Page last updated: 2024-10-31

midazolam and Anhedonia

midazolam has been researched along with Anhedonia in 1 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).

Research Excerpts

ExcerptRelevanceReference
" These findings may help explain the more modest findings in clinical IV ketamine trials for suicidal ideation than overall depression."8.12A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine. ( Ballard, ED; Bloomfield-Clagett, B; Fava, M; Greenstein, DK; Grunebaum, MF; Mathew, SJ; Murrough, JW; Phillips, JL; Sanacora, G; Wilkinson, ST; Zarate, CA, 2022)
" These findings may help explain the more modest findings in clinical IV ketamine trials for suicidal ideation than overall depression."4.12A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine. ( Ballard, ED; Bloomfield-Clagett, B; Fava, M; Greenstein, DK; Grunebaum, MF; Mathew, SJ; Murrough, JW; Phillips, JL; Sanacora, G; Wilkinson, ST; Zarate, CA, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Bloomfield-Clagett, B1
Ballard, ED1
Greenstein, DK1
Wilkinson, ST1
Grunebaum, MF1
Murrough, JW1
Mathew, SJ1
Phillips, JL1
Fava, M1
Sanacora, G1
Zarate, CA1

Other Studies

1 other study available for midazolam and Anhedonia

ArticleYear
A Participant-Level Integrative Data Analysis of Differential Placebo Response for Suicidal Ideation and Nonsuicidal Depressive Symptoms in Clinical Trials of Intravenous Racemic Ketamine.
    The international journal of neuropsychopharmacology, 2022, 10-25, Volume: 25, Issue:10

    Topics: Anhedonia; Data Analysis; Depression; Depressive Disorder, Major; Humans; Ketamine; Midazolam; Place

2022