midazolam has been researched along with Anoxia-Ischemia, Brain in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the seizure response rate to lidocaine in a large cohort of infants who received lidocaine as second- or third-line antiepileptic drug (AED) for neonatal seizures." | 7.83 | Lidocaine response rate in aEEG-confirmed neonatal seizures: Retrospective study of 413 full-term and preterm infants. ( Boylan, GB; de Vries, LS; Groenendaal, F; Hellström-Westas, L; Pressler, RM; Toet, MC; van den Broek, MP; van Rooij, LG; Weeke, LC, 2016) |
| "To investigate the seizure response rate to lidocaine in a large cohort of infants who received lidocaine as second- or third-line antiepileptic drug (AED) for neonatal seizures." | 3.83 | Lidocaine response rate in aEEG-confirmed neonatal seizures: Retrospective study of 413 full-term and preterm infants. ( Boylan, GB; de Vries, LS; Groenendaal, F; Hellström-Westas, L; Pressler, RM; Toet, MC; van den Broek, MP; van Rooij, LG; Weeke, LC, 2016) |
| " Rapid control of status epilepticus with midazolam has been demonstrated in 2 previous studies with complete clinical and electrographic response in neonates who did not respond to phenobarbital and phenytoin." | 3.74 | Successful management of refractory neonatal seizures with midazolam. ( Kosofsky, BE; LaMothe, J; Nangia, S; Sirsi, D; Solomon, GE, 2008) |
| "Phenobarbital is an inducer of cytochrome P450 (CYP) 3A, while midazolam is a CYP3A substrate." | 1.51 | Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia. ( Cools, F; de Haan, TR; Dijk, PH; Dijkman, KP; Egberts, TCG; Favié, LMA; Groenendaal, F; Huitema, ADR; Nuytemans, DHGM; Rademaker, CMA; Rijken, M; Simons, SHP; van Bel, F; van den Broek, MPH; van der Lee, JH; van Heijst, A; van Straaten, HLM; Zecic, A; Zonnenberg, IA, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, MC | 1 |
| Lee, JY | 1 |
| Lee, HF | 1 |
| Chu, KW | 1 |
| Wu, HF | 1 |
| Lee, CW | 1 |
| Lin, CH | 1 |
| Tang, CW | 1 |
| Lin, HC | 1 |
| Favié, LMA | 1 |
| Groenendaal, F | 2 |
| van den Broek, MPH | 1 |
| Rademaker, CMA | 1 |
| de Haan, TR | 1 |
| van Straaten, HLM | 1 |
| Dijk, PH | 1 |
| van Heijst, A | 1 |
| Simons, SHP | 1 |
| Dijkman, KP | 1 |
| Rijken, M | 1 |
| Zonnenberg, IA | 1 |
| Cools, F | 1 |
| Zecic, A | 1 |
| van der Lee, JH | 1 |
| Nuytemans, DHGM | 1 |
| van Bel, F | 1 |
| Egberts, TCG | 1 |
| Huitema, ADR | 1 |
| Selbst, SM | 1 |
| Weeke, LC | 1 |
| Toet, MC | 1 |
| van Rooij, LG | 1 |
| Boylan, GB | 1 |
| Pressler, RM | 1 |
| Hellström-Westas, L | 1 |
| van den Broek, MP | 1 |
| de Vries, LS | 1 |
| Sirsi, D | 1 |
| Nangia, S | 1 |
| LaMothe, J | 1 |
| Kosofsky, BE | 1 |
| Solomon, GE | 1 |
5 other studies available for midazolam and Anoxia-Ischemia, Brain
| Article | Year |
|---|---|
Increased GABAergic inhibitory function against ischemic long-term potentiation in the CA1 region of the hippocampus.
Topics: Animals; CA1 Region, Hippocampal; GABA Modulators; Glucose; Hypoxia-Ischemia, Brain; Long-Term Poten | 2020 |
Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.
Topics: Anticonvulsants; Asphyxia Neonatorum; Drug Interactions; Drug Therapy, Combination; Female; Humans; | 2019 |
Pediatric emergency medicine: legal briefs.
Topics: Accidents, Traffic; Amputation, Surgical; Baseball; Brain Damage, Chronic; Child; Colon; Commitment | 2013 |
Lidocaine response rate in aEEG-confirmed neonatal seizures: Retrospective study of 413 full-term and preterm infants.
Topics: Anticonvulsants; Central Nervous System Infections; Cohort Studies; Electroencephalography; Female; | 2016 |
Successful management of refractory neonatal seizures with midazolam.
Topics: Anticonvulsants; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Female; Humans; | 2008 |