midazolam has been researched along with Adolescent Obesity in 2 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Midazolam is a first-line drug for the treatment of status epilepticus, both by buccal and intravenous administration." | 2.94 | Midazolam Pharmacokinetics in Obese and Non-obese Children and Adolescents. ( Burhenne, J; Christensen, HR; Dalhoff, K; Gade, C; Holm, JC; Holst, H; Johansen, MØ; Lund, TM; Mikus, G; Sonne, J; Sverrisdóttir, E, 2020) |
| " The impact of obesity-related alterations on drug metabolism and its consequences for drug dosing remains largely unknown in both children and adults." | 2.82 | The CYTONOX trial. ( Christensen, HR; Dalhoff, KP; Gade, C; Holm, JC; Holst, H; Mikus, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gade, C | 2 |
| Sverrisdóttir, E | 1 |
| Dalhoff, K | 1 |
| Sonne, J | 1 |
| Johansen, MØ | 1 |
| Christensen, HR | 2 |
| Burhenne, J | 1 |
| Mikus, G | 2 |
| Holm, JC | 2 |
| Lund, TM | 1 |
| Holst, H | 2 |
| Dalhoff, KP | 1 |
2 trials available for midazolam and Adolescent Obesity
| Article | Year |
|---|---|
Midazolam Pharmacokinetics in Obese and Non-obese Children and Adolescents.
Topics: Adolescent; Body Mass Index; Body Weight; Child; Humans; Midazolam; Models, Biological; Pediatric Ob | 2020 |
The CYTONOX trial.
Topics: Adolescent; Caffeine; Child; Chlorzoxazone; Clinical Protocols; Cytochrome P-450 CYP1A2; Cytochrome | 2016 |