midazolam has been researched along with Alagille Syndrome in 2 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Alagille Syndrome: A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alagille syndrome (syndromic paucity of interlobular bile ducts) is the most common form of familial intrahepatic cholestasis." | 1.32 | Combined general and epidural anesthesia for a child with alagille syndrome: a case report. ( Myers, LB; Subramaniam, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Subramaniam, K | 1 |
| Myers, LB | 1 |
| Yildiz, TS | 1 |
| Yumuk, NO | 1 |
| Baykal, D | 1 |
| Solak, M | 1 |
| Toker, K | 1 |
2 other studies available for midazolam and Alagille Syndrome
| Article | Year |
|---|---|
Combined general and epidural anesthesia for a child with alagille syndrome: a case report.
Topics: Alagille Syndrome; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Combined; Anesthetics, In | 2004 |
Alagille syndrome and anesthesia management.
Topics: Alagille Syndrome; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Bo | 2007 |