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midazolam and Amnesia, Anterograde

midazolam has been researched along with Amnesia, Anterograde in 7 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Amnesia, Anterograde: Loss of the ability to form new memories beyond a certain point in time. This condition may be organic or psychogenic in origin. Organically induced anterograde amnesia may follow CRANIOCEREBRAL TRAUMA; SEIZURES; ANOXIA; and other conditions which adversely affect neural structures associated with memory formation (e.g., the HIPPOCAMPUS; FORNIX (BRAIN); MAMMILLARY BODIES; and ANTERIOR THALAMIC NUCLEI). (From Memory 1997 Jan-Mar;5(1-2):49-71)

Research Excerpts

ExcerptRelevanceReference
"The level of anterograde amnesia tended to be higher in the midazolam group than in the clorazepate dipotassium group (4% versus 0% for anesthesia administration; 14% versus 4% for surgery), but the difference between groups was not significant."2.71Clorazepate dipotassium versus midazolam for premedication in clear corneal cataract surgery. ( Brockmann, C; Franke, GH; Krohner, H; Laube, T; Steuhl, KP, 2003)
"Midazolam is a benzodiazepine which produces a dense anterograde amnesia, while permitting relatively well-preserved short-term memory, semantic retrieval, and other higher cognitive functions."2.71Metamemory without the memory: are people aware of midazolam-induced amnesia? ( Berrigan, M; Hirshman, E; Hsu, J; Merritt, P, 2005)
"Midazolam is a drug that creates temporary anterograde amnesia."1.33Drug-induced amnesia hurts recognition, but only for memories that can be unitized. ( Kaufer, A; Oates, JM; Quinlan, JJ; Reder, LM; Sauer, J; Thornton, ER, 2006)
"Pretreatment with midazolam prevented the facilitatory effects of those treatments."1.31Interaction between midazolam-induced anterograde amnesia and memory enhancement by treatments given immediately after training on an inhibitory avoidance task in rats. ( Barichello, T; de-Paris, F; Kapczinski, F; Quevedo, J; Roesler, R; Vianna, MR, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Morillo, JS1
Ripoll, JS1
Roldán, CS1
Pérez, ME1
Bellido, PV1
Vázquez, JS1
Richart Aznar, MT1
Fernández Bañuls, E1
Lagardera Miñana, A1
Aragón Alvarez, S1
Liang, P1
Manelis, A1
Liu, X1
Aizenstein, HJ1
Gyulai, F1
Quinlan, JJ2
Reder, LM2
Quevedo, J1
de-Paris, F1
Vianna, MR1
Barichello, T1
Roesler, R1
Kapczinski, F1
Laube, T1
Krohner, H1
Franke, GH1
Brockmann, C1
Steuhl, KP1
Merritt, P1
Hirshman, E1
Hsu, J1
Berrigan, M1
Oates, JM1
Thornton, ER1
Kaufer, A1
Sauer, J1

Trials

3 trials available for midazolam and Amnesia, Anterograde

ArticleYear
Using arterial spin labeling perfusion MRI to explore how midazolam produces anterograde amnesia.
    Neuroscience letters, 2012, Aug-01, Volume: 522, Issue:2

    Topics: Adolescent; Adult; Amnesia, Anterograde; Brain Mapping; Cerebral Arteries; Cerebral Cortex; Cross-Ov

2012
Clorazepate dipotassium versus midazolam for premedication in clear corneal cataract surgery.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:10

    Topics: Administration, Oral; Aged; Amnesia, Anterograde; Anesthetics, Intravenous; Anti-Anxiety Agents; Clo

2003
Metamemory without the memory: are people aware of midazolam-induced amnesia?
    Psychopharmacology, 2005, Volume: 177, Issue:3

    Topics: Adult; Amnesia, Anterograde; Awareness; Benzodiazepines; Conscious Sedation; Cues; Humans; Injection

2005

Other Studies

4 other studies available for midazolam and Amnesia, Anterograde

ArticleYear
[The bispectral index as a predictor of anterograde amnesia caused by premedication with intranasal midazolam].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:5

    Topics: Administration, Intranasal; Amnesia, Anterograde; Electroencephalography; Female; Humans; Hypnotics

2008
[Intranasal midazolam for central venous catheterization of an anxious patient without a peripheral venous access].
    Revista espanola de anestesiologia y reanimacion, 2008, Volume: 55, Issue:10

    Topics: Abscess; Administration, Intranasal; Amnesia, Anterograde; Anti-Anxiety Agents; Anxiety; Catheteriza

2008
Interaction between midazolam-induced anterograde amnesia and memory enhancement by treatments given immediately after training on an inhibitory avoidance task in rats.
    Behavioural pharmacology, 2002, Volume: 13, Issue:4

    Topics: Amnesia, Anterograde; Animals; Avoidance Learning; Dexamethasone; Epinephrine; Female; GABA Modulato

2002
Drug-induced amnesia hurts recognition, but only for memories that can be unitized.
    Psychological science, 2006, Volume: 17, Issue:7

    Topics: Amnesia, Anterograde; Face; Humans; Hypnotics and Sedatives; Memory; Midazolam; Reaction Time; Recog

2006