midazolam has been researched along with Alloxan Diabetes in 5 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam is an anesthetic widely used for anxiolysis and sedation; however, to date, a possible role for midazolam in diabetic kidney disease remains unknown." | 5.72 | Midazolam Ameliorates Hyperglycemia-Induced Glomerular Endothelial Dysfunction by Inhibiting Transglutaminase 2 in Diabetes. ( Cho, S; Ha, KS; Hong, SH; Jeon, HY; Kim, EB; Kim, M; Lee, YJ; Sayyed, ND; Seo, JA, 2022) |
| "Midazolam is an anesthetic widely used for anxiolysis and sedation; however, to date, a possible role for midazolam in diabetic kidney disease remains unknown." | 1.72 | Midazolam Ameliorates Hyperglycemia-Induced Glomerular Endothelial Dysfunction by Inhibiting Transglutaminase 2 in Diabetes. ( Cho, S; Ha, KS; Hong, SH; Jeon, HY; Kim, EB; Kim, M; Lee, YJ; Sayyed, ND; Seo, JA, 2022) |
| "Midazolam is an anesthetic agent commonly used for anesthesia and sedation in surgery." | 1.56 | Anti-metastatic effect of midazolam on melanoma B16F10 cells in the lungs of diabetic mice. ( Ha, KS; Han, ET; Hong, SH; Jeon, HY; Kim, M; Kim, YM; Lee, YJ; Park, WS; Seo, JA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bass, JY | 1 |
| Caravella, JA | 1 |
| Chen, L | 1 |
| Creech, KL | 1 |
| Deaton, DN | 1 |
| Madauss, KP | 1 |
| Marr, HB | 1 |
| McFadyen, RB | 1 |
| Miller, AB | 1 |
| Mills, WY | 1 |
| Navas, F | 1 |
| Parks, DJ | 1 |
| Smalley, TL | 1 |
| Spearing, PK | 1 |
| Todd, D | 1 |
| Williams, SP | 1 |
| Wisely, GB | 1 |
| Xu, G | 1 |
| Gaul, MD | 1 |
| Kuo, GH | 1 |
| Du, F | 1 |
| Xu, JZ | 1 |
| Wallace, N | 1 |
| Hinke, S | 1 |
| Kirchner, T | 1 |
| Silva, J | 1 |
| Huebert, ND | 1 |
| Lee, S | 1 |
| Murray, W | 1 |
| Liang, Y | 1 |
| Demarest, K | 1 |
| Seo, JA | 2 |
| Sayyed, ND | 1 |
| Lee, YJ | 2 |
| Jeon, HY | 2 |
| Kim, EB | 1 |
| Hong, SH | 2 |
| Cho, S | 1 |
| Kim, M | 2 |
| Ha, KS | 2 |
| Wang, Z | 2 |
| Li, QQ | 2 |
| Huang, CK | 2 |
| Dong, YY | 2 |
| Lang, LP | 2 |
| Sun, W | 2 |
| Qian, JC | 2 |
| Zhang, XD | 2 |
| Han, ET | 1 |
| Park, WS | 1 |
| Kim, YM | 1 |
5 other studies available for midazolam and Alloxan Diabetes
| Article | Year |
|---|---|
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
Topics: Animals; Binding Sites; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Dogs | 2011 |
Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors.
Topics: Administration, Oral; Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Drug De | 2018 |
Midazolam Ameliorates Hyperglycemia-Induced Glomerular Endothelial Dysfunction by Inhibiting Transglutaminase 2 in Diabetes.
Topics: Animals; Biomarkers; Calcium; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Neph | 2022 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method.
Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P- | 2023 |
Anti-metastatic effect of midazolam on melanoma B16F10 cells in the lungs of diabetic mice.
Topics: Adjuvants, Anesthesia; Animals; Cell Survival; Diabetes Mellitus, Experimental; Dose-Response Relati | 2020 |