Page last updated: 2024-10-31

midazolam and Allergy, Drug

midazolam has been researched along with Allergy, Drug in 16 studies

Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.

Research Excerpts

ExcerptRelevanceReference
"In our opinion midazolam should be avoided in patients with Cornelia de Lange Syndrome, which we enforced after first unpredictable reaction."3.81Unpredictable drug reaction in a child with Cornelia de Lange syndrome. ( Bokun, Z; Milojevic, I; Simic, D; Stevic, M, 2015)
"We experienced a case of life-threatening hypotension and bronchoconstriction associated with edema in a patient undergoing resection of a tumor of the right mandible following intravenous midazolam for induction of general anesthesia."3.81Anaphylactoid-like Reaction to Midazolam During Oral and Maxillofacial Surgery. ( Ayuse, T; Kurata, S, 2015)
"Midazolam is a short-acting benzodiazepine with central nervous system depressing action, commonly used for conscious sedation for various procedures and for its pharmacologic properties."1.62Allergic reactions to midazolam: A case series from an Italian allergy unit. ( Aruanno, A; Buonomo, A; Nucera, E; Parrinello, G; Rizzi, A, 2021)
"Cefazolin was the most common agent identified (n = 8 [32%]) followed by ondansetron (n = 3 [12%])."1.46Evaluation of periprocedural hypersensitivity reactions. ( Iammatteo, M; Jerschow, E; Keskin, T, 2017)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's4 (25.00)18.2507
2000's3 (18.75)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Nucera, E1
Parrinello, G1
Buonomo, A1
Aruanno, A1
Rizzi, A1
Bernardini, R1
Bonadonna, P1
Catania, P1
Passalacqua, G1
Petrişor, C1
Gherman, N1
Sfichi, M1
Mureşan, M1
Hagău, N2
Iammatteo, M1
Keskin, T1
Jerschow, E1
Stevic, M1
Milojevic, I1
Bokun, Z1
Simic, D1
Ayuse, T2
Kurata, S1
Bologa, RO1
Indrei, CL1
Longrois, D1
Dirzu, DS1
Gherman-Ionica, N1
Shrivastava, S1
Valladares Otero, G1
Martínez Navas, A1
Olmedo Granados, L1
Echevarría Moreno, M1
Boynes, SG1
Lemak, AL1
Skradski, DM1
Cuddy, MA1
Uzun, S1
Dal, D1
Tammelleo, AD1
Fujita, Y1
Ishikawa, H1
Yokota, K1
Banner, W1
Yakel, DL1
Whittaker, SE1
Elstad, MR1
Edge, KR1
Braude, BM1
Press, P1
van Hasselt, CH1

Other Studies

16 other studies available for midazolam and Allergy, Drug

ArticleYear
Allergic reactions to midazolam: A case series from an Italian allergy unit.
    Allergologia et immunopathologia, 2021, Volume: 49, Issue:4

    Topics: Anaphylaxis; Drug Hypersensitivity; Humans; Midazolam

2021
Perioperative midazolam hypersensitivity in a seven-year-old boy.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2017, Volume: 28, Issue:4

    Topics: Adjuvants, Anesthesia; Adrenergic beta-2 Receptor Agonists; Child; Drug Hypersensitivity; Glucocorti

2017
Multiple Anesthetic Drug Sensitization in a Hairdresser With Previous Immediate-Type Hypersensitivity to Penicillin: A Case Report.
    A & A case reports, 2017, Sep-01, Volume: 9, Issue:5

    Topics: Adult; Analgesics, Opioid; Anesthesia, General; Drug Hypersensitivity; Female; Humans; Hypersensitiv

2017
Evaluation of periprocedural hypersensitivity reactions.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Aged; Anesthetics, General; Anesthetics, Intravenous; Anti-Bacterial Agents; Cefa

2017
Unpredictable drug reaction in a child with Cornelia de Lange syndrome.
    International journal of clinical pharmacy, 2015, Volume: 37, Issue:1

    Topics: Anti-Anxiety Agents; Child, Preschool; De Lange Syndrome; Drug Hypersensitivity; Female; Humans; Mal

2015
Anaphylactoid-like Reaction to Midazolam During Oral and Maxillofacial Surgery.
    Anesthesia progress, 2015,Summer, Volume: 62, Issue:2

    Topics: Anaphylaxis; Anesthetics, Inhalation; Bronchial Diseases; Constriction, Pathologic; Drug Hypersensit

2015
Maximum non-reactive concentration of midazolam and ketamine for skin testing study in non-allergic healthy volunteers.
    Anaesthesia and intensive care, 2010, Volume: 38, Issue:3

    Topics: Adult; Drug Hypersensitivity; Female; Humans; Intradermal Tests; Ketamine; Male; Midazolam; Skin Tes

2010
An experience with midazolam anaphylactoid reaction.
    Journal of anesthesia, 2012, Volume: 26, Issue:4

    Topics: Adult; Anaphylaxis; Drug Eruptions; Drug Hypersensitivity; Epinephrine; Hemodynamics; Humans; Hypnot

2012
[Emergency axillary brachial plexus block in a patient allergic to atropine].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:3

    Topics: Atropine; Axilla; Brachial Plexus; Bronchial Spasm; Child; Contraindications; Drug Hypersensitivity;

2006
An allergic reaction following intramuscular administration of ketamine and midazolam.
    The Journal of clinical pediatric dentistry, 2006,Winter, Volume: 31, Issue:2

    Topics: Anesthetics, Dissociative; Child; Drug Eruptions; Drug Hypersensitivity; Female; Follow-Up Studies;

2006
Unexpected complications of intranasal midazolam premedication.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:8

    Topics: Adjuvants, Anesthesia; Administration, Intranasal; Child; Child, Preschool; Drug Hypersensitivity; F

2007
Pt. allergic to meds: nurse placing hep-lock joined as defendant.
    The Regan report on nursing law, 1995, Volume: 36, Issue:4

    Topics: Alabama; Catheters, Indwelling; Drug Hypersensitivity; Female; Humans; Malpractice; Midazolam; Nursi

1995
Anaphylactoid reaction to midazolam.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:4

    Topics: Adult; Anaphylaxis; Drug Hypersensitivity; Hemodynamics; Humans; Male; Midazolam; Spinal Fusion

1994
A scorpion by any other name is still a scorpion.
    Annals of emergency medicine, 1999, Volume: 34, Issue:5

    Topics: Animals; Antivenins; Drug Hypersensitivity; Humans; Hypnotics and Sedatives; Midazolam; Scorpion Sti

1999
Midazolam-induced angioedema and bronchoconstriction.
    Critical care medicine, 1992, Volume: 20, Issue:2

    Topics: Adult; Angioedema; Asthma; Bronchoconstriction; Drug Hypersensitivity; Female; Humans; Midazolam

1992
Dissociative anaesthesia for coronary artery bypass surgery using ketamine and midazolam. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Nov-08, Volume: 70, Issue:10

    Topics: Anesthesia, Intravenous; Coronary Artery Bypass; Drug Hypersensitivity; Humans; Intraoperative Care;

1986