midazolam has been researched along with Acute Post-Traumatic Stress Disorder in 18 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Eighty-two patients with self-reported dental anxiety either completed treatment with dentist-administered cognitive behavioural therapy (D-CBT, n = 36), or received dental treatment while sedated with midazolam combined with the systemized communication technique "The Four Habits Model" (Four Habits/midazolam, n = 41)." | 5.69 | Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety. ( Hauge, MS; Stora, B; Willumsen, T, 2023) |
| "27 individuals diagnosed with PTSD were randomly assigned to receive either ketamine (0." | 3.30 | Long term structural and functional neural changes following a single infusion of Ketamine in PTSD. ( Amen, S; Duek, O; Gordon, C; Harpaz-Rotem, I; Kelmendi, B; Korem, N; Krystal, JH; Levy, I; Li, Y; Milne, M, 2023) |
| "Ketamine infusion was associated with significant and rapid reduction in PTSD symptom severity, compared with midazolam, when assessed 24 hours after infusion (mean difference in Impact of Event Scale-Revised score, 12." | 2.79 | Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial. ( Aan Het Rot, M; Charney, DS; Feder, A; Iosifescu, D; Kirkwood, K; Lapidus, KA; Morgan, JE; Murrough, JW; Parides, MK; Perez, AM; Saxena, S; Wan, LB, 2014) |
| "The incidence of PTSD was 16." | 1.72 | COVID-19 induced PTSD: Stressors for trauma and acute care surgeons. ( Esposito, TJ; James, MK; McKenzie, K; Robitsek, RJ; Valenzuela, JY, 2022) |
| "While post-traumatic stress disorder (PTSD) can develop after exposure to severe traumatic events, data have shown that individuals with high sensation-seeking personality traits are less prone to developing PTSD." | 1.56 | Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats. ( Chacho, NM; Dravid, SM; Pipitone, L; Stairs, DJ; Wunsch, C, 2020) |
| "Background Psychomotor agitation can be problematic in an overcrowded emergency department (ED) during uncontrolled procedural sedation." | 1.51 | Post-traumatic stress disorder or emergence phenomena? A case of psychomotor agitation after procedural sedation and analgesia. ( Akbari, H; Bahreini, M; Jalali, A, 2019) |
| "Post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder that may develop after an individual has experienced or witnessed a severe traumatic event." | 1.40 | Midazolam ameliorates the behavior deficits of a rat posttraumatic stress disorder model through dual 18 kDa translocator protein and central benzodiazepine receptor and neurosteroidogenesis. ( Fang, WW; Guo, WZ; Li, BW; Li, YF; Liu, J; Liu, Y; Miao, YL; Shi, WZ; Wu, W, 2014) |
| "Posttraumatic stress disorder (PTSD) is characterized by the occurrence of a traumatic event that is beyond the normal range of human experience." | 1.40 | Effects of L-theanine on posttraumatic stress disorder induced changes in rat brain gene expression. ( Bentley, M; Ceremuga, GA; Ceremuga, TE; Crawford, D; Edwards, R; Herron, GM; Kemper, JL; Martinson, S; Padron, G; Revels, R; Townsend, WL; Washington, J; Wojcicki, J, 2014) |
| "Posttraumatic stress disorder PTSD is based on memory of a traumatic event." | 1.35 | The relationship of intravenous midazolam and posttraumatic stress disorder development in burned soldiers. ( Black, IH; DeSocio, PA; Garza, TH; Gaylord, KM; Maani, CV; McGhee, LL, 2009) |
| "Current PTSD symptoms were substantially elevated in (S)-ketamine subjects, while there was no difference observed between opioids and racemic ketamines." | 1.33 | Effects of peritraumatic ketamine medication on early and sustained posttraumatic stress symptoms in moderately injured accident victims. ( Badke, A; Domes, G; Hautzinger, M; Reichwald, U; Schönenberg, M, 2005) |
| "Midazolam was judged comparably effective to amobarbital and easier to use." | 1.29 | The use of midazolam with pulse oximetry in the drug-assisted interview. ( Marcum, JM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 5 (27.78) | 2.80 |
| Authors | Studies |
|---|---|
| James, MK | 1 |
| Robitsek, RJ | 1 |
| McKenzie, K | 1 |
| Valenzuela, JY | 1 |
| Esposito, TJ | 1 |
| Duek, O | 1 |
| Korem, N | 1 |
| Li, Y | 1 |
| Kelmendi, B | 1 |
| Amen, S | 1 |
| Gordon, C | 1 |
| Milne, M | 1 |
| Krystal, JH | 1 |
| Levy, I | 1 |
| Harpaz-Rotem, I | 1 |
| Hauge, MS | 1 |
| Willumsen, T | 1 |
| Stora, B | 1 |
| Jalali, A | 1 |
| Akbari, H | 1 |
| Bahreini, M | 1 |
| Stairs, DJ | 1 |
| Chacho, NM | 1 |
| Wunsch, C | 1 |
| Pipitone, L | 1 |
| Dravid, SM | 1 |
| Long, D | 1 |
| Gibbons, K | 1 |
| Le Brocque, R | 1 |
| Schults, JA | 1 |
| Kenardy, J | 1 |
| Dow, B | 1 |
| Nunes, SL | 1 |
| Forsberg, S | 1 |
| Blomqvist, H | 1 |
| Berggren, L | 1 |
| Sörberg, M | 1 |
| Sarapohja, T | 1 |
| Wickerts, CJ | 1 |
| Ceremuga, TE | 2 |
| Shellabarger, P | 1 |
| Persson, T | 1 |
| Fanning, M | 1 |
| Galey, P | 1 |
| Robinson, D | 1 |
| Bertsch, S | 1 |
| Ceremuga, GA | 2 |
| Bentley, M | 2 |
| Feder, A | 1 |
| Parides, MK | 1 |
| Murrough, JW | 1 |
| Perez, AM | 1 |
| Morgan, JE | 1 |
| Saxena, S | 1 |
| Kirkwood, K | 1 |
| Aan Het Rot, M | 1 |
| Lapidus, KA | 1 |
| Wan, LB | 1 |
| Iosifescu, D | 1 |
| Charney, DS | 1 |
| Miao, YL | 1 |
| Guo, WZ | 1 |
| Shi, WZ | 1 |
| Fang, WW | 1 |
| Liu, Y | 1 |
| Liu, J | 1 |
| Li, BW | 1 |
| Wu, W | 1 |
| Li, YF | 1 |
| Martinson, S | 1 |
| Washington, J | 1 |
| Revels, R | 1 |
| Wojcicki, J | 1 |
| Crawford, D | 1 |
| Edwards, R | 1 |
| Kemper, JL | 1 |
| Townsend, WL | 1 |
| Herron, GM | 1 |
| Padron, G | 1 |
| Vet, NJ | 1 |
| de Wildt, SN | 1 |
| Verlaat, CW | 1 |
| Mooij, MG | 1 |
| Tibboel, D | 1 |
| de Hoog, M | 1 |
| Buysse, CM | 1 |
| McGhee, LL | 1 |
| Maani, CV | 1 |
| Garza, TH | 1 |
| DeSocio, PA | 1 |
| Gaylord, KM | 1 |
| Black, IH | 1 |
| Wallace, S | 1 |
| Mecklenburg, B | 1 |
| Hanling, S | 1 |
| Schofield, J | 1 |
| Johnston, AM | 1 |
| de Mello, WF | 1 |
| Strøm, T | 1 |
| Schönenberg, M | 1 |
| Reichwald, U | 1 |
| Domes, G | 1 |
| Badke, A | 1 |
| Hautzinger, M | 1 |
| Marcum, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-interventional Comparison of Sedatives on Weaning From Mechanical Ventilation in Intensive Care Patients[NCT01707680] | 155 participants (Actual) | Observational | 2012-06-01 | Terminated (stopped due to Halted due to slow recruitment) | |||
| Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder[NCT00749203] | Phase 2 | 41 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| Low Dose Ketamine Infusion for Comorbid Posttraumatic Stress Disorder and Chronic Pain Patients[NCT04322968] | Phase 3 | 41 participants (Actual) | Interventional | 2018-01-09 | Completed | ||
| A Single Ketamine Infusion Combined With Music for Suicidal Ideation During a Depressive Episode: A Randomized Open Label Clinical Trial[NCT04658420] | Phase 2 | 200 participants (Anticipated) | Interventional | 2021-07-01 | Not yet recruiting | ||
| Music as a Potential Intervention to Improve Hemodynamic Tolerability of Repetitive Sub-Anesthetic IV Ketamine Infusions in Bipolar and Unipolar Depression: A Pilot Study[NCT04701866] | 32 participants (Actual) | Interventional | 2021-01-11 | Completed | |||
| A Pilot Study to Assess the Efficacy of Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy[NCT05019885] | Phase 2 | 6 participants (Anticipated) | Interventional | 2022-08-26 | Recruiting | ||
| Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department[NCT04260607] | Phase 3 | 2 participants (Actual) | Interventional | 2020-01-14 | Terminated (stopped due to As a busy MTF we were unable to retain a health care provider with the appropriate expertise to buy-in to this study once the initiating PI left military service.) | ||
| Assessing a Combined Ketamine and Online Cognitive Behavioural Therapy Intervention for Treatment Resistant Post-Traumatic Stress Disorder[NCT04771767] | Phase 2 | 16 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | ||
| The Effect of Therapeutic Ketamine Infusions on the Symptoms of Post-Traumatic Stress Disorder in Combat Veterans[NCT03088384] | 30 participants (Actual) | Observational | 2016-11-28 | Completed | |||
| Dexmedetomidine Compared to Midazolam for Symptom Control in Advanced Cancer Patients: A Pilot Randomized Controlled Trial (RCT)[NCT01687751] | Phase 2 | 0 participants (Actual) | Interventional | 2012-11-30 | Withdrawn (stopped due to Study design determined to be not likely feasible) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Clinician-administered structured interview measuring PTSD symptoms. frequency score - scale 0 = none of the time to 4 = most or all of the time intensity score - scale 0 = none to 4 = extreme To meet criteria for a symptom, a patient must meet criteria in both frequency and intensity score for each item. Frequency and intensity and then combined to form a single severity score. 30 questions scale, with total score ranging from 0 to 240. (NCT00749203)
Timeframe: 7 days after first infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 54 |
| Midazolam | 65.69 |
"A 22-item self-report questionnaire measuring PTSD symptoms. Items are rated on a 5-point scale ranging from 0 (not at all) to 4 (extremely). The IES-R yields a total score ranging from 0 (not at all) to 88 (extremely)" (NCT00749203)
Timeframe: 7 days after first infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 25.76 |
| Midazolam | 36.32 |
Clinician-administered questionnaire measuring depressive symptoms. The MADRS-S has 10-items which are based on mood symptoms over the past 7 days. Each items is scored 0 (normal) to 6 (severe depression) with overall score ranges from 0 (normal) to 60 (severe depression). Mean difference between baseline and 2 weeks. (NCT00749203)
Timeframe: 24 hours after first infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 12.6 |
| Midazolam | 10.1 |
Self-report questionnaire measuring depressive symptoms. Each item is rated 0 (no depression) to 3 (severe depression). The total score ranges from 0-27. (NCT00749203)
Timeframe: 24 hours after first infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 12.4 |
| Midazolam | 11.3 |
"Severity of PTSD symptoms; items are rated on a 5-point scale ranging from 0 (not at all) to 4 (extremely). The IES-R yields a total score (ranging from 0 to 88); higher scores mean worse symptoms" (NCT04322968)
Timeframe: 1 week post-infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Chronic Pain With PTSD+IV Ketamine Infusion | 28.22 |
| Chronic Pain With PTSD+IV Ketorolac Infusion | 33.66666667 |
| Chronic Pain Without PTSD+IV Ketamine Infusion | 11.44 |
| Chronic Pain Without PTSD+IV Ketorolac Infusion | 13.41 |
"Severity of PTSD symptoms; items are rated on a 5-point scale ranging from 0 (not at all) to 4 (extremely). The IES-R yields a total score (ranging from 0 to 88); higher scores mean worse symptoms" (NCT04322968)
Timeframe: 24 hrs post-infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Chronic Pain With PTSD+IV Ketamine Infusion | 36.33333333 |
| Chronic Pain With PTSD+IV Ketorolac Infusion | 37 |
| Chronic Pain Without PTSD+IV Ketamine Infusion | 10.44444444 |
| Chronic Pain Without PTSD+IV Ketorolac Infusion | 15.64705882 |
"Severity of chronic pain symptoms; using a ruler, the score is determined by measuring the distance (mm) on the 10-cm line between the no pain anchor and the patient's mark, providing a range of scores from 0-100; a higher score indicates greater pain intensity." (NCT04322968)
Timeframe: 1 week post-infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Chronic Pain With PTSD+IV Ketamine Infusion | 48.22 |
| Chronic Pain With PTSD+IV Ketorolac Infusion | 52.88 |
| Chronic Pain Without PTSD+IV Ketamine Infusion | 43.33 |
| Chronic Pain Without PTSD+IV Ketorolac Infusion | 48.23 |
"Severity of chronic pain symptoms; using a ruler, the score is determined by measuring the distance (mm) on the 10-cm line between the no pain anchor and the patient's mark, providing a range of scores from 0-100; a higher score indicates greater pain intensity." (NCT04322968)
Timeframe: 24 hrs post-infusion
| Intervention | units on a scale (Mean) |
|---|---|
| Chronic Pain With PTSD+IV Ketamine Infusion | 37.22222222 |
| Chronic Pain With PTSD+IV Ketorolac Infusion | 49.66666667 |
| Chronic Pain Without PTSD+IV Ketamine Infusion | 29.88888889 |
| Chronic Pain Without PTSD+IV Ketorolac Infusion | 38.70588235 |
"Severity of pain, impact of pain on daily function, location of pain, pain medications and amount of pain relief in the past 24 hours or the past week; No scoring algorithm, but worst pain or the arithmetic mean of the four severity items can be used as measures of pain severity (a range of 0-10, with 10 being worse scores); the arithmetic mean of the seven interference items can be used as a measure of pain interference (a range of 0-10, with 10 being worse scores). The total score is reported for severity items and interference items, which range from 0-40 and 0-70, respectively. Higher values represent worse outcome." (NCT04322968)
Timeframe: 1 week post-infusion
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain interference Scale | Pain severity Scale | |
| Chronic Pain With PTSD+IV Ketamine Infusion | 38.62 | 20.75 |
| Chronic Pain With PTSD+IV Ketorolac Infusion | 25.66 | 14.66 |
| Chronic Pain Without PTSD+IV Ketamine Infusion | 9.62 | 12.75 |
| Chronic Pain Without PTSD+IV Ketorolac Infusion | 28.33 | 22.66 |
4 trials available for midazolam and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Long term structural and functional neural changes following a single infusion of Ketamine in PTSD.
Topics: Extinction, Psychological; Humans; Ketamine; Midazolam; Pilot Projects; Psychotherapy; Stress Disord | 2023 |
Changes in symptoms of anxiety, depression, and PTSD in an RCT-study of dentist-administered treatment of dental anxiety.
Topics: Anxiety; Dental Anxiety; Dentists; Depression; Humans; Midazolam; Professional Role; Stress Disorder | 2023 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial.
Topics: Administration, Intravenous; Adult; Anti-Anxiety Agents; Chronic Disease; Cross-Over Studies; Depres | 2014 |
Short-Term Health-Related Quality of Life of Critically Ill Children Following Daily Sedation Interruption.
Topics: Adolescent; Child; Child, Preschool; Clinical Protocols; Critical Care; Critical Illness; Deep Sedat | 2016 |
14 other studies available for midazolam and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
COVID-19 induced PTSD: Stressors for trauma and acute care surgeons.
Topics: Adult; COVID-19; Female; Hospitals, University; Humans; Male; Midazolam; Pandemics; Stress Disorders | 2022 |
Post-traumatic stress disorder or emergence phenomena? A case of psychomotor agitation after procedural sedation and analgesia.
Topics: Analgesia; Analgesics; Conscious Sedation; Emergency Service, Hospital; Humans; Injections, Intramus | 2019 |
Environmental enrichment increases cue-dependent freezing and behavioral despair but decreases anxiety-like behavior in rats.
Topics: Animals; Anxiety; Behavior, Animal; Conditioning, Classical; Cues; Fear; Male; Midazolam; Rats; Rats | 2020 |
Midazolam exposure in the paediatric intensive care unit predicts acute post-traumatic stress symptoms in children.
Topics: Australia; Child; Child, Preschool; Humans; Intensive Care Units, Pediatric; Longitudinal Studies; M | 2022 |
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Critical Care; Delirium; Dexmedetomidine; Female; Humans; H | 2018 |
Effects of tetrahydropalmatine on post-traumatic stress disorder-induced changes in rat brain gene expression.
Topics: Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Berberine Alkaloids; | 2013 |
Midazolam ameliorates the behavior deficits of a rat posttraumatic stress disorder model through dual 18 kDa translocator protein and central benzodiazepine receptor and neurosteroidogenesis.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Carrier Proteins; Disease Models, Anim | 2014 |
Effects of L-theanine on posttraumatic stress disorder induced changes in rat brain gene expression.
Topics: Analysis of Variance; Animals; Beverages; Brain; Gene Expression Regulation; Glutamates; Male; Midaz | 2014 |
The relationship of intravenous midazolam and posttraumatic stress disorder development in burned soldiers.
Topics: Anti-Anxiety Agents; Brief Psychiatric Rating Scale; Burns; Case-Control Studies; Humans; Intraopera | 2009 |
Profound reduction in sedation and analgesic requirements using extended dexmedetomidine infusions in a patient with an open abdomen.
Topics: Abdominal Injuries; Analgesics, Non-Narcotic; Dexmedetomidine; Fentanyl; Humans; Infusions, Intraven | 2009 |
Morphine after combat injury and post-traumatic stress disorder.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Fentanyl; Humans; Iraq War, 2003-2011; Ketamine; Mid | 2010 |
Sedation in the ICU.
Topics: Academic Dissertations as Topic; Acute Kidney Injury; Aged; Anxiety; Critical Care; Deep Sedation; D | 2012 |
Effects of peritraumatic ketamine medication on early and sustained posttraumatic stress symptoms in moderately injured accident victims.
Topics: Accidents; Adult; Aged; Female; Humans; Ketamine; Male; Midazolam; Middle Aged; Retrospective Studie | 2005 |
The use of midazolam with pulse oximetry in the drug-assisted interview.
Topics: Adult; Amobarbital; Barbiturates; Conscious Sedation; Depressive Disorder; Female; Humans; Infusions | 1996 |