midazolam has been researched along with Acute Lymphoid Leukemia in 4 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the safety and efficacy of midazolam-ketamine association to control pain induced by diagnostic procedures in paediatric oncology patients." | 7.70 | Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study. ( Granry, JC; Le Moine, P; Monrigal, JP; Pellier, I; Rialland, X; Rod, B, 1999) |
| "During the first 12 hr following the procedures, patients experienced significantly less vomiting/retching and less disruption of activity while receiving ondansetron, and recorded significantly lower pain scores while receiving fentanyl." | 5.13 | Pediatric oncology sedation trial (POST): A double-blind randomized study. ( Barr, RD; Buckley, N; Korz, L; Lappan, J; Nagel, K; Willan, AR, 2008) |
| "We evaluated the safety and efficacy of midazolam-ketamine association to control pain induced by diagnostic procedures in paediatric oncology patients." | 3.70 | Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study. ( Granry, JC; Le Moine, P; Monrigal, JP; Pellier, I; Rialland, X; Rod, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wright, ML | 1 |
| O'Brien, SH | 1 |
| Schloss, B | 1 |
| Stanek, JR | 1 |
| Reed, S | 1 |
| Nagel, K | 1 |
| Willan, AR | 1 |
| Lappan, J | 1 |
| Korz, L | 1 |
| Buckley, N | 1 |
| Barr, RD | 1 |
| Pellier, I | 1 |
| Monrigal, JP | 1 |
| Le Moine, P | 1 |
| Rod, B | 1 |
| Rialland, X | 1 |
| Granry, JC | 1 |
| Friedman, AG | 1 |
| Mulhern, RK | 1 |
| Fairclough, D | 1 |
| Ward, PM | 1 |
| Baker, D | 1 |
| Mirro, J | 1 |
| Rivera, GK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for midazolam and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Pediatric oncology sedation trial (POST): A double-blind randomized study.
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Biopsy, Needle; Bone Marrow Examination; Child; Chil | 2008 |
Midazolam premedication for pediatric bone marrow aspiration and lumbar puncture.
Topics: Adolescent; Anxiety; Biopsy, Needle; Double-Blind Method; Humans; Midazolam; Pain; Pilot Projects; P | 1991 |
2 other studies available for midazolam and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Sedation Practices for Lumbar Punctures in Patients With Acute Lymphoblastic Leukemia: A Multicenter Retrospective Study Using Pediatric Health Information Systems.
Topics: Acute Disease; Adolescent; Anesthesia; Anesthetics, Local; Child; Child, Preschool; Conscious Sedati | 2022 |
Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study.
Topics: Adolescent; Analgesics; Biopsy; Biopsy, Needle; Blood Pressure; Catheterization, Central Venous; Chi | 1999 |