Page last updated: 2024-10-31

midazolam and Anoxemia

midazolam has been researched along with Anoxemia in 103 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices."9.27Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( Chi, P; He, H; Luo, C; Quan, Z; Wang, L, 2018)
"The aim of this study was to evaluate the prevalence of hypoxia related to midazolam sedation during upper gastrointestinal endoscopy."9.14Assessment the effect of midazolam sedation on hypoxia during upper gastrointestinal endoscopy. ( Fakheri, HT; Hosseini, V; Kabirzadeh, A; Kiasari, AZ; Mohammadpour, RA; Nasrollah, A; Shahmohammadi, S; Taghvaii, T, 2010)
"It is not known whether hypoxia, associated with upper gastrointestinal endoscopic procedures when midazolam sedation is used without narcotics, persists into the post-procedure recovery period."9.07The effects of flumazenil on alertness and hypoxia in elderly patients after ERCP. ( Bibbey, D; Green, JR; Haines, DJ, 1992)
"The purpose of this study was to investigate whether increases in gamma-aminobutyric acid (GABA) in the brain stem underlie the ventilatory decline observed during hypoxia in man."7.68Effects of midazolam and flumazenil on ventilation during sustained hypoxia in humans. ( Dorrington, KL; Nagyova, B; Robbins, PA, 1993)
" The incidence of hypoxemia (oxyhemoglobin saturation less than 90%) and apnea (no spontaneous respiratory effort for 15 s) and the ventilatory response to carbon dioxide were evaluated."7.68Frequent hypoxemia and apnea after sedation with midazolam and fentanyl. ( Ashburn, MA; Bailey, PL; East, KA; Moll, JW; Pace, NL; Stanley, TH, 1990)
"Low-dose etomidate combined with oxycodone and midazolam for endoscopic injection sclerotherapy could reduce the incidence of hypoxia without increasing the incidence of complications."5.69Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy. ( Cao, Y; Hao, S; Quan, Z; Yao, J; Zhou, C, 2023)
"The effectiveness and side effects of dexmedetomidine (DEX) in combination with midazolam and propofol have not been comparatively studied in a single clinical trial as sedative agents to general anesthesia before."5.51Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery. ( Gao, Y; Yan, F, 2022)
"Midazolam was administered to 6-week-old BALB/c male mice under hypoxic conditions and pregnant C57BL/6N mice under normoxic conditions."5.42Midazolam inhibits the hypoxia-induced up-regulation of erythropoietin in the central nervous system. ( Daijo, H; Fukuda, K; Harada, H; Kai, S; Matsuyama, T; Tanaka, T; Tatsumi, K, 2015)
"We evaluated the efficacy and gastroenterologist/patient satisfaction of midazolam combined with oxycodone, relative to that of midazolam combined with sufentanil, for anesthesia during endoscopic injection sclerotherapy (EIS) in patients with cirrhosis and esophageal varices."5.27Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices. ( Chi, P; He, H; Luo, C; Quan, Z; Wang, L, 2018)
" However, IPI registration was more effective in reducing the incidence of apnea episodes."5.24Clinical value of the Integrated Pulmonary Index ( Beitz, A; Geist, C; Heringlake, S; Kronshage, T; Meining, A; Müller, M; Pox, CP; Riphaus, A; Schmiegel, W; von Delius, S; Wehrmann, T, 2017)
"Capnography enables the measurement of end-tidal CO2 and thereby the early detection of apnea, prompting immediate intervention to restore ventilation."5.19Capnographic monitoring of propofol-based sedation during colonoscopy. ( Albert, J; Bojunga, J; Filmann, N; Friedrich-Rust, M; Herrmann, E; Kannengiesser, M; Meckbach, Y; Schroeter, H; Trojan, J; Welte, C; Welte, M; Zeuzem, S, 2014)
"Dexmedetomidine led to a more desired level of awaking sedation, shortened the duration of mechanical ventilation and the length of the ICU stay, and further reduced the prevalence of nosocomial infection for NIV sedation in patients with acute cardiogenic pulmonary edema."5.16Dexmedetomidine versus midazolam for the sedation of patients with non-invasive ventilation failure. ( Chen, YS; Huang, Z; Liu, JY; Yang, ZL, 2012)
"Patients scheduled to undergo ESD for early gastric cancer or adenoma were randomly assigned to sedation with midazolam or propofol, and consciousness level was evaluated by bispectral index (BIS) monitoring."5.16Propofol sedation with bispectral index monitoring is useful for endoscopic submucosal dissection: a randomized prospective phase II clinical trial. ( Azuma, M; Higuchi, K; Ishido, K; Katada, C; Koizumi, W; Naruke, A; Sasaki, T; Sato, A; Tanabe, S, 2012)
"The aim of this study was to evaluate the prevalence of hypoxia related to midazolam sedation during upper gastrointestinal endoscopy."5.14Assessment the effect of midazolam sedation on hypoxia during upper gastrointestinal endoscopy. ( Fakheri, HT; Hosseini, V; Kabirzadeh, A; Kiasari, AZ; Mohammadpour, RA; Nasrollah, A; Shahmohammadi, S; Taghvaii, T, 2010)
"Supplemental oxygen did not reduce (or trend toward reducing) the incidence of hypoxia in patients moderately sedated with midazolam and fentanyl."5.12The utility of supplemental oxygen during emergency department procedural sedation and analgesia with midazolam and fentanyl: a randomized, controlled trial. ( Chudnofsky, CR; Deitch, K; Dominici, P, 2007)
" Ventilatory responses to carbon dioxide and to isocapnic hypoxia were determined during four treatment phases: (1) baseline, (2) alfentanil infusion; (3) combined midazolam and alfentanil infusions, and (4) combined alfentanil, midazolam, and "study drug" (consisting of either flumazenil or flumazenil vehicle) infusions."5.08Effect of flumazenil on ventilatory drive during sedation with midazolam and alfentanil. ( Blouin, RT; Conard, PF; Gross, JB; Häussler, J; Zandsberg, S, 1996)
"Pulse oximetry was used to assess the degree of hypoxia observed in patients receiving simple midazolam sedation for removal of lower third molars and compared to that seen in patients receiving a combination sedation technique using nalbuphine and midazolam."5.07Changes in oxygen saturation using two different sedation techniques. ( Boyle, CA; Thomson, PJ; Walton, GM, 1991)
"It is not known whether hypoxia, associated with upper gastrointestinal endoscopic procedures when midazolam sedation is used without narcotics, persists into the post-procedure recovery period."5.07The effects of flumazenil on alertness and hypoxia in elderly patients after ERCP. ( Bibbey, D; Green, JR; Haines, DJ, 1992)
" The following 4 cardiopulmonary complications were assessed: hypoxia, hypotension, arrhythmias, and apnea."4.82Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. ( Khandwala, F; Lopez, R; Qadeer, MA; Vargo, JJ; Zuccaro, G, 2005)
" A significant odds ratio related to decreased SpO2 was observed for age, sex, midazolam and propofol levels, concurrent use of nitrous oxide, cerebral palsy, Down syndrome, and mental retardation."3.79Risk factors with intravenous sedation for patients with disabilities. ( Fukayama, H; Ishikawa, M; Jinno, S; Kohase, H; Kunimori, H; Miwa, Z; Nakamura, Z; Okumura, H; Shimoyama, K; Tamaki, Y; Yoshikawa, F, 2013)
" Anesthesia was provided with an infusion of midazolam, fentanyl, S-ketamine and low concentrations of isoflurane in oxygen."3.74Balanced anesthesia and ventilation strategies for an alpaca (Lama pacos) with an increased anesthetic-risk. ( Jäggin-Schmucker, N; Larenza, MP; Zanolari, P, 2008)
"We conclude that decreased cerebral endothelial ICAM-1 expression in response to activated glial cell compartment by midazolam may decrease post ischaemic brain inflammation and secondary brain injury."3.73Effect of midazolam on in vitro cerebral endothelial ICAM-1 expression induced by astrocyte-conditioned medium. ( Ghori, K; Harmon, D; Shorten, G; Walsh, F, 2006)
"We have studied in eight rabbits the cardiovascular effects of midazolam, propofol and alfentanil with graded hypoxia."3.69Haemodynamic response to simulated haemorrhage in the rabbit: interaction of i.v. anaesthesia and hypoxia. ( Blake, DW; Ludbrook, J; Petring, OU; Van Leeuwen, AF; Ventura, S, 1995)
"The purpose of this study was to investigate whether increases in gamma-aminobutyric acid (GABA) in the brain stem underlie the ventilatory decline observed during hypoxia in man."3.68Effects of midazolam and flumazenil on ventilation during sustained hypoxia in humans. ( Dorrington, KL; Nagyova, B; Robbins, PA, 1993)
" The incidence of hypoxemia (oxyhemoglobin saturation less than 90%) and apnea (no spontaneous respiratory effort for 15 s) and the ventilatory response to carbon dioxide were evaluated."3.68Frequent hypoxemia and apnea after sedation with midazolam and fentanyl. ( Ashburn, MA; Bailey, PL; East, KA; Moll, JW; Pace, NL; Stanley, TH, 1990)
"However, adverse events such as hypoxemia often occur clinically."3.11Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial. ( An, LX; Qi, XR; Sun, JY; Xue, FS; Zhang, K, 2022)
"Intention-to-treat analysis showed hypoxemia incidence was not significantly lower in the additional capnography arm compared with standard monitoring."2.82Capnographic monitoring of midazolam and propofol sedation during ERCP: a randomized controlled study (EndoBreath Study). ( Bajbouj, M; Geist, C; Heringlake, S; Klare, P; Kronshage, T; Meining, A; Reiter, J; Riphaus, A; Schlag, C; Schmid, RM; Schneider, G; von Delius, S; Wagenpfeil, S; Wehrmann, T, 2016)
"Hypoxemia is a surrogate marker for periprocedural endoscopic complications."2.79Propofol versus midazolam in medical thoracoscopy: a randomized, noninferiority trial. ( Grendelmeier, P; Jahn, K; Pflimlin, E; Stolz, D; Tamm, M, 2014)
" Additionally, propofol dosage and overall rate of adverse events in group Cs were lower than those in group Cc."2.78Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy. ( Cao, K; Chen, X; Guo, Q; Jia, Y; Liu, XM; Shen, SR; Tong, LL; Wang, F; Wang, XY; Xiao, DH; Xu, CX; Zou, HF, 2013)
"Patients with liver cirrhosis frequently undergo diagnostic or therapeutic upper GI endoscopy (UGIE), and the liver disease might impair the metabolism of drugs usually administered for sedation."2.76Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl. ( Bonilha, DQ; Brito, JR; Correia, LM; Ferrari, AP; Gomes, GF; Lenz, L; Libera, ED; Nakao, FS; Rohr, MR, 2011)
"Although prolonged hypoxemia (henceforth referred to as hypoxemia) is not uncommon during moderate sedation for endoscopy, there are only sparse data regarding its relationship with medications, endoscopic intubations and ventilation patterns."2.76Hypoxemia during moderate sedation for gastrointestinal endoscopy: causes and associations. ( Dumot, JA; Lopez, AR; Qadeer, MA; Vargo, JJ, 2011)
"Adult patients with head injuries were prospectively enrolled over a 1-year period by using the following inclusion criteria: Glasgow Coma Scale score of 3 to 8, transport time of greater than 10 minutes, and inability to intubate without RSI."2.70Paramedic-performed rapid sequence intubation of patients with severe head injuries. ( Bailey, D; Davis, D; Hoyt, D; Marshall, L; Ochs, M; Rosen, P, 2002)
" There were no other serious adverse events."1.51Computer-Assisted Propofol Sedation for Esophagogastroduodenoscopy Is Effective, Efficient, and Safe. ( Beecher, R; Chiorean, M; Drennan, F; Gluck, M; Koch, J; Kozarek, RA; La Selva, D; Larsen, M; Lin, OS; McCormick, S; Ross, A; Tombs, D; Venu, N; Weigel, W, 2019)
"Midazolam pretreatment did not affect heroin-induced brain hypoxia but potentiated the initial hypothermia induced by heroin."1.51Interactions of benzodiazepines with heroin: Respiratory depression, temperature effects, and behavior. ( Afzal, A; Kiyatkin, EA, 2019)
"Because of recurrence and aggravation of respiratory distress, she now presented at the Department of Thoracic Surgery, and was scheduled for surgery."1.48Anesthetic Management in Tracheal Dilatation for Severe Tracheal Stenosis. ( Ito, K; Iwazaki, M; Kan, T; Kohno, M; Saito, K; Suzuki, T; Tetsu, S; Yamazaki, K, 2018)
"Although shock was more common in patients with variceal bleeding compared to those with non-variceal bleeding, most cases could be controlled without procedure interruption."1.43Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding. ( Eun, CS; Han, DS; Jeon, YC; Jeong, JY; Park, CH; Sohn, JH; Yoo, KS, 2016)
"Midazolam was administered to 6-week-old BALB/c male mice under hypoxic conditions and pregnant C57BL/6N mice under normoxic conditions."1.42Midazolam inhibits the hypoxia-induced up-regulation of erythropoietin in the central nervous system. ( Daijo, H; Fukuda, K; Harada, H; Kai, S; Matsuyama, T; Tanaka, T; Tatsumi, K, 2015)
"High midazolam dose was associated with lower IPI levels during the procedure."1.42The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children. ( Adiv, OE; Garah, J; Rosen, I; Shaoul, R, 2015)
" The non-cardiopulmonary adverse events were procedure-specific and unrelated to sedation."1.40Conscious sedation for upper endoscopy in the gastric bypass patient: prevalence of cardiopulmonary adverse events and predictors of sedation requirement. ( Abu Dayyeh, BK; Jirapinyo, P; Thompson, CC, 2014)
" Major adverse events occurred in four patients (0."1.40Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. ( Beck, S; Friedrich, K; Gotthardt, DN; Heil, FJ; Rex, DK; Scholl, SG; Sieg, A; Stremmel, W, 2014)
" Compared with the control group, a higher dosage of midazolam was administered (P = 0."1.39Risk of sedation for diagnostic esophagogastroduodenoscopy in obstructive sleep apnea patients. ( Cha, JM; Jeun, JW; Joo, KR; Lee, JI; Pack, KM; Shin, HP; Shin, WC, 2013)
" Adverse events were defined as occurrences that warranted intervention and were classified as hypotension, desaturation, bradycardia, hypertension, arrhythmia, aspiration, respiratory depression, vomiting, cardiac arrest, respiratory arrest, angina, hypoglycemia, and/or allergic reaction."1.37Adverse events during monitored anesthesia care for GI endoscopy: an 8-year experience. ( Agostoni, M; Beretta, L; Fanti, L; Gemma, M; Pasculli, N; Testoni, PA, 2011)
"40 of 79 patients (51%) developed hypoxemia, which occurred more frequently in the obese (71%; 10/14) than the nonobese (46%; 30/65) group (P=0."1.35Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients. ( Dumot, JA; Qadeer, MA; Rocio Lopez, A; Vargo, JJ, 2009)
" The current practice of conscious sedation is safe and tolerated well by most adults in our population."1.34Tolerance and safety to colonoscopy with conscious sedation in Malaysian adults. ( Goh, KL; Ma, WT; Mahadeva, S; Quek, KF, 2007)
" We characterize the fasting status of patients receiving procedural sedation and analgesia in a pediatric ED and assess the relationship between fasting status and adverse events."1.32Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003)
"Adverse effects were common; however, serious adverse effects rarely occurred after 25 minutes from the final medication administration."1.32When is a patient safe for discharge after procedural sedation? The timing of adverse effect events in 1367 pediatric procedural sedations. ( Azer, MM; Newman, DH; Pitetti, RD; Singh, S, 2003)
"This syndrome is relatively uncommon and accompanies dyspnea and hypoxemia on changing to a sitting or standing from recumbent position."1.32[Anesthetic management for a patient with platypnea-orthodeoxia syndrome]. ( Kawamoto, K; Terasaki, H; Yoshitake, A, 2004)
"However, severe hypoxemia occurred in some patients, especially if premedication was used."1.28[Is premedication in gastroscopy hazardous?]. ( Herzer, H; Koller, R; Marbet, UA, 1992)
"Fourteen patients developed hypoxemia of less than 60 mm Hg on FIO2 adjusted to 0."1.28Fiberoptic bronchoscopy in ventilated patients. Evaluation of cardiopulmonary risk under midazolam sedation. ( Blanchet, F; Chastre, J; Dreyfuss, D; Fagon, JY; Gibert, C; Guiguet, M; Trouillet, JL, 1990)

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.91)18.7374
1990's33 (32.04)18.2507
2000's24 (23.30)29.6817
2010's38 (36.89)24.3611
2020's5 (4.85)2.80

Authors

AuthorsStudies
Gao, Y1
Yan, F1
Laubscher, LL1
Meyer, LCR1
Laurence, M1
Raath, JP1
Pfitzer, S1
Qi, XR1
Sun, JY1
An, LX1
Zhang, K1
Xue, FS1
Yao, J1
Hao, S1
Zhou, C1
Cao, Y1
Quan, Z2
Cardoso, CG1
Ayer, IM1
Jorge, AT1
Honsho, CS1
Mattos-Junior, E1
Park, CH2
Park, SW1
Hyun, B1
Lee, J1
Kae, SH1
Jang, HJ1
Koh, DH1
Choi, MH1
Hori, Y1
Shimizu, Y1
Aiba, T1
Luo, C1
Chi, P1
Wang, L1
He, H1
Kumar, A1
Kumar, N1
Sinha, C1
Ito, K1
Yamazaki, K1
Kan, T1
Tetsu, S1
Saito, K1
Kohno, M1
Iwazaki, M1
Suzuki, T1
Takakuwa, O1
Oguri, T1
Asano, T1
Fukuda, S1
Kanemitsu, Y1
Uemura, T1
Ohkubo, H1
Takemura, M1
Maeno, K1
Ito, Y1
Niimi, A1
Cabadas Avión, R1
Baluja, A1
Ojea Cendón, M1
Leal Ruiloba, MS1
Vázquez López, S1
Rey Martínez, M1
Magdalena López, P1
Álvarez-Escudero, J1
Lin, OS1
La Selva, D1
Kozarek, RA1
Tombs, D1
Weigel, W1
Beecher, R1
Koch, J1
McCormick, S1
Chiorean, M1
Drennan, F1
Gluck, M1
Venu, N1
Larsen, M1
Ross, A1
Afzal, A1
Kiyatkin, EA1
Döbrönte, Z1
Szenes, M1
Gasztonyi, B1
Csermely, L1
Kovács, M1
Lakatos, L1
Lakner, L1
Mester, G1
Pandur, T1
Patai, A1
Pák, P1
Pécsi, G1
Rácz, I1
Sarang, K1
Stöckert, A1
Székely, A1
Varga Szabó, L1
Cha, JM1
Jeun, JW1
Pack, KM1
Lee, JI1
Joo, KR1
Shin, HP1
Shin, WC1
Xu, CX1
Chen, X1
Jia, Y1
Xiao, DH1
Zou, HF1
Guo, Q1
Wang, F1
Wang, XY1
Shen, SR1
Tong, LL1
Cao, K1
Liu, XM1
Friedrich-Rust, M1
Welte, M1
Welte, C1
Albert, J1
Meckbach, Y1
Herrmann, E1
Kannengiesser, M1
Trojan, J1
Filmann, N1
Schroeter, H1
Zeuzem, S1
Bojunga, J1
Yoshikawa, F1
Tamaki, Y1
Okumura, H1
Miwa, Z1
Ishikawa, M1
Shimoyama, K1
Nakamura, Z1
Kunimori, H1
Jinno, S1
Kohase, H1
Fukayama, H1
Sieg, A1
Beck, S1
Scholl, SG1
Heil, FJ1
Gotthardt, DN1
Stremmel, W1
Rex, DK1
Friedrich, K1
Jirapinyo, P1
Abu Dayyeh, BK1
Thompson, CC1
Grendelmeier, P1
Tamm, M1
Jahn, K1
Pflimlin, E1
Stolz, D1
Hung, A1
Marshall, J1
Barnett, S1
Falchuk, ZM1
Sawhney, M1
Leffler, DA1
Garah, J1
Adiv, OE1
Rosen, I1
Shaoul, R1
Sago, T1
Harano, N1
Chogyoji, Y1
Nunomaki, M1
Shiiba, S1
Watanabe, S1
Dyer, O1
Matsuyama, T1
Tanaka, T1
Tatsumi, K1
Daijo, H1
Kai, S1
Harada, H1
Fukuda, K1
Klare, P1
Reiter, J1
Meining, A3
Wagenpfeil, S2
Kronshage, T2
Geist, C2
Heringlake, S2
Schlag, C1
Bajbouj, M2
Schneider, G2
Schmid, RM2
Wehrmann, T2
von Delius, S3
Riphaus, A2
Han, DS1
Jeong, JY1
Eun, CS1
Yoo, KS1
Jeon, YC1
Sohn, JH1
Pox, CP1
Schmiegel, W1
Beitz, A1
Müller, M1
Ma, WT1
Mahadeva, S1
Quek, KF1
Goh, KL1
Qadeer, MA3
Rocio Lopez, A1
Dumot, JA2
Vargo, JJ3
Awab, A1
Alilou, M1
El Moussaoui, R1
El Hijri, A1
Azzouzi, A1
Kjaergaard, B1
Jakobsen, LK1
Nielsen, C1
Knudsen, PJ1
Kristensen, SR1
Larsson, A1
Cury, AF1
Vieira, ML1
Fischer, CH1
Rodrigues, AC1
Cordovil, A1
Monaco, C1
Naccarato, GA1
Tavares, G1
Lira Filho, EB1
Guimarães, LA1
Morhy, SS1
Gerónimo Pardo, M1
Mateo Cerdán, CM1
Moreno Salcedo, JM1
Fakheri, HT1
Kiasari, AZ1
Taghvaii, T1
Hosseini, V1
Mohammadpour, RA1
Nasrollah, A1
Kabirzadeh, A1
Shahmohammadi, S1
Correia, LM1
Bonilha, DQ1
Gomes, GF1
Brito, JR1
Nakao, FS1
Lenz, L1
Rohr, MR1
Ferrari, AP1
Libera, ED1
Lopez, AR1
Aksu, R1
Kumandas, S1
Akin, A1
Bicer, C1
Gümüş, H1
Güler, G1
Per, H1
Bayram, A1
Boyaci, A1
Agostoni, M1
Fanti, L1
Gemma, M1
Pasculli, N1
Beretta, L1
Testoni, PA1
Schernthaner, A1
Lendl, CE1
Hartmann, K1
Pragst, I1
Preissel, AK1
Henke, J1
Viljoen, A1
Byth, K1
Coombs, M1
Mahoney, G1
Stewart, D1
Salletmaier, H1
Saur, D1
Huber, W1
Sasaki, T1
Tanabe, S1
Azuma, M1
Sato, A1
Naruke, A1
Ishido, K1
Katada, C1
Higuchi, K1
Koizumi, W1
Huang, Z1
Chen, YS1
Yang, ZL1
Liu, JY1
Ferguson, ND1
Cook, DJ1
Guyatt, GH1
Mehta, S1
Hand, L1
Austin, P1
Zhou, Q1
Matte, A1
Walter, SD1
Lamontagne, F1
Granton, JT1
Arabi, YM1
Arroliga, AC1
Stewart, TE1
Slutsky, AS1
Meade, MO1
Ochs, M1
Davis, D1
Hoyt, D1
Bailey, D1
Marshall, L1
Rosen, P1
Chan, PB1
Rekling, JC1
Oku, K1
Yamanaka, T1
Ashihara, N1
Kawasaki, K1
Mizuno, Y1
Fujinaga, T1
Agrawal, D1
Manzi, SF1
Gupta, R1
Krauss, B1
Newman, DH1
Azer, MM1
Pitetti, RD1
Singh, S1
Kawamoto, K1
Yoshitake, A1
Terasaki, H1
Bowdle, TA1
Sanborn, PA1
Michna, E1
Zurakowski, D1
Burrows, PE1
Fontaine, PJ1
Connor, L1
Mason, KP1
Khandwala, F1
Lopez, R1
Zuccaro, G1
Wettstein, D1
Moens, Y1
Jaeggin-Schmucker, N1
Böhm, SH1
Rothen, HU1
Mosing, M1
Kästner, SB1
Schatzmann, U1
Kim, C1
Shvarev, Y1
Takeda, S1
Sakamoto, A1
Lindahl, SG1
Eriksson, LI1
Ghori, K1
Harmon, D1
Walsh, F1
Shorten, G1
Deitch, K1
Chudnofsky, CR1
Dominici, P1
Di Liddo, L1
D'Angelo, A1
Nguyen, B1
Bailey, B1
Amre, D1
Stanciu, C1
Warrillow, S1
Bellomo, R1
Jones, D1
Bleiberg, AH1
Salvaggio, CA1
Roy, LC1
Kassutto, Z1
Melamed, E1
Oron, Y1
Ben-Avraham, R1
Blumenfeld, A1
Lin, G1
Larenza, MP1
Zanolari, P1
Jäggin-Schmucker, N1
Blake, DW1
Van Leeuwen, AF1
Petring, OU1
Ludbrook, J1
Ventura, S1
Patterson, KW1
Noonan, N1
Keeling, NW1
Kirkham, R1
Hogan, DF1
Abrams, R1
Morrison, JE1
Villasenor, A1
Hencmann, D1
Da Fonseca, M1
Mueller, W1
Götell, P1
Yeo, SW1
Tay, D1
Chong, JL1
Tan, TK1
Nagyova, B1
Dorrington, KL1
Robbins, PA1
Torjman, M1
Mora, CT1
White, PF1
Block, R1
Jankowski, J1
Johnston, D1
Colvin, JR1
Wormsley, KG1
Smith, MR1
Bell, GD2
Paul, AB1
Brown, R1
Brewster, N1
Griffiths, JM1
Mak, KH1
Wang, YT1
Cheong, TH1
Poh, SC1
Blouin, RT2
Conard, PF2
Perreault, S1
Gross, JB3
Papageorge, MB1
Hunter, MJ1
Norris, LH1
Rosenberg, MB1
Muñoz, HR1
Dagnino, J1
Zandsberg, S1
Häussler, J1
Kelly, MC1
Loan, WC1
Litman, RS1
Kottra, JA1
Berkowitz, RJ1
Ward, DS2
Kristensen, MS1
Milman, N1
Jarnvig, IL1
Oei-Lim, VL1
Kalkman, CJ1
Bartelsman, JF1
Res, JC1
van Wezel, HB1
Axelrod, FB1
Maayan, C1
Luotio, K2
Mattila, MA2
Kotilainen, RM1
Matthews, RW1
Malkawi, Z1
Griffiths, MJ1
Scully, C1
Noble, WH1
Baker, A1
Haines, DJ2
Bibbey, D2
Green, JR2
Marbet, UA1
Koller, R1
Herzer, H1
Lowe, T1
Brook, IM1
Dahan, A1
Raine, J1
Warner, JO1
Abramowicz, AE1
Kass, IS1
Chambers, G1
Cottrell, JE1
Walton, GM1
Boyle, CA1
Thomson, PJ1
Trouillet, JL1
Guiguet, M1
Gibert, C1
Fagon, JY1
Dreyfuss, D1
Blanchet, F1
Chastre, J1
Bailey, PL1
Pace, NL1
Ashburn, MA1
Moll, JW1
East, KA1
Stanley, TH1
Bown, S1
Morden, A1
Coady, T1
Logan, RF1
Rodrigo, MR1
Rosenquist, JB1
Alexander, CM1

Clinical Trials (30)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Intravenous Lidocaine Reduce Propofol Consumption and the Side Effects of Sedation During Gastroscopy in ASA 1 and 2 Patients.[NCT05944887]46 participants (Actual)Interventional2023-07-21Completed
Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Bronchoscopy Procedures Under Sedation[NCT05137587]60 participants (Actual)Interventional2022-09-01Completed
Comparison of Efficacy and Safety of the Postoperative Analgesia Methods for Supratentorial Craniotomy by Integrated Pulmonary Index (IPI)[NCT02929147]Phase 490 participants (Anticipated)Interventional2016-11-30Not yet recruiting
Importance of Integrated Pulmonary Index in Pediatric Patients Undergoing Endoscopy Procedures Under Sedation[NCT05137574]60 participants (Actual)Interventional2021-05-10Completed
Capnography as an Adjunct to Standard Monitoring During Midazolam and Propofol Sedation for ERCP[NCT01072474]Phase 3242 participants (Anticipated)Interventional2010-02-28Completed
The Value of Integrated Pulmonary Index Monitoring[NCT05356819]154 participants (Actual)Interventional2018-10-01Completed
High Flow Nasal Cannula (HFNC) Versus Standard Low Flow Nasal Cannula (LFNC) in Patients With Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation (RFCA) Under Deep Desaturation.[NCT04842253]210 participants (Anticipated)Interventional2022-01-04Recruiting
Music Utilization in Sedation and Induction in Colonoscopy[NCT04468048]0 participants (Actual)Observational2019-01-30Withdrawn (stopped due to No participants)
High-Flow Nasal Oxygenation Versus Standard Oxygenation in Gastrointestinal Endoscopy With Sedation. A Prospective Multicenter Randomized Study[NCT03829293]380 participants (Actual)Interventional2019-03-26Completed
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
Nasal Inhalation of Sevoflurane Versus Midazolm,Ketamine and Propofol For Pediatric Undergoing Upper Gastrointestinal Endoscopy[NCT05474937]74 participants (Anticipated)Interventional2022-06-01Recruiting
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial[NCT03453359]180 participants (Actual)Interventional2018-01-28Completed
Comparison of Cardio-respiratory Variables Between Low-frequency High Frequency Oscillation With/Without Tracheal Gas Insufflation and High-frequency High-frequency Oscillation in Severe ARDS.[NCT02027129]Phase 117 participants (Actual)Interventional2014-01-31Completed
Early Use of Airway Pressure ReLease Ventilation in Critically Ill Adults With Moderate-to-severe Acute Respiratory Distress Syndrome[NCT04156438]1 participants (Actual)Interventional2020-06-29Completed
The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study[NCT00474656]94 participants (Actual)Interventional2007-06-30Completed
The Oscillation for ARDS Treated Early (OSCILLATE) Trial[NCT01506401]Phase 3548 participants (Actual)Interventional2009-06-30Terminated (stopped due to Enrolment halted by Steering Committee on advice from Data Monitoring Committee.)
Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study[NCT02342756]20 participants (Anticipated)Interventional2015-01-31Active, not recruiting
Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638]240 participants (Anticipated)Interventional2015-10-31Not yet recruiting
Can Medical Clowns Prevent the Usage of Sedation During the Performance of EEG in Young Children[NCT05257096]100 participants (Anticipated)Interventional2019-05-01Recruiting
A Psychomotor Recuperation Study After Deep Sedation for Colonoscopy Between Target Controlled and Manual Titration of Propofol.[NCT02314559]Phase 4164 participants (Actual)Interventional2015-02-28Completed
Effect of High Flow Nasal Cannula vs. Standard Care on Respiratory Stability in Pediatric Procedural Sedation: A Randomized Controlled Pilot Trial[NCT02930525]50 participants (Actual)Interventional2016-09-30Completed
Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915]314 participants (Actual)Observational2017-08-01Completed
A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651]Phase 120 participants (Actual)Interventional2013-02-28Completed
Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients: Impact on Respiratory Mechanics and Gas Exchange[NCT04502368]15 participants (Anticipated)Observational2020-09-01Recruiting
Postoperative Management of Obstructive Sleep Apnea With CPAP vs. an Autoadjusting CPAP Device: a Randomized Controlled Single Center Trial[NCT00588848]11 participants (Actual)Interventional2008-01-31Terminated (stopped due to Difficulty with enrollment)
Dex vs Dazzle: Dexmedetomidine vs Midazolam for Intraoperative Sedation[NCT02878837]Phase 4120 participants (Actual)Interventional2016-01-31Completed
Anesthesia Endoscope Mask is Applied to Sedation Upper Gastrointestinal Endoscopic Diagnosis and Treatment: Multi-center, Prospective, Randomized Control, Open Clinical Research[NCT06085859]1,208 participants (Anticipated)Interventional2023-10-18Recruiting
TAP) Block in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study[NCT01075087]19 participants (Actual)Interventional2010-03-31Completed
The Effect of Systemic Intraoperative Lidocaine on Postoperative Pain and Quality of Recovery on Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery[NCT01180660]51 participants (Actual)Interventional2010-06-30Completed
Influence of Different Anesthetic Procedures on Sleep Disorder Breathing in Adult Patients Undergoing Elective Surgery[NCT03499132]90 participants (Actual)Observational2018-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Apnea-Hypopnea Index (AHI)

Events are defined as apneas and hypopneas. AHI values are typically categorized as 5-14.9 events/hr = mild; 15-29.9 events/hr = moderate; and >= 30 events/hr = severe (NCT00588848)
Timeframe: On postoperative night number 1 from 2200 to 0600. Study participation will end within 72 hours of admission.

Interventionevents per hour (Mean)
AUTOCPAP2.1
CPAP1.2

Cardiopulmonary Complications

Predefined cardiopulmonary complications: Myocardial Infarction, Arrhythmia, new onset Heart Failure, Stroke (NCT00588848)
Timeframe: 72 hours

InterventionParticipants (Count of Participants)
Autoadjusting CPAP (VPAP Auto)0
CPAP Arm (Usual Care)0

Sleep Related Hypoxemia

(NCT00588848)
Timeframe: On postoperative night number 1 from 2200 to 0600. Study participation will end within 72 hours of admission.

InterventionPercentage of time < 90% saturation (Mean)
AUTOCPAP10.5
CPAP7.1

24 Hour Total Opioid Consumption.

24 Hour total opioid consumption translated into IV morphine equivalents. (NCT01075087)
Timeframe: 24 hours

Interventionmiligram IV morphine equivalents (Median)
Placebo13
Active Comparator7.5

Quality of Recovery 40 Score

Quality of Recovery 40 Score at 24 hours postoperative. (NCT01075087)
Timeframe: 24 hours post operatively

Interventionunits on scale 40 (low) - 200 (high) (Median)
Placebo170
Active Comparator175.5

24 Hour Total Opioid Consumption

24 hour total opioid consumption using IV morphine equivalents (NCT01180660)
Timeframe: 24 hours post surgery

Interventionmiligrams (Median)
Lidocaine26
Placebo36

Quality of Recovery 40 on the Day After Surgery

"Quality of Recovery 40 on the Day After Surgery. The survey is a quality of recovery tool and a score of 40 is low and 200 is high.~The minimum score is 40 which is minimum recovery score and them maximum score is 200 which is considered better recovery." (NCT01180660)
Timeframe: 24 hours

Interventionunits on scale 40 (low) - 200 (high) (Median)
Lidocaine165
Placebo146

Reviews

1 review available for midazolam and Anoxemia

ArticleYear
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005
Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:11

    Topics: Apnea; Arrhythmias, Cardiac; Cholangiopancreatography, Endoscopic Retrograde; Colonoscopy; Endoscopy

2005

Trials

38 trials available for midazolam and Anoxemia

ArticleYear
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery.
    Current drug metabolism, 2022, Volume: 23, Issue:1

    Topics: Anesthesia; Apnea; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Hypo

2022
Effects of intravenous lidocaine on hypoxemia induced by propofol-based sedation for gastrointestinal endoscopy procedures: study protocol for a prospective, randomized, controlled trial.
    Trials, 2022, Sep-24, Volume: 23, Issue:1

    Topics: Conscious Sedation; Endoscopy, Gastrointestinal; Humans; Hypotension; Hypoxia; Lidocaine; Midazolam;

2022
Application of low-dose etomidate combined with oxycodone and midazolam in endoscopic injection sclerotherapy.
    International journal of clinical pharmacology and therapeutics, 2023, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Etomidate; Humans; Hypoxia; Midazolam; Middle Age

2023
Efficacy and safety of etomidate-based sedation compared with propofol-based sedation during ERCP in low-risk patients: a double-blind, randomized, noninferiority trial.
    Gastrointestinal endoscopy, 2018, Volume: 87, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retro

2018
Analgesic Effects of Oxycodone Relative to Those of Sufentanil, in the Presence of Midazolam, During Endoscopic Injection Sclerotherapy for Patients With Cirrhosis and Esophageal Varices.
    Anesthesia and analgesia, 2018, Volume: 127, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia; Body Mass Index; Double-Blind Method; Drug Therapy, Com

2018
Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy.
    World journal of gastroenterology, 2013, Aug-07, Volume: 19, Issue:29

    Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Blood Pressure; Chi-Square Distribution; China; Dr

2013
Capnographic monitoring of propofol-based sedation during colonoscopy.
    Endoscopy, 2014, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Apnea; Body Mass Index; Capnography; Colono

2014
Propofol versus midazolam in medical thoracoscopy: a randomized, noninferiority trial.
    Respiration; international review of thoracic diseases, 2014, Volume: 88, Issue:2

    Topics: Aged; Aged, 80 and over; Anesthetics, Intravenous; Deep Sedation; Female; Hemodynamics; Humans; Hypo

2014
A nasal high-flow system prevents hypoxia in dental patients under intravenous sedation.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2015, Volume: 73, Issue:6

    Topics: Adult; Airway Management; Anesthesia, Dental; Anesthetics, Intravenous; Blood Gas Monitoring, Transc

2015
Capnographic monitoring of midazolam and propofol sedation during ERCP: a randomized controlled study (EndoBreath Study).
    Endoscopy, 2016, Volume: 48, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Capnography; Cholangiopancreatography, Endoscopic Retrograde; Consci

2016
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Clinical value of the Integrated Pulmonary Index
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apnea; Capnography; Deep Sedation; Endoscopy, Gastrointestinal; Fema

2017
Assessment the effect of midazolam sedation on hypoxia during upper gastrointestinal endoscopy.
    Pakistan journal of biological sciences : PJBS, 2010, Feb-15, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Endoscopy, Digestive System; Female; Humans; Hypnotics and Sedatives; Hypoxia; Ma

2010
Sedation during upper GI endoscopy in cirrhotic outpatients: a randomized, controlled trial comparing propofol and fentanyl with midazolam and fentanyl.
    Gastrointestinal endoscopy, 2011, Volume: 73, Issue:1

    Topics: Analgesics, Opioid; Anesthesia Recovery Period; Bradycardia; Conscious Sedation; Deep Sedation; Endo

2011
Hypoxemia during moderate sedation for gastrointestinal endoscopy: causes and associations.
    Digestion, 2011, Volume: 84, Issue:1

    Topics: Aged; Anesthetics, Combined; Anesthetics, Intravenous; Cohort Studies; Conscious Sedation; Diazepam;

2011
The comparison of the effects of dexmedetomidine and midazolam sedation on electroencephalography in pediatric patients with febrile convulsion.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:4

    Topics: Blood Pressure; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Dose-Response Relation

2011
Bispectral index monitoring of midazolam and propofol sedation during endoscopic retrograde cholangiopancreatography: a randomized clinical trial (the EndoBIS study).
    Endoscopy, 2012, Volume: 44, Issue:3

    Topics: Aged; Aged, 80 and over; Anesthesia Recovery Period; Bradycardia; Cholangiopancreatography, Endoscop

2012
Propofol sedation with bispectral index monitoring is useful for endoscopic submucosal dissection: a randomized prospective phase II clinical trial.
    Endoscopy, 2012, Volume: 44, Issue:6

    Topics: Adenoma; Aged; Aged, 80 and over; Anesthetics, Intravenous; Bradycardia; Chi-Square Distribution; Co

2012
Dexmedetomidine versus midazolam for the sedation of patients with non-invasive ventilation failure.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:17

    Topics: Aged; Cohort Studies; Cross Infection; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hyp

2012
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
High-frequency oscillation in early acute respiratory distress syndrome.
    The New England journal of medicine, 2013, Feb-28, Volume: 368, Issue:9

    Topics: Adult; Aged; Female; High-Frequency Ventilation; Hospital Mortality; Humans; Hypnotics and Sedatives

2013
Paramedic-performed rapid sequence intubation of patients with severe head injuries.
    Annals of emergency medicine, 2002, Volume: 40, Issue:2

    Topics: Adult; Allied Health Personnel; Craniocerebral Trauma; Emergency Medical Services; Humans; Hypnotics

2002
Clinical observations during induction and recovery of xylazine-midazolam- propofol anesthesia in horses.
    The Journal of veterinary medical science, 2003, Volume: 65, Issue:7

    Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Blood Pressu

2003
Nocturnal arterial oxygen desaturation and episodic airway obstruction after ambulatory surgery.
    Anesthesia and analgesia, 2004, Volume: 99, Issue:1

    Topics: Adult; Aged; Airway Obstruction; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia; Ane

2004
The utility of supplemental oxygen during emergency department procedural sedation and analgesia with midazolam and fentanyl: a randomized, controlled trial.
    Annals of emergency medicine, 2007, Volume: 49, Issue:1

    Topics: Adolescent; Adult; Aged; Analgesia; Analgesics, Opioid; Capnography; Child; Child, Preschool; Consci

2007
Etomidate versus midazolam for procedural sedation in pediatric outpatients: a randomized controlled trial.
    Annals of emergency medicine, 2006, Volume: 48, Issue:4

    Topics: Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Consumer Behavior

2006
Hypoxemia during outpatient gastrointestinal endoscopy: the effects of sedation and supplemental oxygen.
    Journal of clinical anesthesia, 1995, Volume: 7, Issue:2

    Topics: Electrocardiography; Endoscopy, Gastrointestinal; Female; Humans; Hypoxia; Injections, Intravenous;

1995
Safety and effectiveness of intranasal administration of sedative medications (ketamine, midazolam, or sufentanil) for urgent brief pediatric dental procedures.
    Anesthesia progress, 1993, Volume: 40, Issue:3

    Topics: Administration, Intranasal; Anesthesia Recovery Period; Anesthesia, Dental; Child Behavior; Child, P

1993
The administration of supplementary oxygen to prevent hypoxia during upper alimentary endoscopy.
    Endoscopy, 1993, Volume: 25, Issue:4

    Topics: Costs and Cost Analysis; Diazepam; Endoscopy, Gastrointestinal; Female; Humans; Hypoxia; Male; Midaz

1993
The effect of flumazenil on midazolam-induced depression of the ventilatory response to hypoxia during isohypercarbia.
    Anesthesiology, 1993, Volume: 78, Issue:4

    Topics: Adult; Depression, Chemical; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interaction

1993
Combined use of spinal anesthesia and midazolam sedation increases the risk of hypoxemia.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:1

    Topics: Anesthesia, Spinal; Double-Blind Method; Humans; Hypnotics and Sedatives; Hypoxia; Midazolam; Prospe

1996
Effect of flumazenil on ventilatory drive during sedation with midazolam and alfentanil.
    Anesthesiology, 1996, Volume: 85, Issue:4

    Topics: Adult; Alfentanil; Analgesics, Opioid; Antidotes; Benzodiazepines; Carbon Dioxide; Conscious Sedatio

1996
Use of a modified non-rebreathing mask during upper intestinal endoscopy.
    Endoscopy, 1996, Volume: 28, Issue:8

    Topics: Adult; Aged; Endoscopy, Digestive System; Female; Humans; Hypnotics and Sedatives; Hypoxia; Incidenc

1996
Pulse oximetry at fibre-optic bronchoscopy in local anaesthesia: indication for postbronchoscopy oxygen supplementation?
    Respiratory medicine, 1998, Volume: 92, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Local; Bronchoscopy; Diazepam; Female; Fiber Optic Techn

1998
Cardiovascular responses, arterial oxygen saturation and plasma catecholamine concentration during upper gastrointestinal endoscopy using conscious sedation with midazolam or propofol.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Aged; Blood Pressure; Conscious Sedation; Electrocardiography, Ambulatory; Endoscopy, Gastrointestin

1998
The effects of flumazenil on alertness and hypoxia in elderly patients after ERCP.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:6

    Topics: Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Double-Blind Method; Femal

1992
Does nasal oxygen reduce the cardiorespiratory problems experienced by elderly patients undergoing endoscopic retrograde cholangiopancreatography?
    Gut, 1992, Volume: 33, Issue:7

    Topics: Administration, Intranasal; Aged; Aged, 80 and over; Anesthesia; Cholangiopancreatography, Endoscopi

1992
Changes in oxygen saturation using two different sedation techniques.
    The British journal of oral & maxillofacial surgery, 1991, Volume: 29, Issue:2

    Topics: Conscious Sedation; Drug Combinations; Humans; Hypoxia; Midazolam; Nalbuphine; Oximetry; Oxygen; Oxy

1991
Effect of conscious sedation with midazolam on oxygen saturation.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1988, Volume: 46, Issue:9

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Intravenous; Female; Humans; Hypoxia; Male; Midaz

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988
Sedative doses of midazolam depress hypoxic ventilatory responses in humans.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:4

    Topics: Adult; Glycopyrrolate; Heart Rate; Humans; Hypoxia; Midazolam; Oxygen; Physostigmine; Respiration

1988

Other Studies

64 other studies available for midazolam and Anoxemia

ArticleYear
A comparison of immobilisation quality and cardiorespiratory effects of etorphine-azaperone versus etorphine-midazolam combinations in blesbok.
    Journal of the South African Veterinary Association, 2022, Volume: 93, Issue:1

    Topics: Animals; Azaperone; Etorphine; Female; Hypnotics and Sedatives; Hypoxia; Immobilization; Midazolam

2022
A comparative study of the cardiopulmonary and sedative effects of a single intramuscular dose of ketamine anesthetic combinations in rabbits.
    Research in veterinary science, 2020, Volume: 128

    Topics: Acepromazine; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Arterial Pressure; Cross

2020
Altered hepatic drug-metabolizing activity in rats suffering from hypoxemia with experimentally induced acute lung impairment.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:6

    Topics: Acute Lung Injury; Animals; Cytochrome P-450 CYP3A; Disease Models, Animal; Hypoxia; Male; Microsome

2018
Oxygen through suction port: use of a three way stopcock during fiberoptic bronchoscopy.
    Anaesthesia, critical care & pain medicine, 2019, Volume: 38, Issue:1

    Topics: Alveolitis, Extrinsic Allergic; Analgesics, Opioid; Anesthetics, Local; Bronchoscopy; Equipment Desi

2019
Anesthetic Management in Tracheal Dilatation for Severe Tracheal Stenosis.
    The Tokai journal of experimental and clinical medicine, 2018, Jul-20, Volume: 43, Issue:2

    Topics: Aged; Anesthesia; Dexmedetomidine; Dilatation; Female; Humans; Hypoxia; Intubation, Intratracheal; L

2018
Prevention of hypoxemia during endobronchial ultrasound-guided transbronchial needle aspiration: Usefulness of high-flow nasal cannula.
    Respiratory investigation, 2018, Volume: 56, Issue:5

    Topics: Adult; Aged; Cannula; Conscious Sedation; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Femal

2018
Effectiveness and safety of gastrointestinal endoscopy during a specific sedation training program for non-anesthesiologists.
    Revista espanola de enfermedades digestivas, 2019, Volume: 111, Issue:3

    Topics: Adult; Aged; Conscious Sedation; Endoscopy, Gastrointestinal; Female; Fentanyl; Gastroenterologists;

2019
Computer-Assisted Propofol Sedation for Esophagogastroduodenoscopy Is Effective, Efficient, and Safe.
    Digestive diseases and sciences, 2019, Volume: 64, Issue:12

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Anesthetists; Blood Gas Monitorin

2019
Interactions of benzodiazepines with heroin: Respiratory depression, temperature effects, and behavior.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: Animals; Asphyxia; Behavior, Animal; Body Temperature; Brain; Drug Interactions; Electrodes, Implant

2019
[Role of pulse oximetric monitoring during gastrointestinal endoscopy. Prospective multicenter study of the Gastroenterology Working Group of the Veszprém Regional Committee of the Hungarian Academy of Sciences (VEAB)].
    Orvosi hetilap, 2013, May-26, Volume: 154, Issue:21

    Topics: Adjuvants, Anesthesia; Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Cholangiopancr

2013
Risk of sedation for diagnostic esophagogastroduodenoscopy in obstructive sleep apnea patients.
    World journal of gastroenterology, 2013, Aug-07, Volume: 19, Issue:29

    Topics: Adult; Case-Control Studies; Chi-Square Distribution; Deep Sedation; Endoscopy, Digestive System; Fe

2013
Risk factors with intravenous sedation for patients with disabilities.
    Anesthesia progress, 2013,Winter, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Dental; Anesthes

2013
Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3

    Topics: Colonoscopy; Conscious Sedation; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combinat

2014
Conscious sedation for upper endoscopy in the gastric bypass patient: prevalence of cardiopulmonary adverse events and predictors of sedation requirement.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:9

    Topics: Adult; Anesthetics, Intravenous; Arrhythmias, Cardiac; Body Mass Index; Conscious Sedation; Endoscop

2014
Risk Factors and Outcomes of Reversal Agent Use in Moderate Sedation During Endoscopy and Colonoscopy.
    Journal of clinical gastroenterology, 2016, Volume: 50, Issue:3

    Topics: Age Factors; Anti-Arrhythmia Agents; Antidotes; Atropine; Body Mass Index; Bradycardia; Case-Control

2016
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
The value of Integrated Pulmonary Index (IPI) monitoring during endoscopies in children.
    Journal of clinical monitoring and computing, 2015, Volume: 29, Issue:6

    Topics: Adolescent; Algorithms; Anesthetics, Intravenous; Capnography; Child; Child, Preschool; Conscious Se

2015
US states consider execution by nitrogen gas as lethal injections grind to a halt.
    BMJ (Clinical research ed.), 2015, Mar-23, Volume: 350

    Topics: Capital Punishment; Humans; Hypnotics and Sedatives; Hypoxia; Midazolam; Nitrogen; Pentobarbital; Un

2015
Midazolam inhibits the hypoxia-induced up-regulation of erythropoietin in the central nervous system.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Animals; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Brain; Cells, Cultured; Disease M

2015
Outcomes of Propofol Sedation During Emergency Endoscopy Performed for Upper Gastrointestinal Bleeding.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:3

    Topics: Adult; Age Factors; Aged; Anticoagulants; Cerebrovascular Disorders; Cohort Studies; Comorbidity; Di

2016
Tolerance and safety to colonoscopy with conscious sedation in Malaysian adults.
    The Medical journal of Malaysia, 2007, Volume: 62, Issue:4

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Aged, 80 and over; Colonoscopy; Conscious Sedation;

2007
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:5

    Topics: Age Factors; Aged; Ambulatory Surgical Procedures; Body Mass Index; Conscious Sedation; Dose-Respons

2009
[Rhabdomyolysis in severe acute asthma].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Acidosis; Acute Disease; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Combined Modal

2009
Low plasma potassium in deep hypothermic cardiac arrest indicates that cardiac arrest is secondary to hypothermia: a porcine study.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2010, Volume: 17, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Azaperone; Biomarkers; Body Temperature; Circulatory Arrest, Deep

2010
Safety of transesophageal echocardiography in adults: study in a multidisciplinary hospital.
    Arquivos brasileiros de cardiologia, 2009, Volume: 93, Issue:5

    Topics: Aged; Anesthetics, Intravenous; Brazil; Conscious Sedation; Dose-Response Relationship, Drug; Echoca

2009
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].
    Revista espanola de anestesiologia y reanimacion, 2010, Volume: 57, Issue:2

    Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatogra

2010
Adverse events during monitored anesthesia care for GI endoscopy: an 8-year experience.
    Gastrointestinal endoscopy, 2011, Volume: 74, Issue:2

    Topics: Adolescent; Age Factors; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Body Mass Index; Bradyca

2011
Medetomidine/midazolam/ketamine anaesthesia in ferrets: effects on cardiorespiratory parameters and evaluation of plasma drug concentrations.
    Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:5

    Topics: Anesthesia; Anesthetics, Combined; Animals; Blood Gas Analysis; Blood Pressure; Dose-Response Relati

2011
Analysis of oxygen saturations recorded during dental intravenous sedations: a retrospective quality assurance of 3500 cases.
    Anesthesia progress, 2011,Fall, Volume: 58, Issue:3

    Topics: Adult; Anesthesia, Dental; Anesthesia, Intravenous; Anesthetics, Intravenous; Conscious Sedation; Fe

2011
Safety and comfort during sedation for diagnostic or therapeutic procedures.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2002, Volume: 8, Issue:4

    Topics: Adult; Anesthetics, Intravenous; Conscious Sedation; Humans; Hypnotics and Sedatives; Hypoxia; Midaz

2002
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured;

2003
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
    Annals of emergency medicine, 2003, Volume: 42, Issue:5

    Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C

2003
When is a patient safe for discharge after procedural sedation? The timing of adverse effect events in 1367 pediatric procedural sedations.
    Annals of emergency medicine, 2003, Volume: 42, Issue:5

    Topics: Adjuvants, Anesthesia; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissociative;

2003
[Anesthetic management for a patient with platypnea-orthodeoxia syndrome].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:2

    Topics: Aged; Anesthesia, General; Dyspnea; Fentanyl; Heart Septal Defects, Atrial; Humans; Hypoxia; Male; M

2004
Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations.
    Radiology, 2005, Volume: 237, Issue:1

    Topics: Cardiovascular System; Child, Preschool; Chloral Hydrate; Conscious Sedation; Diagnostic Imaging; Fe

2005
Effects of an alveolar recruitment maneuver on cardiovascular and respiratory parameters during total intravenous anesthesia in ponies.
    American journal of veterinary research, 2006, Volume: 67, Issue:1

    Topics: Anesthesia, Intravenous; Animals; Benzodiazepines; Catheterization, Peripheral; Horse Diseases; Hors

2006
Midazolam depresses carotid body chemoreceptor activity.
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:2

    Topics: Action Potentials; Analysis of Variance; Anesthetics, Intravenous; Animals; Carbon Dioxide; Carotid

2006
Effect of midazolam on in vitro cerebral endothelial ICAM-1 expression induced by astrocyte-conditioned medium.
    European journal of anaesthesiology, 2006, Volume: 23, Issue:9

    Topics: Anesthetics, Intravenous; Animals; Astrocytes; Brain; Culture Media, Conditioned; Endothelial Cells;

2006
Conscious sedation on a general ward: the MET and clinical governance.
    Joint Commission journal on quality and patient safety, 2007, Volume: 33, Issue:2

    Topics: Aged; Anesthetics, Intravenous; Conscious Sedation; Emergency Treatment; Fracture Fixation; Humans;

2007
Low-dose ketamine: efficacy in pediatric sedation.
    Pediatric emergency care, 2007, Volume: 23, Issue:3

    Topics: Adolescent; Atropine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Evaluation; Dr

2007
The combative multitrauma patient: a protocol for prehospital management.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2007, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Anesthetics, Dissociative; Behavior Control; Clinical Protocols; Drug Therapy, Co

2007
Balanced anesthesia and ventilation strategies for an alpaca (Lama pacos) with an increased anesthetic-risk.
    Schweizer Archiv fur Tierheilkunde, 2008, Volume: 150, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Camelids, New World; Female; Fentanyl; Hypnotics and Sedatives; Hy

2008
Haemodynamic response to simulated haemorrhage in the rabbit: interaction of i.v. anaesthesia and hypoxia.
    British journal of anaesthesia, 1995, Volume: 75, Issue:5

    Topics: Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Cardiac Output; Hemodynamics

1995
[Arterial hypoxia is common in colonoscopy. An overlooked risk of heavy intravenous sedation].
    Lakartidningen, 1995, Feb-15, Volume: 92, Issue:7

    Topics: Adult; Aged; Colonoscopy; Conscious Sedation; Female; Humans; Hypoxia; Infusions, Intravenous; Male;

1995
General anaesthesia vs sedation for minor gynaecological procedures--a comparative study.
    Singapore medical journal, 1993, Volume: 34, Issue:5

    Topics: Adolescent; Adult; Anesthesia, General; Conscious Sedation; Female; Fentanyl; Genitalia, Female; Hum

1993
Effects of midazolam and flumazenil on ventilation during sustained hypoxia in humans.
    Respiration physiology, 1993, Volume: 94, Issue:1

    Topics: Adult; Analysis of Variance; Brain Stem; Flumazenil; gamma-Aminobutyric Acid; Humans; Hypoxia; Infus

1993
Does flumazenil antagonize midazolam-induced depression of ventilatory response to hypoxia?
    Anesthesiology, 1994, Volume: 80, Issue:1

    Topics: Depression, Chemical; Flumazenil; Humans; Hypoxia; Midazolam; Respiration, Artificial

1994
Routine oxygen during endoscopy? An editorial review.
    Endoscopy, 1993, Volume: 25, Issue:4

    Topics: Costs and Cost Analysis; Diazepam; Endoscopy, Gastrointestinal; Humans; Hypoxia; Midazolam; Obesity;

1993
Sedation induced hypoxemia in lower gastrointestinal endoscopy.
    Endoscopy, 1993, Volume: 25, Issue:4

    Topics: Colonoscopy; Diazepam; Female; Humans; Hypoxia; Male; Meperidine; Midazolam; Middle Aged; Sigmoidosc

1993
The effect of oral midazolam and diazepam on respiration in normal subjects.
    The European respiratory journal, 1993, Volume: 6, Issue:1

    Topics: Administration, Oral; Analysis of Variance; Diazepam; Humans; Hypercapnia; Hypoxia; Male; Midazolam;

1993
Supplemental oxygen after outpatient oral and maxillofacial surgery.
    Anesthesia progress, 1992, Volume: 39, Issue:1-2

    Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia Recovery Period;

1992
Breathing patterns and levels of consciousness in children during administration of nitrous oxide after oral midazolam premedication.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1997, Volume: 55, Issue:12

    Topics: Adjuvants, Anesthesia; Administration, Oral; Airway Obstruction; Analgesia; Anesthesia, Inhalation;

1997
Intranasal midazolam and familial dysautonomia.
    Pediatric neurology, 2000, Volume: 23, Issue:4

    Topics: Administration, Intranasal; Anti-Anxiety Agents; Dysautonomia, Familial; Humans; Hypoxia; Midazolam

2000
Introduction of a new patient monitoring system during dental procedures: pulse oximetry.
    Oral surgery, oral diagnosis : OSD, 1996, Volume: 7

    Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Anesthetics, Intravenous; Dental Care; Diaz

1996
[Parenteral sedation in oral surgical procedures].
    Oral surgery, oral diagnosis : OSD, 1996, Volume: 7

    Topics: Antidotes; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Hypoxia; Infusions, Pa

1996
Pulse oximetry during minor oral surgery with and without intravenous sedation.
    Oral surgery, oral medicine, and oral pathology, 1992, Volume: 74, Issue:5

    Topics: Adult; Aged; Anesthesia, Dental; Anesthesia, Local; Conscious Sedation; Female; Humans; Hypoxia; Mal

1992
MAO inhibitors and coronary artery surgery: a patient death.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:10

    Topics: Acidosis; Anesthesia, Intravenous; Angina, Unstable; Cause of Death; Coronary Artery Bypass; Fentany

1992
[Is premedication in gastroscopy hazardous?].
    Schweizerische medizinische Wochenschrift, 1992, Jun-20, Volume: 122, Issue:25

    Topics: Age Factors; Aged; Gastroscopy; Humans; Hypoxia; Midazolam; Middle Aged; Oxygen; Oxygen Inhalation T

1992
Oxygen saturation during third molar removal with local anaesthetic alone and in combination with intravenous sedation.
    British dental journal, 1991, Oct-05, Volume: 171, Issue:7

    Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthesia, Intravenous; Anesthesia, Local; Conscio

1991
Effect of i.v. midazolam on the ventilatory response to sustained hypoxia in man.
    British journal of anaesthesia, 1991, Volume: 66, Issue:4

    Topics: Adult; Anesthesia, Intravenous; Humans; Hyperventilation; Hypoxia; Male; Midazolam; Respiration; Res

1991
Fibreoptic bronchoscopy without general anaesthetic.
    Archives of disease in childhood, 1991, Volume: 66, Issue:4

    Topics: Adolescent; Adult; Anesthesia, Local; Bronchoscopes; Bronchoscopy; Child; Child, Preschool; Consciou

1991
Midazolam improves electrophysiologic recovery after anoxia and reduces the changes in ATP levels and calcium influx during anoxia in the rat hippocampal slice.
    Anesthesiology, 1991, Volume: 74, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Evoked Potentials; Hippocampus; Hypoxia; In Vitro Techniqu

1991
Fiberoptic bronchoscopy in ventilated patients. Evaluation of cardiopulmonary risk under midazolam sedation.
    Chest, 1990, Volume: 97, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bronchoscopy; Carbon Dioxide; Female; Hemodynamics; Humans; Hydrogen

1990
Frequent hypoxemia and apnea after sedation with midazolam and fentanyl.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Apnea; Carbon Dioxide; Conscious Sedation; Drug Interactions; Drug Therapy, Combi

1990
Frequent hypoxemia and apnea after sedation with midazolam and fentanyl.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Apnea; Carbon Dioxide; Conscious Sedation; Drug Interactions; Drug Therapy, Combi

1990
Frequent hypoxemia and apnea after sedation with midazolam and fentanyl.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Apnea; Carbon Dioxide; Conscious Sedation; Drug Interactions; Drug Therapy, Combi

1990
Frequent hypoxemia and apnea after sedation with midazolam and fentanyl.
    Anesthesiology, 1990, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Apnea; Carbon Dioxide; Conscious Sedation; Drug Interactions; Drug Therapy, Combi

1990
Prevention of hypoxaemia during upper-gastrointestinal endoscopy by means of oxygen via nasal cannulae.
    Lancet (London, England), 1987, May-02, Volume: 1, Issue:8540

    Topics: Duodenoscopy; Endoscopy; Esophagoscopy; Female; Gastroscopy; Humans; Hypoxia; Injections, Intravenou

1987