midazolam has been researched along with Amnesia in 84 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
Excerpt | Relevance | Reference |
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"To observe the effects of sedation with midazolam and propofol on anterograde amnesia in critical patients." | 9.13 | [Effects of combination of midazolam and propofol on anterograde amnesia in critical patients]. ( Dai, TJ; Li, JQ; Li, L; Li, MQ; Liu, J; Lu, F; Mo, X; Xu, JY; Xu, YJ; Zhang, Z, 2008) |
"Propofol and midazolam are commonly used in the ICU to alleviate physical and psychological disturbances in consequence of anxiety." | 9.12 | Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety. ( Chen, FC; Hsiao, PC; Liaw, WJ; Tang, YY; Wang, KY; Yue-Cune Chang, YH, 2006) |
" In contrast, a significant difference was observed at a sedation score of two; midazolam produced amnesia in more subjects than did propofol." | 9.12 | Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation. ( Ichinohe, T; Kaneko, Y; Matsuki, Y, 2007) |
" In this study, normal participants were tested on a visual search task, once after an injection of midazolam, an anesthetic that induces temporary amnesia, and once after an injection of saline." | 9.11 | The effect of midazolam on visual search: Implications for understanding amnesia. ( Park, H; Quinlan, J; Reder, LM; Thornton, E, 2004) |
"Midazolam administered orally produces significant anterograde amnesia when given as early as 10 min before a surgical procedure." | 9.09 | Midazolam: effects on amnesia and anxiety in children. ( Alexander, G; Hofstadter, MB; Kain, ZN; Krivutza, DM; Mayes, LC; Reznick, JS; Wang, SM, 2000) |
"01 mg kg-1 on the amnesia and sedation caused by midazolam 2 mg and 5 mg i." | 9.06 | Effect of flumazenil on midazolam-induced amnesia. ( Clarke, RS; McKay, AC; McKinney, MS, 1990) |
"The purpose of this study was to determine the duration of amnesia associated with the intravenous usage of midazolam and fentanyl." | 9.06 | Duration of amnesia associated with midazolam/fentanyl intravenous sedation. ( Bullard, DE; Miller, RI; Patrissi, GA, 1989) |
" Il Midazolam ha un buon effetto induttore di amnesia anterograda, può prevenire e ridurre l'insorgenza di questo evento negativo." | 8.02 | ED50 for intravenous midazolam-induced amnesia and its duration in surgical patients. ( Gao, C; Wang, Y; Wu, AS; Yan, J; Yue, Y, 2021) |
" This study examined the effect of midazolam-induced amnesia on memory for details and the proposed ERP correlates of recognition." | 7.78 | Midazolam-induced amnesia reduces memory for details and affects the ERP correlates of recollection and familiarity. ( Curran, T; Nyhus, E, 2012) |
"We hypothesized anterograde amnesia could be predicted by the bispectral index (BIS) during epidural puncture in patients premedicated with intramuscular midazolam." | 7.75 | Bispectral index during epidural puncture predicts anterograde amnesia in patients given midazolam premedication. ( Imanaka, N; Kawashima, H; Nakamura, M; Nakasuji, M; Nomura, M; Tanaka, M; Wada, M, 2009) |
" Using the drug midazolam to induce temporary amnesia we tested participants' memories for newly learned facts in a semantic cue condition or an episodic and semantic cue condition." | 7.73 | Episodic representations support early semantic learning: evidence from midazolam induced amnesia. ( Berrigan, M; Hirshman, E; Hsu, J; Merritt, P; Zamani, S, 2006) |
"In order to identify EEG parameters that might be specific for identifying amnesia during midazolam infusion, we examined changes in the EEG power spectrum associated with a period of amnesia, determined by inability to recall a sequence of numbers and objects presented verbally, after intravenous midazolam 0." | 7.68 | The EEG as a monitor of midazolam amnesia: changes in power and topography as a function of amnesic state. ( Alagesan, R; Bedford, RF; Heino, R; Reinsel, R; Veselis, RA, 1991) |
"In order to examine how the distinction between implicit and explicit memory might relate to theories regarding the organization of memory, two types of memory tests were administered in conjunction with the amnesia-inducing benzodiazepine midazolam." | 7.68 | Midazolam-induced amnesia: implications for the implicit/explicit memory distinction. ( Gray, PA; McCarthy, RA; O'Sullivan, G; Park, GR; Polster, MR, 1993) |
"This experiment investigated the effect of intra-amygdala administration of the GABAergic antagonist bicuculline methiodide on benzodiazepine-induced amnesia." | 7.68 | Bicuculline administered into the amygdala blocks benzodiazepine-induced amnesia. ( Coleman, K; Dickinson-Anson, H; McGaugh, JL; Mesches, MH, 1993) |
"A clinical study was performed investigating the ability of intravenous midazolam to cause amnesia for visual, auditory and painful stimuli presented during surgical removal of third molars." | 7.67 | Intensity and duration of amnesia from intravenous midazolam given for sedation. ( Becker, LE; Hupp, JR, 1988) |
" The control group and the test groups were comparable with regard to biological data, duration of operation, applied dosage of local anaesthetics and actual anxiety before operation." | 6.68 | [Analgesia-sedation for maxillo-facial surgery with midazolam-pentazocine and miazolam-ketamine. Clinical double-blind study of anxiety, analgesia, sedation and amnesia]. ( Daubländer, M; Dick, W; Lipp, M; Sebastian, M, 1995) |
"Retrograde amnesia was measured by postoperative recall and recognition of cards shown prior to midazolam/placebo administration, and anterograde amnesia was measured by postoperative recall and recognition of cards shown during the interval between midazolam/placebo administration and induction of general anesthesia." | 6.67 | Midazolam enhances anterograde but not retrograde amnesia in pediatric patients. ( Beaton, C; Berger, BJ; Hartung, J; McClain, J; Twersky, RS, 1993) |
"Midazolam is a good premedicant for general or regional anesthesia." | 6.37 | Use of midazolam hydrochloride in anesthesia. ( Khanderia, U; Pandit, SK, 1987) |
"To observe the effects of sedation with midazolam and propofol on anterograde amnesia in critical patients." | 5.13 | [Effects of combination of midazolam and propofol on anterograde amnesia in critical patients]. ( Dai, TJ; Li, JQ; Li, L; Li, MQ; Liu, J; Lu, F; Mo, X; Xu, JY; Xu, YJ; Zhang, Z, 2008) |
"Propofol and midazolam are commonly used in the ICU to alleviate physical and psychological disturbances in consequence of anxiety." | 5.12 | Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety. ( Chen, FC; Hsiao, PC; Liaw, WJ; Tang, YY; Wang, KY; Yue-Cune Chang, YH, 2006) |
"This prospective, randomized trial was designed to test the hypothesis that continuous infusion of low-dose remifentanil can provide effective analgesia, sedation, amnesia, patient comfort and stable recovery profile without respiratory depression when compared with propofol infusion during colonoscopy." | 5.12 | Can remifentanil be a better choice than propofol for colonoscopy during monitored anesthesia care? ( Akcaboy, EY; Akcaboy, ZN; Albayrak, D; Altinoren, B; Dikmen, B; Gogus, N, 2006) |
" In contrast, a significant difference was observed at a sedation score of two; midazolam produced amnesia in more subjects than did propofol." | 5.12 | Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation. ( Ichinohe, T; Kaneko, Y; Matsuki, Y, 2007) |
"In a double-blind, placebo-controlled experiment that used midazolam, a benzodiazepine that creates temporary amnesia, we compared acquisition and retention of paired associates of different types." | 5.12 | Retrograde facilitation under midazolam: the role of general and specific interference. ( Anderson, JR; Dickison, D; Dulik, M; Ferris, JL; Gyula, F; Jefferson, BF; Oates, JM; Quinlan, JJ; Reder, LM, 2007) |
" In this study, normal participants were tested on a visual search task, once after an injection of midazolam, an anesthetic that induces temporary amnesia, and once after an injection of saline." | 5.11 | The effect of midazolam on visual search: Implications for understanding amnesia. ( Park, H; Quinlan, J; Reder, LM; Thornton, E, 2004) |
"Midazolam administered orally produces significant anterograde amnesia when given as early as 10 min before a surgical procedure." | 5.09 | Midazolam: effects on amnesia and anxiety in children. ( Alexander, G; Hofstadter, MB; Kain, ZN; Krivutza, DM; Mayes, LC; Reznick, JS; Wang, SM, 2000) |
"To compare the safety and efficacy of two doses of oral midazolam, and to assess the drug induced amnesia obtained, when used for conscious sedation of children undergoing minor procedures in the accident and emergency (A&E) setting." | 5.08 | Oral midazolam for conscious sedation of children during minor procedures. ( Davies, FC; Waters, M, 1998) |
" Low-dose intravenous ketamine as the primary anesthetic following premedication with fentanyl and midazolam, and in conjunction with nitrous oxide, appeared to produce less hypoxia, hypercarbia, and apnea than when methohexital was used." | 5.07 | A double-blind comparison of low-dose intravenous ketamine and methohexital in adults. ( Anderson, JA; Blankstein, KC, 1991) |
"01 mg kg-1 on the amnesia and sedation caused by midazolam 2 mg and 5 mg i." | 5.06 | Effect of flumazenil on midazolam-induced amnesia. ( Clarke, RS; McKay, AC; McKinney, MS, 1990) |
"The purpose of this study was to determine the duration of amnesia associated with the intravenous usage of midazolam and fentanyl." | 5.06 | Duration of amnesia associated with midazolam/fentanyl intravenous sedation. ( Bullard, DE; Miller, RI; Patrissi, GA, 1989) |
" Now, an innovative study offers compelling evidence that even implicit memory can be impaired during amnesia, temporarily induced in healthy subjects using a neuropharmacological manipulation (midazolam)." | 4.82 | Drug-induced amnesia impairs implicit relational memory. ( Chun, MM, 2005) |
" Midazolam is a benzodiazepine commonly administered intravenously during surgical procedures because it reacts rapidly, causes anterograde amnesia, and has few side effects." | 4.31 | Effects of Chronic Oral Administration of Midazolam on Memory and Circadian Rhythms in Rats. ( Kalinina, AI; Murphy, HM; Wideman, CH, 2023) |
" Il Midazolam ha un buon effetto induttore di amnesia anterograda, può prevenire e ridurre l'insorgenza di questo evento negativo." | 4.02 | ED50 for intravenous midazolam-induced amnesia and its duration in surgical patients. ( Gao, C; Wang, Y; Wu, AS; Yan, J; Yue, Y, 2021) |
"With the ultimate goal of investigating boundary conditions for post-reactivation amnesia, we set out to replicate studies in which systemic, post-reactivation administration of midazolam, propranolol, or cycloheximide resulted in amnesia for contextual fear memories." | 3.91 | Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats. ( Alfei, JM; Beckers, T; Luyten, L; Schnell, AE; Schroyens, N, 2019) |
" This study examined the effect of midazolam-induced amnesia on memory for details and the proposed ERP correlates of recognition." | 3.78 | Midazolam-induced amnesia reduces memory for details and affects the ERP correlates of recollection and familiarity. ( Curran, T; Nyhus, E, 2012) |
"We hypothesized anterograde amnesia could be predicted by the bispectral index (BIS) during epidural puncture in patients premedicated with intramuscular midazolam." | 3.75 | Bispectral index during epidural puncture predicts anterograde amnesia in patients given midazolam premedication. ( Imanaka, N; Kawashima, H; Nakamura, M; Nakasuji, M; Nomura, M; Tanaka, M; Wada, M, 2009) |
"Previous human studies have demonstrated that midazolam-induced signal changes on scalp EEG recording include widespread augmentation of sigma-oscillations and that the amplitude of such oscillations is correlated to the severity of midazolam-induced amnesia." | 3.75 | In-vivo animation of midazolam-induced electrocorticographic changes in humans. ( Asano, E; Nishida, M; Sood, S, 2009) |
" Using the drug midazolam to induce temporary amnesia we tested participants' memories for newly learned facts in a semantic cue condition or an episodic and semantic cue condition." | 3.73 | Episodic representations support early semantic learning: evidence from midazolam induced amnesia. ( Berrigan, M; Hirshman, E; Hsu, J; Merritt, P; Zamani, S, 2006) |
"Midazolam and propofol often provoke retrograde amnesia after recovery from anesthesia in humans." | 3.73 | Facilitation of serotonergic activity and amnesia in rats caused by intravenous anesthetics. ( Adachi, N; Arai, T; Semba, K, 2005) |
"In order to examine how the distinction between implicit and explicit memory might relate to theories regarding the organization of memory, two types of memory tests were administered in conjunction with the amnesia-inducing benzodiazepine midazolam." | 3.68 | Midazolam-induced amnesia: implications for the implicit/explicit memory distinction. ( Gray, PA; McCarthy, RA; O'Sullivan, G; Park, GR; Polster, MR, 1993) |
"In order to identify EEG parameters that might be specific for identifying amnesia during midazolam infusion, we examined changes in the EEG power spectrum associated with a period of amnesia, determined by inability to recall a sequence of numbers and objects presented verbally, after intravenous midazolam 0." | 3.68 | The EEG as a monitor of midazolam amnesia: changes in power and topography as a function of amnesic state. ( Alagesan, R; Bedford, RF; Heino, R; Reinsel, R; Veselis, RA, 1991) |
"This experiment investigated the effect of intra-amygdala administration of the GABAergic antagonist bicuculline methiodide on benzodiazepine-induced amnesia." | 3.68 | Bicuculline administered into the amygdala blocks benzodiazepine-induced amnesia. ( Coleman, K; Dickinson-Anson, H; McGaugh, JL; Mesches, MH, 1993) |
"A clinical study was performed investigating the ability of intravenous midazolam to cause amnesia for visual, auditory and painful stimuli presented during surgical removal of third molars." | 3.67 | Intensity and duration of amnesia from intravenous midazolam given for sedation. ( Becker, LE; Hupp, JR, 1988) |
"Five cases are reported in which confusional states and total anterograde amnesia occurred after oral intake of recommended doses of midazolam, a new ultra-short acting benzodiazepine." | 3.67 | [Confusional states following administration of the hypnotic midazolam]. ( Schneider-Helmert, D, 1985) |
" After the first dose of MDZ, preloading with DEX (2 µg/kg/h for 10 minutes) was started and maintained with a dosage of 0." | 2.77 | A comparison of dexmedetomidine sedation with and without midazolam for dental implant surgery. ( Fukayama, H; Kohase, H; Wakita, R, 2012) |
"001), with the combination with propofol giving more favorable results." | 2.76 | Sedation, analgesia, and cardiorespiratory function in colonoscopy using midazolam combined with fentanyl or propofol. ( Shen, SR; Tang, WL; Wang, F; Xiao, DH; Xu, CX, 2011) |
"Postoperative pain was treated with 30 mg dihydrocodeine." | 2.69 | Pharmacokinetics and the pharmacodynamic action of midazolam in young and elderly patients undergoing tooth extraction. ( Dilger, K; Klotz, U; Mikus, G; Platten, HP; Schweizer, E, 1998) |
"Thiopental has mild memory effects whereas fentanyl has none." | 2.68 | The comparative amnestic effects of midazolam, propofol, thiopental, and fentanyl at equisedative concentrations. ( Feshchenko, VA; Reinsel, RA; Veselis, RA; Wroński, M, 1997) |
" The control group and the test groups were comparable with regard to biological data, duration of operation, applied dosage of local anaesthetics and actual anxiety before operation." | 2.68 | [Analgesia-sedation for maxillo-facial surgery with midazolam-pentazocine and miazolam-ketamine. Clinical double-blind study of anxiety, analgesia, sedation and amnesia]. ( Daubländer, M; Dick, W; Lipp, M; Sebastian, M, 1995) |
"Retrograde amnesia was measured by postoperative recall and recognition of cards shown prior to midazolam/placebo administration, and anterograde amnesia was measured by postoperative recall and recognition of cards shown during the interval between midazolam/placebo administration and induction of general anesthesia." | 2.67 | Midazolam enhances anterograde but not retrograde amnesia in pediatric patients. ( Beaton, C; Berger, BJ; Hartung, J; McClain, J; Twersky, RS, 1993) |
"Zolpidem is an effective hypnotic with a rapid onset and short duration of action which may be an alternative to midazolam for premedication." | 2.67 | Preoperative sedation before regional anaesthesia: comparison between zolpidem, midazolam and placebo. ( Forster, A; Gamulin, Z; Praplan-Pahud, J; Sauvanet, JP; Tassonyi, E, 1990) |
"Midazolam was superior to temazepam regarding anxiolysis, sedation and amnesia, but temazepam was superior to placebo." | 2.66 | Benzodiazepine premedication in minor day-case surgery: comparison of oral midazolam and temazepam with placebo. ( Hargreaves, J, 1988) |
"Midazolam 0." | 2.65 | Sedation for fibreoptic gastroscopy: a comparative study of midazolam and diazepam. ( Berggren, L; Eriksson, I; Mollenholt, P; Wickbom, G, 1983) |
"Midazolam seems to be a good alternative for induction of balanced anaesthesia." | 2.65 | Midazolam, a new intravenous induction agent for anaesthesia. ( Brock-Utne, JG; Holloway, AM; Pavy, TJ; Sommerville, TE, 1982) |
"Midazolam is a good premedicant for general or regional anesthesia." | 2.37 | Use of midazolam hydrochloride in anesthesia. ( Khanderia, U; Pandit, SK, 1987) |
"Amnesia is also observed when animals are exposed to the similar context B prior to MDZ administration and later tested for fear to context B but recovers when instead testing for fear to the original training context A or an equally similar but novel context C." | 1.56 | Generalization and recovery of post-retrieval amnesia. ( Alfei, JM; Beckers, T; De Bundel, D; Ferrer Monti, RI; Luyten, L; Molina, VA, 2020) |
"As propofol has some amnesic properties, any instructions given to the patient postoperatively should be in writing." | 1.29 | [Recovery after anesthesia with Diprivan]. ( Nguyen, HN, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (29.76) | 18.7374 |
1990's | 26 (30.95) | 18.2507 |
2000's | 19 (22.62) | 29.6817 |
2010's | 8 (9.52) | 24.3611 |
2020's | 6 (7.14) | 2.80 |
Authors | Studies |
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Yan, J | 1 |
Gao, C | 1 |
Wang, Y | 1 |
Wu, AS | 1 |
Yue, Y | 1 |
Puig-Bosch, X | 1 |
Bieletzki, S | 1 |
Zeilhofer, HU | 1 |
Rudolph, U | 1 |
Antkowiak, B | 1 |
Rammes, G | 1 |
Forman, SA | 1 |
Murphy, HM | 1 |
Kalinina, AI | 1 |
Wideman, CH | 1 |
Schroyens, N | 1 |
Alfei, JM | 2 |
Schnell, AE | 1 |
Luyten, L | 2 |
Beckers, T | 2 |
Ferrer Monti, RI | 1 |
Molina, VA | 1 |
De Bundel, D | 1 |
Schippers, F | 1 |
Pesic, M | 1 |
Saunders, R | 1 |
Borkett, K | 1 |
Searle, S | 1 |
Webster, L | 1 |
Stoehr, T | 1 |
Chen, Y | 1 |
Cai, A | 1 |
Dexter, F | 1 |
Pryor, KO | 1 |
Jacobsohn, EM | 1 |
Glick, DB | 1 |
Willingham, MD | 1 |
Escallier, K | 1 |
Winter, A | 1 |
Avidan, MS | 1 |
Kadono, T | 1 |
Kawano, T | 1 |
Yamanaka, D | 1 |
Tateiwa, H | 1 |
Urakawa, M | 1 |
Locatelli, FM | 1 |
Yokoyama, M | 1 |
Xu, JY | 1 |
Li, MQ | 1 |
Zhang, Z | 1 |
Lu, F | 1 |
Li, L | 1 |
Li, JQ | 1 |
Mo, X | 1 |
Xu, YJ | 1 |
Liu, J | 1 |
Dai, TJ | 1 |
Chandrachud, W | 1 |
Beltes, C | 1 |
Nakasuji, M | 1 |
Nakamura, M | 1 |
Imanaka, N | 1 |
Tanaka, M | 1 |
Nomura, M | 1 |
Wada, M | 1 |
Kawashima, H | 1 |
Nishida, M | 1 |
Sood, S | 1 |
Asano, E | 1 |
Robinson, MJ | 1 |
Franklin, KB | 1 |
Wang, F | 1 |
Shen, SR | 1 |
Xiao, DH | 1 |
Xu, CX | 1 |
Tang, WL | 1 |
Nyhus, E | 1 |
Curran, T | 1 |
Rinehart, JB | 1 |
Baker, B | 1 |
Raphael, D | 1 |
Wakita, R | 1 |
Kohase, H | 1 |
Fukayama, H | 1 |
Gomez, ML | 1 |
Roseman, MM | 1 |
Hirshman, E | 3 |
Fisher, J | 2 |
Henthorn, T | 2 |
Arndt, J | 2 |
Passannante, A | 2 |
Park, H | 1 |
Quinlan, J | 1 |
Thornton, E | 1 |
Reder, LM | 2 |
Semba, K | 1 |
Adachi, N | 1 |
Arai, T | 1 |
Chun, MM | 1 |
Merritt, P | 1 |
Zamani, S | 1 |
Hsu, J | 1 |
Berrigan, M | 1 |
Hsiao, PC | 1 |
Tang, YY | 1 |
Liaw, WJ | 1 |
Yue-Cune Chang, YH | 1 |
Chen, FC | 1 |
Wang, KY | 1 |
Akcaboy, ZN | 1 |
Akcaboy, EY | 1 |
Albayrak, D | 1 |
Altinoren, B | 1 |
Dikmen, B | 1 |
Gogus, N | 1 |
Matsuki, Y | 1 |
Ichinohe, T | 1 |
Kaneko, Y | 1 |
Berry, FA | 1 |
Oates, JM | 1 |
Dickison, D | 1 |
Anderson, JR | 1 |
Gyula, F | 1 |
Quinlan, JJ | 1 |
Ferris, JL | 1 |
Dulik, M | 1 |
Jefferson, BF | 1 |
Gomar Sancho, C | 1 |
Dori Martínez de Salinas, AM | 1 |
Nalda Felipe, MA | 1 |
Berggren, L | 1 |
Eriksson, I | 1 |
Mollenholt, P | 1 |
Wickbom, G | 1 |
Magni, VC | 1 |
Frost, RA | 1 |
Leung, JW | 1 |
Cotton, PB | 1 |
Dixon, J | 1 |
Power, SJ | 1 |
Grundy, EM | 1 |
Lumley, J | 1 |
Morgan, M | 1 |
Korttila, K | 1 |
Subhan, Z | 1 |
Hindmarch, I | 1 |
Holloway, AM | 1 |
Brock-Utne, JG | 1 |
Sommerville, TE | 1 |
Pavy, TJ | 1 |
Driessen, JJ | 1 |
Smets, MJ | 1 |
Goey, LS | 1 |
Booij, LH | 1 |
Dundee, JW | 1 |
Wilson, DB | 1 |
Lipp, M | 1 |
Daubländer, M | 1 |
Sebastian, M | 1 |
Dick, W | 1 |
Williams, TJ | 1 |
Nguyen, HN | 1 |
Dickinson-Anson, H | 2 |
Mesches, MH | 1 |
Coleman, K | 1 |
McGaugh, JL | 2 |
Polster, MR | 2 |
Gray, PA | 2 |
O'Sullivan, G | 2 |
McCarthy, RA | 2 |
Park, GR | 2 |
Stillwell, R | 1 |
Mangar, D | 1 |
Mohamed, SA | 1 |
Markowsky, S | 1 |
Twersky, RS | 1 |
Hartung, J | 1 |
Berger, BJ | 1 |
McClain, J | 1 |
Beaton, C | 1 |
Verheecke, G | 2 |
Veselis, RA | 2 |
Reinsel, RA | 1 |
Feshchenko, VA | 1 |
Wroński, M | 1 |
Platten, HP | 1 |
Schweizer, E | 1 |
Dilger, K | 1 |
Mikus, G | 1 |
Klotz, U | 1 |
Davies, FC | 1 |
Waters, M | 1 |
Barros, DM | 1 |
Izquierdo, LA | 1 |
Quevedo, J | 1 |
Rodrigues, C | 1 |
Madruga, M | 1 |
Medina, JH | 1 |
Izquierdo, I | 1 |
Bagary, M | 1 |
Fluck, E | 1 |
File, SE | 1 |
Joyce, E | 1 |
Lockwood, G | 1 |
Grasby, P | 1 |
Kain, ZN | 1 |
Hofstadter, MB | 1 |
Mayes, LC | 1 |
Krivutza, DM | 1 |
Alexander, G | 1 |
Wang, SM | 1 |
Reznick, JS | 1 |
Barr, J | 1 |
Zomorodi, K | 1 |
Bertaccini, EJ | 1 |
Shafer, SL | 1 |
Geller, E | 1 |
Fuse, A | 1 |
Hosokawa, T | 1 |
Kume, T | 1 |
Hayashi, K | 1 |
Toujo, H | 1 |
Tanaka, Y | 1 |
Curran, HV | 1 |
Birch, B | 1 |
Nuotto, EJ | 1 |
Korttila, KT | 1 |
Lichtor, JL | 1 |
Ostman, PL | 1 |
Rupani, G | 1 |
Kolek, V | 1 |
Jezdinský, J | 1 |
Blankstein, KC | 1 |
Anderson, JA | 2 |
Payne, KA | 1 |
Coetzee, AR | 1 |
Mattheyse, FJ | 1 |
Reinsel, R | 1 |
Alagesan, R | 1 |
Heino, R | 1 |
Bedford, RF | 1 |
Hennessy, MJ | 1 |
Kirkby, KC | 1 |
Montgomery, IM | 1 |
Ochs, MW | 1 |
Tucker, MR | 1 |
Owsley, TG | 1 |
Praplan-Pahud, J | 1 |
Forster, A | 2 |
Gamulin, Z | 1 |
Tassonyi, E | 1 |
Sauvanet, JP | 1 |
McKay, AC | 1 |
McKinney, MS | 1 |
Clarke, RS | 1 |
Short, TG | 1 |
Galletly, DC | 1 |
Gilbert, DB | 1 |
Patterson, TA | 1 |
Rose, SP | 1 |
Brouillette, DE | 1 |
Leventhal, R | 1 |
Kumar, S | 1 |
Berman, D | 1 |
Kajani, M | 1 |
Yoo, YK | 1 |
Carra, J | 1 |
Tarter, R | 1 |
Van Thiel, DH | 1 |
O'Boyle, CA | 1 |
Barry, H | 1 |
Fox, E | 1 |
Harris, D | 1 |
McCreary, C | 1 |
Hargreaves, J | 1 |
Miller, RI | 1 |
Bullard, DE | 1 |
Patrissi, GA | 1 |
Häcki, M | 1 |
Ricou, B | 1 |
Brückner, A | 1 |
Chastonay, P | 1 |
Gemperle, M | 1 |
Sage, DJ | 1 |
Close, A | 1 |
Boas, RA | 1 |
Hupp, JR | 1 |
Becker, LE | 1 |
Schneider-Helmert, D | 1 |
Barclay, JK | 1 |
Hunter, KM | 1 |
McMillan, W | 1 |
Pausawasdi, S | 1 |
Padmasuta, K | 1 |
Tangtrakul, S | 1 |
Chaturachinda, K | 1 |
Khanderia, U | 1 |
Pandit, SK | 1 |
Camann, W | 1 |
Cohen, MB | 1 |
Ostheimer, GW | 1 |
Philip, BK | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Monitoring Awareness and Pain Under Anesthesia Using a New EEG Based System[NCT02938325] | 90 participants (Anticipated) | Observational | 2017-01-01 | Recruiting | |||
[NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for midazolam and Amnesia
Article | Year |
---|---|
Drug-induced amnesia impairs implicit relational memory.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Consciousness; Humans; Mental Recall; Midazolam | 2005 |
Use of midazolam hydrochloride in anesthesia.
Topics: Amnesia; Anesthesia; Anxiety; Cardiovascular System; Humans; Midazolam; Premedication; Respiration | 1987 |
40 trials available for midazolam and Amnesia
Article | Year |
---|---|
Randomized Crossover Trial to Compare Abuse Liability of Intravenous Remimazolam Versus Intravenous Midazolam and Placebo in Recreational Central Nervous System Depressant Users.
Topics: Administration, Intravenous; Adolescent; Adult; Amnesia; Benzodiazepines; Central Nervous System Dep | 2020 |
Amnesia of the Operating Room in the B-Unaware and BAG-RECALL Clinical Trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amnesia; Anesthesia, General; Consciousness Monitors; Fe | 2016 |
[Effects of combination of midazolam and propofol on anterograde amnesia in critical patients].
Topics: Adolescent; Adult; Amnesia; Critical Illness; Drug Therapy, Combination; Female; Humans; Hypnotics a | 2008 |
Sedation, analgesia, and cardiorespiratory function in colonoscopy using midazolam combined with fentanyl or propofol.
Topics: Amnesia; Analgesia; Blood Pressure; Colonoscopy; Demography; Drug Therapy, Combination; Female; Fent | 2011 |
A comparison of dexmedetomidine sedation with and without midazolam for dental implant surgery.
Topics: Adult; Aged; Amnesia; Analysis of Variance; Anesthesia, Dental; Anesthesia, Intravenous; Anesthetics | 2012 |
The amnesic effect of oral Midazolam in children.
Topics: Adjuvants, Anesthesia; Amnesia; Child; Child, Preschool; Dental Anxiety; Dental Care for Children; F | 2003 |
Midazolam amnesia and retrieval from semantic memory: Developing methods to test theories of implicit memory.
Topics: Adult; Amnesia; Cognition; Female; Humans; Hypnotics and Sedatives; Male; Memory Disorders; Midazola | 2003 |
The effect of midazolam on visual search: Implications for understanding amnesia.
Topics: Adult; Amnesia; Humans; Mental Recall; Midazolam; Vision, Ocular | 2004 |
Midazolam amnesia and short-term/working memory processes.
Topics: Adult; Amnesia; Double-Blind Method; Humans; Hypnotics and Sedatives; Injections, Intravenous; Memor | 2006 |
Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety.
Topics: Adult; Aged; Amnesia; Anxiety; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; | 2006 |
Can remifentanil be a better choice than propofol for colonoscopy during monitored anesthesia care?
Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Carbon Dioxide; | 2006 |
Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation.
Topics: Adult; Amnesia; Conscious Sedation; Cross-Over Studies; Dental Care; Dental Pulp; Electric Stimulati | 2007 |
Retrograde facilitation under midazolam: the role of general and specific interference.
Topics: Adolescent; Adult; Amnesia; Cues; Double-Blind Method; Female; GABA Modulators; Humans; Male; Midazo | 2007 |
Sedation for fibreoptic gastroscopy: a comparative study of midazolam and diazepam.
Topics: Adolescent; Adult; Aged; Amnesia; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Female; Fiber Opti | 1983 |
A randomized comparison of midazolam and diazepam for sedation in upper gastrointestinal endoscopy.
Topics: Adolescent; Adult; Aged; Amnesia; Anti-Anxiety Agents; Benzodiazepines; Cholangiopancreatography, En | 1983 |
Midazolam, a new intravenous induction agent for anaesthesia.
Topics: Adult; Amnesia; Anesthesia, Intravenous; Anesthetics; Benzodiazepines; Clinical Trials as Topic; Fem | 1982 |
Comparison of diazepam and midazolam as oral premedicants for bronchoscopy under local anesthesia.
Topics: Amnesia; Anesthesia, Local; Benzodiazepines; Bronchoscopy; Diazepam; Double-Blind Method; Female; Hu | 1982 |
[Analgesia-sedation for maxillo-facial surgery with midazolam-pentazocine and miazolam-ketamine. Clinical double-blind study of anxiety, analgesia, sedation and amnesia].
Topics: Adjuvants, Anesthesia; Adult; Ambulatory Surgical Procedures; Amnesia; Analgesia; Anesthesia; Anesth | 1995 |
Comparison of the sedative and amnesic effects of midazolam and propofol.
Topics: Adolescent; Adult; Amnesia; Humans; Hypnotics and Sedatives; Memory; Midazolam; Propofol; Reaction T | 1993 |
Midazolam enhances anterograde but not retrograde amnesia in pediatric patients.
Topics: Amnesia; Amnesia, Retrograde; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Mi | 1993 |
The comparative amnestic effects of midazolam, propofol, thiopental, and fentanyl at equisedative concentrations.
Topics: Adult; Amnesia; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Memory | 1997 |
Pharmacokinetics and the pharmacodynamic action of midazolam in young and elderly patients undergoing tooth extraction.
Topics: Adolescent; Adult; Aged; Aging; Amnesia; Analgesics, Opioid; Area Under Curve; Codeine; Female; Half | 1998 |
Oral midazolam for conscious sedation of children during minor procedures.
Topics: Administration, Oral; Adolescent; Amnesia; Anti-Anxiety Agents; Child; Child, Preschool; Conscious S | 1998 |
Is benzodiazepine-induced amnesia due to deactivation of the left prefrontal cortex?
Topics: Adult; Amnesia; Anti-Anxiety Agents; Cerebrovascular Circulation; Cognition; Humans; Image Processin | 2000 |
Midazolam: effects on amnesia and anxiety in children.
Topics: Amnesia; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Double-Blind Method; Female; Humans; | 2000 |
A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amnesia; Double-Blind Method; Female; Hemodynamics; Huma | 2001 |
Differentiating the sedative, psychomotor and amnesic effects of benzodiazepines: a study with midazolam and the benzodiazepine antagonist, flumazenil.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Cognition; Double-Blind Method; Emotions; Female; Flicker Fusio | 1991 |
Comparative study of midazolam and diazepam in premedication of bronchoscopy.
Topics: Adult; Amnesia; Anxiety; Bronchoscopy; Diazepam; Double-Blind Method; Female; Humans; Male; Midazola | 1991 |
A double-blind comparison of low-dose intravenous ketamine and methohexital in adults.
Topics: Adolescent; Adult; Amnesia; Anesthesia, Dental; Apnea; Carbon Dioxide; Double-Blind Method; Female; | 1991 |
Comparison of the amnesic effects of midazolam and diazepam.
Topics: Amnesia; Cognition; Diazepam; Double-Blind Method; Female; Humans; Learning; Male; Memory; Midazolam | 1991 |
The effectiveness of flumazenil in reversing the sedation and amnesia produced by intravenous midazolam.
Topics: Amnesia; Anesthesia, Dental; Anesthesia, General; Double-Blind Method; Female; Flumazenil; Humans; M | 1990 |
Preoperative sedation before regional anaesthesia: comparison between zolpidem, midazolam and placebo.
Topics: Adult; Amnesia; Anesthesia, Epidural; Anesthesia, Spinal; Attention; Double-Blind Method; Female; Hu | 1990 |
Effect of flumazenil on midazolam-induced amnesia.
Topics: Adult; Amnesia; Dose-Response Relationship, Drug; Flicker Fusion; Flumazenil; Humans; Memory; Midazo | 1990 |
Double-blind comparison of midazolam and temazepam as oral premedicants for outpatient anaesthesia.
Topics: Adult; Ambulatory Surgical Procedures; Amnesia; Anti-Anxiety Agents; Anxiety; Double-Blind Method; F | 1989 |
Midazolam versus diazepam for combined esophogastroduodenoscopy and colonoscopy.
Topics: Adult; Aged; Amnesia; Analgesia; Diazepam; Digestive System; Endoscopy; Female; Humans; Male; Midazo | 1989 |
Benzodiazepine--induced event amnesia following a stressful surgical procedure.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Blood Pressure; Diazepam; Female; Heart Rate; Humans; Male; Mid | 1987 |
Benzodiazepine premedication in minor day-case surgery: comparison of oral midazolam and temazepam with placebo.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Amnesia; Anesthesia Recovery Period; Anti-A | 1988 |
Duration of amnesia associated with midazolam/fentanyl intravenous sedation.
Topics: Adolescent; Adult; Amnesia; Anesthesia, Dental; Anesthesia, Intravenous; Double-Blind Method; Fentan | 1989 |
Clinical evaluation of a specific benzodiazepine antagonist (RO 15-1788). Studies in elderly patients after regional anaesthesia under benzodiazepine sedation.
Topics: Aged; Amnesia; Anesthesia Recovery Period; Anesthesia, Conduction; Benzodiazepines; Drug Evaluation; | 1986 |
Reversal of midazolam sedation with anexate.
Topics: Aged; Amnesia; Anesthesia Recovery Period; Anesthesia, Spinal; Flumazenil; Hemodynamics; Humans; Mal | 1987 |
42 other studies available for midazolam and Amnesia
Article | Year |
---|---|
ED50 for intravenous midazolam-induced amnesia and its duration in surgical patients.
Topics: Amnesia; Anesthesia, Spinal; Humans; Midazolam | 2021 |
Midazolam at Low Nanomolar Concentrations Affects Long-term Potentiation and Synaptic Transmission Predominantly via the α1-γ-Aminobutyric Acid Type A Receptor Subunit in Mice.
Topics: Amnesia; Animals; Female; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Mice; Midazolam; Re | 2022 |
γ-Aminobutyric Acid Type A Receptor Subtypes and Circuit Connections in Midazolam-induced Amnesia, Sedation, and Hypnosis.
Topics: Amnesia; Conscious Sedation; gamma-Aminobutyric Acid; Humans; Hypnosis; Hypnotics and Sedatives; Mid | 2022 |
Effects of Chronic Oral Administration of Midazolam on Memory and Circadian Rhythms in Rats.
Topics: Administration, Oral; Amnesia; Animals; Benzodiazepines; Circadian Rhythm; Female; Humans; Midazolam | 2023 |
Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats.
Topics: Amnesia; Animals; Conditioning, Psychological; Fear; Hypnotics and Sedatives; Mental Recall; Midazol | 2019 |
Generalization and recovery of post-retrieval amnesia.
Topics: Amnesia; Animals; Fear; Generalization, Psychological; Hypnotics and Sedatives; Male; Memory; Memory | 2020 |
Intranasal midazolam administration enhances amnesic effect in rats.
Topics: Administration, Intranasal; Amnesia; Anesthesia; Animals; Anti-Anxiety Agents; Anticonvulsants; Huma | 2016 |
Intravenous conscious sedation.
Topics: Amnesia; Anesthesia, Dental; Anesthetics, Intravenous; Conscious Sedation; Humans; Male; Midazolam; | 2009 |
Bispectral index during epidural puncture predicts anterograde amnesia in patients given midazolam premedication.
Topics: Adult; Amnesia; Anesthesia, Epidural; Awareness; Electroencephalography; Electromyography; Female; G | 2009 |
In-vivo animation of midazolam-induced electrocorticographic changes in humans.
Topics: Action Potentials; Adolescent; Amnesia; Anesthetics, Intravenous; Anticonvulsants; Biological Clocks | 2009 |
Reconsolidation of a morphine place preference: impact of the strength and age of memory on disruption by propranolol and midazolam.
Topics: Amnesia; Animals; Choice Behavior; Conditioning, Psychological; Drug Synergism; Male; Memory; Midazo | 2010 |
Midazolam-induced amnesia reduces memory for details and affects the ERP correlates of recollection and familiarity.
Topics: Adolescent; Adult; Amnesia; Cerebral Cortex; Electroencephalography; Evoked Potentials; Female; Huma | 2012 |
Postoperative global amnesia reversed with flumazenil.
Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desfluran | 2012 |
Facilitation of serotonergic activity and amnesia in rats caused by intravenous anesthetics.
Topics: Amnesia; Anesthetics, Intravenous; Animals; Avoidance Learning; Brain; Male; Microdialysis; Midazola | 2005 |
Episodic representations support early semantic learning: evidence from midazolam induced amnesia.
Topics: Adult; Amnesia; GABA Modulators; Humans; Learning; Mental Recall; Midazolam; Neuropsychological Test | 2006 |
Midazolam as premedication: is the emperor naked or just half-dressed?
Topics: Adaptation, Psychological; Adjuvants, Anesthesia; Amnesia; Child; Humans; Midazolam; Parent-Child Re | 2007 |
[Study of midazolam in anaesthetic premedication (author's transl)].
Topics: Adolescent; Adult; Aged; Amnesia; Anti-Anxiety Agents; Benzodiazepines; Droperidol; Female; Humans; | 1981 |
Sedation for local anaesthesia. Comparison of intravenous midazolam and diazepam.
Topics: Adult; Amnesia; Anesthesia, Local; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Female; Hemodynam | 1984 |
Clinical effectiveness and untoward effects of new agents and techniques used in intravenous sedation.
Topics: Adult; Amnesia; Analgesics; Anesthesia, Dental; Anesthesia, Intravenous; Anti-Anxiety Agents; Benzod | 1984 |
The effects of midazolam in conjunction with alcohol on iconic memory and free-recall.
Topics: Adult; Amnesia; Benzodiazepines; Drug Synergism; Ethanol; Humans; Memory; Mental Recall; Midazolam; | 1983 |
Amnesic action of midazolam.
Topics: Adult; Amnesia; Amnesia, Retrograde; Benzodiazepines; Female; Humans; Injections, Intravenous; Memor | 1980 |
Sedation in fibreoptic bronchoscopy. Doses that produce amnesia should be given.
Topics: Amnesia; Bronchoscopy; Conscious Sedation; Drug Administration Schedule; Fiber Optic Technology; Hum | 1995 |
[Recovery after anesthesia with Diprivan].
Topics: Amnesia; Anesthesia Recovery Period; Anesthesia, Intravenous; Drug Delivery Systems; Etomidate; Huma | 1994 |
Bicuculline administered into the amygdala blocks benzodiazepine-induced amnesia.
Topics: Amnesia; Amygdala; Animals; Avoidance Learning; Behavior, Animal; Benzodiazepines; Bicuculline; Cath | 1993 |
Intraoperative awareness and recall during total hip arthroplasty.
Topics: Adult; Amnesia; Anemia, Sickle Cell; Drug Tolerance; Female; Hip Prosthesis; Humans; Midazolam; Narc | 1993 |
Midazolam-induced amnesia: implications for the implicit/explicit memory distinction.
Topics: Adolescent; Adult; Amnesia; Female; Humans; Injections, Intramuscular; Male; Memory; Memory Disorder | 1993 |
Bicuculline administered into the amygdala after training blocks benzodiazepine-induced amnesia.
Topics: Amnesia; Amygdala; Animals; Anti-Anxiety Agents; Avoidance Learning; Bicuculline; GABA Antagonists; | 1997 |
Potential morphine sparing effect of midazolam.
Topics: Adjuvants, Anesthesia; Amnesia; Analgesics, Opioid; Humans; Midazolam; Morphine | 1997 |
Interaction between midazolam-induced anterograde amnesia and memory enhancement by treatments given hours later in hippocampus, entorrhinal cortex or posterior parietal cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; | 1998 |
Effects of midazolam--lest we forget: amnesia!
Topics: Amnesia; Anti-Anxiety Agents; Humans; Midazolam; Postoperative Nausea and Vomiting | 1999 |
[Amnesic effect of oral midazolam as premedication in children].
Topics: Administration, Oral; Amnesia; Child; Child, Preschool; Female; Humans; Male; Midazolam; Preanesthet | 1992 |
Sedation and recovery of psychomotor function after intravenous administration of various doses of midazolam and diazepam.
Topics: Adult; Amnesia; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Injections, | 1992 |
Midazolam and amnesia in pediatric premedication.
Topics: Administration, Oral; Amnesia; Child; Child, Preschool; Droperidol; Humans; Injections, Intramuscula | 1991 |
The EEG as a monitor of midazolam amnesia: changes in power and topography as a function of amnesic state.
Topics: Adult; Alpha Rhythm; Amnesia; Beta Rhythm; Electroencephalography; Female; Humans; Infusions, Intrav | 1991 |
Midazolam induces amnesia in a simple, one-trial, maze-learning task in young chicks.
Topics: Amnesia; Animals; Behavior, Animal; Chickens; Conditioning, Psychological; Female; Male; Midazolam; | 1989 |
[Amnesic episodes following administration of the hypnotic drug Midazolam, effect or side-effect?].
Topics: Adult; Amnesia; Benzodiazepines; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sed | 1986 |
Intensity and duration of amnesia from intravenous midazolam given for sedation.
Topics: Amnesia; Anesthesia, Dental; Anesthesia, Intravenous; Humans; Midazolam | 1988 |
[Confusional states following administration of the hypnotic midazolam].
Topics: Adolescent; Adult; Amnesia; Benzodiazepines; Cognition Disorders; Confusion; Female; Humans; Hypnoti | 1985 |
Midazolam and diazepam compared as sedatives for outpatient surgery under local analgesia.
Topics: Adolescent; Adult; Amnesia; Anesthesia, Dental; Anesthesia, Local; Benzodiazepines; Diazepam; Female | 1985 |
Amnesic effect of midazolam as premedication in interval laparoscopic sterilization.
Topics: Administration, Oral; Amnesia; Female; Humans; Meperidine; Midazolam; Premedication; Sterilization, | 1988 |
Is midazolam desirable for sedation in parturients.
Topics: Amnesia; Cesarean Section; Female; Humans; Hypnotics and Sedatives; Labor, Obstetric; Midazolam; Pre | 1986 |
Hazards of amnesia after midazolam in ambulatory surgical patients.
Topics: Ambulatory Surgical Procedures; Amnesia; Humans; Midazolam; Premedication | 1987 |