midazolam has been researched along with Acidosis in 6 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients receiving midazolam had a more than doubled risk of respiratory depression as mirrored by hypercapnia and acidosis, but not hypoxemia." | 7.88 | Midazolam addition to analgosedation for pulmonary vein isolation may increase risk of hypercapnia and acidosis. ( Bürkle, G; Ehrlich, JR; Feurich, F; Kaess, BM, 2018) |
| "Patients receiving midazolam had a more than doubled risk of respiratory depression as mirrored by hypercapnia and acidosis, but not hypoxemia." | 3.88 | Midazolam addition to analgosedation for pulmonary vein isolation may increase risk of hypercapnia and acidosis. ( Bürkle, G; Ehrlich, JR; Feurich, F; Kaess, BM, 2018) |
| "Midazolam kinetics was simultaneously determined in plasma and brain using striatal microdialysis." | 1.33 | Cerebral and plasma kinetics of a high dose of midazolam and correlations with its respiratory effects in rats. ( Baud, FJ; Borron, SW; Boschi, G; Declèves, X; Galliot-Guilley, M; Lesguillons, N; Megarbane, B; Monier, C; Risède, P; Trout, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaess, BM | 1 |
| Feurich, F | 1 |
| Bürkle, G | 1 |
| Ehrlich, JR | 1 |
| Awab, A | 1 |
| Alilou, M | 1 |
| El Moussaoui, R | 1 |
| El Hijri, A | 1 |
| Azzouzi, A | 1 |
| Megarbane, B | 1 |
| Lesguillons, N | 1 |
| Galliot-Guilley, M | 1 |
| Borron, SW | 1 |
| Trout, H | 1 |
| Declèves, X | 1 |
| Risède, P | 1 |
| Monier, C | 1 |
| Boschi, G | 1 |
| Baud, FJ | 1 |
| Matsuda, M | 1 |
| Matsumoto, S | 1 |
| Noguchi, M | 1 |
| Isshiki, A | 1 |
| Watanabe, Y | 1 |
| Pepperman, ML | 1 |
| Macrae, D | 1 |
| Noble, WH | 1 |
| Baker, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651] | Phase 1 | 20 participants (Actual) | Interventional | 2013-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for midazolam and Acidosis
| Article | Year |
|---|---|
Midazolam addition to analgosedation for pulmonary vein isolation may increase risk of hypercapnia and acidosis.
Topics: Acidosis; Aged; Anesthetics, Intravenous; Drug Therapy, Combination; Female; Fentanyl; Follow-Up Stu | 2018 |
[Rhabdomyolysis in severe acute asthma].
Topics: Acidosis; Acute Disease; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Combined Modal | 2009 |
Cerebral and plasma kinetics of a high dose of midazolam and correlations with its respiratory effects in rats.
Topics: Acidosis; Animals; Bicarbonates; Blood Gas Analysis; Brain; Chromatography, High Pressure Liquid; Ha | 2005 |
[Effects of intravenous anesthetics on acidosis induced apoptosis in primary brain cell culture].
Topics: Acidosis; Anesthetics, Intravenous; Animals; Apoptosis; Brain; Calcium; Cells, Cultured; Female; Hum | 2007 |
A comparison of propofol and other sedative use in paediatric intensive care in the United Kingdom.
Topics: Acidosis; Adolescent; Child; Child, Preschool; Female; Humans; Hypnotics and Sedatives; Infant; Infu | 1997 |
MAO inhibitors and coronary artery surgery: a patient death.
Topics: Acidosis; Anesthesia, Intravenous; Angina, Unstable; Cause of Death; Coronary Artery Bypass; Fentany | 1992 |