Masks; Midazolam | 2012 |
A comparison of oral transmucosal fentanyl and oral midazolam for premedication in children.
Topics: Administration, Oral; Analgesics, Opioid; Anesthesia Recovery Period; Anxiety; Child; Child, Prescho | 2002 |
Preoperative alprazolam reduces anxiety in ambulatory surgery patients: a comparison with oral midazolam.
Topics: Administration, Oral; Adult; Alprazolam; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Anxiet | 2002 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
A paediatric trial comparing midazolam/Syrpalta mixture with premixed midazolam syrup (Roche).
Topics: Administration, Oral; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiety; Child, Preschool; Co | 2003 |
Oral premedication with low dose midazolam modifies the immunological stress reaction after the setting of retrobulbar anaesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anti-Anxiety Agents; Anxiety; Double-Blind Method; Femal | 2003 |
Oral high-dose midazolam premedication for infants and children undergoing cardiovascular surgery.
Topics: Administration, Oral; Anesthetics, Intravenous; Anxiety; Cardiovascular Surgical Procedures; Child, | 2003 |
High-dose rectal midazolam for pediatric procedures: a randomized trial of sedative efficacy and agitation.
Topics: Administration, Rectal; Anxiety; Child, Preschool; Conscious Sedation; Dose-Response Relationship, D | 2003 |
High-dose rectal midazolam for pediatric procedures: a randomized trial of sedative efficacy and agitation.
Topics: Administration, Rectal; Anxiety; Child, Preschool; Conscious Sedation; Dose-Response Relationship, D | 2003 |
High-dose rectal midazolam for pediatric procedures: a randomized trial of sedative efficacy and agitation.
Topics: Administration, Rectal; Anxiety; Child, Preschool; Conscious Sedation; Dose-Response Relationship, D | 2003 |
High-dose rectal midazolam for pediatric procedures: a randomized trial of sedative efficacy and agitation.
Topics: Administration, Rectal; Anxiety; Child, Preschool; Conscious Sedation; Dose-Response Relationship, D | 2003 |
Effect of midazolam on anxiety level and pain perception in cataract surgery with topical anesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Anxiety; D | 2004 |
Interactive music therapy as a treatment for preoperative anxiety in children: a randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anxiety; Child; Child, Preschool; Double-Bli | 2004 |
Interactive music therapy as a treatment for preoperative anxiety in children: a randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anxiety; Child; Child, Preschool; Double-Bli | 2004 |
Interactive music therapy as a treatment for preoperative anxiety in children: a randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anxiety; Child; Child, Preschool; Double-Bli | 2004 |
Interactive music therapy as a treatment for preoperative anxiety in children: a randomized controlled trial.
Topics: Ambulatory Surgical Procedures; Anesthesia, Inhalation; Anxiety; Child; Child, Preschool; Double-Bli | 2004 |
Preoperative intravenous midazolam: benefits beyond anxiolysis.
Topics: Adolescent; Adult; Amnesia, Retrograde; Anti-Anxiety Agents; Anxiety; Blood Pressure; Chi-Square Dis | 2004 |
Improving the acceptability of the atrial defibrillator: patient-activated cardioversion versus automatic night cardioversion with and without sedation (ADSAS 2).
Topics: Anxiety; Atrial Fibrillation; Cross-Over Studies; Defibrillators, Implantable; Electric Countershock | 2004 |
Premedication with orally administered midazolam in adults undergoing diagnostic upper endoscopy: a double-blind placebo-controlled randomized trial.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Anxiety; Conscious Sedation; Double-Blind Method; | 2005 |
Premedication in children: hypnosis versus midazolam.
Topics: Abdomen; Anxiety; Behavior; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hypnosis; | 2005 |
Melatonin vs. midazolam premedication in children: a double-blind, placebo-controlled study.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anti-Anxiety Agents; Anxiety; Anxiety, Separatio | 2005 |
Melatonin vs. midazolam premedication in children: a double-blind, placebo-controlled study.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anti-Anxiety Agents; Anxiety; Anxiety, Separatio | 2005 |
Melatonin vs. midazolam premedication in children: a double-blind, placebo-controlled study.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anti-Anxiety Agents; Anxiety; Anxiety, Separatio | 2005 |
Melatonin vs. midazolam premedication in children: a double-blind, placebo-controlled study.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anti-Anxiety Agents; Anxiety; Anxiety, Separatio | 2005 |
Effect of sedation with midazolam or propofol on patient's comfort during cancer chemotherapy infusion: a prospective, randomized, double-blind study in breast cancer patients.
Topics: Adult; Anesthetics, Intravenous; Antineoplastic Agents; Anxiety; Breast Neoplasms; Double-Blind Meth | 2005 |
Pain and anxiety during interventional radiologic procedures: effect of patients' state anxiety at baseline and modulation by nonpharmacologic analgesia adjuncts.
Topics: Adaptation, Psychological; Aged; Analgesia, Patient-Controlled; Analysis of Variance; Anesthetics, I | 2005 |
High levels of impulsivity may contraindicate midazolam premedication in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Anesthesia; Anesthetics, Intravenous; | 2006 |
The effect of premedication on preoperative anxiety.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Female; Gastric Acid | 2005 |
The effect of premedication on preoperative anxiety.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Female; Gastric Acid | 2005 |
The effect of premedication on preoperative anxiety.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Female; Gastric Acid | 2005 |
The effect of premedication on preoperative anxiety.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Female; Gastric Acid | 2005 |
Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety.
Topics: Adult; Aged; Amnesia; Anxiety; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Distraction with a hand-held video game reduces pediatric preoperative anxiety.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Anxiety; Child; Child, Preschool; Female; Human | 2006 |
Low-dose intranasal versus oral midazolam for routine body MRI of claustrophobic patients.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Arousal; Chi-Square Distribution; Conscio | 2007 |
The effect of skin surface warming on pre-operative anxiety in neurosurgery patients.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Combined Modality Therapy; Heating; Humans; M | 2007 |
[Comparison of premedication regimes. A randomized, controlled trial].
Topics: Adrenal Glands; Adult; Anti-Anxiety Agents; Anxiety; Blood Pressure; Clorazepate Dipotassium; Consci | 2007 |
Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children.
Topics: Adrenergic alpha-Agonists; Anesthetics, Intravenous; Anxiety; Blood Pressure; Carbon Dioxide; Child, | 2007 |
Impact of an information video before colonoscopy on patient satisfaction and anxiety - a randomized trial.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anxiety; Audiovisual Aids; Colonoscopy; Con | 2007 |
Premedication in children: a comparison of oral midazolam and oral clonidine.
Topics: Administration, Oral; Analgesics; Anxiety; Child; Child, Preschool; Clonidine; Conscious Sedation; F | 2007 |
The impact of music on postoperative pain and anxiety following cesarean section.
Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anti-Anxiety Agents; Antiemetics; Anxiety; Cesarean | 2007 |
Conscious sedation during endoscopic retrograde cholangiopancreatography: midazolam or midazolam plus meperidine?
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia Recovery Period; Anxiety; Chi-Square Distribution; Ch | 2007 |
Conscious sedation during endoscopic retrograde cholangiopancreatography: midazolam or midazolam plus meperidine?
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia Recovery Period; Anxiety; Chi-Square Distribution; Ch | 2007 |
Conscious sedation during endoscopic retrograde cholangiopancreatography: midazolam or midazolam plus meperidine?
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia Recovery Period; Anxiety; Chi-Square Distribution; Ch | 2007 |
Conscious sedation during endoscopic retrograde cholangiopancreatography: midazolam or midazolam plus meperidine?
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia Recovery Period; Anxiety; Chi-Square Distribution; Ch | 2007 |
Hypnotic analgesia intervention during first-trimester pregnancy termination: an open randomized trial.
Topics: Abortion, Induced; Adolescent; Adult; Anxiety; Female; Fentanyl; Humans; Hypnosis, Anesthetic; Hypno | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Premedication with intramuscular midazolam: a prospective randomized double-blind controlled study.
Topics: Anxiety; Benzodiazepines; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Humans; Hyd | 1982 |
Midazolam versus hydroxyzine as intramuscular premedicant.
Topics: Adolescent; Adult; Amnesia, Retrograde; Anxiety; Atropine; Benzodiazepines; Double-Blind Method; Hum | 1983 |
Ketamine plus midazolam, a most effective paediatric oral premedicant.
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthesia, Inhalation; Anesthetics, Dissociative; Anxi | 1995 |
[Analgesia-sedation for maxillo-facial surgery with midazolam-pentazocine and miazolam-ketamine. Clinical double-blind study of anxiety, analgesia, sedation and amnesia].
Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Amnesia; Analgesia; Anesthesia; Anesth | 1995 |
Premedication with Midazolam (Dormicum) compared with Promethazine, Droperidol and placebo in relieving anxiety using Beck's anxiety inventory.
Topics: Adolescent; Adult; Aged; Anxiety; Blood Pressure; Double-Blind Method; Droperidol; Drug Monitoring; | 1994 |
[Evaluation of midazolam premedication for preoperative anxiolysis].
Topics: Adolescent; Adult; Anxiety; Female; Genital Diseases, Female; Humans; Injections, Intramuscular; Mid | 1994 |
A randomized, controlled trial of oral midazolam and buffered lidocaine for suturing lacerations in children (the SLIC Trial).
Topics: Administration, Oral; Anesthesia, Local; Anxiety; Buffers; Child; Child, Preschool; Double-Blind Met | 1995 |
Intramuscular dexmedetomidine premedication--an alternative to midazolam-fentanyl-combination in elective hysterectomy?
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anxiety; Bloo | 1994 |
Skin conductance responses in patients sedated with midazolam or propofol.
Topics: Acoustic Stimulation; Adult; Aged; Anesthesia, Local; Anxiety; Conscious Sedation; Female; Galvanic | 1994 |
Oral administration of midazolam as a premedicant for paediatric day-case anaesthesia.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Anxiety; Child; Child Behavior Disorders; Chil | 1994 |
Efficacy of rectal midazolam for the sedation of preschool children undergoing laceration repair.
Topics: Administration, Rectal; Anxiety; Child, Preschool; Conscious Sedation; Double-Blind Method; Emergenc | 1994 |
Nasal versus oral midazolam for sedation of anxious children undergoing laceration repair.
Topics: Administration, Intranasal; Administration, Oral; Anxiety; Child; Child, Preschool; Conscious Sedati | 1994 |
A comparison of intranasal sufentanil and midazolam to intramuscular meperidine, promethazine, and chlorpromazine for conscious sedation in children.
Topics: Administration, Intranasal; Anxiety; Child Behavior; Child, Preschool; Chlorpromazine; Conscious Sed | 1994 |
Propofol or midazolam for short-term alterations in sedation.
Topics: Aged; Anesthesia, Intravenous; Anxiety; Blood Pressure; Conscious Sedation; Cooperative Behavior; Do | 1993 |
Efficacy of intranasal midazolam in facilitating suturing of lacerations in preschool children in the emergency department.
Topics: Administration, Intranasal; Anxiety; Child, Preschool; Conscious Sedation; Double-Blind Method; Huma | 1993 |
Comparison of rectal to intranasal administration of midazolam for premedication of children.
Topics: Administration, Intranasal; Administration, Rectal; Anxiety; Chi-Square Distribution; Child; Child, | 1995 |
[Midazolam versus placebo before spinal anesthesia].
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Spinal; Anxiety; Female; Humans; Hypnotics and Sedat | 1995 |
Evaluation of oral midazolam as pre-medication in day care surgery in adult Pakistani patients.
Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Anxiety; Blood Pre | 1995 |
Patient-controlled premedication by i.v. midazolam for ambulatory surgery.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Intravenous; Anti-Anx | 1996 |
Bilateral block: is it safe and more efficient during removal of third molars?
Topics: Absenteeism; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Anxiety; Conscious Sedation; | 1996 |
Oral midazolam premedication for paediatric day case patients.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Anxiety; Child; Child, Preschool; Double-Blind | 1996 |
Parental presence plus oral midazolam decreases frequency of 5% halothane inductions in children.
Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, General; Anxiety; Behavior; Child; Child, P | 1996 |
The use of oral midazolam in accident and emergency to reduce anxiety in children.
Topics: Administration, Oral; Anxiety; Child; Child, Hospitalized; Child, Preschool; Double-Blind Method; Em | 1996 |
[Perioperative physiological and cognitive functions following oral premedication with 3.75 mg midazolam in operations with retrobulbar anesthesia].
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Spinal; Anxiety; Blood Pressure; Carbon Dioxide; C | 1996 |
Conscious sedation for interventional neuroradiology: a comparison of midazolam and propofol infusion.
Topics: Adult; Anesthetics, Intravenous; Anxiety; Attitude of Health Personnel; Cerebrovascular Disorders; C | 1997 |
Music increases satisfaction in elderly outpatients undergoing cataract surgery.
Topics: Aged; Alfentanil; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, Intravenous; Ane | 1997 |
Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients.
Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Conduction; Anxiety; Arthroplasty; Cognition; Conscious Sed | 1997 |
Overnight sedation with midazolam or propofol in the ICU: effects on sleep quality, anxiety and depression.
Topics: Adult; Aged; Anxiety; Critical Care; Depression; Female; Hemodynamics; Humans; Hypnotics and Sedativ | 1996 |
Oral premedication with midazolam in paediatric anaesthesia. Effects on sedation and gastric contents.
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthesia Recovery Period; Anxiety; Child; Child, Pres | 1997 |
Oral midazolam compared with diazepam-droperidol and trimeprazine as premedicants in children.
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthesia Recovery Period; Anesthesia, Inhalation; Ane | 1997 |
Effect of informed consent on anxiety in patients undergoing diagnostic electrophysiology studies.
Topics: Anti-Anxiety Agents; Anxiety; Arrhythmias, Cardiac; Bradycardia; Cardiac Catheterization; Cardiac Ou | 1997 |
Placebo-controlled trial assessing the use of oral midazolam as a premedication to conscious sedation for pediatric endoscopy.
Topics: Administration, Oral; Anxiety; Chi-Square Distribution; Child; Child, Preschool; Conscious Sedation; | 1998 |
Distress at induction of anaesthesia in children. A survey of incidence, associated factors and recovery characteristics.
Topics: Adjuvants, Anesthesia; Adolescent; Age Factors; Anesthesia; Anesthesia Recovery Period; Anti-Anxiety | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Parental presence during induction of anesthesia versus sedative premedication: which intervention is more effective?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Adult; Anesthesia; Anxiety; Anxiety, Separation; B | 1998 |
Low-dose midazolam sedation: an option for patients undergoing serial hepatic venous pressure measurements.
Topics: Anti-Anxiety Agents; Anxiety; Catheterization; Dose-Response Relationship, Drug; Double-Blind Method | 1999 |
Premedication with melatonin: a double-blind, placebo-controlled comparison with midazolam.
Topics: Administration, Sublingual; Adult; Anxiety; Chi-Square Distribution; Double-Blind Method; Evaluation | 1999 |
A double-blind placebo controlled trial of oral midazolam as premedication before flexible sigmoidoscopy.
Topics: Administration, Oral; Anxiety; Blood Pressure; Double-Blind Method; Female; Humans; Hypnotics and Se | 1999 |
Midazolam nasal spray reduces procedural anxiety in children.
Topics: Administration, Intranasal; Adolescent; Aerosols; Anti-Anxiety Agents; Anxiety; Catheterization, Cen | 2000 |
Does adjunctive midazolam reduce recovery agitation after ketamine sedation for pediatric procedures? A randomized, double-blind, placebo-controlled trial.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Anesthetics, Dissociative; Anti-Anxie | 2000 |
Does adjunctive midazolam reduce recovery agitation after ketamine sedation for pediatric procedures? A randomized, double-blind, placebo-controlled trial.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Anesthetics, Dissociative; Anti-Anxie | 2000 |
Does adjunctive midazolam reduce recovery agitation after ketamine sedation for pediatric procedures? A randomized, double-blind, placebo-controlled trial.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Anesthetics, Dissociative; Anti-Anxie | 2000 |
Does adjunctive midazolam reduce recovery agitation after ketamine sedation for pediatric procedures? A randomized, double-blind, placebo-controlled trial.
Topics: Adjuvants, Anesthesia; Adolescent; Anesthesia Recovery Period; Anesthetics, Dissociative; Anti-Anxie | 2000 |
Chloral hydrate versus midazolam for sedation of children for neuroimaging: a randomized clinical trial.
Topics: Anxiety; Child; Child, Preschool; Chloral Hydrate; Conscious Sedation; Double-Blind Method; Female; | 2000 |
A comparison of midazolam, alfentanil and propofol for sedation in outpatient intraocular surgery.
Topics: Aged; Aged, 80 and over; Alfentanil; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesi | 2000 |
Parental presence and a sedative premedicant for children undergoing surgery: a hierarchical study.
Topics: Adult; Anesthesia; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Female; Humans; Male; Mida | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
Attenuation of the preoperative stress response with midazolam: effects on postoperative outcomes.
Topics: Adult; Anesthesia, General; Anxiety; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; M | 2000 |
The comparative dose-response effects of melatonin and midazolam for premedication of adult patients: a double-blinded, placebo-controlled study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Cognition; Conscious Sedation; Dose-Response | 2000 |
The comparative dose-response effects of melatonin and midazolam for premedication of adult patients: a double-blinded, placebo-controlled study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Cognition; Conscious Sedation; Dose-Response | 2000 |
The comparative dose-response effects of melatonin and midazolam for premedication of adult patients: a double-blinded, placebo-controlled study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Cognition; Conscious Sedation; Dose-Response | 2000 |
The comparative dose-response effects of melatonin and midazolam for premedication of adult patients: a double-blinded, placebo-controlled study.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Cognition; Conscious Sedation; Dose-Response | 2000 |
Midazolam: effects on amnesia and anxiety in children.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Double-Blind Method; Female; Humans; | 2000 |
Comparison of midazolam with or without fentanyl for conscious sedation and hemodynamics in coronary angiography.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anxiety; Conscious Sedation; Coronary Angiograph | 2001 |
Sedation for children requiring wound repair: a randomised controlled double blind comparison of oral midazolam and oral ketamine.
Topics: Administration, Oral; Anxiety; Child; Child, Preschool; Conscious Sedation; Dose-Response Relationsh | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Music decreases sedative requirements during spinal anesthesia.
Topics: Adult; Anesthesia, Spinal; Anxiety; Double-Blind Method; Hemodynamics; Humans; Hypnotics and Sedativ | 2001 |
Oral midazolam premedication for day case breast surgery, a randomised prospective double-blind placebo-controlled study.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Anxiety; Breast; Doubl | 2001 |
A comparison of three doses of a commercially prepared oral midazolam syrup in children.
Topics: Administration, Oral; Adolescent; Anesthesia Recovery Period; Anti-Anxiety Agents; Anxiety; Child; C | 2002 |
[Clonidine vs. Midazolam for premedication - comparison of the anxiolytic effect by using the STAI-test].
Topics: Adrenergic alpha-Agonists; Adult; Anti-Anxiety Agents; Anxiety; Clonidine; Female; Humans; Male; Mid | 2002 |
The use of temazepam elixir in surgical dental sedation: a comparison with intravenous midazolam.
Topics: Administration, Oral; Adult; Analysis of Variance; Anesthesia, Dental; Anxiety; Blood Pressure; Cons | 1992 |
Midazolam versus fentanyl as premedication for painful procedures in children with cancer.
Topics: Adolescent; Anxiety; Bone Marrow Examination; Child; Child, Preschool; Conscious Sedation; Double-Bl | 1992 |
Self-administration of midazolam for postoperative anxiety: a double blinded study.
Topics: Adult; Aged; Anxiety; Depression; Double-Blind Method; Female; Humans; Midazolam; Middle Aged; Morph | 1992 |
Oral midazolam is an effective premedication for children having day-stay anaesthesia.
Topics: Administration, Oral; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Inhala | 1992 |
Premedication before elective breast surgery, a comparison between ketobemidone and midazolam.
Topics: Aged; Analgesics, Opioid; Anxiety; Breast; Female; Humans; Injections, Intramuscular; Meperidine; Mi | 1991 |
Efficacy of oral midazolam prior to intravenous sedation for the removal of third molars.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Anesthesia, Intravenous; Anxiety; Blo | 1991 |
A comparison of oral midazolam solution with temazepam as a day case premedicant.
Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Anxiety; Conscious Sedation; Dilatation | 1991 |
Comparative study of midazolam and diazepam in premedication of bronchoscopy.
Topics: Adult; Amnesia; Anxiety; Bronchoscopy; Diazepam; Double-Blind Method; Female; Humans; Male; Midazola | 1991 |
The effect of orally administered diazepam and midazolam on plasma beta-endorphin, ACTH and preoperative anxiety.
Topics: Adrenocorticotropic Hormone; Adult; Affect; Analysis of Variance; Anxiety; beta-Endorphin; Diazepam; | 1991 |
Midazolam premedication for pediatric bone marrow aspiration and lumbar puncture.
Topics: Adolescent; Anxiety; Biopsy, Needle; Double-Blind Method; Humans; Midazolam; Pain; Pilot Projects; P | 1991 |
Midazolam-droperidol premedication for cardiac surgery. A comparison with papaveretum and hyoscine.
Topics: Adult; Aged; Anxiety; Conscious Sedation; Coronary Artery Bypass; Double-Blind Method; Droperidol; H | 1991 |
[The amnesic effects of midazolam in premedication of children].
Topics: Anxiety; Child; Child, Preschool; Double-Blind Method; Female; Humans; Injections, Intramuscular; Ma | 1991 |
Comparison of various physiologic and psychomotor parameters in patients sedated with intravenous lorazepam, diazepam, or midazolam during oral surgery.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Dental; Anesthesia, Local; Anxiety; Blood Press | 1991 |
Paradoxical reactions to rectal midazolam as premedication in children.
Topics: Administration, Rectal; Analysis of Variance; Anxiety; Chi-Square Distribution; Child; Child Behavio | 1990 |
The effect of oral midazolam on anxiety of preschool children during laceration repair.
Topics: Administration, Oral; Anxiety; Child, Preschool; Crying; Double-Blind Method; Emergency Medicine; Fe | 1990 |
Discomfort after outpatient abortion using paracervical block: a comparison between two opioids and one non-opioid drug for premedication.
Topics: Abortion, Induced; Adult; Ambulatory Care; Anesthesia, Local; Anxiety; Female; Humans; Meperidine; M | 1990 |
[Does flumazenil, a benzodiazepine antagonist used during the anesthesia recovery period, have an anxiogenic effect?].
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anxiety; Epinephrine; Flumazenil; Humans; Midazolam; | 1989 |
Double-blind comparison of midazolam and temazepam as oral premedicants for outpatient anaesthesia.
Topics: Adult; Ambulatory Surgical Procedures; Amnesia; Anti-Anxiety Agents; Anxiety; Double-Blind Method; F | 1989 |
A comparison of midazolam and temazepam for premedication of day case patients.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anti-Anxiety Ag | 1988 |
Benzodiazepine premedication in minor day-case surgery: comparison of oral midazolam and temazepam with placebo.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Amnesia; Anesthesia Recovery Period; Anti-A | 1988 |
Intramuscular midazolam premedication in small children. A comparison with papaveretum and hyoscine.
Topics: Anesthesia Recovery Period; Anxiety; Benzodiazepines; Child; Child, Preschool; Clinical Trials as To | 1986 |
I.v. sedation for conservative dentistry. A comparison of midazolam and diazepam.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Local; Anxiety; Benzo | 1986 |
A re-evaluation of the anxiolytic properties of intramuscular midazolam.
Topics: Adolescent; Adult; Aged; Anxiety; Benzodiazepines; Double-Blind Method; Drug Evaluation; Female; Hum | 1986 |
Diazepam, flunitrazepam and midazolam for elective endoscopy--a comparative study.
Topics: Adult; Anxiety; Clinical Trials as Topic; Diazepam; Female; Flunitrazepam; Gastroscopy; Humans; Infu | 1988 |
Intravenous midazolam in oral surgery.
Topics: Adolescent; Adult; Anesthesia, Dental; Anxiety; Female; Hemodynamics; Humans; Infusions, Intravenous | 1987 |
Midazolam versus fentanyl/droperidol and placebo as intramuscular premedicant.
Topics: Adolescent; Adult; Aged; Anxiety; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Dr | 1985 |
Comparison of chloral hydrate and midazolam by mouth as premedicants in children undergoing otolaryngological surgery.
Topics: Administration, Oral; Anesthesia Recovery Period; Anxiety; Child; Child, Preschool; Chloral Hydrate; | 1988 |
Comparison of midazolam by mouth and diazepam i.v. in outpatient oral surgery.
Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anxiety; Clinical T | 1987 |
Premedication for day case surgery. A study of oral midazolam.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; | 1987 |
Double blind comparative study with intrarectal administration of midazolam, intramuscular administration of diazepam and intrarectal administration of diazepam: preliminary results.
Topics: Administration, Rectal; Anxiety; Child; Child, Preschool; Diazepam; Double-Blind Method; Humans; Inf | 1987 |
158 other studies available for midazolam and Anxiety
| Article | Year |
|---|---|
Effects of anxiety on sedation among pediatric patients undergoing esophagogastroduodenoscopy.
Topics: Adolescent; Anxiety; Anxiety Disorders; Child; Endoscopy, Digestive System; Humans; Hypnotics and Se | 2022 |
Retrospective Comparisons of the Efficacy and Safety of Variable dosing of Midazolam with and without Meperidine for Management of Varying Levels of Anxiety of Pediatric Dental Patients: 35 years of Sedation Experience.
Topics: Anxiety; Child; Conscious Sedation; Humans; Hypnotics and Sedatives; Meperidine; Midazolam; Retrospe | 2022 |
Preoperative anxiety level is not associated with postoperative negative behavioral changes in premedicated children.
Topics: Anesthesia; Anxiety; Child; Clonidine; Humans; Midazolam; Postoperative Period | 2023 |
Residual unabsorbed midazolam: a case report.
Topics: Administration, Oral; Anxiety; Anxiety Disorders; Child; Child, Preschool; Humans; Hypnotics and Sed | 2023 |
The ameliorative effect of midazolam on empathy-like behavior in old rats.
Topics: Aged; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Corticosterone; Empathy; Humans; Mida | 2023 |
There seems to be similar control of anxiety with diazepam, midazolam, and nitrous oxide in patients undergoing surgical maxillary third-molar extraction.
Topics: Anesthesia, Dental; Anxiety; Conscious Sedation; Diazepam; Humans; Midazolam; Molar, Third; Nitrous | 2020 |
Comparison of Three Anxiety Management Protocols: Some Unsettled Questions.
Topics: Anxiety; Diazepam; Midazolam; Nitrous Oxide | 2020 |
In Reply.
Topics: Anxiety; Diazepam; Midazolam; Nitrous Oxide; Research Design | 2020 |
Pre-endoscopic tachycardia predicts increased sedation dose and lower adenoma detection rate in patients undergoing endoscopic procedures: a case control study.
Topics: Adenoma; Adult; Aged; Anxiety; Case-Control Studies; Colonoscopy; Endoscopy, Gastrointestinal; Femal | 2020 |
A retrospective cohort study of predictors and interventions that influence cooperation with mask induction in children.
Topics: Anesthesia, General; Anxiety; Child; Humans; Midazolam; Premedication; Retrospective Studies | 2020 |
Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats.
Topics: Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Cues; Fear; Male; Midazolam; Rats; Rats | 2020 |
Safety of Oral Midazolam as a Perioperative Anxiolytic for Outpatient Dermatologic Procedures.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; An | 2020 |
A prospective observational cohort study to evaluate patients' experience during sequential cataract surgery under monitored anesthesia care and topical anesthesia.
Topics: Aged; Anesthesia, Local; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; Awareness; Cataract Extra | 2020 |
Parental Presence during Induction of Anesthesia Improves Compliance of the Child and Reduces Emergence Delirium.
Topics: Anesthesia; Anxiety; Child; Emergence Delirium; Humans; Infant; Midazolam; Parents; Prospective Stud | 2022 |
[Prevalence and causes of pain after cataract surgery: Comparison of 1st and 2nd eyes].
Topics: Administration, Topical; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Anxiety Agents; Anxiety; | 2017 |
Evaluating Clinical Effectiveness and Pharmacokinetic Profile of Atomized Intranasal Midazolam in Children Undergoing Laceration Repair.
Topics: Adjuvants, Anesthesia; Administration, Intranasal; Anxiety; Child; Child, Preschool; Conscious Sedat | 2017 |
[Towards a better use of midazolam in end of life: A survey in a department of medical oncology].
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Checklist; Clinical Decision-Making; Female; France; Guidel | 2017 |
[Intravenous sedation with midazolam and propofol target controlled infusion on patients'perioperative anxiety under the mandibular third molar extraction].
Topics: Anesthesia, Local; Anesthetics, Intravenous; Anxiety; Blood Pressure; Conscious Sedation; Heart Rate | 2017 |
Assessment of Midazolam Sedation in Ultrasound-Guided Percutaneous Biopsy of Peripheral Lung Lesions.
Topics: Aged; Aged, 80 and over; Anxiety; Biopsy, Fine-Needle; Case-Control Studies; Female; Humans; Hypnoti | 2018 |
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Critical Care; Delirium; Dexmedetomidine; Female; Humans; H | 2018 |
Ambulatory colonoscopy under sedoanalgesia in adult patients with and without irritable bowel syndrome: A prospective, cross-sectional, and double-blind comparison.
Topics: Aged; Analgesia; Anxiety; Colonoscopy; Cross-Sectional Studies; Dose-Response Relationship, Drug; Do | 2018 |
Can We Replace Midazolam With Massage Therapy in the Pediatric Cardiac ICU?
Topics: Anxiety; Child; Humans; Hypnotics and Sedatives; Intensive Care Units; Massage; Midazolam; Pain; Pil | 2018 |
Safety and effectiveness of intranasal midazolam and fentanyl used in combination in the pediatric emergency department.
Topics: Administration, Intranasal; Analgesics, Opioid; Anxiety; Child; Child, Preschool; Drug Therapy, Comb | 2019 |
Effects of Repeated Treatment with Midazolam in SHR and SLA16 Rat Strains in the Triple Test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior Rating Scale; Behavior, Animal; Female; Male; Midazo | 2018 |
Replacement of dexmedetomidine loading with midazolam for sedation in elderly patients with spinal anesthesia.
Topics: Administration, Intravenous; Aged; Anesthesia, Spinal; Anxiety; Arthroplasty, Replacement, Knee; Blo | 2018 |
Application of sedation-agitation scale in conscious sedation before bronchoscopy in children.
Topics: Akathisia, Drug-Induced; Anesthesia, Local; Anti-Anxiety Agents; Anxiety; Bronchoscopy; Child; Child | 2019 |
Intranasal Fentanyl and Midazolam for Procedural Analgesia and Anxiolysis in Pediatric Urgent Care Centers.
Topics: Administration, Intranasal; Adolescent; Ambulatory Care; Analgesia; Analgesics, Opioid; Anxiety; Chi | 2020 |
Adultification of Black Children in Pediatric Anesthesia.
Topics: Administration, Oral; Adolescent; Adolescent Behavior; Age Factors; Anesthesia, General; Anti-Anxiet | 2019 |
Melatonin probably reduces anxiety in patients undergoing third-molar surgical extractions but maybe not as much as midazolam.
Topics: Anti-Anxiety Agents; Anxiety; Humans; Hypnotics and Sedatives; Melatonin; Midazolam; Molar, Third; T | 2019 |
Activation of 5-HT1A receptors in the rat basolateral amygdala induces both anxiolytic and antipanic-like effects.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Dark Adapta | 2013 |
[Bach instead of midazolam?].
Topics: Anxiety; Humans; Hypnotics and Sedatives; Midazolam; Music; Preanesthetic Medication; Preoperative C | 2013 |
Genetic markers of a Munc13 protein family member, BAIAP3, are gender specifically associated with anxiety and benzodiazepine abuse in mice and humans.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Behavior, Animal; Diazepam; Female; Humans; | 2013 |
The effects of midazolam and dexmedetomidine infusion on peri-operative anxiety in regional anesthesia.
Topics: Adult; Anesthesia, Conduction; Anxiety; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Humans; | 2013 |
[Use of midazolam in hospitalized patients: analysis of medical practice].
Topics: Aged; Aged, 80 and over; Anxiety; Female; France; Hospitalization; Humans; Hypnotics and Sedatives; | 2013 |
Activation of ERK2 in basolateral amygdala underlies the promoting influence of stress on fear memory and anxiety: influence of midazolam pretreatment.
Topics: Amygdala; Animals; Anxiety; Butadienes; Conditioning, Psychological; Enzyme Inhibitors; Fear; GABA M | 2014 |
A placebo-controlled trial of midazolam as an adjunct to morphine patient-controlled analgesia after spinal surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Double | 2014 |
A placebo-controlled trial of midazolam as an adjunct to morphine patient-controlled analgesia after spinal surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Double | 2014 |
A placebo-controlled trial of midazolam as an adjunct to morphine patient-controlled analgesia after spinal surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Double | 2014 |
A placebo-controlled trial of midazolam as an adjunct to morphine patient-controlled analgesia after spinal surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Double | 2014 |
Midazolam ameliorates the behavior deficits of a rat posttraumatic stress disorder model through dual 18 kDa translocator protein and central benzodiazepine receptor and neurosteroidogenesis.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Carrier Proteins; Disease Models, Anim | 2014 |
The benzodiazepine midazolam acts on the expression of the defensive behavior, but not on the processing of aversive information, produced by exposure to the elevated plus maze and electrical stimulations applied to the inferior colliculus of rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Dose-Response Relationship, Drug; Ele | 2015 |
Refining the anesthesia management of the face-lift patient: lessons learned from 1089 consecutive face lifts.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Androstanols; Anesthesia; Anesthetics, Inhalatio | 2015 |
Midazolam treatment before re-exposure to contextual fear reduces freezing behavior and amygdala activity differentially in high- and low-anxiety rats.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Conditioning, Classical; Corticos | 2015 |
Evaluation of the anxiolytic and antidepressant effects of asiatic acid, a compound from Gotu kola or Centella asiatica, in the male Sprague Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Centella; Depression; Disease Models, | 2015 |
Intranasal midazolam for anxiolysis in closed reduction of nasal fractures in children.
Topics: Administration, Intranasal; Adolescent; Anxiety; Child; Emergency Service, Hospital; Female; Humans; | 2015 |
Relative luminosity in the plus maze upon the exploratory behaviour of female Wistar rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Estrous Cycle; Exploratory Behavior; Female | 2015 |
α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in mice.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Fear; Female; Male; Mice; Mice, | 2015 |
Which colours are seen by the patient during cataract surgery? Results of an intraoperative interview.
Topics: Aged; Anxiety; Color Perception; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Interv | 2016 |
[Analysis of risk factors for emergence agitation in adults undergoing general anesthesia for nasal surgery].
Topics: Adult; Age Factors; Analgesia; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Inhalati | 2015 |
Evaluation of heat hyperalgesia and anxiety like-behaviors in a rat model of orofacial cancer.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Anxiety; Cell Line, Tumor; Facial Neoplasms; Hot Temperatu | 2016 |
Look again at psychedelic drugs.
Topics: Anxiety; Delirium; Depression; Diazepam; Hallucinogens; Haloperidol; Humans; Lorazepam; Midazolam; P | 2016 |
Hemodynamic profile and behavioral characteristics during induction of anesthesia in pediatric patients with attention deficit hyperactivity disorder.
Topics: Adolescent; Amphetamine; Anesthesia; Anti-Anxiety Agents; Anxiety; Attention Deficit Disorder with H | 2017 |
Aversive learning as a mechanism for lack of repeated anxiolytic-like effect in the elevated plus-maze.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Learning; Male; Midazolam; | 2008 |
Communication and child behaviour associated with unwillingness to take premedication.
Topics: Adult; Anxiety; Child; Child Behavior; Child, Preschool; Communication; Dominance-Subordination; Fem | 2008 |
Integrating the open field, elevated plus maze and light/dark box to assess different types of emotional behaviors in one single trial.
Topics: Animals; Anxiety; Behavior, Animal; Behavioral Research; Chlordiazepoxide; Emotions; Escape Reaction | 2008 |
Intra-periaqueductal gray matter injections of midazolam fail to alter anxiety in plus-maze experienced mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Avoidance Learning; Disease Models, Animal | 2008 |
Creating a sedation service for pediatric urodynamics: our experience.
Topics: Anxiety; Child; Conscious Sedation; Credentialing; Drug Monitoring; Fasting; Humans; Hypnotics and S | 2008 |
Predictive factors of non invasive ventilation failure in critically ill children: a prospective epidemiological study.
Topics: Adolescent; Anti-Anxiety Agents; Anxiety; Asthma; Bronchiolitis; Child; Child, Preschool; Critical I | 2009 |
The role of GABA and anxiety in the reconsolidation of conditioned fear.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Bicuculline; Conditioning, Psychological; | 2008 |
[Intranasal midazolam for central venous catheterization of an anxious patient without a peripheral venous access].
Topics: Abscess; Administration, Intranasal; Amnesia, Anterograde; Anti-Anxiety Agents; Anxiety; Catheteriza | 2008 |
Investigation of the anxiolytic effects of luteolin, a lemon balm flavonoid in the male Sprague-Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Drug Therapy, Combination; Flumazenil; GABA Modulators; Luteo | 2009 |
Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test.
Topics: Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Catheterization; | 2009 |
Minimal sedation second dose strategy with intranasal midazolam in an outpatient pediatric echocardiographic setting.
Topics: Administration, Intranasal; Ambulatory Care; Anxiety; Child, Preschool; Conscious Sedation; Dose-Res | 2009 |
Pentylenetetrazole as an unconditioned stimulus for olfactory and contextual fear conditioning in rats.
Topics: Animals; Anxiety; Association Learning; Avoidance Learning; Conditioning, Classical; Discrimination | 2009 |
The anterior cingulate cortex is a target structure for the anxiolytic-like effects of benzodiazepines assessed by repeated exposure to the elevated plus maze and Fos immunoreactivity.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Exploratory Behavior; | 2009 |
[Case of neurocardiogenic syncope with asystole during insertion of epidural catheter].
Topics: Adult; Anesthesia, Epidural; Anesthesia, General; Anxiety; Atropine; Female; Fluid Therapy; Heart Ar | 2009 |
The alarm pheromone in male rats as a unique anxiety model: psychopharmacological evidence using anxiolytics.
Topics: Administration, Inhalation; Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Clonidine; Disease Mod | 2010 |
Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Camellia sinensis; Drug Synergism; Glutamates; Male; Maze Lea | 2009 |
Previous stress exposure enhances both anxiety-like behaviour and p35 levels in the basolateral amygdala complex: modulation by midazolam.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Cell Count; Cyclin-Dependent Kina | 2010 |
Prenatal ethanol exposure attenuates GABAergic inhibition in basolateral amygdala leading to neuronal hyperexcitability and anxiety-like behavior of adult rat offspring.
Topics: Amygdala; Animals; Anxiety; Cornified Envelope Proline-Rich Proteins; Disease Models, Animal; Ethano | 2010 |
The effects of midazolam and D-cycloserine on the release of glutamate and GABA in the basolateral amygdala of low and high anxiety rats during extinction trial of a conditioned fear test.
Topics: Amygdala; Analysis of Variance; Animals; Anxiety; Anxiety Disorders; Conditioning, Classical; Cyclos | 2010 |
Neural inhibition enables selection during language processing.
Topics: Anxiety; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Interneurons; Language; Male; Memor | 2010 |
Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice.
Topics: Animals; Anxiety; Anxiety Disorders; Behavior, Animal; Cells, Cultured; Depressive Disorder; GABA Mo | 2011 |
Editorial comment.
Topics: Administration, Oral; Anti-Anxiety Agents; Anxiety; Child; Humans; Midazolam; Urethra; Urinary Bladd | 2011 |
Evaluation of the anxiolytic properties of myristicin, a component of nutmeg, in the male Sprague-Dawley rat.
Topics: Allylbenzene Derivatives; Animals; Anti-Anxiety Agents; Anxiety; Benzyl Compounds; Dioxolanes; Drug | 2011 |
Allaying anxiety in children: when a funny thing happens on the way to the operating room.
Topics: Anesthesia; Anxiety; Child; Communication; Health Personnel; Humans; Hypnotics and Sedatives; Midazo | 2011 |
[Uncooperative children during induction of anesthesia : theory and practice].
Topics: Adenoidectomy; Age Factors; Anesthesia; Anti-Anxiety Agents; Anxiety; Child; Child Behavior; Child, | 2011 |
Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Male; Midazolam; Neurotra | 2012 |
Intrahippocampal injection of brain-derived neurotrophic factor increases anxiety-related, but not panic-related defensive responses: involvement of serotonin.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Defense Mechanisms; Hippocampus; Male; Maze Lea | 2012 |
Effectiveness of premedication at the time of separation from parent and mask induction in paediatric patients coming for congenital heart disease surgery.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Cardiac Surgical Procedures; Chi-Square Distribution; Child; Ch | 2012 |
Sedation in the ICU.
Topics: Academic Dissertations as Topic; Acute Kidney Injury; Aged; Anxiety; Critical Care; Deep Sedation; D | 2012 |
Case report: an unforeseen peril of parental presence during induction of anesthesia.
Topics: Adult; Anesthesia; Anxiety; Child; Hernia, Umbilical; Humans; Hypnotics and Sedatives; Male; Midazol | 2012 |
Lack of midazolam-induced anxiolysis in the plus-maze Trial 2 is dependent on the length of Trial 1.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Exploratory Behavior; Male; Midazolam; Moto | 2003 |
Effects of chronic ethanol consumption on rat GABA(A) and strychnine-sensitive glycine receptors expressed by lateral/basolateral amygdala neurons.
Topics: Alcoholism; Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Central Nervous System | 2003 |
Parental intervention choices for children undergoing repeated surgeries.
Topics: Anesthesia; Anxiety; Anxiety, Separation; Child; Child, Preschool; Chronic Disease; Female; Humans; | 2003 |
[Flash visual evoked potentials (FVEP) examination under midazolam sedation of non-cooperating children].
Topics: Anxiety; Apoptosis Regulatory Proteins; Calcium-Binding Proteins; Child; Child, Preschool; Evoked Po | 2002 |
The effects of central administration of physostigmine in two models of anxiety.
Topics: Animals; Anxiety; Cholinesterase Inhibitors; Conditioning, Psychological; Dose-Response Relationship | 2003 |
Rat behavior in two models of anxiety and brain [3H]muscimol binding: pharmacological, correlation, and multifactor analysis.
Topics: Analysis of Variance; Animals; Anxiety; Autoradiography; Behavior, Animal; Binding Sites; Brain; Dis | 2003 |
An outcome study comparing intravenous sedation with midazolam/fentanyl (conscious sedation) versus propofol infusion (deep sedation) for aesthetic surgery.
Topics: Adult; Aged; Anesthetics, Intravenous; Anxiety; Conscious Sedation; Female; Fentanyl; Humans; Hypnot | 2003 |
Infusions of midazolam into the medial prefrontal cortex produce anxiolytic effects in the elevated plus-maze and shock-probe burying tests.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Disease Models, Anima | 2004 |
Conscious sedation for endoscopic and non-endoscopic interventional gastrointestinal procedures: meeting patients' expectations, missing the standard.
Topics: Adjuvants, Anesthesia; Aged; Anesthetics, Combined; Anxiety; Conscious Sedation; Endoscopy, Gastroin | 2004 |
Neural correlates of cat odor-induced anxiety in rats: region-specific effects of the benzodiazepine midazolam.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Brain Stem; Cats; Cell Count; Limbic System; Male; Midazo | 2004 |
Anesthetic management of a patient with asystolic spells.
Topics: Androstanols; Anesthesia; Anesthetics, Inhalation; Anti-Anxiety Agents; Anxiety; Bradycardia; Electr | 2004 |
How we do it: management of tracheobronchial foreign bodies in children.
Topics: Algorithms; Anesthetics, Intravenous; Anxiety; Bronchi; Bronchoscopy; Child; Foreign Bodies; Humans; | 2004 |
Differential effects of midazolam and pentylenetetrazole on behavioral repetition and variation.
Topics: Algorithms; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Conditioning, Operant; Convulsa | 2004 |
From oral midazolam to propofol: a perspective.
Topics: Anti-Anxiety Agents; Anxiety; Conscious Sedation; Endoscopy, Gastrointestinal; Humans; Hypnotics and | 2005 |
Effects of midazolam on the expression of conditioned taste aversion in rats.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Conditioning, Psychological; Do | 2005 |
A comparative study with two types of elevated plus-maze (transparent vs. opaque walls) on the anxiolytic effects of midazolam, one-trial tolerance and fear-induced analgesia.
Topics: Analgesia; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Exploratory Behavior; Fear; Male | 2005 |
Anxiolytic-like effects of mGlu1 and mGlu5 receptor antagonists in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Con | 2005 |
Concurrent nociceptive stimulation impairs the anxiolytic effect of midazolam injected into the periaqueductal gray in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Disease Models, Animal; | 2005 |
Age-related qualitative shift in emotional behaviour: paradoxical findings after re-exposure of rats in the elevated-plus maze.
Topics: Aging; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, An | 2005 |
Role of glutamate ionotropic and benzodiazepine receptors in the ventromedial hypothalamic nucleus on anxiety.
Topics: Animals; Anxiety; Exploratory Behavior; Male; Midazolam; Rats; Rats, Wistar; Receptors, GABA-A; Rece | 2005 |
Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Brain; Chromatography, High Pressure Liquid; Dopami | 2005 |
Pain and anxiety: two problems, two solutions.
Topics: Adaptation, Psychological; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Anxiety; Attenti | 2005 |
Antidepressant-like and anxiolytic-like actions of the mGlu5 receptor antagonist MTEP, microinjected into lateral septal nuclei of male Wistar rats.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety; Cond | 2006 |
Localized injections of midazolam into the amygdala and hippocampus induce differential changes in anxiolytic-like motor activity in mice.
Topics: Amygdala; Animals; Anxiety; GABA Modulators; Hippocampus; Male; Mice; Mice, Inbred C57BL; Microinjec | 2006 |
Effects of age and emotionality on the effectiveness of midazolam administered preoperatively to children.
Topics: Aging; Analysis of Variance; Anesthesia; Anxiety; Child; Child, Preschool; Emotions; Ethnicity; Fema | 2007 |
Effects of age and emotionality on the effectiveness of midazolam administered preoperatively to children.
Topics: Aging; Analysis of Variance; Anesthesia; Anxiety; Child; Child, Preschool; Emotions; Ethnicity; Fema | 2007 |
Effects of age and emotionality on the effectiveness of midazolam administered preoperatively to children.
Topics: Aging; Analysis of Variance; Anesthesia; Anxiety; Child; Child, Preschool; Emotions; Ethnicity; Fema | 2007 |
Effects of age and emotionality on the effectiveness of midazolam administered preoperatively to children.
Topics: Aging; Analysis of Variance; Anesthesia; Anxiety; Child; Child, Preschool; Emotions; Ethnicity; Fema | 2007 |
Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Catecholamines; Corti | 2007 |
Investigation of the anxiolytic effects of linalool, a lavender extract, in the male Sprague-Dawley rat.
Topics: Acyclic Monoterpenes; Animals; Anti-Anxiety Agents; Antidotes; Anxiety; Behavior, Animal; Disease Mo | 2008 |
[Anesthetic management in a patient previously diagnosed with takotsubo cardiomyopathy].
Topics: Acute Coronary Syndrome; Aged; Anesthesia, Intravenous; Anesthesia, Spinal; Anesthetics, Intravenous | 2008 |
Inadequate provision of postintubation anxiolysis and analgesia in the ED.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Cohort Studies; Emergency Service, Ho | 2008 |
Caffeine poisoning and lactate rise: an overlooked toxic effect?
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidotes; Anxiety; Caffeine; Central | 2008 |
Clinical assessment of new I.V. sedation agents and techniques.
Topics: Anesthesia, Dental; Anesthesia, Intravenous; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Drug Int | 1984 |
Defeat engenders pentylenetetrazole-appropriate responding in rats: antagonism by midazolam.
Topics: Agonistic Behavior; Animals; Anxiety; Conditioning, Operant; Discrimination, Psychological; Flumazen | 1994 |
The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Flumazenil; Injections; Male; Mid | 1995 |
Ethopharmacological analysis of rat behavior on the elevated plus-maze.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Appetite Depressants; Behavior, Animal; Carbolines; Explorato | 1994 |
Premedication with oral midazolam in children--an assessment of psychomotor function, anxiolysis, sedation and pharmacokinetics.
Topics: Administration, Oral; Affect; Anxiety; Atropine; Child; Child, Preschool; Circumcision, Male; Consci | 1994 |
Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Anxiety; Appetite Depressants; C | 1993 |
Role of resocialization and of 5-HT1A receptor activation on the anxiogenic effects induced by isolation in the elevated plus-maze test.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Exploratory Behavior; Male; Midazolam; Pyrimidines; Rats; Rat | 1993 |
Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Electroconvulsive Therapy; Flumazenil; Humans; Lorazepam; Male; | 1994 |
Conscious sedation of children.
Topics: Anxiety; Child; Conscious Sedation; Emergencies; Fentanyl; Humans; Midazolam; Pain | 1994 |
Midazolam and flumazenil pharmacokinetics and pharmacodynamics following simultaneous administration to human volunteers.
Topics: Adult; Anxiety; Awareness; Flicker Fusion; Flumazenil; Half-Life; Humans; Male; Midazolam; Protein B | 1994 |
Anodyne imagery: an alternative to i.v. sedation in interventional radiology.
Topics: Aged; Analgesia; Anxiety; Conscious Sedation; Female; Fentanyl; Humans; Hypnosis; Imagination; Male; | 1994 |
[The effects of small dose midazolam in patients to reduce the uncomfortable feeling during epidural block procedure].
Topics: Adult; Aged; Anesthesia, Epidural; Anxiety; Female; Humans; Injections, Intravenous; Male; Midazolam | 1994 |
The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines.
Topics: Amygdala; Animals; Anxiety; Avoidance Learning; Brain; Flumazenil; Infusions, Parenteral; Learning; | 1994 |
Aversive and antiaversive effects of morphine in the dorsal periaqueductal gray of rats submitted to the elevated plus-maze test.
Topics: Animals; Anxiety; Dose-Response Relationship, Drug; Electrodes; Exploratory Behavior; Male; Microinj | 1993 |
Behavioral and pharmacological validation of the elevated plus maze constructed with transparent walls.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Convulsants; Exploratory Behavior; Male | 1995 |
Response to intravenous midazolam sedation in general dental practice.
Topics: Adolescent; Adult; Anesthesia, Dental; Anti-Anxiety Agents; Anxiety; Conscious Sedation; Cooperative | 1996 |
Throat spray for upper gastrointestinal endoscopy is quite acceptable to patients.
Topics: Adolescent; Adult; Aerosols; Aged; Aged, 80 and over; Anesthesia, Local; Anxiety; Conscious Sedation | 1996 |
5-HT1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholinesterase; Adrenergic beta-Antagonists; Amygdala; | 1996 |
A five minute experience in the elevated plus-maze alters the state of the benzodiazepine receptor in the dorsal raphe nucleus.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Flumazenil; GABA-A Receptor Agonists; GABA- | 1997 |
[Management of anxious and painful manifestations in pediatric uroradiology].
Topics: Administration, Rectal; Age Factors; Anesthetics, Inhalation; Anti-Anxiety Agents; Anxiety; Child; C | 1997 |
Combination midazolam and droperidol for severe post-ECT agitation.
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Droperidol; Drug Therapy, Combination; Electroco | 1997 |
Sedation with intravenous midazolam in the pediatric intensive care unit.
Topics: Anxiety; Child; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Infant, N | 1997 |
Stimulation of benzodiazepine receptors in the dorsal hippocampus and median raphé reveals differential GABAergic control in two animal tests of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Hippocampu | 1998 |
Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino)tetralin in the elevated T-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents | 1999 |
Patient attitudes toward undergoing colonoscopy without sedation.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Analgesics, Opioid; Anxiety; Attitude; Colonoscopy; | 1999 |
The role of the hippocampus and 5-HT/GABA interaction in the central effects of benzodiazepine receptor ligands.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepinones; Brain; Conflict, Psychological; Dentate Gy | 1999 |
Differential anxiolytic efficacy of a benzodiazepine on first versus second exposure to a predatory odor in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cats; Conditioning, Psychological; Fear; Male; Midazolam; Odo | 1999 |
Midazolam with ketamine: who benefits?
Topics: Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthetics, Dissociative; Anti-Anxiety Agents; A | 2000 |
Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesia; Animals; Anti-Anxiety Agents; Anxiety; | 2000 |
The anxiolytic effects of intra-hippocampal midazolam are antagonized by intra-septal L-glutamate.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Glutamic Acid; Hippocampus; Male; Maze Lear | 2001 |
The effect of anxiety and personality on the pharmacokinetics of oral midazolam.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Anxiety; Area Under Curve; Female; Humans; Male; M | 2001 |
Anxiolysis with oral midazolam in pediatric patients undergoing dermatologic surgical procedures.
Topics: Administration, Oral; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Cohort Studies; Dermato | 2001 |
Topical pharyngeal anesthesia during gastroscopy.
Topics: Anesthesia, Local; Anesthetics, Local; Anxiety; Gastroscopy; Humans; Larynx; Lidocaine; Midazolam; P | 2001 |
Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Central Nervous System | 2002 |
Prior maze experience required to alter midazolam effects in rats submitted to the elevated plus-maze.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Dose-Response Relationship, Drug; Exploratory Behavior; Male; | 2002 |
Dexmedetomidine synergism with midazolam in the elevated plus-maze test in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Drug Synergism; GABA-A Receptor | 1992 |
[The effects of pentazocine, diazepam and midazolam in patients to reduce the uncomfortable feeling during epidural block procedure].
Topics: Adult; Anesthesia, Epidural; Anxiety; Diazepam; Female; Humans; Male; Midazolam; Pain; Pentazocine; | 1992 |
The comparison of benzodiazepine derivatives and serotonergic agonists and antagonists in two animal models of anxiety.
Topics: Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam; Electroshock; Male; Midazolam | 1992 |
Anxiety in rhesus monkey infants in relation to interactions with their mother and other social companions.
Topics: Animals; Animals, Newborn; Anxiety; Behavior, Animal; Carbolines; Female; Humans; Infant, Newborn; M | 1991 |
[Use of flumazenil to reverse the effects of midazolam in children].
Topics: Adolescent; Age Factors; Anxiety; Child; Child, Preschool; Flumazenil; Humans; Hypnotics and Sedativ | 1991 |
Anxiolytic effect of midazolam microinjected into the dorsal periaqueductal grey area of rats.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Drug Synergism; Electric Stimulation; Flum | 1991 |
Effects of benzodiazepine agonist, inverse agonist and antagonist drugs in the mouse staircase test.
Topics: Animals; Anxiety; Behavior, Animal; Carbolines; Flumazenil; Male; Mice; Mice, Inbred ICR; Midazolam; | 1990 |
Precipitation of benzodiazepine withdrawal following sudden discontinuation of midazolam.
Topics: Anxiety; Humans; Jejunostomy; Male; Midazolam; Middle Aged; Morphine; Pneumonia; Postoperative Compl | 1989 |
[Perioperative anxiety behavior of IVF patients and a suitable simplified analgo-sedation procedure in transvaginal follicle puncture].
Topics: Adult; Analgesia; Anesthesia, Intravenous; Anxiety; Arousal; Female; Fentanyl; Fertilization in Vitr | 1989 |
Patient controlled anxiolysis with midazolam.
Topics: Adult; Aged; Anxiety; Female; Humans; Midazolam; Postoperative Complications; Self Administration | 1989 |
Is midazolam a dangerous drug?
Topics: Anxiety; Diazepam; Humans; Lorazepam; Midazolam | 1989 |
Clinical assessment of a new dilution of midazolam hydrochloride for dental sedation.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Intravenous; Anxiety; Benzodiazepines; Female; Hu | 1986 |
Patient-controlled anxiolysis with midazolam.
Topics: Adult; Aged; Anxiety; Female; Humans; Intensive Care Units; Midazolam; Postoperative Period; Self Ad | 1988 |
Midazolam versus butorphanol as local anaesthetic adjuncts in oral surgery. A clinical assessment.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anxiety; Butorphanol; Female; Humans; Male | 1987 |