Page last updated: 2024-10-31

midazolam and Amnesia, Pre-Ictal

midazolam has been researched along with Amnesia, Pre-Ictal in 10 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"Midazolam sedation has been shown to diminish recall of one to four cards shown prior to induction of general anesthesia in pediatric patients."6.67Midazolam enhances anterograde but not retrograde amnesia in pediatric patients. ( Beaton, C; Berger, BJ; Hartung, J; McClain, J; Twersky, RS, 1993)
"To evaluate the effect of midazolam on the global perioperative experience, including patient satisfaction, postoperative nausea and vomiting, postoperative pain, and perioperative anxiety and amnesia."5.11Preoperative intravenous midazolam: benefits beyond anxiolysis. ( Bauer, KP; Dom, PM; O'Flaherty, JE; Ramirez, AM, 2004)
"5 years) undergoing midazolam-induced conscious sedation during painful medical procedures to treat hematological or oncological diseases."5.10Memory in pediatric patients undergoing conscious sedation for aversive medical procedures. ( Dahlquist, LM; Eskenazi, A; Pringle, B, 2003)
"Midazolam effects were measured using visual recognition of posters, recall of specific events, bispectral index (BIS) and sedation visual analogue score."2.71Double-blind randomized controlled trial to determine extent of amnesia with midazolam given immediately before general anaesthesia. ( Bulach, R; Myles, PS; Russnak, M, 2005)
"Midazolam sedation has been shown to diminish recall of one to four cards shown prior to induction of general anesthesia in pediatric patients."2.67Midazolam enhances anterograde but not retrograde amnesia in pediatric patients. ( Beaton, C; Berger, BJ; Hartung, J; McClain, J; Twersky, RS, 1993)
"Midazolam is known to cause anterograde amnesia; however, the possibility of retrograde amnesia has also been raised."1.62Immediate retrograde amnesia induced by midazolam: A prospective, non-randomised cohort study. ( Do, SH; Hwang, JW; Koung Yi, I; Lim, D; Na, HS; Nam, SW; Sohn, HM, 2021)
"We present two cases of retrograde amnesia: one after intravenous sedation and one after general anaesthesia."1.48Retrograde amnesia after intravenous sedation and general anaesthesia in a dental hospital. ( Aulakh, G; Beneng, K; Shokouhi, B, 2018)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Sohn, HM1
Na, HS1
Lim, D1
Koung Yi, I1
Nam, SW1
Do, SH1
Hwang, JW1
Aulakh, G1
Shokouhi, B1
Beneng, K1
Pringle, B1
Dahlquist, LM1
Eskenazi, A1
Bauer, KP1
Dom, PM1
Ramirez, AM1
O'Flaherty, JE1
Bulach, R1
Myles, PS1
Russnak, M1
Fragen, RJ1
Funk, DI1
Avram, MJ1
Costello, C1
DeBruine, K1
Dundee, JW1
Wilson, DB1
Twersky, RS1
Hartung, J1
Berger, BJ1
McClain, J1
Beaton, C1
Koht, A1
Moss, JI1
Takano, M1
Takano, Y1
Sato, I1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Premedication by Midazolam on Preoperative Anxiety for Emergency Surgery[NCT02213302]Phase 459 participants (Actual)Interventional2014-07-31Completed
Nebulized Midazolam, Dexmedetomidine, and Their Combination in Sedation of Preschoolers Undergoing Dental Treatment: A Randomized Clinical Trial[NCT03827408]Phase 272 participants (Actual)Interventional2017-11-27Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for midazolam and Amnesia, Pre-Ictal

ArticleYear
Memory in pediatric patients undergoing conscious sedation for aversive medical procedures.
    Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2003, Volume: 22, Issue:3

    Topics: Adolescent; Amnesia, Retrograde; Anesthetics, Intravenous; Child; Conscious Sedation; Diagnostic Tes

2003
Preoperative intravenous midazolam: benefits beyond anxiolysis.
    Journal of clinical anesthesia, 2004, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Amnesia, Retrograde; Anti-Anxiety Agents; Anxiety; Blood Pressure; Chi-Square Dis

2004
Double-blind randomized controlled trial to determine extent of amnesia with midazolam given immediately before general anaesthesia.
    British journal of anaesthesia, 2005, Volume: 94, Issue:3

    Topics: Adult; Amnesia, Retrograde; Anesthesia, General; Conscious Sedation; Dose-Response Relationship, Dru

2005
Midazolam versus hydroxyzine as intramuscular premedicant.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Amnesia, Retrograde; Anxiety; Atropine; Benzodiazepines; Double-Blind Method; Hum

1983
Midazolam enhances anterograde but not retrograde amnesia in pediatric patients.
    Anesthesiology, 1993, Volume: 78, Issue:1

    Topics: Amnesia; Amnesia, Retrograde; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Mi

1993

Other Studies

5 other studies available for midazolam and Amnesia, Pre-Ictal

ArticleYear
Immediate retrograde amnesia induced by midazolam: A prospective, non-randomised cohort study.
    International journal of clinical practice, 2021, Volume: 75, Issue:11

    Topics: Amnesia, Retrograde; Cohort Studies; Female; Humans; Hypnotics and Sedatives; Midazolam; Pregnancy;

2021
Retrograde amnesia after intravenous sedation and general anaesthesia in a dental hospital.
    The British journal of oral & maxillofacial surgery, 2018, Volume: 56, Issue:7

    Topics: Adult; Amnesia, Retrograde; Anesthesia, General; Female; Humans; Hypnotics and Sedatives; Infusions,

2018
Amnesic action of midazolam.
    Anaesthesia, 1980, Volume: 35, Issue:5

    Topics: Adult; Amnesia; Amnesia, Retrograde; Benzodiazepines; Female; Humans; Injections, Intravenous; Memor

1980
Does midazolam cause retrograde amnesia, and can flumazenil reverse that amnesia?
    Anesthesia and analgesia, 1997, Volume: 85, Issue:1

    Topics: Amnesia, Retrograde; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Benzodiazepines; Flu

1997
[The effect of midazolam on the memory during cesarean section and the modulation by flumazenil].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:1

    Topics: Adult; Amnesia, Retrograde; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthesia, Spinal; Ant

1999