midazolam has been researched along with Acute Disease in 52 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine has been used for several decades in cases of acute pulmonary edema (APE) due to the anxiolytic and vasodilatory properties of the drug." | 9.24 | Study Design and Rationale of "A Multicenter, Open-Labeled, Randomized Controlled Trial Comparing MIdazolam Versus MOrphine in Acute Pulmonary Edema": MIMO Trial. ( Abreu-Gonzalez, P; Aldea-Perona, A; Burillo-Putze, G; Dominguez-Rodriguez, A; Garcia-Saiz, MDM; Harmand, MG; Mirò, O, 2017) |
| " Our aim was to evaluate the efficacy and usability of buccal midazolam in controlling seizures in children with acute prolonged seizures, by comparing it with rectal diazepam." | 9.14 | Efficacy and usability of buccal midazolam in controlling acute prolonged convulsive seizures in children. ( Ashrafi, MR; Bavarian, B; Karimi, P; Khosroshahi, N; Kompani, F; Malamiri, RA; Mirzaei, M; Zarch, AV, 2010) |
| "To compare the efficacy of midazolam and diazepam for treatment of acute seizures in children." | 9.14 | [A control study on the treatment of acute seizures with midazolam and diazepam in children]. ( Tang, RH; Zhou, JB, 2010) |
| "To compare intranasal midazolam, using a Mucosal Atomization Device (IN-MMAD), with rectal diazepam (RD) for the home treatment of seizures in children with epilepsy." | 9.14 | Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy. ( Adelgais, K; Dudley, N; Filloux, F; Firth, S; Greenberg, R; Healy, A; Holsti, M; Olsen, C; Schunk, J, 2010) |
| "Midazolam and sufentanil are common analgesic and sedative drugs, but the effects and mechanisms of the combination of these two drugs on pancreatitis injury have not been fully elucidated." | 7.96 | Effects of midazolam combined with sufentanil on injury and expression of HMGB1 and NF-κB in rats with pancreatitis. ( Liu, Y; Liu, YY; Zhou, H; Zhu, ZH, 2020) |
| "To evaluate if sedation with propofol during catheter-directed thrombolysis (CDT) in patients with acute submassive pulmonary embolism (PE) affects survival." | 7.91 | Sedation with Propofol During Catheter-Directed Thrombolysis for Acute Submassive Pulmonary Embolism Is Associated with Increased Mortality. ( Feranec, N; Guruvadoo, K; Liu, B; Manchec, B; Parente, R; Pepe, J; Tran, T; Vicenti, R; Ward, TJ; Zuchowski, C, 2019) |
| "This case report describes an uncommon complication (blindness) occurring after an inadvertent overdosage of a frequently used local anesthetic (lidocaine) during a regional anesthetic procedure." | 7.71 | Temporary bilateral blindness after acute lidocaine toxicity. ( Sawyer, RJ; von Schroeder, H, 2002) |
| "In all but one child, seizures stopped in 15 s-5 min after injection." | 6.68 | Midazolam in treatment of various types of seizures in children. ( Durmaz, Y; Karabiber, H; Müngen, B; Sahin, S; Yakinci, C, 1997) |
| "When droperidol was compared with placebo, for the outcome of tranquillisation or asleep by 30 minutes we found evidence of a clear difference (1 RCT, N = 227, RR 1." | 6.53 | Droperidol for psychosis-induced aggression or agitation. ( Khokhar, MA; Rathbone, J, 2016) |
| "Morphine has been used for several decades in cases of acute pulmonary edema (APE) due to the anxiolytic and vasodilatory properties of the drug." | 5.24 | Study Design and Rationale of "A Multicenter, Open-Labeled, Randomized Controlled Trial Comparing MIdazolam Versus MOrphine in Acute Pulmonary Edema": MIMO Trial. ( Abreu-Gonzalez, P; Aldea-Perona, A; Burillo-Putze, G; Dominguez-Rodriguez, A; Garcia-Saiz, MDM; Harmand, MG; Mirò, O, 2017) |
| "Acetaminophen alone may not be as effective in reducing pain-related physiological and behavioral changes as acetaminophen plus codeine or ibuprofen plus midazolam during diagnostic tympanocentesis." | 5.15 | Pain management in young children undergoing diagnostic tympanocentesis. ( Chandra, A; Colborn, DK; Hoberman, A; Hooper, EG; Kurs-Lasky, M; Reis, EC; Rockette, HE; Shaikh, N, 2011) |
| " Our aim was to evaluate the efficacy and usability of buccal midazolam in controlling seizures in children with acute prolonged seizures, by comparing it with rectal diazepam." | 5.14 | Efficacy and usability of buccal midazolam in controlling acute prolonged convulsive seizures in children. ( Ashrafi, MR; Bavarian, B; Karimi, P; Khosroshahi, N; Kompani, F; Malamiri, RA; Mirzaei, M; Zarch, AV, 2010) |
| "To compare the efficacy of midazolam and diazepam for treatment of acute seizures in children." | 5.14 | [A control study on the treatment of acute seizures with midazolam and diazepam in children]. ( Tang, RH; Zhou, JB, 2010) |
| "To compare intranasal midazolam, using a Mucosal Atomization Device (IN-MMAD), with rectal diazepam (RD) for the home treatment of seizures in children with epilepsy." | 5.14 | Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy. ( Adelgais, K; Dudley, N; Filloux, F; Firth, S; Greenberg, R; Healy, A; Holsti, M; Olsen, C; Schunk, J, 2010) |
| "Midazolam and sufentanil are common analgesic and sedative drugs, but the effects and mechanisms of the combination of these two drugs on pancreatitis injury have not been fully elucidated." | 3.96 | Effects of midazolam combined with sufentanil on injury and expression of HMGB1 and NF-κB in rats with pancreatitis. ( Liu, Y; Liu, YY; Zhou, H; Zhu, ZH, 2020) |
| "To evaluate if sedation with propofol during catheter-directed thrombolysis (CDT) in patients with acute submassive pulmonary embolism (PE) affects survival." | 3.91 | Sedation with Propofol During Catheter-Directed Thrombolysis for Acute Submassive Pulmonary Embolism Is Associated with Increased Mortality. ( Feranec, N; Guruvadoo, K; Liu, B; Manchec, B; Parente, R; Pepe, J; Tran, T; Vicenti, R; Ward, TJ; Zuchowski, C, 2019) |
| "Rectal diazepam is established as a standard rescue or emergency treatment for seizure or status epilepticus; however, the rectal route of administration has not been universally accepted." | 3.76 | A comparison of midazolam nasal spray and diazepam rectal solution for the residential treatment of seizure exacerbations. ( Bertram, E; de Haan, GJ; Doelman, G; Edelbroek, P; van der Geest, P, 2010) |
| "This case report describes an uncommon complication (blindness) occurring after an inadvertent overdosage of a frequently used local anesthetic (lidocaine) during a regional anesthetic procedure." | 3.71 | Temporary bilateral blindness after acute lidocaine toxicity. ( Sawyer, RJ; von Schroeder, H, 2002) |
| "End of seizure episode (clinically) was defined as cessation of visible epileptic phenomenon or return of purposeful response to external stimuli within 15 min of drug administration." | 2.77 | Intravenous diazepam, midazolam and lorazepam in acute seizure control. ( Gathwala, G; Goel, M; Mittal, K; Singh, J, 2012) |
| "In all but one child, seizures stopped in 15 s-5 min after injection." | 2.68 | Midazolam in treatment of various types of seizures in children. ( Durmaz, Y; Karabiber, H; Müngen, B; Sahin, S; Yakinci, C, 1997) |
| "Bethanechol alone was better than a placebo (P less than 0." | 2.66 | The use of anxiolytic and parasympathomimetic agents in the treatment of postoperative urinary retention following anorectal surgery. A prospective, randomized, double-blind study. ( Gottesman, L; Mazier, WP; Milsom, JW, 1989) |
| "When droperidol was compared with placebo, for the outcome of tranquillisation or asleep by 30 minutes we found evidence of a clear difference (1 RCT, N = 227, RR 1." | 2.53 | Droperidol for psychosis-induced aggression or agitation. ( Khokhar, MA; Rathbone, J, 2016) |
| "Most seizure emergencies occur outside of the hospital, and there is a need for treatment interventions that can be administered quickly and safely by nonclinical caregivers." | 2.52 | Intranasal therapies for acute seizures. ( Kälviäinen, R, 2015) |
| " altered renal and hepatic function, catecholamine-related circulatory changes, altered drug volume of distribution, enteral versus parenteral feeding and morbid obesity, along with concomitant multiple drug regimens may account for the wide inter-individual variability in drug exposure and response in critically ill patients and for the high risk for drug-drug interactions to occur." | 2.45 | Mini-series: II. clinical aspects. clinically relevant CYP450-mediated drug interactions in the ICU. ( de Hoon, J; Meersseman, W; Spriet, I; von Winckelmann, S; Willems, L; Wilmer, A, 2009) |
| "To determine the prognostic factors for encephalopathy with bright tree appearance (BTA) in the acute phase through retrospective case evaluation." | 1.42 | Prognostic factors for acute encephalopathy with bright tree appearance. ( Azuma, J; Iwatani, Y; Kagitani-Shimono, K; Kitai, Y; Nabatame, S; Nagai, T; Nakano, S; Okinaga, T; Ozono, K; Tominaga, K; Yamamoto, T, 2015) |
| "Patients with aneurysmal subarachnoid hemorrhage (aSAH) are common in intensive care units (ICU)." | 1.42 | The effect of tracheotomy on drug consumption in patients with acute aneurysmal subarachnoid hemorrhage: an observational study. ( Kongsgaard, U; Narum, J; Rosseland, LA; Sorteberg, A; Sorteberg, W; Stubhaug, A, 2015) |
| "Unlike LRT, renal failure derived from long ischemia time was observed in CRT recipients, and it is speculated that renal failure affects the PK of CyA." | 1.35 | Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure. ( Fujimoto, K; Fukushima, K; Ito, Y; Kokuhu, T; Okamoto, M; Sugioka, N; Takada, K; Tanaka, Y; Yoshimura, N, 2009) |
| " Reduction of the barbiturate dosage resulted in clinical and subclinical partial seizures appearing repetitively in clusters." | 1.34 | Acute encephalitis with refractory, repetitive partial seizures: case reports of this unusual post-encephalitic epilepsy. ( Inoue, T; Maegaki, Y; Nanba, Y; Ogura, K; Ohno, K; Okamoto, R; Saito, Y; Takahashi, Y; Togawa, M, 2007) |
| " Dosing of the analgesics and sedatives was based on a neonatal sedation score for ventilated infants." | 1.32 | Endogenous distress in ventilated full-term newborns with acute respiratory failure. ( Aretz, S; Licht, C; Roth, B, 2004) |
| "The midazolam was dripped slowly into the anterior nares." | 1.29 | Nasal rather than rectal benzodiazepines in the management of acute childhood seizures? ( Brown, JK; Clarke, M; O'Regan, ME, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (9.62) | 18.7374 |
| 1990's | 8 (15.38) | 18.2507 |
| 2000's | 15 (28.85) | 29.6817 |
| 2010's | 21 (40.38) | 24.3611 |
| 2020's | 3 (5.77) | 2.80 |
| Authors | Studies |
|---|---|
| Wright, ML | 1 |
| O'Brien, SH | 1 |
| Schloss, B | 1 |
| Stanek, JR | 1 |
| Reed, S | 1 |
| Neto Gonçalves, T | 1 |
| Margarida Andrade, M | 1 |
| Manchec, B | 1 |
| Liu, B | 1 |
| Tran, T | 1 |
| Zuchowski, C | 1 |
| Guruvadoo, K | 1 |
| Parente, R | 1 |
| Vicenti, R | 1 |
| Pepe, J | 1 |
| Feranec, N | 1 |
| Ward, TJ | 1 |
| Zhou, H | 1 |
| Zhu, ZH | 1 |
| Liu, Y | 1 |
| Liu, YY | 1 |
| Lee, D | 1 |
| Gladwell, D | 1 |
| Batty, AJ | 1 |
| Brereton, N | 1 |
| Tate, E | 1 |
| Devlin, JW | 1 |
| Al-Qadheeb, NS | 1 |
| Chi, A | 1 |
| Roberts, RJ | 1 |
| Qawi, I | 1 |
| Garpestad, E | 1 |
| Hill, NS | 1 |
| Azuma, J | 1 |
| Nabatame, S | 1 |
| Nakano, S | 1 |
| Iwatani, Y | 1 |
| Kitai, Y | 1 |
| Tominaga, K | 1 |
| Kagitani-Shimono, K | 1 |
| Okinaga, T | 1 |
| Yamamoto, T | 1 |
| Nagai, T | 1 |
| Ozono, K | 1 |
| Rosseland, LA | 1 |
| Narum, J | 1 |
| Stubhaug, A | 1 |
| Kongsgaard, U | 1 |
| Sorteberg, W | 1 |
| Sorteberg, A | 1 |
| Kälviäinen, R | 1 |
| Quesada, L | 1 |
| Gomila, I | 1 |
| Yates, C | 1 |
| Barcelo, C | 1 |
| Puiguriguer, J | 1 |
| Barcelo, B | 1 |
| Taylor, DM | 3 |
| Yap, CYL | 2 |
| Knott, JC | 3 |
| Taylor, SE | 2 |
| Phillips, GA | 3 |
| Karro, J | 2 |
| Chan, EW | 3 |
| Kong, DCM | 2 |
| Castle, DJ | 3 |
| Khokhar, MA | 1 |
| Rathbone, J | 1 |
| Dominguez-Rodriguez, A | 1 |
| Burillo-Putze, G | 1 |
| Garcia-Saiz, MDM | 1 |
| Aldea-Perona, A | 1 |
| Harmand, MG | 1 |
| Mirò, O | 1 |
| Abreu-Gonzalez, P | 1 |
| Spriet, I | 1 |
| Meersseman, W | 1 |
| de Hoon, J | 1 |
| von Winckelmann, S | 1 |
| Wilmer, A | 1 |
| Willems, L | 1 |
| Awab, A | 1 |
| Alilou, M | 1 |
| El Moussaoui, R | 1 |
| El Hijri, A | 1 |
| Azzouzi, A | 1 |
| Sugioka, N | 1 |
| Fujimoto, K | 1 |
| Tanaka, Y | 1 |
| Fukushima, K | 1 |
| Ito, Y | 1 |
| Kokuhu, T | 1 |
| Okamoto, M | 1 |
| Yoshimura, N | 1 |
| Takada, K | 1 |
| de Haan, GJ | 1 |
| van der Geest, P | 1 |
| Doelman, G | 1 |
| Bertram, E | 1 |
| Edelbroek, P | 1 |
| Ashrafi, MR | 1 |
| Khosroshahi, N | 1 |
| Karimi, P | 1 |
| Malamiri, RA | 1 |
| Bavarian, B | 1 |
| Zarch, AV | 1 |
| Mirzaei, M | 1 |
| Kompani, F | 1 |
| Tang, RH | 1 |
| Zhou, JB | 1 |
| Holsti, M | 1 |
| Dudley, N | 1 |
| Schunk, J | 1 |
| Adelgais, K | 1 |
| Greenberg, R | 1 |
| Olsen, C | 1 |
| Healy, A | 1 |
| Firth, S | 1 |
| Filloux, F | 1 |
| Isbister, GK | 1 |
| Calver, LA | 1 |
| Page, CB | 1 |
| Stokes, B | 1 |
| Bryant, JL | 1 |
| Downes, MA | 1 |
| Shaikh, N | 1 |
| Hoberman, A | 1 |
| Kurs-Lasky, M | 1 |
| Rockette, HE | 1 |
| Chandra, A | 1 |
| Colborn, DK | 1 |
| Hooper, EG | 1 |
| Reis, EC | 1 |
| Sirsi, D | 1 |
| Lagae, L | 1 |
| Gathwala, G | 1 |
| Goel, M | 1 |
| Singh, J | 1 |
| Mittal, K | 1 |
| Kong, DC | 1 |
| Caldicott, DG | 1 |
| Edwards, NA | 1 |
| Kruys, A | 1 |
| Kirkbride, KP | 1 |
| Sims, DN | 1 |
| Byard, RW | 1 |
| Prior, M | 1 |
| Irvine, RJ | 1 |
| Aretz, S | 1 |
| Licht, C | 1 |
| Roth, B | 1 |
| Scott, RC | 1 |
| Bhattacharyya, M | 1 |
| Kalra, V | 1 |
| Gulati, S | 1 |
| Saito, Y | 1 |
| Maegaki, Y | 1 |
| Okamoto, R | 1 |
| Ogura, K | 1 |
| Togawa, M | 1 |
| Nanba, Y | 1 |
| Inoue, T | 1 |
| Takahashi, Y | 1 |
| Ohno, K | 1 |
| Bamgbade, OA | 2 |
| Descamps, MJ | 1 |
| Gwilym, S | 1 |
| Weldon, D | 1 |
| Holloway, V | 1 |
| Alfa, JA | 1 |
| Bruder, N | 1 |
| Lassegue, D | 1 |
| Pelissier, D | 1 |
| Graziani, N | 1 |
| François, G | 1 |
| Graff, KJ | 1 |
| Kennedy, RM | 1 |
| Jaffe, DM | 1 |
| O'Regan, ME | 1 |
| Brown, JK | 1 |
| Clarke, M | 1 |
| Yakinci, C | 1 |
| Müngen, B | 1 |
| Sahin, S | 1 |
| Karabiber, H | 1 |
| Durmaz, Y | 1 |
| Oneschuk, D | 1 |
| Lahat, E | 1 |
| Goldman, M | 1 |
| Barr, J | 1 |
| Bistritzer, T | 1 |
| Berkovitch, M | 1 |
| Jeannet, PY | 1 |
| Roulet, E | 1 |
| Maeder-Ingvar, M | 1 |
| Gehri, M | 1 |
| Jutzi, A | 1 |
| Deonna, T | 1 |
| Kamijo, Y | 1 |
| Masuda, T | 1 |
| Nishikawa, T | 1 |
| Tsuruta, H | 1 |
| Ohwada, T | 1 |
| Geffen, J | 1 |
| Sawyer, RJ | 1 |
| von Schroeder, H | 1 |
| Stolarek, IH | 1 |
| Ford, MJ | 1 |
| Conway, EE | 1 |
| Singer, LP | 1 |
| Gottesman, L | 1 |
| Milsom, JW | 1 |
| Mazier, WP | 1 |
| Sury, MR | 1 |
| Billingham, I | 1 |
| Russell, GN | 1 |
| Hopkins, CS | 1 |
| Thornington, R | 1 |
| Vivori, E | 1 |
| Graham, MA | 1 |
| Adams, J | 2 |
| Mendoza, R | 1 |
| Djenderedjian, AH | 1 |
| Ananth, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oro-dispersible Olanzapine (Wafer) Versus Conventional Oral Haloperidol or Diazepam Tablets for the Management of Acute Agitation in the Accident and Emergency Department - a Multicentre Randomised Clinical Trial[NCT03246620] | Phase 4 | 12 participants (Actual) | Interventional | 2017-09-01 | Terminated (stopped due to The study was terminated prematurely due to difficulties in patient recruitment and associated potential for selection bias.) | ||
| Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency in Intensive Care Unit- A Randomized Controlled Trial.[NCT02868827] | Phase 2/Phase 3 | 127 participants (Actual) | Interventional | 2017-08-27 | Terminated (stopped due to The initial plan was 2 years but due to slow recruitment. We were able to screen 635 patients in 4 years and recruited only 127 patients.) | ||
| Intranasal Midazolam Versus Rectal Diazepam for the Home Treatment of Seizure Activity in Pediatric Patients With Epilepsy[NCT00326612] | Phase 2 | 358 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| Ketamine Versus Midazolam for Prehospital Agitation[NCT03554915] | 314 participants (Actual) | Observational | 2017-08-01 | Completed | |||
| Intramuscular Olanzapine Versus Haloperidol or Midazolam for the Management of Acute Agitation in the Emergency Department - a Multicentre Randomised Clinical Trial[NCT02380118] | Phase 4 | 167 participants (Actual) | Interventional | 2014-12-31 | Terminated (stopped due to Primary endpoint reached based on data projection from interim analysis.) | ||
| Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Second Trimester Dilatation and Evacuation[NCT05579288] | Early Phase 1 | 60 participants (Anticipated) | Interventional | 2022-12-31 | Not yet recruiting | ||
| Early Lactate-Directed Therapy on the ICU: A Randomized Controlled Trial[NCT00270673] | Phase 3 | 350 participants (Anticipated) | Interventional | 2006-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Length of seizure. (NCT00326612)
Timeframe: 24 hours
| Intervention | Minutes (Median) |
|---|---|
| Intranasal Midazolam | 3.0 |
| Rectal Diazepam | 4.3 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 21 |
| Rectal Diazepam | 17 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 4 |
| Rectal Diazepam | 3 |
(NCT00326612)
Timeframe: 12 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 1 |
| Rectal Diazepam | 1 |
(NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 5 |
| Rectal Diazepam | 5 |
Respiratory depression was defined as intubation at Emergency Department discharge. (NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 1 |
| Rectal Diazepam | 0 |
Respiratory depression was defined as requiring oxygen at discharge from the Emergency Department. (NCT00326612)
Timeframe: 24 hours
| Intervention | participants (Number) |
|---|---|
| Intranasal Midazolam | 3 |
| Rectal Diazepam | 1 |
5 reviews available for midazolam and Acute Disease
| Article | Year |
|---|---|
Intranasal therapies for acute seizures.
Topics: Acute Disease; Administration, Intranasal; Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; | 2015 |
Droperidol for psychosis-induced aggression or agitation.
Topics: Acute Disease; Aggression; Antipsychotic Agents; Benzodiazepines; Droperidol; Haloperidol; Humans; M | 2016 |
Mini-series: II. clinical aspects. clinically relevant CYP450-mediated drug interactions in the ICU.
Topics: Acute Disease; Analgesics, Opioid; Anti-Bacterial Agents; Anticonvulsants; Benzodiazepines; Catechol | 2009 |
Clinical practice: the treatment of acute convulsive seizures in children.
Topics: Acute Disease; Anticonvulsants; Benzodiazepines; Child; Diazepam; GABA Modulators; Humans; Lorazepam | 2011 |
Severe needle phobia in the perianesthesia setting.
Topics: Acute Disease; Adult; Ambulatory Surgical Procedures; Desensitization, Psychologic; Epilepsies, Part | 2007 |
19 trials available for midazolam and Acute Disease
| Article | Year |
|---|---|
Morphine use in acute cardiogenic pulmonary oedema: is MIMO trial enough to change practice? Letter regarding the article 'Midazolam versus morphine in acute cardiogenic pulmonary oedema: results of a multicentre, open-label, randomized controlled trial'.
Topics: Acute Disease; Heart Failure; Humans; Midazolam; Morphine; Pulmonary Edema | 2022 |
Efficacy and safety of early dexmedetomidine during noninvasive ventilation for patients with acute respiratory failure: a randomized, double-blind, placebo-controlled pilot study.
Topics: Acute Disease; Administration, Intravenous; Aged; Aged, 80 and over; Dexmedetomidine; Dose-Response | 2014 |
Midazolam-Droperidol, Droperidol, or Olanzapine for Acute Agitation: A Randomized Clinical Trial.
Topics: Acute Disease; Adult; Benzodiazepines; Conscious Sedation; Double-Blind Method; Droperidol; Drug The | 2017 |
Intravenous midazolam-droperidol combination, droperidol or olanzapine monotherapy for methamphetamine-related acute agitation: subgroup analysis of a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Akathisia, Drug-Induced; Australia; Benzodiazepines; Dopamin | 2017 |
Study Design and Rationale of "A Multicenter, Open-Labeled, Randomized Controlled Trial Comparing MIdazolam Versus MOrphine in Acute Pulmonary Edema": MIMO Trial.
Topics: Acute Disease; Administration, Intravenous; Anti-Anxiety Agents; Cardiopulmonary Resuscitation; Clin | 2017 |
Efficacy and usability of buccal midazolam in controlling acute prolonged convulsive seizures in children.
Topics: Acute Disease; Administration, Buccal; Administration, Rectal; Anticonvulsants; Child; Child, Presch | 2010 |
[A control study on the treatment of acute seizures with midazolam and diazepam in children].
Topics: Acute Disease; Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Male; Midazolam; | 2010 |
Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy.
Topics: Acute Disease; Administration, Intranasal; Administration, Rectal; Anticonvulsants; Child; Child, Pr | 2010 |
Randomized controlled trial of intramuscular droperidol versus midazolam for violence and acute behavioral disturbance: the DORM study.
Topics: Acute Disease; Adult; Aggression; Double-Blind Method; Droperidol; Drug Therapy, Combination; Emerge | 2010 |
Pain management in young children undergoing diagnostic tympanocentesis.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Biopsy, Fine-Needle; Chi | 2011 |
Is intranasal midazolam better than rectal diazepam for home management of acute seizures?
Topics: Acute Disease; Administration, Intranasal; Administration, Rectal; Child; Diazepam; Disease Manageme | 2011 |
Intravenous diazepam, midazolam and lorazepam in acute seizure control.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Injections, In | 2012 |
Intravenous droperidol or olanzapine as an adjunct to midazolam for the acutely agitated patient: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Benzodiazepines; Double-Blind Method; Droperidol; Drug Thera | 2013 |
Intravenous droperidol or olanzapine as an adjunct to midazolam for the acutely agitated patient: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Benzodiazepines; Double-Blind Method; Droperidol; Drug Thera | 2013 |
Intravenous droperidol or olanzapine as an adjunct to midazolam for the acutely agitated patient: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Benzodiazepines; Double-Blind Method; Droperidol; Drug Thera | 2013 |
Intravenous droperidol or olanzapine as an adjunct to midazolam for the acutely agitated patient: a multicenter, randomized, double-blind, placebo-controlled clinical trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Benzodiazepines; Double-Blind Method; Droperidol; Drug Thera | 2013 |
Intranasal midazolam vs rectal diazepam in acute childhood seizures.
Topics: Acute Disease; Administration, Intranasal; Anticonvulsants; Child; Child, Preschool; Diazepam; Epile | 2006 |
Midazolam in treatment of various types of seizures in children.
Topics: Acute Disease; Anticonvulsants; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Injection | 1997 |
Intranasal midazolam as a treatment of autonomic crisis in patients with familial dysautonomia.
Topics: Acute Disease; Administration, Intranasal; Adolescent; Child; Dysautonomia, Familial; Emergency Medi | 2000 |
Cardiovascular response and stress reaction to flumazenil injection in patients under infusion with midazolam.
Topics: Acute Disease; Adolescent; Adult; Aged; Antidotes; Conscious Sedation; Consciousness; Drug Monitorin | 2000 |
The use of anxiolytic and parasympathomimetic agents in the treatment of postoperative urinary retention following anorectal surgery. A prospective, randomized, double-blind study.
Topics: Acute Disease; Adolescent; Adult; Anal Canal; Bethanechol; Bethanechol Compounds; Double-Blind Metho | 1989 |
Misuse of midazolam.
Topics: Acute Disease; Aggression; Clinical Trials as Topic; Humans; Midazolam; Psychomotor Agitation; Psych | 1988 |
28 other studies available for midazolam and Acute Disease
| Article | Year |
|---|---|
Sedation Practices for Lumbar Punctures in Patients With Acute Lymphoblastic Leukemia: A Multicenter Retrospective Study Using Pediatric Health Information Systems.
Topics: Acute Disease; Adolescent; Anesthesia; Anesthetics, Local; Child; Child, Preschool; Conscious Sedati | 2022 |
Sedation with Propofol During Catheter-Directed Thrombolysis for Acute Submassive Pulmonary Embolism Is Associated with Increased Mortality.
Topics: Acute Disease; Adult; Aged; Anesthetics, Intravenous; Female; Fentanyl; Fibrinolytic Agents; Florida | 2019 |
Effects of midazolam combined with sufentanil on injury and expression of HMGB1 and NF-κB in rats with pancreatitis.
Topics: Acute Disease; Administration, Oral; Animals; Disease Models, Animal; Drug Combinations; HMGB1 Prote | 2020 |
The cost effectiveness of licensed oromucosal midazolam (Buccolam(®)) for the treatment of children experiencing acute epileptic seizures: an approach when trial evidence is limited.
Topics: Acute Disease; Administration, Buccal; Administration, Rectal; Child; Cost-Benefit Analysis; Decisio | 2013 |
Prognostic factors for acute encephalopathy with bright tree appearance.
Topics: Acute Disease; Anti-Anxiety Agents; Brain; Brain Diseases; Child; Child, Preschool; Creatinine; Diaz | 2015 |
The effect of tracheotomy on drug consumption in patients with acute aneurysmal subarachnoid hemorrhage: an observational study.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Cerebrovascular Circulation; | 2015 |
Elimination half-life of alpha-pyrrolidinovalerophenone in an acute non-fatal intoxication.
Topics: Acute Disease; Administration, Intravenous; Central Nervous System Stimulants; Dose-Response Relatio | 2016 |
[Rhabdomyolysis in severe acute asthma].
Topics: Acidosis; Acute Disease; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Combined Modal | 2009 |
Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Animals; Area Under Curve; Child; Cycl | 2009 |
A comparison of midazolam nasal spray and diazepam rectal solution for the residential treatment of seizure exacerbations.
Topics: Acute Disease; Administration, Intranasal; Administration, Rectal; Benzodiazepines; Diazepam; Drug A | 2010 |
Dancing with "death": p-methoxyamphetamine overdose and its acute management.
Topics: Acute Disease; Adult; Amphetamines; Chromatography, Gas; Drug Overdose; Female; Glasgow Coma Scale; | 2003 |
Endogenous distress in ventilated full-term newborns with acute respiratory failure.
Topics: Acute Disease; Analgesia; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intens | 2004 |
Buccal midazolam as rescue therapy for acute seizures.
Topics: Acute Disease; Administration, Buccal; Administration, Intranasal; Administration, Rectal; Anticonvu | 2005 |
Acute encephalitis with refractory, repetitive partial seizures: case reports of this unusual post-encephalitic epilepsy.
Topics: Acute Disease; Anti-Inflammatory Agents; Anticonvulsants; Brain; Cell Count; Cerebrospinal Fluid; Ch | 2007 |
Prospective audit of emergency department transit times associated with entonox analgesia for reduction of the acute, traumatic dislocated shoulder.
Topics: Acute Disease; Analgesia; Analgesics; Anesthetics, Combined; Conscious Sedation; Drug Utilization; E | 2007 |
Acute myoclonus following spinal anaesthesia.
Topics: Acute Disease; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Intr | 2008 |
Energy expenditure and withdrawal of sedation in severe head-injured patients.
Topics: Acute Disease; Adult; Blood Pressure; Craniocerebral Trauma; Energy Metabolism; Fentanyl; Glasgow Co | 1994 |
Conscious sedation for pediatric orthopaedic emergencies.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Conscious Sedation; Emergencies; Female; Fentany | 1996 |
Nasal rather than rectal benzodiazepines in the management of acute childhood seizures?
Topics: Acute Disease; Administration, Intranasal; Administration, Rectal; Adolescent; Anti-Anxiety Agents; | 1996 |
Subcutaneous midazolam for acute hemorrhage in patients with advanced cancer.
Topics: Acute Disease; Hemorrhage; Humans; Hypnotics and Sedatives; Infusions, Parenteral; Midazolam; Neopla | 1998 |
Home and hospital treatment of acute seizures in children with nasal midazolam.
Topics: Acute Disease; Administration, Rectal; Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepa | 1999 |
Management of acute psychosis.
Topics: Acute Disease; Benzodiazepines; Health Services Accessibility; Humans; Injections, Intramuscular; Lo | 2000 |
Temporary bilateral blindness after acute lidocaine toxicity.
Topics: Acute Disease; Adult; Anesthetics, Local; Blindness; Female; Fractures, Bone; GABA Modulators; Hand | 2002 |
Acute dystonia induced by midazolam and abolished by flumazenil.
Topics: Acute Disease; Adolescent; Dystonia; Flumazenil; Humans; Male; Midazolam | 1990 |
Acute benzodiazepine withdrawal after midazolam in children.
Topics: Acute Disease; Child; Humans; Infant; Midazolam; Substance Withdrawal Syndrome | 1990 |
Acute benzodiazepine withdrawal syndrome after midazolam infusions in children.
Topics: Acute Disease; Akathisia, Drug-Induced; Child; Child, Preschool; Cognition Disorders; Confusion; Fem | 1989 |
Use of midazolam hydrochloride in the acutely agitated patient manifesting violent behavior.
Topics: Acute Disease; Emergencies; Humans; Midazolam; Psychomotor Agitation; Violence | 1987 |
Midazolam in acute psychotic patients with hyperarousal.
Topics: Acute Disease; Adolescent; Adult; Emergency Services, Psychiatric; Female; Humans; Male; Midazolam; | 1987 |