midazolam and Ache
midazolam has been researched along with Ache in 323 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the incidence of pain upon injection of 1% propofol (Propofol-Lipuro 1%, B." | 10.21 | [Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides]. ( Ayuso, MA; Fernández, J; Gomar, C; Luis, M; Sala, X, 2004) |
| "The addition of gabapentin to moderate sedation during D&E did not result in lower maximum recalled procedural pain." | 9.69 | Gabapentin as an adjunct for pain management during dilation and evacuation: A double-blind randomized controlled trial. ( Brant, AR; Floyd, S; Lotke, PS; Reeves, MF; Scott, RK; Tefera, E; Ye, PP, 2023) |
| " Sedation with rectal midazolam in adult women before UDS is safe and effective in reducing pain but is not effective in reducing stress and increasing cooperation." | 9.69 | Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial. ( Hassannejad, R; Hayrabedian, A; Mazdak, H; Mirzaei, M; Mohammadi Sichani, M; Saberi, N; Zargham, M, 2023) |
| "This work focused on functional connectivity changes under midazolam and ketamine sedation during performance of a memory task, with the periodic experience of pain." | 9.69 | Brain connectivity under light sedation with midazolam and ketamine during task performance and the periodic experience of pain: Examining concordance between different approaches for seed-based connectivity analysis. ( Aizenstein, HJ; Burlew, AC; Fiez, JA; Ibinson, JW; Smith, CT; Vogt, KM, 2023) |
| "To investigate the possible advantage of topical lidocaine and intravenous midazolam in preventing spasm and pain related to the radial artery." | 9.69 | Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. ( Elattar, MM; Haseeb, WA; NBiomy, R; Salama, MK, 2023) |
| "Painful stimulation during light sedation with midazolam, but not ketamine, can be accompanied by increased coherence in brain connectivity, even though details are less likely to be recollected as explicit memories." | 9.41 | Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain. ( Aizenstein, HJ; Citro, AT; Fiez, JA; Ibinson, JW; Karim, HT; Mahajan, A; Norton, CM; Popov, V; Reder, LM; Smith, CT; Vogt, KM, 2021) |
| " The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration." | 9.34 | The effectiveness of topical lidocaine in relieving pain related to intranasal midazolam sedation: a randomized, placebo-controlled clinical trial. ( Khalil, W; Raslan, N, 2020) |
| "Premedication with 2 mg of IV midazolam reduces pain of NGT insertion in ED patients without the need for full procedural sedation." | 9.22 | Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study). ( Buinewicz, JD; Freeman, K; Gutierrez, K; Manning, CT; O'Keefe, MF; Sewatsky, TP; Zgonis, E, 2016) |
| "The incidence of propofol injection pain is high in children, but no methods have been found to suppress it completely." | 9.20 | Preemptive dexmedetomidine to prevent propofol injection pain in children. ( Dong, C; Lu, Y; Yu, J; Zhang, Y, 2015) |
| "To investigate the influence of the midazolam sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients in intensive care unit (ICU)." | 9.20 | [The influence of the sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients]. ( An, Y; Feng, Y; Liu, D; Lyu, J, 2015) |
| "To compare remifentanil and morphine-midazolam for use in nonurgent endotracheal intubation in neonates." | 9.19 | Remifentanil versus morphine-midazolam premedication on the quality of endotracheal intubation in neonates: a noninferiority randomized trial. ( Avino, D; De Villé, A; Johansson, AB; Zhang, WH, 2014) |
| "The addition of 3% sevoflurane at the time of preoxygenation for 1 min along with routine use of lidocaine-tourniquet completely prevented pain upon propofol injection, whereas sevoflurane by itself provided similar analgesia to premixed lidocaine with propofol." | 9.15 | Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011) |
| " However, remifentanil continuous infusion proved to offer significantly more stable pain control compared with the currently used combination fentanyl-midazolam." | 9.14 | Analgesia during abdominal aortic aneurysm endovascular repair: remifentanil vs. fentanyl-midazolam--a randomized controlled trial. ( Barbieri, A; Bonfreschi, V; Coppi, G; D'Amico, R; Giuliani, E; Malagnino, FC; Navi, A; Silingardi, R, 2009) |
| "On the basis of a small number of case studies, IV propofol has been advocated for the treatment of chronic daily headache (CDH)." | 9.14 | The effect of single-dose propofol injection on pain and quality of life in chronic daily headache: a randomized, double-blind, controlled trial. ( Dick, BD; Gray, DP; Jamieson-Lega, KI; Rashiq, S; Simmonds, MK; Sobolev, IA; Stewart, BJ, 2009) |
| "In this prospective, randomized, double-blind, controlled trial, our primary objective was to assess the effect of a 3 : 1 mixture of propofol and thiopental in reducing pain on injection in children." | 9.14 | The effect of a 3 : 1 volume mixture of propofol 1% and thiopental 2.5% in reducing the pain on injection of propofol in children. ( Ajala, AM; Blackwelder, B; Fahringer, DL; Goodwin, SR; Gurgis, FS; Warde, MK; Ye, G, 2010) |
| "The intent of our study was to compare the effects of dexmedetomidine versus midazolam on perioperative hemodynamics, sedation, pain, satisfaction and recovery scores during colonoscopy." | 9.14 | A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation. ( Budak, ET; Dagli, G; Dere, K; Filiz, AI; Ozkan, S; Sucullu, I; Yeyen, S, 2010) |
| "A study involving the use of a mixture of ketamine and midazolam delivered via patient-controlled analgesia (PCA) device was trialed to assess its effectiveness in reducing pain associated with repeated burns dressings in an adult population." | 9.13 | Ketamine and midazolam delivered by patient-controlled analgesia in relieving pain associated with burns dressings. ( MacPherson, RD; Penfold, J; Woods, D, 2008) |
| "To compare intravenous titrated midazolam 5-10 mg and inhaled Entonox in addition to local anaesthesia in order to identify which agent provides optimum pain relief." | 9.13 | Midazolam in conjunction with local anaesthesia is superior to Entonox in providing pain relief during bone marrow aspirate and trephine biopsy. ( Allotey, D; Bratby, L; Chakupurakal, G; de la Rue, J; Delgado, J; Holder, K; Milligan, DW; Nikolousis, E; Pitchapillai, S, 2008) |
| "Conscious sedation with rectally applied S(+)-ketamine and Midazolam allows safe and painless dressing changes after heat injuries in children." | 9.11 | Conscious sedation: Off-label use of rectal S(+)-ketamine and midazolam for wound dressing changes in paediatric heat injuries. ( Heinrich, M; Muensterer, OJ; Till, H; Wetzstein, V, 2004) |
| "To test the hypothesis that remifentanil, because of its favorable pharmacokinetic properties, would be advantageous to use in combination with midazolam to provide analgesia and sedation during brief painful procedures." | 9.09 | Conscious sedation with remifentanil and midazolam during brief painful procedures in children. ( Litman, RS, 1999) |
| "Parents and nurses reported reduced anxiety, discomfort, and procedure problems for children in the midazolam group and would prefer the same medication at next procedure." | 9.09 | Midazolam nasal spray reduces procedural anxiety in children. ( Andréasson, S; Gordh, T; Kreuger, A; Ljungman, G; Sörensen, S, 2000) |
| " Our aim was to compare EMLA and placebo to assess the efficacy of EMLA in decreasing the pain of venipuncture in children premedicated with oral midazolam 0." | 9.08 | [Efficacy of the EMLA cream in the reduction of pain caused by venipuncture in children premedicated with oral midazolam]. ( Cassinello, F; de Stefano, J; Herrero, E; Martín-Celemín, R; Palencia, J; Pérez-Gallardo, A, 1995) |
| "Intra- and postoperative wake-up tests were performed together with somatosensory cortical evoked potentials (SCEPs) monitoring in 40 patients randomized to either midazolam (M) or propofol (P) infusions for scoliosis surgery." | 9.08 | Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests. ( Hesselbjerg, L; Koscielniak-Nielsen, ZJ; Stens-Pedersen, HL, 1998) |
| "To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group." | 9.08 | [Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998) |
| "The purpose of the present study is to compare the injection pain of propofol with that of benzodiazepines when used for intravenous sedation." | 9.08 | Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines. ( Fukuda, K; Ichinohe, T; Kaneko, Y; Kasahara, M; Mamiya, H; Noma, T, 1998) |
| "In a randomised, double-blind, cross-over study on 20 healthy human volunteers, the effect of intravenous midazolam on pain tolerance using the 'submaximum effort tourniquet technique' is described." | 9.07 | An investigation of the effect of midazolam on the pain experience. ( Coulthard, P; Rood, JP, 1992) |
| "To investigate the effect of midazolam on pain in lumbar disc herniation model rats based on p38 MAPK signaling pathway." | 8.31 | [Analysis of the effect of midazolam on pain in a rat model of lumbar disc herniation based on the p38 MAPK signaling pathway]. ( Liu, J; Liu, S; Liu, SM; Ye, YJ, 2023) |
| "The impact of midazolam on the overall performance of morphine therapy for pain in ventilated neonates with respiratory distress syndrome (RDS) has never been investigated." | 8.02 | Clinical and Economic Evaluation of the Impact of Midazolam on Morphine Therapy for Pain Relief in Critically Ill Ventilated Infants with Respiratory Distress Syndrome. ( Abdelaal, M; Abounahia, FF; Abushanab, D; Al-Badriyeh, D; Alsoukhni, O, 2021) |
| "The aims of this study were to quantify the pain and distress associated with the administration of intranasal (IN) midazolam in young children using 4 observational measures and to evaluate the degree of validity of these measures." | 8.02 | Quantification of Pain and Distress Associated With Intranasal Midazolam Administration in Children and Evaluation of Validity of Four Observational Measures. ( Bregstein, JS; Dayan, PS; Flores-Sanchez, PL; Ieni, M; O'Connell, NC; Shen, ST; Tsze, DS, 2021) |
| "We studied the role of a low-dose intravenous (IV) ketamine-midazolam combination in the management of severe painful sickle cell crisis." | 7.80 | The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease. ( Faris, AS; Kausalya, R; Tawfic, QA, 2014) |
| " Since 2005 to 2007, we evaluated the safety and efficacy of ketamine to control pain induced by diagnostic procedures in pediatric oncology patients." | 7.75 | [Sedation using ketamine for pain procedures in Pediatric Oncology.]. ( Bernard, F; Ricard, C; Tichit, R; Troncin, R, 2009) |
| "Eight right-handed male volunteers underwent fMRI combined with a thermal pain conditioning paradigm and midazolam (30 mug/kg) or saline administration on different occasions, with order randomized across volunteers." | 7.74 | The anxiolytic effects of midazolam during anticipation to pain revealed using fMRI. ( Lujan, BJ; Peskett, GD; Rogers, R; Schweinhardt, P; Tracey, I; Wise, RG, 2007) |
| " The questionnaire retrieved the endoscopists' experience regarding patients' discomfort or pain under sedation with midazolam, their wish for better sedative agents, their preferred sedative regimens, their medical specialty and their professional experience." | 7.74 | Midazolam-pain, but one cannot remember it: a survey among Southern German endoscopists. ( Frimberger, E; Hollweck, R; Schmid, RM; von Delius, S, 2007) |
| "In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats." | 7.72 | Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain. ( Hanaoka, K; Nishiyama, T, 2003) |
| "Spinally-administered midazolam, a benzodiazepine, and clonidine, an alpha2-adrenergic receptor agonist, have significant synergistic effects on thermally-induced acute and formalin-induced inflammatory pain." | 7.71 | The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats. ( Hanaoka, K; Nishiyama, T, 2001) |
| "We evaluated the safety and efficacy of midazolam-ketamine association to control pain induced by diagnostic procedures in paediatric oncology patients." | 7.70 | Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study. ( Granry, JC; Le Moine, P; Monrigal, JP; Pellier, I; Rialland, X; Rod, B, 1999) |
| "Patients with renal lithiasis were included and were randomized to Group A (basal analgesia: midazolam (1 mg), fentanyl (0." | 7.11 | Value of Music and Nitrous Oxide for Pain Control during Extracorporeal Shock Wave Lithotripsy (ESWL). ( Alcoba-García, MP; Bueno-Serrano, G; González-Enguita, C; González-López, R; Llanos-Jiménez, L; Mahillo-Fernández, I; Tabares-Jiménez, J, 2022) |
| "The reduction in allodynia evoked by light stroking was statistically significant only for alfentanil." | 6.68 | Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. ( Bennett, GJ; Gracely, RH; Max, MB; Park, KM; Robinovitz, E, 1995) |
| "Midazolam was found to be the drug of preference for the majority of patients." | 6.67 | Midazolam versus fentanyl as premedication for painful procedures in children with cancer. ( Conner, K; Dickson, N; Luzins, J; McGorray, S; Reilly, K; Sandler, ES; Weyman, C, 1992) |
| "Alfentanil was used as an adjuvant to midazolam for analgesia in thirty outpatients undergoing colonoscopy." | 6.67 | Pain relief for outpatient colonoscopy: a comparison of alfentanil with fentanyl. ( Holloway, AM; Logan, DA, 1990) |
| "To study the incidence of pain upon injection of 1% propofol (Propofol-Lipuro 1%, B." | 6.21 | [Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides]. ( Ayuso, MA; Fernández, J; Gomar, C; Luis, M; Sala, X, 2004) |
| "The addition of gabapentin to moderate sedation during D&E did not result in lower maximum recalled procedural pain." | 5.69 | Gabapentin as an adjunct for pain management during dilation and evacuation: A double-blind randomized controlled trial. ( Brant, AR; Floyd, S; Lotke, PS; Reeves, MF; Scott, RK; Tefera, E; Ye, PP, 2023) |
| " Sedation with rectal midazolam in adult women before UDS is safe and effective in reducing pain but is not effective in reducing stress and increasing cooperation." | 5.69 | Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial. ( Hassannejad, R; Hayrabedian, A; Mazdak, H; Mirzaei, M; Mohammadi Sichani, M; Saberi, N; Zargham, M, 2023) |
| "To investigate the possible advantage of topical lidocaine and intravenous midazolam in preventing spasm and pain related to the radial artery." | 5.69 | Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm. ( Elattar, MM; Haseeb, WA; NBiomy, R; Salama, MK, 2023) |
| " Compared with midazolam, dexmedetomidine was favorable in reducing both emergence delirium and pain in the postoperative care unit, and both clonidine and dexmedetomidine reduced anxiety in the postoperative care unit." | 5.69 | Postoperative recovery in preschool-aged children: A secondary analysis of a randomized controlled trial comparing premedication with midazolam, clonidine, and dexmedetomidine. ( Bromfalk, Å; Engström, Å; Hultin, M; Myrberg, T; Walldén, J, 2023) |
| "The combination uses of midazolam and pethidine for sedation resulted in significant improvements in the pain, blood pressure, additional use of midazolam, and safety during bronchoscopy among patients." | 5.51 | Randomized single-blind comparative study of the midazolam/pethidine combination and midazolam alone during bronchoscopy. ( Furukawa, K; Hazama, D; Katsurada, M; Katsurada, N; Kiriu, T; Kobayashi, K; Mimura, C; Nagano, T; Nishimura, Y; Otoshi, T; Sato, H; Tachihara, M; Takata, N; Yamamoto, M; Yasuda, Y; Yoshioka, J; Yumura, M, 2022) |
| "5 ng/mL to keep patient comfort with acceptable pain (remaining moveless), and mean arterial pressure and heart rate within baseline levels ± 30%, and using intermittent bolus midazolam to keep the Observer's Assessment of Alertness/Sedation scale between 2 and 4." | 5.51 | Comparison of 2 effect-site concentrations of remifentanil with midazolam during transrectal ultrasound-guided prostate biopsy under procedural analgesia and sedation: A randomized controlled study. ( Chan, SM; Chen, CL; Huang, RC; Huang, YH; Lai, HC; Lin, BF; Wu, KL; Wu, ZF, 2022) |
| "Painful stimulation during light sedation with midazolam, but not ketamine, can be accompanied by increased coherence in brain connectivity, even though details are less likely to be recollected as explicit memories." | 5.41 | Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain. ( Aizenstein, HJ; Citro, AT; Fiez, JA; Ibinson, JW; Karim, HT; Mahajan, A; Norton, CM; Popov, V; Reder, LM; Smith, CT; Vogt, KM, 2021) |
| " The objective of the current study was to evaluate the effectiveness of topical lidocaine in relieving pain related to INM administration." | 5.34 | The effectiveness of topical lidocaine in relieving pain related to intranasal midazolam sedation: a randomized, placebo-controlled clinical trial. ( Khalil, W; Raslan, N, 2020) |
| "midazolam were significantly reversed by i." | 5.31 | Effects of midazolam in the spinal nerve ligation model of neuropathic pain in rats. ( Dickenson, AH; Kontinen, VK, 2000) |
| "To assess whether inhaled nitrous oxide is noninferior to intravenous (IV) sedation for pain control during outpatient surgical abortion between 12 and 16 weeks of gestation." | 5.27 | Nitrous Oxide Compared With Intravenous Sedation for Second-Trimester Abortion: A Randomized Controlled Trial. ( Espey, E; Pitotti, J; Sheeder, J; Singh, RH; Teal, S; Thaxton, L, 2018) |
| "Premedication with 2 mg of IV midazolam reduces pain of NGT insertion in ED patients without the need for full procedural sedation." | 5.22 | Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study). ( Buinewicz, JD; Freeman, K; Gutierrez, K; Manning, CT; O'Keefe, MF; Sewatsky, TP; Zgonis, E, 2016) |
| "Based on the present data, adding haloperidol plus midazolam to morphine for pain management improved pain scores and lowered morphine consumption among opium-dependent patients." | 5.22 | Midazolam Plus Haloperidol as Adjuvant Analgesics to Morphine in Opium Dependent Patients: A Randomized Clinical Trial. ( Afzalimoghaddam, M; Edalatifard, M; Isavi, N; Karimialavijeh, E; Momeni, M; Nejati, A, 2016) |
| "Pethidine with midazolam-induced conscious sedation for pain relief during transvaginal oocyte retrieval for in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) procedures is associated with residual pain and oversedation." | 5.20 | Patient-Controlled Remifentanil Analgesia as Alternative for Pethidine with Midazolam During Oocyte Retrieval in IVF/ICSI Procedures: A Randomized Controlled Trial. ( Boer, C; Douwenga, WM; Hompes, PG; Lier, MC; Mijatovic, V; Schats, R; Yilmaz, F, 2015) |
| "The incidence of propofol injection pain is high in children, but no methods have been found to suppress it completely." | 5.20 | Preemptive dexmedetomidine to prevent propofol injection pain in children. ( Dong, C; Lu, Y; Yu, J; Zhang, Y, 2015) |
| "The aim of the study was to determine whether or not dexmedetomidine- (DEX-) based intravenous infusion in dental implantation can provide better sedation and postoperative analgesia via suppressing postoperative inflammation and oxidative stress." | 5.20 | Dexmedetomidine Analgesia Effects in Patients Undergoing Dental Implant Surgery and Its Impact on Postoperative Inflammatory and Oxidative Stress. ( Cheung, CW; Li, S; Qian, L; Wu, Y; Yang, Y; Yao, Y; Yu, C, 2015) |
| "The sedative effects of dexmedetomidine in the ICU patients treated with ventilator bundle treatment are satisfactory, and it can shorten the duration of mechanical ventilation, extubation time and length of ICU stay, reduce the incidence of delirium." | 5.20 | [A study of using dexmedetomidine in ventilator bundle treatment in an ICU]. ( Dong, C; Li, J; Song, R; Yang, J, 2015) |
| "To investigate the influence of the midazolam sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients in intensive care unit (ICU)." | 5.20 | [The influence of the sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients]. ( An, Y; Feng, Y; Liu, D; Lyu, J, 2015) |
| "No difference was found in pain assessment during local anaesthetic injection between the group treated with midazolam and ketamine, and the group treated with midazolam alone." | 5.19 | A double-blind, randomised, placebo-controlled trial of oral midazolam plus oral ketamine for sedation of children during laceration repair. ( Assa, A; Barkan, S; Berkovitch, S; Breitbart, R; Brenner-Zada, G; Feldon, M; Kozer, E; Shavit, I; Toledano, M, 2014) |
| "There was no significant difference in the total dose of midazolam added, patient's pain assessment and satisfaction from the anesthesia and the procedure, duration of endoscopies, or the time to cecal intubation between the esophagogastroduodenoscopy first and colonoscopy first groups." | 5.19 | Comparison of procedural sequence in same-day consecutive bidirectional endoscopy using moderate sedation: a prospective randomized study. ( Bardan, E; Carter, D; Eliakim, R; Goldstein, S; Lahat, A; Papageorgiou, NP, 2014) |
| "To compare remifentanil and morphine-midazolam for use in nonurgent endotracheal intubation in neonates." | 5.19 | Remifentanil versus morphine-midazolam premedication on the quality of endotracheal intubation in neonates: a noninferiority randomized trial. ( Avino, D; De Villé, A; Johansson, AB; Zhang, WH, 2014) |
| " Before fracture reduction, children 3 to 17 years of age randomly received 2% lidocaine (L) or normal saline (NS) into the hematoma of their fracture site during sedation with intravenous ketamine and midazolam." | 5.19 | Evaluating the hematoma block as an adjunct to procedural sedation for closed reduction of distal forearm fractures. ( Constantine, E; Eberson, CP; Linakis, JG; Machan, JT; Steele, DW; Tsze, DS, 2014) |
| " access, and blood sampling pain and stress affect hormone values, treatment with N(2)O or midazolam influence the glucose and stress hormone levels differently." | 5.16 | Effects of midazolam and nitrous oxide on endocrine and metabolic measurements in children. ( Ekbom, K; Jakobsson, J; Kalman, S; Marcus, C, 2012) |
| "Acetaminophen alone may not be as effective in reducing pain-related physiological and behavioral changes as acetaminophen plus codeine or ibuprofen plus midazolam during diagnostic tympanocentesis." | 5.15 | Pain management in young children undergoing diagnostic tympanocentesis. ( Chandra, A; Colborn, DK; Hoberman, A; Hooper, EG; Kurs-Lasky, M; Reis, EC; Rockette, HE; Shaikh, N, 2011) |
| "To compare the efficacy of sublingual midazolam with oral morphine versus that of oral morphine with placebo in a paediatric population attending an emergency department (ED) with acute long-bone fractures." | 5.15 | Comparison of a morphine and midazolam combination with morphine alone for paediatric displaced fractures: a randomized study. ( Chappuy, H; Chéron, G; Giraud, C; Tréluyer, JM; Wille-Ledon, C, 2011) |
| "The addition of 3% sevoflurane at the time of preoxygenation for 1 min along with routine use of lidocaine-tourniquet completely prevented pain upon propofol injection, whereas sevoflurane by itself provided similar analgesia to premixed lidocaine with propofol." | 5.15 | Sevoflurane to alleviate pain on propofol injection. ( Ali, MS; DeSousa, K, 2011) |
| "Entonox provides better pain relief and faster recovery than midazolam-fentanyl and so is more effective for colonoscopy." | 5.14 | Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy. ( Culbert, B; Duthie, GS; Gardiner, A; Hughes, M; Maslekar, S, 2009) |
| " However, remifentanil continuous infusion proved to offer significantly more stable pain control compared with the currently used combination fentanyl-midazolam." | 5.14 | Analgesia during abdominal aortic aneurysm endovascular repair: remifentanil vs. fentanyl-midazolam--a randomized controlled trial. ( Barbieri, A; Bonfreschi, V; Coppi, G; D'Amico, R; Giuliani, E; Malagnino, FC; Navi, A; Silingardi, R, 2009) |
| " There are many methods for pain relief and to treat discomfort during the procedure but we compared the efficacy of intravenous (IV) midazolam for pain control." | 5.14 | Transrectal ultrasound-guided prostatic biopsy: midazolam, the ideal analgesic. ( Bhandari, Y; Gaitonde, S; Kharbanda, S; Mankeshwar, R; Patil, M; Shrimali, P; Srinivas, V, 2009) |
| "On the basis of a small number of case studies, IV propofol has been advocated for the treatment of chronic daily headache (CDH)." | 5.14 | The effect of single-dose propofol injection on pain and quality of life in chronic daily headache: a randomized, double-blind, controlled trial. ( Dick, BD; Gray, DP; Jamieson-Lega, KI; Rashiq, S; Simmonds, MK; Sobolev, IA; Stewart, BJ, 2009) |
| "In this prospective, randomized, double-blind, controlled trial, our primary objective was to assess the effect of a 3 : 1 mixture of propofol and thiopental in reducing pain on injection in children." | 5.14 | The effect of a 3 : 1 volume mixture of propofol 1% and thiopental 2.5% in reducing the pain on injection of propofol in children. ( Ajala, AM; Blackwelder, B; Fahringer, DL; Goodwin, SR; Gurgis, FS; Warde, MK; Ye, G, 2010) |
| "The intent of our study was to compare the effects of dexmedetomidine versus midazolam on perioperative hemodynamics, sedation, pain, satisfaction and recovery scores during colonoscopy." | 5.14 | A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation. ( Budak, ET; Dagli, G; Dere, K; Filiz, AI; Ozkan, S; Sucullu, I; Yeyen, S, 2010) |
| "During the first 12 hr following the procedures, patients experienced significantly less vomiting/retching and less disruption of activity while receiving ondansetron, and recorded significantly lower pain scores while receiving fentanyl." | 5.13 | Pediatric oncology sedation trial (POST): A double-blind randomized study. ( Barr, RD; Buckley, N; Korz, L; Lappan, J; Nagel, K; Willan, AR, 2008) |
| "A study involving the use of a mixture of ketamine and midazolam delivered via patient-controlled analgesia (PCA) device was trialed to assess its effectiveness in reducing pain associated with repeated burns dressings in an adult population." | 5.13 | Ketamine and midazolam delivered by patient-controlled analgesia in relieving pain associated with burns dressings. ( MacPherson, RD; Penfold, J; Woods, D, 2008) |
| "To compare intravenous titrated midazolam 5-10 mg and inhaled Entonox in addition to local anaesthesia in order to identify which agent provides optimum pain relief." | 5.13 | Midazolam in conjunction with local anaesthesia is superior to Entonox in providing pain relief during bone marrow aspirate and trephine biopsy. ( Allotey, D; Bratby, L; Chakupurakal, G; de la Rue, J; Delgado, J; Holder, K; Milligan, DW; Nikolousis, E; Pitchapillai, S, 2008) |
| "The routine use of fentanyl and midazolam prior to sheath removal leads to a reduction in pain perception and vasovagal incidence, whilst the routine use of local infiltration during sheath removal should be discouraged as it leads to more pain and a trend to more vasovagal reactions." | 5.12 | Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention. ( French, JK; Juergens, CP; Kiat Ang, C; Leung, DY; Lo, S, 2007) |
| "Conscious sedation with rectally applied S(+)-ketamine and Midazolam allows safe and painless dressing changes after heat injuries in children." | 5.11 | Conscious sedation: Off-label use of rectal S(+)-ketamine and midazolam for wound dressing changes in paediatric heat injuries. ( Heinrich, M; Muensterer, OJ; Till, H; Wetzstein, V, 2004) |
| "The pain and distress ratings of patients undergoing BMAs (n = 73) and LPs (n = 105) were examined in a comparison of 3 different interventions: (1) a topical eutectic mixture of lidocaine and prilocaine (EMLA cream), (2) oral midazolam and EMLA cream, or (3) propofol/fentanyl general anesthesia." | 5.10 | Pain and distress from bone marrow aspirations and lumbar punctures. ( Doran, NH; Frost, JD; Holdsworth, MT; Mathew, P; Moro, MA; Pankey, JM; Phillips, J; Raisch, DW; Winter, SS, 2003) |
| " Although the visual analog scale, Observer's Assessment of Alertness/Sedation Scale, and State and Trait Anxiety Inventory-State Anxiety test did not show statistically significant differences, the State and Trait Anxiety Inventory-Trait Anxiety score was found to be lower in the music group (group 2) than in the midazolam group (group 1)." | 5.10 | Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy. ( Basar, H; Basar, M; Batislam, E; Ferhat, M; Ozcan, S; Yilmaz, E, 2003) |
| "The addition of a single bolus of meperidine to midazolam improves patient tolerance and lessens pain during colonoscopy without significantly increasing the frequency of side effects or prolonging recovery time." | 5.10 | Single bolus of midazolam versus bolus midazolam plus meperidine for colonoscopy: a prospective, randomized, double-blind trial. ( Imperiali, G; Lenoci, N; Mandelli, G; Meucci, G; Minoli, G; Radaelli, F; Spinzi, G; Strocchi, E; Terreni, N; Terruzzi, V, 2003) |
| "5 years) undergoing midazolam-induced conscious sedation during painful medical procedures to treat hematological or oncological diseases." | 5.10 | Memory in pediatric patients undergoing conscious sedation for aversive medical procedures. ( Dahlquist, LM; Eskenazi, A; Pringle, B, 2003) |
| " Patients in the PCS group had significantly higher pain scores and significantly more recall than those in the midazolam and pethidine group." | 5.10 | Patient-controlled sedation for colonoscopy: a randomized trial comparing patient-controlled administration of propofol and alfentanil with physician-administered midazolam and pethidine. ( Bright, E; Dalgleish, D; Elliott, J; Kimble, J; Roseveare, C; Shepherd, H, 2003) |
| "During a step-up internal atrial defibrillation protocol, intranasal butorphanol decreased or stabilized the value of several pain variables and did not affect fear." | 5.09 | Effect of butorphanol tartrate on shock-related discomfort during internal atrial defibrillation. ( Albert, A; Ayers, GM; Lambert, H; Rodriguez, LM; Smeets, JL; Timmermans, C; Vlaeyen, JW; Wellens, HJ, 1999) |
| "To test the hypothesis that remifentanil, because of its favorable pharmacokinetic properties, would be advantageous to use in combination with midazolam to provide analgesia and sedation during brief painful procedures." | 5.09 | Conscious sedation with remifentanil and midazolam during brief painful procedures in children. ( Litman, RS, 1999) |
| "Oral midazolam significantly reduces anxiety and pain during flexible sigmoidoscopy as assessed by both patients and physicians." | 5.09 | A double-blind placebo controlled trial of oral midazolam as premedication before flexible sigmoidoscopy. ( Chen, ST; Clarkston, WK; Cuddy, PG; Dierenfeldt, WT; Jonnalagadda, SS; Kuganeswaran, E; Pandya, PK; Quiason, SG; Smith, OJ, 1999) |
| "Parents and nurses reported reduced anxiety, discomfort, and procedure problems for children in the midazolam group and would prefer the same medication at next procedure." | 5.09 | Midazolam nasal spray reduces procedural anxiety in children. ( Andréasson, S; Gordh, T; Kreuger, A; Ljungman, G; Sörensen, S, 2000) |
| "Patients' recall of their tolerance to the exam (categorical scale) and pain score were significantly in favor of midazolam at 2 and 24 hours." | 5.09 | Midazolam sedation for upper gastrointestinal endoscopy in older persons: a randomized, double-blind, placebo-controlled study. ( Armenian, B; Christe, C; Herrmann, F; Janssens, JP; Vogt, N, 2000) |
| " Our aim was to compare EMLA and placebo to assess the efficacy of EMLA in decreasing the pain of venipuncture in children premedicated with oral midazolam 0." | 5.08 | [Efficacy of the EMLA cream in the reduction of pain caused by venipuncture in children premedicated with oral midazolam]. ( Cassinello, F; de Stefano, J; Herrero, E; Martín-Celemín, R; Palencia, J; Pérez-Gallardo, A, 1995) |
| " However, the benefit of the most often used combination of intravenous midazolam and pethidine on patient tolerance and pain and its cardiorespiratory risk have not been fully defined." | 5.08 | Sedation and analgesia for colonoscopy: patient tolerance, pain, and cardiorespiratory parameters. ( Fried, M; Froehlich, F; Gonvers, JJ; Hays, RD; Köhler, M; Preisig, M; Schwizer, W; Thorens, J, 1997) |
| " A high incidence of pain with drug injection was noted among patients receiving propofol (80%)." | 5.08 | Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients. ( Ganapathy, S; Gelb, AW; Herrick, IA; Kirkby, J, 1997) |
| " This study was designed to: 1) compare the safety and efficacy of intravenous fentanyl, intravenous fentanyl combined with midazolam, and intramuscular meperidine-promethazine-chlorpromazine (MPC) compound when used for painful emergency department (ED) procedures: and 2) to determine whether the addition of et-CO2 monitoring enabled earlier identification of respiratory depression in this population." | 5.08 | The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department. ( Berns, SD; Boenning, DA; Hart, LS; Houck, CS, 1997) |
| "Intra- and postoperative wake-up tests were performed together with somatosensory cortical evoked potentials (SCEPs) monitoring in 40 patients randomized to either midazolam (M) or propofol (P) infusions for scoliosis surgery." | 5.08 | Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests. ( Hesselbjerg, L; Koscielniak-Nielsen, ZJ; Stens-Pedersen, HL, 1998) |
| "To evaluate the efficacy of continuous administration of 50% nitrous oxide in oxygen for reducing pain during flexible fiberoptic bronchoscopy 32 children aged 3-60 months were randomly assigned to an experimental or a control group." | 5.08 | [Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination]. ( Dupont, D; Garcia, J; Hayem, C; Roure, P, 1998) |
| "The purpose of the present study is to compare the injection pain of propofol with that of benzodiazepines when used for intravenous sedation." | 5.08 | Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines. ( Fukuda, K; Ichinohe, T; Kaneko, Y; Kasahara, M; Mamiya, H; Noma, T, 1998) |
| "In a randomised, double-blind, cross-over study on 20 healthy human volunteers, the effect of intravenous midazolam on pain tolerance using the 'submaximum effort tourniquet technique' is described." | 5.07 | An investigation of the effect of midazolam on the pain experience. ( Coulthard, P; Rood, JP, 1992) |
| "Nitrous oxide is an effective sedative/analgesic for mildly to moderately painful paediatric procedures." | 4.89 | Nitrous oxide provides safe and effective analgesia for minor paediatric procedures--a systematic review. ( Bayat, A; Jacobsson, ML; Pedersen, RS; Steen, NP, 2013) |
| "To investigate the effect of midazolam on pain in lumbar disc herniation model rats based on p38 MAPK signaling pathway." | 4.31 | [Analysis of the effect of midazolam on pain in a rat model of lumbar disc herniation based on the p38 MAPK signaling pathway]. ( Liu, J; Liu, S; Liu, SM; Ye, YJ, 2023) |
| " Multiple demographic and psychosocial factors, as well as perhaps provider bias, play into both a patient's perception of pain and the dosage of fentanyl and midazolam they receive during abortion procedures." | 4.31 | The association of patient age, race, and demographic features on reported pain and sedation dosing during procedural abortion: A retrospective cohort study. ( Howard, M; Lee, J; Makar, E; Pace, L, 2023) |
| " There was a significant decrease in propofol and fentanyl utilization from 24 hours pretracheostomy to 24 hours posttracheostomy in both dose and number of patients receiving these continuous intravenous medications." | 4.12 | Tracheostomy decreases continuous analgesia and sedation requirements. ( Droege, CA; Elson, NC; Goodman, MD; Hayes, HV; Nomellini, V; Pritts, TA; Salvator, A; Singer, KE; Wallen, TE, 2022) |
| "The impact of midazolam on the overall performance of morphine therapy for pain in ventilated neonates with respiratory distress syndrome (RDS) has never been investigated." | 4.02 | Clinical and Economic Evaluation of the Impact of Midazolam on Morphine Therapy for Pain Relief in Critically Ill Ventilated Infants with Respiratory Distress Syndrome. ( Abdelaal, M; Abounahia, FF; Abushanab, D; Al-Badriyeh, D; Alsoukhni, O, 2021) |
| "The aims of this study were to quantify the pain and distress associated with the administration of intranasal (IN) midazolam in young children using 4 observational measures and to evaluate the degree of validity of these measures." | 4.02 | Quantification of Pain and Distress Associated With Intranasal Midazolam Administration in Children and Evaluation of Validity of Four Observational Measures. ( Bregstein, JS; Dayan, PS; Flores-Sanchez, PL; Ieni, M; O'Connell, NC; Shen, ST; Tsze, DS, 2021) |
| "Compared to propofol and general anesthesia, midazolam/fentanyl sedation was associated with an increased periprocedural perception of pain and lower local tumor progression-free survival." | 3.91 | Propofol Compared to Midazolam Sedation and to General Anesthesia for Percutaneous Microwave Ablation in Patients with Hepatic Malignancies: A Single-Center Comparative Analysis of Three Historical Cohorts. ( de Jong, MC; de Vries, JJJ; Geboers, B; Gerçek, CC; Hoedemaker-Boon, CJ; Meijerink, MR; Nieuwenhuizen, S; Puijk, RS; Ruarus, AH; Scheffer, HJ; Thöne-Passchier, DH; van den Tol, PMP; Vroomen, LGPH; Ziedses des Plantes, V, 2019) |
| " Fentanyl, midazolam, and dexmedetomidine were the first choices of agents for analgesic, sedation, and delirium treatment." | 3.85 | A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China. ( Hu, B; Li, JG; Peng, ZY; Rao, X; Wang, J; Zhou, WH, 2017) |
| "Only fentanyl+midazolam significantly attenuated both the clinical pain score and the increase in blood glucose." | 3.81 | Effect of premedication regimen on infant pain and stress response to endotracheal intubation. ( Caldwell, CD; Watterberg, KL, 2015) |
| "Midazolam and ketamine were administered consecutively by intravenous route under cardiorespiratory monitoring for painful procedures of pediatric hematology." | 3.81 | The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology. ( Çakmak, E; Demirsoy, U; Gelen, SA; Sarper, N; Zengin, E, 2015) |
| "We studied the role of a low-dose intravenous (IV) ketamine-midazolam combination in the management of severe painful sickle cell crisis." | 3.80 | The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease. ( Faris, AS; Kausalya, R; Tawfic, QA, 2014) |
| "Morphine is co-administered with adjuvant drugs to treat pain, nausea, vomiting, dyspnoea and delirium in cancer patients." | 3.80 | Analgesic effects of morphine in combination with adjuvant drugs in rats. ( Kaminska, E; Leppert, W; Mikolajczak, P; Okulicz-Kozaryn, I; Szulc, M, 2014) |
| "Considering the potential pain and dissatisfaction of rigid cystoscopic ureteral stent removal, procedures utilizing moderate sedation with midazolam or general anesthesia using propofol without muscle relaxation should be considered." | 3.80 | Pain and satisfaction during rigid cystoscopic ureteral stent removal: a preliminary study. ( Cho, SW; Choi, H; Kim, JH; Kim, MG; Park, SY; Song, D; Song, YS, 2014) |
| "Tramadol is often coadministered subcutaneously with adjuvants to treat pain, nausea/vomiting, dyspnea and delirium in cancer patients." | 3.79 | Analgesic effects of tramadol in combination with adjuvant drugs: an experimental study in rats. ( Kaminska, E; Leppert, W; Mikolajczak, P; Okulicz-Kozaryn, I, 2013) |
| "The aim of the present study was to investigate the preemptive analgesic effects of intraperitoneally administrated midazolam and diclofenac, before acute and inflammatory induced pain in rat model." | 3.77 | Preemptive analgesic effects of midazolam and diclofenac in rat model. ( Hasani, A; Jakupi, M; Soljakova, M; Ustalar-Ozgen, S, 2011) |
| " Since 2005 to 2007, we evaluated the safety and efficacy of ketamine to control pain induced by diagnostic procedures in pediatric oncology patients." | 3.75 | [Sedation using ketamine for pain procedures in Pediatric Oncology.]. ( Bernard, F; Ricard, C; Tichit, R; Troncin, R, 2009) |
| "Eight right-handed male volunteers underwent fMRI combined with a thermal pain conditioning paradigm and midazolam (30 mug/kg) or saline administration on different occasions, with order randomized across volunteers." | 3.74 | The anxiolytic effects of midazolam during anticipation to pain revealed using fMRI. ( Lujan, BJ; Peskett, GD; Rogers, R; Schweinhardt, P; Tracey, I; Wise, RG, 2007) |
| " The questionnaire retrieved the endoscopists' experience regarding patients' discomfort or pain under sedation with midazolam, their wish for better sedative agents, their preferred sedative regimens, their medical specialty and their professional experience." | 3.74 | Midazolam-pain, but one cannot remember it: a survey among Southern German endoscopists. ( Frimberger, E; Hollweck, R; Schmid, RM; von Delius, S, 2007) |
| "The purpose of this study is to compare the sedation recovery times of children receiving ketamine/midazolam (K/M) versus K/M and initial pain treatment (morphine or meperidine) in pediatric emergency care." | 3.73 | Effects of initial pain treatment on sedation recovery time in pediatric emergency care. ( Losek, JD; Reid, S, 2006) |
| "IV Midazolam and IV Ketamine were used for PSA in pediatric oncology patients undergoing painful procedures." | 3.73 | Safe and efficacious use of procedural sedation and analgesia by non-anesthesiologists in a pediatric hematology-oncology unit. ( Advani, SH; Ambulkar, I; Borker, A; Gopal, R, 2006) |
| "Systemically administered midazolam induced antinociception for inflammatory pain only, while intrathecal administration elicited antinociceptive effects on both acute thermal and inflammatory-induced pain." | 3.73 | Analgesic effects of systemic midazolam: comparison with intrathecal administration. ( Nishiyama, T, 2006) |
| "To determine the proportion of emergency departments in the UK that use modern pharmacological methods of pain and anxiety control in children, such as analgesia with intranasal diamorphine, procedural sedation using ketamine or midazolam, and adrenaline-cocaine gel, TAC or LAT for anaesthetising wounds in children." | 3.73 | Consigning "brutacaine" to history: a survey of pharmacological techniques to facilitate painful procedures in children in emergency departments in the UK. ( Chavada, G; Coats, T; Davies, F; Loryman, B, 2006) |
| "Our results showed that propofol provided good sedation with excellent pain control, a short recovery time and no significant haemodynamic side effects." | 3.72 | Comparison of colonoscopies performed under sedation with propofol or with midazolam or without sedation. ( Bates, M; Gasparović, S; Opacić, M; Petrovecki, M; Rustemović, N, 2003) |
| "In both acute thermal- and inflammatory-induced pain, intrathecally administered midazolam and bupivacaine produced synergistic analgesia with decreased side effects in intrathecally catheterized rats." | 3.72 | Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain. ( Hanaoka, K; Nishiyama, T, 2003) |
| "Spinally-administered midazolam, a benzodiazepine, and clonidine, an alpha2-adrenergic receptor agonist, have significant synergistic effects on thermally-induced acute and formalin-induced inflammatory pain." | 3.71 | The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats. ( Hanaoka, K; Nishiyama, T, 2001) |
| " In 55% of group 2 patients the level of pain during the procedure was significant but bearable, in 35% it was considered unbearable and in 10% sedation with midazolam was necessary." | 3.71 | A single injection of lidocaine as local anesthesia for ultrasound guided needle biopsy of the prostate. ( Benetti, A; Giusti, G; Graziotti, P; Maffezzini, M; Seveso, M; Taverna, G, 2002) |
| "We evaluated the safety and efficacy of midazolam-ketamine association to control pain induced by diagnostic procedures in paediatric oncology patients." | 3.70 | Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study. ( Granry, JC; Le Moine, P; Monrigal, JP; Pellier, I; Rialland, X; Rod, B, 1999) |
| "The purpose of this study was to examine the anaesthetic requirement of intrathecal midazolam in a dose-response fashion in isoflurane-anaesthetized, tracheostomized rats, and to evaluate the apnoeic threshold after each intrathecal midazolam dose." | 3.69 | Intrathecal midazolam reduces isoflurane MAC and increases the apnoeic threshold in rats. ( Forster, A; Jorge-Costa, M; Morel, DR; Pizzolato, GP; Schwieger, IM, 1994) |
| "To determine the clinical usefulness of the long-term intrathecal administration of midazolam and clonidine in patients with refractory neurogenic and musculoskeletal pain." | 3.69 | Long-term intrathecal administration of midazolam and clonidine. ( Borg, PA; Krijnen, HJ, 1996) |
| " A retrospective analysis of 79 ESWL procedures on 73 consecutive unselected patients was done in an attempt to determine the effectiveness of TENS in reducing the amount of intravenous fentanyl citrate and/or midazolam HCl needed to control pain and anxiety during the ESWL procedure." | 3.68 | The use of transcutaneous electrical nerve stimulation during the biliary lithotripsy procedure. ( Baumgartner, BR; Evans, GR; Fraser, NP; Jones, V; Nelson, RC; Peterson, J; Torres, WE, 1992) |
| "Remimazolam is an ultrashort-acting benzodiazepine that is potentially a practical option for procedural sedation in colonoscopy." | 3.11 | Discharge readiness after remimazolam versus propofol for colonoscopy: A randomised, double-blind trial. ( Chen, L; Fu, B; Guan, J; Liu, L; Yao, Y; Zheng, X, 2022) |
| "Patients with renal lithiasis were included and were randomized to Group A (basal analgesia: midazolam (1 mg), fentanyl (0." | 3.11 | Value of Music and Nitrous Oxide for Pain Control during Extracorporeal Shock Wave Lithotripsy (ESWL). ( Alcoba-García, MP; Bueno-Serrano, G; González-Enguita, C; González-López, R; Llanos-Jiménez, L; Mahillo-Fernández, I; Tabares-Jiménez, J, 2022) |
| " The efficacy and safety of the sedations including sedation time intervals, nausea score, vomiting episodes, pain score, adverse effects, and parent's satisfaction were evaluated." | 3.11 | The efficacy and safety of midazolam with fentanyl versus midazolam with ketamine for bedside invasive procedural sedation in pediatric oncology patients: A randomized, double-blinded, crossover trial. ( Lertvivatpong, N; Malaithong, W; Monsereenusorn, C; Photia, A; Rujkijyanont, P; Traivaree, C, 2022) |
| "Pain has long been defined as an unpleasant sensory and emotional experience originating from any region of the body in the presence or absence of tissue injury." | 3.01 | Procedural (Conscious) Sedation and Analgesia in Emergency Setting: How to Choose Agents? ( Akman, C; Ayan, M; Karcioglu, O; Ozbay, S; Ozsoy, O; Suzer, NE, 2023) |
| "Propofol was significantly better than midazolam in inducing amnesia of procedural pain (mean difference 11." | 2.80 | Propofol-alfentanyl versus midazolam-alfentanyl in inducing procedural amnesia of upper gastrointestinal endoscopy in children--blind randomised trial. ( Albrecht, P; Dziechciarz, P; Sienkiewicz, E; Ziółkowski, J, 2015) |
| "Endovascular abdominal aortic aneurysm (AAA) repair was performed with local anaesthesia and intravenous analgesia." | 2.76 | Analgesia and endocrine surgical stress: effect of two analgesia protocols on cortisol and prolactin levels during abdominal aortic aneurysm endovascular repair. ( Baraldi, E; Barbieri, A; Coppi, G; D'Amico, R; Ferrari, A; Genazzani, A; Giuliani, E, 2011) |
| "Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia." | 2.75 | Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010) |
| "In this study recovery profile, postoperative pain scores, incidence of adverse effects, and patient and surgeon satisfaction were compared between paravertebral block (PVB) and fast-track general anesthesia (GA) via laryngeal mask airway (LMA) for outpatient IH." | 2.75 | Comparison of paravertebral block versus fast-track general anesthesia via laryngeal mask airway in outpatient inguinal herniorrhaphy. ( Akcaboy, EY; Akcaboy, ZN; Gogus, N, 2010) |
| "Patients receiving propofol reached full recovery sooner (16." | 2.71 | Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists. ( Chadalawada, V; Hansen, JJ; Liangpunsakul, S; Mendel, AM; Overley, CA; Rex, DK; Strahl, E; Symms, MR; Ulmer, BJ, 2003) |
| "Diazepam and midazolam were equivalent as judged by sedation, recovery time, patient tolerance, and ease of examination." | 2.69 | Midazolam versus diazepam in lipid emulsion as conscious sedation for colonoscopy with or without reversal of sedation with flumazenil. ( Gevers, AM; Hendrickx, A; Macken, E; Rutgeerts, P, 1998) |
| "The reduction in allodynia evoked by light stroking was statistically significant only for alfentanil." | 2.68 | Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects. ( Bennett, GJ; Gracely, RH; Max, MB; Park, KM; Robinovitz, E, 1995) |
| " Midazolam concentrations were also measured and pharmacokinetic parameters determined using a population modelling package." | 2.68 | Haemodynamic responses and population pharmacokinetics of midazolam following administration to ventilated, preterm neonates. ( Charles, BG; Gray, PH; Harte, GJ; Lee, TC; Steer, PA, 1997) |
| "Isoflurane is a useful agent for prolonged sedation of ventilated patients and does not have any adverse effect on the cardiorespiratory system or on hepatic, renal or adrenal function." | 2.67 | Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety. ( Spencer, EM; Willatts, SM, 1992) |
| "Midazolam was found to be the drug of preference for the majority of patients." | 2.67 | Midazolam versus fentanyl as premedication for painful procedures in children with cancer. ( Conner, K; Dickson, N; Luzins, J; McGorray, S; Reilly, K; Sandler, ES; Weyman, C, 1992) |
| "Alfentanil was used as an adjuvant to midazolam for analgesia in thirty outpatients undergoing colonoscopy." | 2.67 | Pain relief for outpatient colonoscopy: a comparison of alfentanil with fentanyl. ( Holloway, AM; Logan, DA, 1990) |
| "Midazolam is a recently introduced benzodiazepine with a half life of 1-4 hours." | 2.66 | A comparison of midazolam and diazepam for sedation during locoregional anesthesia. ( Donadoni, R; Herregods, L; Mortier, E; Rolly, G, 1987) |
| "Intubation of the trachea and mechanical ventilation are ubiquitous painful procedures in the neonatal intensive care unit that are poorly assessed and treated." | 2.49 | Sedation and analgesia to facilitate mechanical ventilation. ( Colby, CE; Nemergut, ME; Yaster, M, 2013) |
| "The most prevalent symptoms were: breathlessness, weakness/lack of energy, drowsiness, anxiety, agitation, confusion/delirium, and pain." | 1.72 | Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom). ( Bajwah, S; Bradshaw, A; Chambers, RL; Dunleavy, L; Fraser, LK; Higginson, IJ; Hocaoglu, MB; Maddocks, M; Murtagh, FEM; Oluyase, AO; Preston, N; Sleeman, KE; Walshe, C, 2022) |
| "Pediatric lacerations are frequently encountered by plastic surgeons in the emergency room." | 1.72 | Effect of sedation using Ketamine for primary closure of pediatric facial laceration. ( Kim, HJ; Kim, JH; Kim, SH; Lee, JH; Shin, SH; Suh, IS; Woo, SS, 2022) |
| "To assess sedation medication dosage differences between patients with and without opioid use disorder at the time of surgical abortion." | 1.62 | Pain medication requirements in patients with opioid use disorder at the time of surgical abortion: An exploratory study. ( Ramanadhan, S; Srikanth, P; White, KO; Woodhams, E, 2021) |
| "Atropine was given in 19/40 intubations." | 1.51 | Premedication practices for tracheal intubation in neonates transported by French medical transport teams: a prospective observational study. ( Ayachi, A; Carbajal, R; Chabernaud, JL; Chouakri, O; Cimerman, P; Courtois, E; Henry-Larzul, V; Kessous, K; Lode, N; Normand, A; Rousseau, J, 2019) |
| " Predictors of poorer neurocognitive function were midazolam dosage >3 mg (P<0." | 1.51 | Comparison of the Effects of Midazolam/Fentanyl, Midazolam/Propofol, and Midazolam/Fentanyl/Propofol on Cognitive Function After Gastrointestinal Endoscopy. ( Riordan, S; Seck, V; Thompson, R; Wong, S, 2019) |
| "Propofol sedations were more often associated with the occurrence of apnea's (20% vs." | 1.46 | Propofol versus midazolam for procedural sedation in the emergency department: A study on efficacy and safety. ( Beije, F; Bens, BWJ; Bosch, MGE; Feenstra, R; Lameijer, H; Pol, A; Sikkema, YT; Ter Avest, E, 2017) |
| "Midazolam was the sedative agent used most commonly (45%), and morphine was the most frequently used analgesic agent (36%)." | 1.42 | Emergency department procedural sedation: the London experience. ( Baker, EC; Elkhodair, SM; Freund, Y; Glasebrook, WR; Harris, TR; Pott, JD, 2015) |
| " We recorded adverse events during the endoscopic procedure and additionally retrieved questionnaires investigating subjective parameters 24 h after the endoscopic procedure." | 1.40 | Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices. ( Beck, S; Friedrich, K; Gotthardt, DN; Heil, FJ; Rex, DK; Scholl, SG; Sieg, A; Stremmel, W, 2014) |
| "Specific premedication prior to endotracheal intubation was assessed." | 1.39 | Premedication for neonatal endotracheal intubation: results from the epidemiology of procedural pain in neonates study. ( Boëlle, PY; Boileau, P; Carbajal, R; Coursol, A; Daoud, P; de Saint Blanquat, L; Decobert, F; Durand, P; Durrmeyer, X; Granier, M; Lapillonne, A; Lenclen, R; Nicloux, M; Renolleau, S; Saizou, C; Shankland, R; Zana-Taieb, E, 2013) |
| " The dosage of propofol recommended in these guidelines is, however, based on one single study." | 1.39 | [Palliative sedation in a man with oral cancer; the Royal Dutch Medical Association guidelines not always sufficient]. ( Broekhoff, FJ; Dompeling, EC; Smelt, WL; Vos-Westerman, JH; Wulffraat, ET, 2013) |
| "Pain was associated with younger age (p < 0." | 1.38 | The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation. ( Jeurnink, SM; Kuipers, E; Siersema, P; Steyerberg, E, 2012) |
| " Demographic data, time in ED, and dosage of each medication given were abstracted." | 1.35 | Inadequate provision of postintubation anxiolysis and analgesia in the ED. ( Bonomo, JB; Butler, AS; Lindsell, CJ; Venkat, A, 2008) |
| "Midazolam was the most frequently prescribed drug." | 1.34 | [Treatment of intolerable sufferings in a hospice unit]. ( Bull, AN; Rosland, JH; Saunes, TK, 2007) |
| "The ease of endotracheal intubation has been recently shown to affect the incidence of laryngeal injury." | 1.33 | Tracheal intubation in routine practice with and without muscular relaxation: an observational study. ( Adnet, F; Ait Kaci, F; Baillard, C; Borron, SW; Cupa, M; Fournier, JL; Larmignat, P; Racine, SX; Samama, CM, 2005) |
| "midazolam were significantly reversed by i." | 1.31 | Effects of midazolam in the spinal nerve ligation model of neuropathic pain in rats. ( Dickenson, AH; Kontinen, VK, 2000) |
| "Midazolam was the most common medication prescribed to achieve sedation." | 1.31 | A multicentre international study of sedation for uncontrolled symptoms in terminally ill patients. ( Bengtson, K; Bercovici, M; deMoissac, D; Fainsinger, RL; Hosking, M; Landman, W; Nunez-Olarte, JM; Waller, A, 2000) |
| "Propofol and midazolam were compared in 40 adult patients in A." | 1.31 | A comparative study of induction and recovery characteristics of propofol and midazolam. ( Dangnan, F; Edomwonyi, NP; Okonofua, BA; Weerasinghe, AS, 2001) |
| "Intraoperative pain is the main topic that requires improvement." | 1.31 | Feasibility of local infiltration anaesthesia for recurrent groin hernia repair. ( Bech, K; Callesen, T; Kehlet, H, 2001) |
| "Midazolam 1 mg was effective in the males (from 45% to 10%) and tended to allay patients' pain feeling in the females (from 40% to 23%)." | 1.29 | [The effects of small dose midazolam in patients to reduce the uncomfortable feeling during epidural block procedure]. ( Kasaba, T, 1994) |
| "The midazolam-treated patients had a numerically lower mean pain score (1." | 1.29 | Midazolam sedation for percutaneous liver biopsy. ( Alexander, JA; Smith, BJ, 1993) |
| "Midazolam was injected at four different concentrations: 0." | 1.29 | Inhibition of morphine-induced tolerance and dependence by a benzodiazepine receptor agonist midazolam in the rat. ( McDonald, JS; Rattan, AK; Sheu, MJ; Sribanditmongkol, P; Tejwani, GA; Zuniga, J, 1993) |
| "Shivering and hiccoughing were noted in two and four cases, respectively." | 1.29 | Methohexital infusion technique for conscious sedation. ( Buckley, M; Johns, FR; Ziccardi, VB, 1996) |
| "Midazolam was shown to have no effect on the acquisition of the enduring naloxone-reversible analgesia." | 1.29 | Midazolam impairs the acquisition of conditioned analgesia if rats are tested with an acute but not a chronic noxious stimulus. ( Harris, JA; Westbrook, RF, 1996) |
| "Both midazolam and morphine were effective in reducing the nociceptive response of the second phase of this biphasic pain test." | 1.28 | Intrathecal midazolam versus intrathecal morphine in orofacial nociception: an experimental study in rats. ( Aigouy, L; Fondras, JC; Pajot, J; Schoeffler, P; Woda, A, 1992) |
| "Midazolam 2." | 1.28 | [The effects of pentazocine, diazepam and midazolam in patients to reduce the uncomfortable feeling during epidural block procedure]. ( Kasaba, T, 1992) |
| " Flumazenil (Ro 15-1788) administration caused a parallel shift to the right of the dose-response curve for midazolam spinal analgesia." | 1.28 | On the mechanism by which midazolam causes spinally mediated analgesia. ( Edwards, M; Gent, JP; Goodchild, CS; Serrao, JM, 1990) |
| "Children with leukemia have to undergo many times painful procedures like bone-marrow aspiration and lumbar puncture." | 1.27 | [Sedation and analgesia in interventions]. ( de Waal, FC; Huisman, J; Veerman, AJ, 1988) |
Research
Studies (323)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (3.41) | 18.7374 |
| 1990's | 83 (25.70) | 18.2507 |
| 2000's | 99 (30.65) | 29.6817 |
| 2010's | 92 (28.48) | 24.3611 |
| 2020's | 38 (11.76) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Huang, SM | 1 |
| Hsu, H | 1 |
| Hii, IH | 1 |
| Chang, CH | 1 |
| Sirohiya, P | 1 |
| Kumar, V | 1 |
| Mittal, S | 1 |
| Gupta, N | 1 |
| Garg, R | 1 |
| Bharati, SJ | 1 |
| Mishra, S | 1 |
| Hadda, V | 1 |
| Mohan, A | 1 |
| Sagiraju, HKR | 1 |
| Bhatnagar, S | 1 |
| Madan, K | 1 |
| Nicholas, TG | 1 |
| Husbands, EL | 1 |
| Garcia, ACM | 1 |
| Isidoro, GM | 1 |
| Paiva, EMDC | 1 |
| Silva, AE | 1 |
| Costa, ICP | 1 |
| Bornemann-Cimenti, H | 1 |
| Wallen, TE | 1 |
| Elson, NC | 1 |
| Singer, KE | 1 |
| Hayes, HV | 1 |
| Salvator, A | 1 |
| Droege, CA | 1 |
| Nomellini, V | 1 |
| Pritts, TA | 1 |
| Goodman, MD | 1 |
| Katsurada, M | 1 |
| Tachihara, M | 1 |
| Katsurada, N | 1 |
| Takata, N | 1 |
| Sato, H | 1 |
| Mimura, C | 1 |
| Yoshioka, J | 1 |
| Furukawa, K | 1 |
| Yumura, M | 1 |
| Otoshi, T | 1 |
| Yasuda, Y | 1 |
| Kiriu, T | 1 |
| Hazama, D | 1 |
| Nagano, T | 1 |
| Yamamoto, M | 1 |
| Nishimura, Y | 1 |
| Kobayashi, K | 1 |
| Higginson, IJ | 1 |
| Hocaoglu, MB | 1 |
| Fraser, LK | 1 |
| Maddocks, M | 1 |
| Sleeman, KE | 1 |
| Oluyase, AO | 1 |
| Chambers, RL | 1 |
| Preston, N | 1 |
| Dunleavy, L | 1 |
| Bradshaw, A | 1 |
| Bajwah, S | 1 |
| Murtagh, FEM | 1 |
| Walshe, C | 1 |
| Yao, Y | 2 |
| Guan, J | 1 |
| Liu, L | 1 |
| Fu, B | 1 |
| Chen, L | 1 |
| Zheng, X | 1 |
| Chin, J | 1 |
| McGrath, M | 1 |
| Lokken, E | 1 |
| Upegui, CD | 1 |
| Prager, S | 1 |
| Micks, E | 1 |
| Lee, JH | 2 |
| Woo, SS | 1 |
| Shin, SH | 1 |
| Kim, HJ | 1 |
| Kim, JH | 2 |
| Kim, SH | 2 |
| Suh, IS | 1 |
| Azarfar, A | 1 |
| Ravanshad, Y | 1 |
| Golsorkhi, M | 1 |
| Zahiri, E | 1 |
| Gharavi Fard, M | 1 |
| Akhondi, M | 1 |
| Ghodsi, A | 1 |
| Ravanshad, S | 1 |
| Lai, HC | 1 |
| Chen, CL | 1 |
| Huang, YH | 1 |
| Wu, KL | 1 |
| Huang, RC | 1 |
| Lin, BF | 1 |
| Chan, SM | 1 |
| Wu, ZF | 1 |
| Rodrigues Tavares, LR | 1 |
| Baptista-de-Souza, D | 1 |
| Canto-de-Souza, L | 1 |
| Planeta, CDS | 1 |
| Guimarães, FS | 1 |
| Nunes-de-Souza, RL | 3 |
| Canto-de-Souza, A | 2 |
| Bueno-Serrano, G | 1 |
| Alcoba-García, MP | 1 |
| Tabares-Jiménez, J | 1 |
| González-López, R | 1 |
| Llanos-Jiménez, L | 1 |
| Mahillo-Fernández, I | 1 |
| González-Enguita, C | 1 |
| Monsereenusorn, C | 1 |
| Malaithong, W | 1 |
| Lertvivatpong, N | 1 |
| Photia, A | 1 |
| Rujkijyanont, P | 1 |
| Traivaree, C | 1 |
| Brant, AR | 1 |
| Reeves, MF | 1 |
| Ye, PP | 1 |
| Scott, RK | 1 |
| Floyd, S | 1 |
| Tefera, E | 1 |
| Lotke, PS | 1 |
| Saberi, N | 3 |
| Hayrabedian, A | 3 |
| Mazdak, H | 3 |
| Hassannejad, R | 3 |
| Zargham, M | 3 |
| Mohammadi Sichani, M | 3 |
| Mirzaei, M | 3 |
| Parhar, D | 2 |
| Baum, RA | 2 |
| Spouge, R | 2 |
| Yan, T | 2 |
| Ho, S | 2 |
| Hadjivassiliou, A | 2 |
| Machan, L | 2 |
| Legiehn, G | 2 |
| Klass, D | 2 |
| Dhatt, R | 2 |
| Boucher, LM | 2 |
| Liu, DM | 2 |
| Ramin, S | 2 |
| Bringuier, S | 2 |
| Martinez, O | 2 |
| Sadek, M | 2 |
| Manzanera, J | 2 |
| Deras, P | 2 |
| Choquet, O | 2 |
| Charbit, J | 2 |
| Capdevila, X | 2 |
| Raouf, MM | 1 |
| Abo-Elhessein, AK | 1 |
| Hasanein, M | 1 |
| Abskharon, JE | 1 |
| Hassan, SS | 1 |
| Talaat, EA | 1 |
| Elawamy, AR | 1 |
| Kamel, EZ | 1 |
| Liu, J | 1 |
| Ye, YJ | 1 |
| Liu, SM | 1 |
| Liu, S | 1 |
| Wang, J | 2 |
| Lu, C | 1 |
| Liu, X | 1 |
| Zhang, G | 1 |
| Zhang, J | 1 |
| Gao, M | 1 |
| Liu, D | 2 |
| Zhang, X | 1 |
| Liu, Y | 1 |
| Wang, X | 1 |
| Zhang, S | 1 |
| Wang, C | 1 |
| Huang, Y | 1 |
| Wu, H | 1 |
| Zhao, G | 1 |
| Wang, T | 1 |
| Pace, L | 1 |
| Howard, M | 1 |
| Makar, E | 1 |
| Lee, J | 1 |
| Vogt, KM | 2 |
| Ibinson, JW | 2 |
| Burlew, AC | 1 |
| Smith, CT | 2 |
| Aizenstein, HJ | 2 |
| Fiez, JA | 2 |
| Schubert, AK | 1 |
| Seneviratne, V | 1 |
| Stolz, J | 1 |
| Wiesmann, T | 1 |
| Wulf, H | 1 |
| Eberhart, L | 1 |
| Dinges, HC | 1 |
| Elattar, MM | 1 |
| NBiomy, R | 1 |
| Haseeb, WA | 1 |
| Salama, MK | 1 |
| Bromfalk, Å | 1 |
| Hultin, M | 1 |
| Myrberg, T | 1 |
| Engström, Å | 1 |
| Walldén, J | 1 |
| Stróżyk, A | 1 |
| Paraskevas, T | 1 |
| Romantsik, O | 1 |
| Calevo, MG | 1 |
| Banzi, R | 1 |
| Ley, D | 1 |
| Bruschettini, M | 1 |
| Ayan, M | 1 |
| Ozsoy, O | 1 |
| Ozbay, S | 1 |
| Akman, C | 1 |
| Suzer, NE | 1 |
| Karcioglu, O | 1 |
| Michel, J | 1 |
| Hofbeck, M | 1 |
| Peper, AK | 1 |
| Kumpf, M | 1 |
| Neunhoeffer, F | 1 |
| Khalil, W | 1 |
| Raslan, N | 1 |
| Donato, J | 1 |
| Rao, K | 1 |
| Lewis, T | 1 |
| Carbajal, R | 2 |
| Lode, N | 1 |
| Ayachi, A | 1 |
| Chouakri, O | 1 |
| Henry-Larzul, V | 1 |
| Kessous, K | 1 |
| Normand, A | 1 |
| Courtois, E | 1 |
| Rousseau, J | 1 |
| Cimerman, P | 1 |
| Chabernaud, JL | 1 |
| Patel, C | 1 |
| Kleinig, P | 1 |
| Bakker, M | 1 |
| Tait, P | 1 |
| Cinotti, R | 1 |
| Besnard, N | 1 |
| Desmedt, L | 1 |
| Floch, RL | 1 |
| Perrot, P | 1 |
| Bekara, F | 1 |
| Klouche, K | 1 |
| Larcher, R | 1 |
| Mahé, PJ | 1 |
| Frasca, D | 1 |
| Asehnoune, K | 1 |
| Jung, B | 1 |
| Roquilly, A | 1 |
| Poulton, T | 1 |
| Hogston, SP | 1 |
| Bolton, WS | 1 |
| Burke, JR | 1 |
| Jayne, DG | 1 |
| Abushanab, D | 1 |
| Abounahia, FF | 1 |
| Alsoukhni, O | 1 |
| Abdelaal, M | 1 |
| Al-Badriyeh, D | 1 |
| Citro, AT | 1 |
| Norton, CM | 1 |
| Karim, HT | 1 |
| Popov, V | 1 |
| Mahajan, A | 1 |
| Reder, LM | 1 |
| Ramanadhan, S | 1 |
| Woodhams, E | 1 |
| Srikanth, P | 1 |
| White, KO | 1 |
| Prosenz, J | 1 |
| Gustorff, B | 1 |
| Peng, ZY | 1 |
| Zhou, WH | 1 |
| Hu, B | 1 |
| Rao, X | 1 |
| Li, JG | 1 |
| Kang, H | 2 |
| Nakae, A | 1 |
| Ito, H | 1 |
| Vitayaburananont, P | 1 |
| Minamoto, T | 1 |
| Ikeda, T | 1 |
| Osaka, M | 1 |
| Mashimo, T | 1 |
| Fujino, Y | 1 |
| Hagihira, S | 2 |
| Gargiulo, M | 1 |
| Cortese, A | 1 |
| Pantaleo, G | 1 |
| Parascandalo, S | 1 |
| Amato, M | 1 |
| Li, QD | 1 |
| Wan, XY | 1 |
| Zhang, YL | 1 |
| Li, SW | 1 |
| Han, LL | 1 |
| Li, WW | 1 |
| Shi, HY | 1 |
| Nunes, SL | 1 |
| Forsberg, S | 1 |
| Blomqvist, H | 1 |
| Berggren, L | 1 |
| Sörberg, M | 1 |
| Sarapohja, T | 2 |
| Wickerts, CJ | 1 |
| Tsze, DS | 2 |
| Ieni, M | 1 |
| Flores-Sanchez, PL | 1 |
| Shen, ST | 1 |
| Bregstein, JS | 1 |
| O'Connell, NC | 1 |
| Dayan, PS | 1 |
| Nasr, VG | 1 |
| DiNardo, JA | 1 |
| Thaxton, L | 1 |
| Pitotti, J | 1 |
| Espey, E | 1 |
| Teal, S | 1 |
| Sheeder, J | 1 |
| Singh, RH | 1 |
| Norii, T | 1 |
| Homma, Y | 1 |
| Shimizu, H | 1 |
| Takase, H | 1 |
| Nagata, S | 1 |
| Shimosato, A | 1 |
| Crandall, C | 1 |
| Ingravallo, F | 1 |
| de Nooijer, K | 1 |
| Pucci, V | 1 |
| Casini, C | 1 |
| Miccinesi, G | 1 |
| Rietjens, JAC | 1 |
| Morino, P | 1 |
| Oguntoye, CO | 1 |
| Oyewande, OA | 1 |
| Afolabi, OO | 1 |
| Thompson, R | 1 |
| Seck, V | 1 |
| Riordan, S | 1 |
| Wong, S | 1 |
| Puijk, RS | 1 |
| Ziedses des Plantes, V | 1 |
| Nieuwenhuizen, S | 1 |
| Ruarus, AH | 1 |
| Vroomen, LGPH | 1 |
| de Jong, MC | 1 |
| Geboers, B | 1 |
| Hoedemaker-Boon, CJ | 1 |
| Thöne-Passchier, DH | 1 |
| Gerçek, CC | 1 |
| de Vries, JJJ | 1 |
| van den Tol, PMP | 1 |
| Scheffer, HJ | 1 |
| Meijerink, MR | 1 |
| Shavit, I | 2 |
| Feraru, L | 1 |
| Miron, D | 1 |
| Weiser, G | 1 |
| Durrmeyer, X | 1 |
| Daoud, P | 1 |
| Decobert, F | 1 |
| Boileau, P | 1 |
| Renolleau, S | 1 |
| Zana-Taieb, E | 1 |
| Saizou, C | 1 |
| Lapillonne, A | 1 |
| Granier, M | 1 |
| Durand, P | 1 |
| Lenclen, R | 1 |
| Coursol, A | 1 |
| Nicloux, M | 1 |
| de Saint Blanquat, L | 1 |
| Shankland, R | 1 |
| Boëlle, PY | 1 |
| Deftereos, S | 1 |
| Giannopoulos, G | 1 |
| Raisakis, K | 1 |
| Hahalis, G | 1 |
| Kaoukis, A | 1 |
| Kossyvakis, C | 1 |
| Avramides, D | 1 |
| Pappas, L | 1 |
| Panagopoulou, V | 1 |
| Pyrgakis, V | 1 |
| Alexopoulos, D | 1 |
| Stefanadis, C | 1 |
| Cleman, MW | 1 |
| Smelt, WL | 1 |
| Wulffraat, ET | 1 |
| Broekhoff, FJ | 1 |
| Dompeling, EC | 1 |
| Vos-Westerman, JH | 1 |
| Porhomayon, J | 1 |
| Nader, ND | 1 |
| El-Solh, AA | 1 |
| Hite, M | 1 |
| Scott, J | 1 |
| Silinskie, K | 1 |
| Barkan, S | 1 |
| Breitbart, R | 1 |
| Brenner-Zada, G | 1 |
| Feldon, M | 1 |
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| Xhaja, X | 1 |
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| Avino, D | 1 |
| Zhang, WH | 1 |
| De Villé, A | 1 |
| Johansson, AB | 1 |
| Sieg, A | 2 |
| Beck, S | 1 |
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| Heil, FJ | 1 |
| Gotthardt, DN | 1 |
| Stremmel, W | 1 |
| Rex, DK | 3 |
| Friedrich, K | 1 |
| Lier, MC | 1 |
| Douwenga, WM | 1 |
| Yilmaz, F | 1 |
| Schats, R | 1 |
| Hompes, PG | 1 |
| Boer, C | 1 |
| Mijatovic, V | 1 |
| Chen, ZY | 1 |
| Wang, H | 1 |
| Xu, W | 1 |
| Xu, H | 1 |
| Fu, X | 1 |
| Yu, J | 1 |
| Zhang, Y | 1 |
| Lu, Y | 1 |
| Dong, C | 2 |
| Constantine, E | 1 |
| Machan, JT | 1 |
| Eberson, CP | 1 |
| Linakis, JG | 1 |
| Steele, DW | 1 |
| Derakhshanfar, H | 1 |
| Kordi, MM | 1 |
| Amini, A | 1 |
| Shojahee, M | 1 |
| Milési, C | 1 |
| Doğanca, T | 1 |
| Savsin, A | 1 |
| Erdoğan, S | 1 |
| Altindas, F | 1 |
| Özdemir, F | 1 |
| Ekici, B | 1 |
| Öbek, C | 1 |
| Elkhodair, SM | 1 |
| Baker, EC | 1 |
| Glasebrook, WR | 1 |
| Pott, JD | 1 |
| Freund, Y | 1 |
| Harris, TR | 1 |
| Hong, MJ | 1 |
| Sung, IK | 1 |
| Lee, SP | 1 |
| Cheon, BK | 1 |
| Kim, TY | 1 |
| Leppert, W | 2 |
| Okulicz-Kozaryn, I | 2 |
| Kaminska, E | 2 |
| Szulc, M | 1 |
| Mikolajczak, P | 2 |
| Park, SY | 1 |
| Kim, MG | 1 |
| Choi, H | 1 |
| Song, D | 1 |
| Cho, SW | 1 |
| Song, YS | 2 |
| Caldwell, CD | 1 |
| Watterberg, KL | 1 |
| Azoulay, D | 1 |
| Shahal-Gassner, R | 1 |
| Yehezkel, M | 1 |
| Eliyahu, E | 1 |
| Weigert, N | 1 |
| Ein-Mor, E | 1 |
| Jacobs, JM | 1 |
| Ralvenius, WT | 1 |
| Benke, D | 1 |
| Acuña, MA | 1 |
| Rudolph, U | 1 |
| Zeilhofer, HU | 1 |
| Gelen, SA | 1 |
| Sarper, N | 1 |
| Demirsoy, U | 1 |
| Zengin, E | 1 |
| Çakmak, E | 1 |
| Wolkers, CP | 1 |
| Barbosa Junior, A | 1 |
| Menescal-de-Oliveira, L | 1 |
| Hoffmann, A | 1 |
| Belmont, AP | 1 |
| Nossair, F | 1 |
| Brambilla, D | 1 |
| Friedman, M | 1 |
| Boswinkel, J | 1 |
| Bradford, AB | 1 |
| Kwiatkowski, JL | 1 |
| Sienkiewicz, E | 1 |
| Albrecht, P | 1 |
| Ziółkowski, J | 1 |
| Dziechciarz, P | 1 |
| Li, S | 1 |
| Yang, Y | 1 |
| Yu, C | 1 |
| Wu, Y | 1 |
| Qian, L | 1 |
| Cheung, CW | 1 |
| Becerra, L | 1 |
| Aasted, CM | 1 |
| Boas, DA | 1 |
| George, E | 1 |
| Yücel, MA | 1 |
| Kussman, BD | 1 |
| Kelsey, P | 1 |
| Borsook, D | 1 |
| Yakoob, MY | 1 |
| Shamim, MS | 1 |
| Manning, CT | 1 |
| Buinewicz, JD | 1 |
| Sewatsky, TP | 1 |
| Zgonis, E | 1 |
| Gutierrez, K | 1 |
| O'Keefe, MF | 1 |
| Freeman, K | 1 |
| Song, R | 1 |
| Li, J | 1 |
| Yang, J | 1 |
| Lyu, J | 1 |
| An, Y | 1 |
| Feng, Y | 1 |
| Liou, JY | 1 |
| Ting, CK | 1 |
| Mandell, MS | 1 |
| Chang, KY | 1 |
| Teng, WN | 1 |
| Huang, YY | 1 |
| Tsou, MY | 1 |
| Afzalimoghaddam, M | 1 |
| Edalatifard, M | 1 |
| Nejati, A | 1 |
| Momeni, M | 1 |
| Isavi, N | 1 |
| Karimialavijeh, E | 1 |
| Lameijer, H | 1 |
| Sikkema, YT | 1 |
| Pol, A | 1 |
| Bosch, MGE | 1 |
| Beije, F | 1 |
| Feenstra, R | 1 |
| Bens, BWJ | 1 |
| Ter Avest, E | 1 |
| Han, SJ | 1 |
| Lee, TH | 1 |
| Park, SH | 1 |
| Cho, YS | 1 |
| Lee, YN | 1 |
| Jung, Y | 1 |
| Choi, HJ | 1 |
| Chung, IK | 1 |
| Cha, SW | 1 |
| Moon, JH | 1 |
| Cho, YD | 1 |
| Kim, SJ | 1 |
| Koyama, S | 1 |
| Ohashi, N | 1 |
| Kurita, S | 1 |
| Nakatani, K | 1 |
| Nagata, N | 1 |
| Toyoda, Y | 1 |
| Dewitt, J | 1 |
| McGreevy, K | 1 |
| Sherman, S | 1 |
| Imperiale, TF | 2 |
| Nagel, K | 1 |
| Willan, AR | 1 |
| Lappan, J | 1 |
| Korz, L | 1 |
| Buckley, N | 1 |
| Barr, RD | 1 |
| Greenhalgh, C | 1 |
| MacPherson, RD | 1 |
| Woods, D | 1 |
| Penfold, J | 1 |
| Chakupurakal, G | 1 |
| Delgado, J | 1 |
| Nikolousis, E | 1 |
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| Serrao, JM | 2 |
| Gent, JP | 2 |
| Sandler, E | 1 |
| Shelly, MP | 1 |
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| Park, GR | 1 |
| Clavier, N | 1 |
| Lombard, MC | 1 |
| Besson, JM | 1 |
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| Fairclough, D | 1 |
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| Mirro, J | 1 |
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| Gilvarry, JM | 1 |
| Craig, M | 1 |
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| Edwards, M | 1 |
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| Kyff, JV | 1 |
| Barclay, JK | 1 |
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| Skowronski, GA | 1 |
| Holloway, AM | 1 |
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| Stewens, J | 1 |
| Tegtmeyer, FK | 1 |
Clinical Trials (71)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketamine Versus Fentanyl for Surgical Abortions: A Randomized Controlled Noninferiority Trial[NCT04871425] | Phase 4 | 110 participants (Actual) | Interventional | 2021-04-27 | Completed | ||
| Comparison of Two Dosage of Remifentanil Infusion Combined With Propofol-based Total Intravenous Anesthesia in Percutaneous Vertebroplasty[NCT05876039] | Phase 4 | 80 participants (Anticipated) | Interventional | 2023-05-31 | Not yet recruiting | ||
| Gabapentin as an Adjunct for Pain Management During Dilation and Evacuation: A Double-blind Randomized Controlled Trial[NCT03635905] | Phase 4 | 130 participants (Actual) | Interventional | 2017-05-26 | Completed | ||
| Organ Protective Effect of Histamine H1 Receptor Antagonist In Patients With Severe Burns: A Clinical Study[NCT06126991] | Phase 1/Phase 2 | 32 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting | ||
| Epidémiologie Des Gestes Douloureux ou Stressants Chez Les Nouveau-nés Pris en Charge Dans Les unités de réanimation néonatale et pédiatrique et Par Les équipes de SMUR de la région d'Ile de France[NCT01346813] | 1,000 participants (Anticipated) | Observational | 2011-05-31 | Completed | |||
| A Survey of Management of Analgesia, Sedation and Delirium in ICU Patients in China[NCT04217915] | 800 participants (Anticipated) | Observational | 2021-07-12 | Recruiting | |||
| Non-interventional Comparison of Sedatives on Weaning From Mechanical Ventilation in Intensive Care Patients[NCT01707680] | 155 participants (Actual) | Observational | 2012-06-01 | Terminated (stopped due to Halted due to slow recruitment) | |||
| Nitrous Oxide Versus Intravenous Sedation for Anesthesia[NCT02755090] | 39 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| Buccal Midazolam Versus Nasal or Oral Midazolam Sedation for Minor Invasive Procedures in Children: A Prospective Randomized Control Study[NCT02408302] | Phase 4 | 90 participants (Anticipated) | Interventional | 2015-04-30 | Not yet recruiting | ||
| Respiratory Effect of the LISA (Less Invasive Surfactant Administration) Method With Sedation by Propofol Versus Absence of Sedation: Double-blind Comparative Randomized Clinical Trial.[NCT04016246] | Phase 3 | 542 participants (Anticipated) | Interventional | 2019-10-07 | Recruiting | ||
| A Randomized, Clinical Trial of Oral Midazolam Plus Placebo Versus Oral Midazolam Plus Oral Ketamine for Sedation During Laceration Repair[NCT01470157] | Phase 4 | 60 participants (Anticipated) | Interventional | 2011-07-31 | Recruiting | ||
| Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis (AKTSS)[NCT03296345] | Phase 2 | 62 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| Ketamine Infusion for Acute Sickle Cell crisiS in the Emergency Department[NCT02417298] | 12 participants (Actual) | Interventional | 2015-11-30 | Terminated (stopped due to Feasibility) | |||
| Same Day Bidirectional Endoscopies - Does the Sequence of Procedures or Choice of Insufflator Matter?[NCT02635217] | 200 participants (Actual) | Interventional | 2016-01-31 | Completed | |||
| Randomized Controlled Trial of Transcutaneous Electrical Nerve Stimulation for Pain Relief During Transvaginal Oocyte Retrieval Using Conscious Sedation[NCT03472430] | 160 participants (Actual) | Interventional | 2018-05-04 | Completed | |||
| Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial[NCT03453359] | 180 participants (Actual) | Interventional | 2018-01-28 | Completed | |||
| Effectiveness of the Distraction Methods on Pain, Anxiety and Satisfaction During Cystoscopy[NCT02764294] | 120 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| Demonstration of OTC Naproxen Sodium's (Aleve's) Anti-inflammatory Action in Dental Implant Surgery Patients[NCT04694300] | Phase 4 | 32 participants (Actual) | Interventional | 2021-02-07 | Completed | ||
| Triple Drug Response Surface Modeling for Patients Receiving Airway Managements[NCT03813875] | 100 participants (Actual) | Observational | 2019-06-12 | Completed | |||
| To Record and Analyze the Physiological Data From Anesthetic Monitoring Instruments Regarding Cardiovascular, Neurological System, and Surgical Stress for Patients Undergoing Laparoscopic Cholecystectomy in a Stepwise Approach.[NCT03691103] | 40 participants (Anticipated) | Observational | 2018-09-30 | Not yet recruiting | |||
| The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia[NCT05525351] | 60 participants (Anticipated) | Observational | 2022-10-31 | Not yet recruiting | |||
| Safety and Efficacy Evaluation of Remimazolam for Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy[NCT05437497] | 264 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | |||
| Analgesic Effect of Ketamine in Patients Undergoing Hysteroscopic Endometrial Thermal Ablation Surgery[NCT01106846] | 22 participants (Actual) | Interventional | 2010-03-31 | Terminated (stopped due to Resources not available to complete.) | |||
| A pRospective, Case-controlled Evaluation of oLIceridine for Moderate or sEVEre Pain in Patients With Acute Burn Injuries. (RELIEVE)[NCT05465226] | Phase 4 | 31 participants (Actual) | Interventional | 2023-04-01 | Completed | ||
| Comparing Pain Relief in Early Labor: Nitrous Oxide Versus Butorphonol Study[NCT01636999] | 0 participants (Actual) | Interventional | 2012-09-30 | Withdrawn | |||
| A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102] | Phase 4 | 105 participants (Actual) | Interventional | 2016-02-29 | Terminated | ||
| The Effect of Single-dose Propofol Injection on Pain and Quality of Life in Chronic Daily Headache: a Randomized Double-blind Controlled Trial[NCT00228267] | Phase 2 | 28 participants (Anticipated) | Interventional | 2004-09-30 | Completed | ||
| [NCT02039453] | 160 participants (Anticipated) | Interventional | 2013-09-30 | Recruiting | |||
| Comparing Time to Readiness for Discharge After Colonoscopy: Propofol and Dexmedetomidine vs Propofol Only Sedation[NCT03139279] | Phase 4 | 122 participants (Actual) | Interventional | 2017-05-05 | Completed | ||
| Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP[NCT01404689] | Phase 4 | 110 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| Dexmedetomidine Compared to Midazolam for Symptom Control in Advanced Cancer Patients: A Pilot Randomized Controlled Trial (RCT)[NCT01687751] | Phase 2 | 0 participants (Actual) | Interventional | 2012-11-30 | Withdrawn (stopped due to Study design determined to be not likely feasible) | ||
| Randomized Controlled Trial Comparing the Impact of Water Assisted Colonoscopy vs Air Insufflation on Resident Training[NCT04987645] | 140 participants (Anticipated) | Interventional | 2022-06-22 | Enrolling by invitation | |||
| Clinical Evaluation of Water Immersion Colonoscopy Insertion Technique[NCT00671177] | 229 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| Water Colonoscopy Versus Air Colonoscopy for Unsedated Patients With Prior Abdominal or Pelvic Surgery: a Prospective Randomized, Controlled Trial[NCT01485133] | 110 participants (Actual) | Observational | 2011-11-30 | Completed | |||
| A Randomized, Controlled Trial Comparing Air Insufflation, Water Immersion and Water Exchange During on Demand Sedation Colonoscopy in CRC Screening Patients[NCT01780818] | 288 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| A Randomized, Controlled Trial Comparing Air Insufflation, Water Immersion and Water Exchange During on Demand Sedation Colonoscopy in Diagnostic Patients[NCT01781650] | 288 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Clinical Randomized Study of Sublingual Midazolam in Association With Morphine by Oral Route in Arm Fracture in Children at the Emergency Children Care[NCT00416039] | Phase 3 | 60 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
| Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure[NCT02684019] | Phase 3 | 60 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| Music Therapy in Procedural Sedation in the Emergency Department[NCT02676206] | 60 participants (Actual) | Interventional | 2016-02-29 | Completed | |||
| Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518] | 250 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | |||
| Efficacy and Safety of Dexmedetomidine Combined With Butorphanol Tartrate for Postoperative Analgesia and Breastfeeding in Cesarean Section[NCT03065530] | Phase 4 | 120 participants (Actual) | Interventional | 2017-02-07 | Completed | ||
| A Prospective, Multi-centre, Randomised, Double-blind Comparison of Intravenous Dexmedetomidine With Midazolam for Continuous Sedation of Ventilated Patients in Intensive Care Unit[NCT00481312] | Phase 3 | 501 participants (Actual) | Interventional | 2007-06-30 | Completed | ||
| Low-dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Patients in Intensive Care Unit: a Multicenter, Randomised, Double-blinded, Placebo-controlled Trial[NCT03172897] | Phase 4 | 260 participants (Anticipated) | Interventional | 2017-08-20 | Suspended (stopped due to The trial was stopped because of difficulty in recruiting patients (another trial had similar inclusion/exclusion criteria). No patients was recruited in this trial.) | ||
| Comparative Study on Development of Paradoxical Excitement Response During Sedation Using Dexmedetomidine or Propofol in Hazardous Alcohol Drinkers[NCT02197403] | Phase 4 | 110 participants (Anticipated) | Interventional | 2013-12-31 | Recruiting | ||
| A Prospective, Multi-centre, Randomised, Double-blind Comparison of Intravenous Dexmedetomidine With Propofol for Continuous Sedation of Ventilated Patients in Intensive Care Unit[NCT00479661] | Phase 3 | 500 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
| PRO-DEFENSE: Propofol Versus Dexmedetomidine for Sedation in Mechanically Ventilated Patients With Sepsis[NCT02203019] | Phase 4 | 36 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| Pain, Agitation and Delirium Protocol in Ventilated Patients in the Duke CICU[NCT02903407] | Phase 4 | 7 participants (Actual) | Interventional | 2017-09-01 | Terminated (stopped due to All enrolled participants completed the study protocol but the study was terminated prior to the goal number of participants due to low recruitment) | ||
| Comparing Warm Versus Cool Temperature Water During Colonoscopy[NCT01322724] | 175 participants (Actual) | Interventional | 2011-06-30 | Completed | |||
| Comparison of Two Different Distraction Methods Affecting the Level of Pain and Anxiety During Extracorporeal Shock Wave Lithotripsy[NCT02725281] | 120 participants (Actual) | Interventional | 2014-04-30 | Completed | |||
| A Randomized Controlled Trial to Evaluate the Effects of Music Therapy on Breastfeeding Rates Among Mothers of Premature Newborns[NCT00930761] | 101 participants (Actual) | Interventional | 2004-03-31 | Completed | |||
| Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP)[NCT02027311] | Phase 4 | 63 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Comparative Study Between Intravenous Nalbuphine Versus Intravenous Dexmedetomidine for Conscious Sedation in Patients Undergoing Colonoscopy[NCT05689242] | Phase 4 | 66 participants (Anticipated) | Interventional | 2023-03-31 | Not yet recruiting | ||
| Midazolam as an Adjuvant to Bupivacaine in Quadratus Lumborum Block After Caesarean Section; Does it Offer Better Pain Control? a Randomized Double Blind Clinical Trial[NCT05261672] | 60 participants (Anticipated) | Interventional | 2022-03-15 | Recruiting | |||
| Efficacy of Alfentanyl Versus Sufentanyl in Children for Pain During Treatment by Tracheal Suction in an Intensive Care Unit.[NCT01235637] | Phase 3 | 40 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| Systemic Absorption of Lidocaine After Ultrasound Guided Hematoma Block for Reduction of Different Types of Pediatric Distal Radius Fractures[NCT04359017] | Phase 4 | 0 participants (Actual) | Interventional | 2020-11-01 | Withdrawn (stopped due to Sponsoring staff have left institution) | ||
| Patient Input Monitoring of Pain in the Emergency Room: Novel Electronic Log (PIMPERNEL). A Randomised Controlled Trial of an Electronic Pain Score Display in Adults in the Emergency Department[NCT03881982] | 105 participants (Actual) | Interventional | 2017-08-03 | Completed | |||
| A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651] | Phase 1 | 20 participants (Actual) | Interventional | 2013-02-28 | Completed | ||
| Comparison of Three Different Pain and Anxiety Reducing Methods in Adult Patients Undergoing Bone Marrow Puncture[NCT00188227] | Phase 4 | 748 participants | Interventional | 2001-09-30 | Completed | ||
| Contribution of Hypnosis in Guided Hepatic Biopsy[NCT05413174] | 70 participants (Actual) | Interventional | 2022-09-29 | Completed | |||
| Nebulized Lidocaine and Intranasal Midazolam for Reducing Pain/Anxiety of Nasogastric Tube Insertion in Children: A Randomized Clinical Trial[NCT04571879] | Phase 3 | 48 participants (Anticipated) | Interventional | 2021-08-25 | Recruiting | ||
| A Randomised Control Trial to Determine Whether Intervention Based on a Microstream Capnography-based Ventilation Monitoring System Will Decrease Hypoxaemaia During Intravenous Sedation With Midazolam.[NCT01949012] | 190 participants (Actual) | Interventional | 2013-10-31 | Completed | |||
| Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions[NCT00596050] | Phase 4 | 50 participants (Actual) | Interventional | 2006-08-31 | Completed | ||
| Ketofol Versus Fentofol for Procedural Sedation of Children 3 to 17 Years Old: a Double-Blind Randomized Controlled Trial[NCT02079090] | Phase 3 | 30 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| Prospective RCT of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy[NCT03160859] | 280 participants (Actual) | Interventional | 2018-06-08 | Completed | |||
| Double-blind, Randomized, Placebo-controlled Study on the Effect of Multimodal Analgesia on Pain With Insertion of Levonorgestrel-releasing Intrauterine System[NCT02799641] | 61 participants (Actual) | Interventional | 2016-07-31 | Completed | |||
| iPad as a Distraction Tool During Facial Laceration Repair[NCT02217436] | 80 participants (Actual) | Interventional | 2014-04-30 | Completed | |||
| Does Endoscope Position Detecting Unit Facilitate Caecal Intubation? A Randomized Controlled Trial[NCT01434199] | Phase 3 | 870 participants (Anticipated) | Interventional | 2011-07-31 | Recruiting | ||
| ScopeGuide-assisted Colonoscopy Versus Conventional Colonoscopy for Improved Endoscopic Performance and Enhanced Patient Experience[NCT01438645] | 250 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| Abdominal Compression Administered Early by the Colonoscopist Shortened Insertion Time of Water Exchange Colonoscopy[NCT03954561] | 120 participants (Actual) | Interventional | 2017-05-15 | Completed | |||
| Does Preoperative Midazolam Dose Affect Postoperative Pain? - a Multicentric Observational Study in Open Inguinal Hernia Repair[NCT03499730] | 300 participants (Actual) | Observational | 2018-09-12 | Completed | |||
| Effect of Ketamine Versus Sevoflurane On The Right Ventricular Pressure During Congenital Pulmonary Stenosis Balloon Dilatation[NCT05582213] | 40 participants (Actual) | Interventional | 2022-10-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Number of Participants Administered Additional Pain Medications
After the procedure, research personnel will ask anesthetist what medications, if any, they gave outside of the study protocol (NCT04871425)
Timeframe: Immediately postoperatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine | 23 |
| Fentanyl | 30 |
Provider Satisfaction With Anesthesia Assessed by the VAS
After the procedure, research personnel will assess provider's satisfaction with patient's anesthesia on a 100mm visual analog scale. The minimum score is 0mm and the maximum score if 100mm, with higher scores indicating higher satisfaction. (NCT04871425)
Timeframe: Immediately postoperatively
| Intervention | score on a scale (Mean) |
|---|---|
| Ketamine | 90 |
| Fentanyl | 86.8 |
Satisfaction With Anesthesia Assessed by the ISAS
After the procedure, either at time of discharge (if less than 30 minutes) or at 30 minutes (if not yet discharged), research personnel will assess the participant's satisfaction with anesthesia using the Iowa Satisfaction with Anesthesia Scale. This is a validated perioperative anesthesia satisfaction scale with a minimum score of -3 and a maximum score of +3 with higher scores indicating higher satisfaction. (NCT04871425)
Timeframe: At discharge or 30 minutes after the procedure
| Intervention | score on a scale (Mean) |
|---|---|
| Ketamine | 2.4 |
| Fentanyl | 2.2 |
Postoperative Pain Assessed by the VAS
Patients will complete 2 followup surveys asking about their postoperative pain after discharge. This will be assessed on a 100mm visual analog scale. The minimum score is 0mm and the maximum score if 100mm, with higher scores indicating higher pain levels. (NCT04871425)
Timeframe: 24 hours postoperatively and 7 days postoperatively
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pain post-op day 1 | Pain post-op day 7 | |
| Fentanyl | 22 | 19.1 |
| Ketamine | 24.5 | 18.2 |
Satisfaction With Anesthesia (Iowa Satisfaction With Anesthesia Scale [ISAS])
The Iowa Satisfaction with Anesthesia Scale (ISAS) was given to women following a surgical abortion. The ISAS score is the mean of 11 responses to questions regarding satisfaction with anesthesia and has a score range of -3 (disagree strongly) to 3 (agree strongly). (NCT02755090)
Timeframe: Assessed 30 minutes after procedure completion.
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide and IV Saline | 0.7 |
| Standard Care Group (IV Sedation and Oxygen) | 1.8 |
Visual Analog Scale (VAS) Score for Maximum Procedural Pain
To compare women's maximum procedural pain measured on a visual analog scale (VAS) during a surgical abortion between 12 weeks 0 days to 16 weeks 0 days gestational age between women randomized to nitrous oxide versus intravenous sedation. A score of 0 represents no pain and a score of 100 represents pain as bad as it could be. (NCT02755090)
Timeframe: Assessed immediately following completion of the procedure (as defined as removal of the speculum)
| Intervention | units on a scale (Mean) |
|---|---|
| Nitrous Oxide and IV Saline | 54.1 |
| Standard Care Group (IV Sedation and Oxygen) | 34.0 |
Effect of Low-dose Ketamine (LDK) on Opioid Usage in the ED
Opioid usage for at least one but up to three prior patient visits in the last one year for each patient enrolled in the study was summarized, expressed as morphine equivalents in mg/kg/h, to account for different types of opioids used per patient preference, and then this was compared to the intervention group that received LDK. Percent change in opioid usage (expressed as morphine equivalents in mg/kg/h) is reported). (NCT03296345)
Timeframe: Up to one year prior and after LDK administration on day 1 of the study in the ED
| Intervention | percent change (Mean) |
|---|---|
| Intervention | -15 |
Effect of Low-dose Ketamine on Discharge Rates From the ED
"Percent discharge from the ED for intervention group and for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. Participants were assigned a 0 if discharged or 1 if not discharged." (NCT03296345)
Timeframe: Up to one year prior to receipt of ketamine for the historical control arm/group and up to 18 months for the intervention arm/group
| Intervention | percentage of participants (Number) |
|---|---|
| Intervention | 33 |
| Historical Control | 17 |
Effect of Low-dose Ketamine on Pain Scores on Presentation to the ED
Patient pain scores at presentation for the enrolled encounters and for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. At least one but up to three prior visits were averaged and compared to the intervention visit. Pain was assessed using the faces pain scale which consists of a series of line diagrams of faces with expressions of increasing distress. The score ranges from 0 (no pain) to 10 (the worst pain). (NCT03296345)
Timeframe: Up to one year prior and on presentation to the ED after LDK administration
| Intervention | Score on a scale (Mean) |
|---|---|
| Intervention | 9.23 |
| Historical Control | 9.08 |
Effect of Low-dose Ketamine on Patient Pain Scores on Discharge From the ED/Admission to the Hospital
Patient pain scores at time of discharge from the ED/admission to the hospital for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. At least one but up to three prior visits were averaged and compared to the intervention visit. Pain scores post receipt of ketamine are presented for the intervention group. Pain was assessed using the faces pain scale which consists of a series of line diagrams of faces with expressions of increasing distress. The score ranges from 0 (no pain) to 10 (the worst pain). (NCT03296345)
Timeframe: At time of discharge from the ED/admission to the hospital (up to one year prior and after LDK administration)
| Intervention | Score on a scale (Mean) |
|---|---|
| Intervention | 7.15 |
| Historical Control | 7.26 |
Effect of Low-dose Ketamine on Percent Difference of Length of Stay (LOS) in the ED
Length of stay (LOS) in minutes in the ED for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed. (NCT03296345)
Timeframe: Up to one year prior to and after LDK administration on day 1 of the study in the ED
| Intervention | LOS in minutes (Mean) |
|---|---|
| Intervention | 273.5 |
| Historical Control | 217.3 |
Effect of Low-dose Ketamine on Time to 50% Pain Reduction
Time to 50% pain reduction (pain reported 50% less than baseline) in minutes for at least one but up to three visits prior to receipt of ketamine in the last one year, were assessed as historical controls. Pain was assessed using the faces pain scale which consists of a series of line diagrams of faces with expressions of increasing distress. The score ranges from 0 (no pain) to 10 (the worst pain). (NCT03296345)
Timeframe: Up to one year prior to and after LDK administration on day 1 of the study in the ED
| Intervention | time to 50% pain reduction in minutes (Mean) |
|---|---|
| Intervention | 116.1 |
| Historical Control | 167.3 |
Subjective Effect of Low Dose Ketamine on Pain Relief Assessed Via a Patient Survey
"After receipt of LDK, patients and/or their parents, based on age, filled out a survey based on a Likert scale regarding their agreement (Strongly Disagree to Strongly Agree) with the following statements: Achieved faster pain relief with LDK, Achieved more complete pain relief with LDK, and Desire to receive LDK in a future vaso-occlusive crisis. There is also an area where patients could provide general comments regarding their experience in receiving LDK.~Count of Participants who agree or strongly agree for each question are reported." (NCT03296345)
Timeframe: after LDK administration on day 1 of the study in the ED
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Achieved faster pain relief? | Achieved more complete pain relief? | Desire to receive LDK in the future? | |
| Intervention | 43 | 30 | 49 |
Quality of Recovery Score Post Operative at 24 Hours
Quality of recovery 40 score at 24 hours after the surgical procedure. 40 being a poor recovery and 200 being a good recovery. (NCT01106846)
Timeframe: 24 hours post operative
| Intervention | units on scale (Mean) |
|---|---|
| Group A: Saline Group | 191.2 |
| Group B: 1% Ketamine Group | 191.1 |
Length of Time From Extubation to Discharge From Postanesthesia Recovery Unit
Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours
| Intervention | minutes (Mean) |
|---|---|
| Placebo | 53.5 |
| Modafinil | 61.0 |
Postanesthesia Quality Recovery Scale Score
Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | -5.67 |
| Modafinil | -8.91 |
Average Total Propofol Consumption Per Group
Total propofol consumption per subject was measured as μg/kg/min of procedure in minutes. The average propofol consumption in each group will be measured as secondary outcome. (NCT03139279)
Timeframe: between 7 and 57 minutes (median 19 min)
| Intervention | μg/kg/min (Median) |
|---|---|
| Dexmedetomidine and Propofol | 140 |
| Saline Placebo and Propofol | 180 |
Lowest Intraoperative % Change in MAP From Baseline
Lowest intraoperative percent (%) change in mean arterial pressure (MAP) from baseline (average in each group) (NCT03139279)
Timeframe: 30 minutes
| Intervention | percentage change (Mean) |
|---|---|
| Dexmedetomidine and Propofol | 30 |
| Saline Placebo and Propofol | 21 |
Number of Participants With Apneic Episodes Intraoperatively Requiring Positive Pressure Ventilation
Incidence of apneic episodes intraoperatively requiring positive pressure ventilation in each group (NCT03139279)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Dexmedetomidine and Propofol | 0 |
| Saline Placebo and Propofol | 0 |
Percentage of Subjects Ready for Discharge in Each Group at 30 Minutes Post Procedure
Each subject was assessed for readiness for discharge at 10, 20 and 30 minutes after the procedure, using the Modified Post-Anesthesia Discharge Scoring System (MPADSS). A subject getting an MPADS score of 9-10 is deemed ready for discharge. The percentage of subjects ready for discharge in each group at 10, 20 and 30 minutes will be measured as primary outcome. (NCT03139279)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Dexmedetomidine and Propofol | 26 |
| Saline Placebo and Propofol | 44 |
Colonoscopy Success With Minimal Sedation
(NCT00671177)
Timeframe: At the time of the procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Water Immersion Colonoscopy | 57 |
| Standard Air Colonoscopy | 32 |
Patient Satisfaction
Patient satisfaction was measured on a scale of 1 (best) to 7 (worst). (NCT00671177)
Timeframe: At the time of the procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Water Immersion Colonoscopy | 1.09 |
| Standard Air Colonoscopy | 1.26 |
Time to Cecum
(NCT00671177)
Timeframe: At the time of the procedure
| Intervention | minutes (Mean) | |
|---|---|---|
| Attending | Trainee | |
| Standard Air Colonoscopy | 7.2 | 20.5 |
| Water Immersion Colonoscopy | 5.4 | 13 |
Number of Participants That Experienced Nausea or Vomiting
Total times during 48h after cesarean section. (NCT03065530)
Timeframe: 48h after cesarean section.
| Intervention | participants (Number) |
|---|---|
| Group C | 1 |
| Group D1 | 2 |
| Group D2 | 1 |
| Group D3 | 1 |
Postoperative Pain Score (Visual Analogue Scale, VAS)
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS at rest was assessed when the patient was in supine position (NCT03065530)
Timeframe: 48h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 2.11 |
| Group D1 | 2 |
| Group D2 | 1.72 |
| Group D3 | 125 |
Postoperative Pain Score (Visual Analogue Scale, VAS) at Rest
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS at rest was assessed when the patient was in supine position (NCT03065530)
Timeframe: 12h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.29 |
| Group D1 | 2.86 |
| Group D2 | 1.62 |
| Group D3 | 0.93 |
Postoperative Pain Score (Visual Analogue Scale, VAS) at Rest
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS at rest was assessed when the patient was in supine position (NCT03065530)
Timeframe: 24h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.21 |
| Group D1 | 2.93 |
| Group D2 | 1.72 |
| Group D3 | 1.57 |
Postoperative Pain Score (Visual Analogue Scale, VAS) at Rest
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS at rest was assessed when the patient was in supine position (NCT03065530)
Timeframe: 6h after cesarean section.
| Intervention | units on a scale (Mean) |
|---|---|
| Group C | 3.143 |
| Group D1 | 2.897 |
| Group D2 | 1.665 |
| Group D3 | 1.25 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Movement
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS on movement was assessed when patients changed from supine to lateral position. (NCT03065530)
Timeframe: 12h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.71 |
| Group D1 | 3.52 |
| Group D2 | 2.69 |
| Group D3 | 1.18 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Movement
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS on movement was assessed when patients changed from supine to lateral position. (NCT03065530)
Timeframe: 24h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.82 |
| Group D1 | 3.79 |
| Group D2 | 2.35 |
| Group D3 | 1.93 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Movement
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS on movement was assessed when patients changed from supine to lateral position. (NCT03065530)
Timeframe: 48h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.43 |
| Group D1 | 3.28 |
| Group D2 | 2.24 |
| Group D3 | 1.21 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Movement
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS on movement was assessed when patients changed from supine to lateral position. (NCT03065530)
Timeframe: 6h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 4.39 |
| Group D1 | 4.31 |
| Group D2 | 2.86 |
| Group D3 | 2.2 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Uterine Cramping
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS-C was assessed when the patient required oxytocin after surgery in supine position (NCT03065530)
Timeframe: 12h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.46 |
| Group D1 | 3.41 |
| Group D2 | 2.17 |
| Group D3 | 1.07 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Uterine Cramping
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS-C was assessed when the patient required oxytocin after surgery in supine position (NCT03065530)
Timeframe: 24h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.75 |
| Group D1 | 3.55 |
| Group D2 | 2.59 |
| Group D3 | 1.79 |
Postoperative Pain Score (Visual Analogue Scale, VAS) on Uterine Cramping
visual analogue scale (VAS; with 0, no pain; to 10, the worst imaginable pain) is a validated assessing scale for pain intensity. VAS-C was assessed when the patient required oxytocin after surgery in supine position (NCT03065530)
Timeframe: 6h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 3.86 |
| Group D1 | 3.66 |
| Group D2 | 2.79 |
| Group D3 | 2 |
Ramsay Sedation Score(RSS)
Sedation intensity measured with RSS is recorded at the 6, 12 24 and 48 h after cesarean section. Sedation was assessed by the Ramsay Sedation Scores (RSS) (1, anxious patient; 2, cooperative and tranquil; 3, responding to command; 4, brisk response to stimulus; 5, sluggish response to stimulus; 6, no response to stimulus). (NCT03065530)
Timeframe: 6h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Control Group | 2 |
| Dexmedetomidine 0.03ug/kg/h Group | 2.17 |
| Dexmedetomidine 0.05ug/kg/h Group | 2.14 |
| Dexmedetomidine 0.08ug/kg/h Group | 3.14 |
Ramsay Sedation Score(RSS)
Sedation intensity measured with RSS is recorded at the 6, 12, 24, and 48 h after cesarean section. Sedation was assessed by the Ramsay Sedation Scores (RSS) (1, anxious patient; 2, cooperative and tranquil; 3, responding to command; 4, brisk response to stimulus; 5, sluggish response to stimulus; 6, no response to stimulus). (NCT03065530)
Timeframe: 12h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 2 |
| Group D1 | 2.21 |
| Group D2 | 2.28 |
| Group D3 | 3.21 |
Ramsay Sedation Score(RSS)
Sedation intensity measured with RSS is recorded at the 6, 12, 24, and 48 h after cesarean section. Sedation was assessed by the Ramsay Sedation Scores (RSS) (1, anxious patient; 2, cooperative and tranquil; 3, responding to command; 4, brisk response to stimulus; 5, sluggish response to stimulus; 6, no response to stimulus). (NCT03065530)
Timeframe: 24h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 2 |
| Group D1 | 2.07 |
| Group D2 | 2.10 |
| Group D3 | 2.25 |
Ramsay Sedation Score(RSS)
Sedation intensity measured with RSS is recorded at the 6, 12, 24, and 48 h after cesarean section. Sedation was assessed by the Ramsay Sedation Scores (RSS) (1, anxious patient; 2, cooperative and tranquil; 3, responding to command; 4, brisk response to stimulus; 5, sluggish response to stimulus; 6, no response to stimulus). (NCT03065530)
Timeframe: 48h after cesarean section.
| Intervention | score on a scale (Mean) |
|---|---|
| Group C | 2 |
| Group D1 | 2 |
| Group D2 | 2 |
| Group D3 | 2 |
Relative Infant Dose (RID) of Dexmedetomidine
Relative infant dose (RID) =Dose (infant, mg•kg-1•day-1) /Dose (mother, mg•kg-1•day-1) μg·kg-1·h-1. The Dose (infant) in mg•kg-1 is calculated by multiplying the concentration of the drug in breast milk by the volume of breast milk consumed daily (about 150 mL•kg-1). (NCT03065530)
Timeframe: 48h after cesarean section.
| Intervention | percentage of one hundred (Mean) |
|---|---|
| Group D1 | 0.1712 |
| Group D2 | 0.1967 |
| Group D3 | 0.3701 |
The Degree of Satisfaction
The degree of satisfaction (0, very satisfied; 1, satisfied; 2, moderately satisfied; 3, not satisfied) was evaluated at 48 h after surgery. The number of overall satisfied patients (satisfied and very satisfied) is reported. (NCT03065530)
Timeframe: 48h after cesarean section.
| Intervention | Participants (Count of Participants) |
|---|---|
| Group C | 12 |
| Group D1 | 16 |
| Group D2 | 26 |
| Group D3 | 25 |
Duration of Mechanical Ventilation
Number of days patient requires mechanical ventilation (NCT02203019)
Timeframe: Up to 28 days
| Intervention | days (Median) |
|---|---|
| Propofol | 5 |
| Dexmedetomidine | 3 |
Duration of MICU Stay
Number of days patient stays in the MICU (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | days (Median) |
|---|---|
| Propofol | 6 |
| Dexmedetomidine | 5 |
Duration of Vasopressor Support
Number of days the patient requires intravenous vasopressors (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | days (Median) |
|---|---|
| Propofol | 0 |
| Dexmedetomidine | 2 |
Mortality
Number of patients who die within 28 days after randomization (NCT02203019)
Timeframe: Up to 28 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Propofol | 8 |
| Dexmedetomidine | 9 |
Hospital Length of Stay
Index hospitalization length of stay in days (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 19.5 |
| Propofol or Dexmedetomidine | 30.0 |
In Hospital Mortality
All-cause mortality during the hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | participants (Number) |
|---|---|
| Midazolam | 1 |
| Propofol or Dexmedetomidine | 1 |
Intensive Care Unit Length of Stay
Number of days of admission to the CICU during the index hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 4.1 |
| Propofol or Dexmedetomidine | 10.0 |
Number of Days Alive During Admission and Free From Delirium or Coma
The number of days alive and free from delirium or coma during admission will be evaluated among patients with CAM-ICU documented (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 14.0 |
Number of Days From Decision to Extubate to True Extubation
The time (in days) from when the clinical care team documents a decision to pursue extubation until the time the patient was extubated (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 0 |
Number of Participants Requiring Reintubation
Following ICU discharge, patient charts will be reviewed to evaluate whether they required reintubation. If so, will determine whether necessity of reintubation was related to delirium. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 1 |
Number of Participants With Bradycardia
Patients will be monitored for bradycardia which may be associated with sedation drug. Average heart rate before, during and after use of drug will be recorded for each patient. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 0 |
| Propofol or Dexmedetomidine | 0 |
Number of Participants With Delirium
Will use the Confusion Assessment Method for the ICU (CAM-ICU) to assess presence of delirium as per standard of care by nurses in the CICU. Patients with CAM-ICU data recorded will be included. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 1 |
Number of Participants With Increased Vasopressor Requirement
Patients will be monitored for increased pressor requirement during the CICU stay (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Participants (Count of Participants) |
|---|---|
| Midazolam | 2 |
| Propofol or Dexmedetomidine | 2 |
Number of Ventilator Days
Days requiring mechanical ventilation during the initial episode of intubation during the hospitalization (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 2.5 |
| Propofol or Dexmedetomidine | 6.8 |
Pain Management
Will use the CPOT (Critical-Care Pain Observation Tool) score to assess pain level as per standard of care by nurses in the CICU. The CPOT has a range of 0 to 8. A CPOT score of ≤ 2 = minimal to no pain present and >2 = unacceptable level of pain. Data that is recorded will be evaluated following discharge. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | score on a scale (Median) |
|---|---|
| Midazolam | 0.0 |
| Propofol or Dexmedetomidine | 0.0 |
Percentage of Time at Goal Sedation
Will use RASS (Richmond Agitation and Sedation Scale) to assess level of sedation as per standard of care by nurses in the CICU. Data that is recorded will be evaluated following discharge. The RASS ranges from -5 (unrousable) to +4 (combative) and 0 (zero) = alert and calm and goal sedation is considered a RASS level of 0 to -2. (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | percentage of time (Median) |
|---|---|
| Midazolam | 63.3 |
| Propofol or Dexmedetomidine | 63.2 |
Time From Withdrawal of Sedation to ICU Discharge
The duration, in days, from withdrawal of sedation for mechanical ventilation until the time of discharge from the ICU (NCT02903407)
Timeframe: One month or hospital discharge, whichever time point comes first
| Intervention | Days (Median) |
|---|---|
| Midazolam | 1.6 |
| Propofol or Dexmedetomidine | 5.6 |
Maternal Breastfeeding 7-15 Days After Discharge
Maternal breastfeeding means: exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At the first follow-up visit (7-15 days after discharge)
| Intervention | participants (Number) |
|---|---|
| Control | 32 |
| Music Therapy | 42 |
Maternal Breastfeeding at 30 Days After Discharge
Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At 30 days after the infant hospital discharge
| Intervention | participants (Number) |
|---|---|
| Control | 30 |
| Music Therapy | 38 |
Maternal Breastfeeding at 60 Days After Discharge
Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At 60 days after the infant hospital discharge
| Intervention | participants (Number) |
|---|---|
| Control | 27 |
| Music Therapy | 36 |
Maternal Breastfeeding at Infant Discharge
Maternal breastfeeding means exclusive maternal breastfeeding, predominant maternal breastfeeding (maternal milk associated to other liquid, except formula) and continuous maternal breastfeeding (maternal milk associate to other food, including formula). (NCT00930761)
Timeframe: At the time of the infant hospital discharge
| Intervention | participants (Number) |
|---|---|
| Control | 33 |
| Music Therapy | 42 |
Event of Hypoxia
Hypoxia defined as peripheral blood oxygen saturation measured by pulse oxymeter < 90% (NCT02027311)
Timeframe: Every 5min in Preoperative, intraoperative phase and 15 min in Recovery phase
| Intervention | Hypoxia events (Number) |
|---|---|
| Midazolam | 19 |
| Etomidate | 27 |
Number of Intervention
The frequency of intervention which was defined as any restraint of the patient's head, arms, or legs if they became agitated, or if patient movement was not controlled with verbal instruction from the endoscopist during the whole intraoperative phases. (NCT02027311)
Timeframe: Throughout the whole ERCP procedure
| Intervention | Number of intervention (Mean) |
|---|---|
| Etomidate | 1.9 |
| Midazolam | 7.5 |
Insertion Time
Time to cecum (clock display on monitor), faster insertion is a quality marker (NCT03160859)
Timeframe: Insertion time in minutes was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Minutes (Mean) |
|---|---|
| Control Method | 18.8 |
| Study Method | 18.6 |
Proportion of Patients With No Insertion Pain
Proportion of patients who report no pain during insertion of the colonoscope. (NCT03160859)
Timeframe: Pain was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Method | 38 |
| Study Method | 41 |
Real Time Maximum Insertion Pain
Pain during insertion reported to the unblinded assisting nurse, visual analogue scale, VAS: 0=none, 10=most severe. The highest pain score will be tabulated for analysis. Timing of data collection will be at the discretion of the nurse to minimize bias by colonoscopist behavior. (NCT03160859)
Timeframe: Insertion pain was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | score on a scale (Mean) |
|---|---|
| Control Method | 2.6 |
| Study Method | 2.9 |
Right Colon Adenoma Detection Rate (ADR)
Right colon Adenoma Detection Rate (ADR) is the proportion of patients with at least one adenoma in the part of the colon between the cecum and the hepatic flexure. (NCT03160859)
Timeframe: Adenoma Detection Rate (ADR) was measured during the duration of the colonoscopy procedure, which lasted on average for about 1 hour
| Intervention | Participants (Count of Participants) |
|---|---|
| Control Method | 40 |
| Study Method | 27 |
Observational Score Behavioral Distress Revised (OSBD-R)
Weighted average Observational Score Behavioral Distress Revised (OSBD-R) scored from videotapes of the entire laceration repair procedure Scale 0-23.5 (0 low/better, 23.5 high/worse) (NCT02217436)
Timeframe: Entire laceration repair procedure
| Intervention | units on a scale (Median) |
|---|---|
| iPad | 2.3 |
| Standard Care | 0.8 |
Parent Survey
Parent rating of own anxiety during the procedure Likert-based scale 1-5 (1 low/better, 5 high/worse) (NCT02217436)
Timeframe: Survey administered immediately following the laceration repair
| Intervention | score on a scale (Median) |
|---|---|
| iPad | 2 |
| Standard Care | 4 |
Reviews
19 reviews available for midazolam and Ache
| Article | Year |
|---|---|
Sedoanalgesia with intravenous midazolam and fentanyl for angioplasty of dysfunctional arteriovenous access: A retrospective single-center analysis.
Topics: Aged; Angioplasty; Angioplasty, Balloon; Arteriovenous Shunt, Surgical; Fentanyl; Graft Occlusion, V | 2023 |
Palliative Sedation at Home: A Scoping Review.
Topics: Adult; Child; Death; Dyspnea; Humans; Hypnotics and Sedatives; Midazolam; Neoplasms; Pain; Palliativ | 2023 |
The effect of adjuvants added to local anaesthetics for single-injection upper extremity peripheral regional anaesthesia: A systematic review with network meta-analysis of randomised trials.
Topics: Anesthesia, Conduction; Anesthetics, Local; Dexamethasone; Dexmedetomidine; Humans; Ketorolac; Midaz | 2023 |
Pharmacological pain and sedation interventions for the prevention of intraventricular hemorrhage in preterm infants on assisted ventilation - an overview of systematic reviews.
Topics: Acetaminophen; Analgesics, Opioid; Cerebral Hemorrhage; Female; Heroin; Humans; Ibuprofen; Infant, N | 2023 |
Procedural (Conscious) Sedation and Analgesia in Emergency Setting: How to Choose Agents?
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Conscious Sedation; Humans; Hypnotics and Sedative | 2023 |
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; C | 2019 |
Palliative sedation: A safety net for the relief of refractory and intolerable symptoms at the end of life.
Topics: Aged; Analgesics; Conscious Sedation; Dehydration; Dyspnea; Humans; Hydromorphone; Hypnotics and Sed | 2019 |
Anaesthetic management of subcutaneous abscesses: current status.
Topics: Abscess; Administration, Topical; Anesthesia; Anesthetics, Dissociative; Anesthetics, Local; Drainag | 2020 |
Nitrous oxide provides safe and effective analgesia for minor paediatric procedures--a systematic review.
Topics: Adolescent; Analgesia; Analgesics, Non-Narcotic; Catheterization, Peripheral; Child; Child, Preschoo | 2013 |
Sedation and analgesia to facilitate mechanical ventilation.
Topics: Analgesics; Analgesics, Opioid; Benzodiazepines; Clonidine; Humans; Hypnotics and Sedatives; Infant; | 2013 |
Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics, Opioid; Dexmedetomidine; | 2011 |
Pain relief in the treatment of shoulder injury.
Topics: Analgesics; Conscious Sedation; Humans; Hypnotics and Sedatives; Midazolam; Morphine; Nitrous Oxide; | 2011 |
A systematic review of interventions for reducing pain and distress in children undergoing voiding cystourethrography.
Topics: Anesthetics, Inhalation; Anxiety; Child; Fluoroscopy; Hot Temperature; Humans; Hypnotics and Sedativ | 2012 |
[Sedation and analgesia in emergency structure. Paediatry: Which sedation and analgesia for the child under spontaneous ventilation?].
Topics: Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, Local; Anesthetics, D | 2012 |
Combination spinal analgesic chemotherapy: a systematic review.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Local; Antineoplastic Agents; Cholineste | 2002 |
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; | 2004 |
The neurochemistry of central pain: evidence from clinical studies, hypothesis and therapeutic implications.
Topics: Anesthetics, Intravenous; Baclofen; Cerebral Cortex; GABA Agonists; gamma-Aminobutyric Acid; Glutami | 1998 |
Promising non-narcotic analgesic techniques for labour.
Topics: Analgesia, Obstetrical; Analgesics, Non-Narcotic; Clonidine; Epinephrine; Female; Humans; Midazolam; | 1998 |
Comparing drugs for short-term sedation.
Topics: Anesthesia; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Lorazepam; Midazolam; | 1994 |
Trials
143 trials available for midazolam and Ache
| Article | Year |
|---|---|
Dexmedetomidine Versus Midazolam for Sedation During Medical Thoracoscopy: A Pilot Randomized-Controlled Trial (RCT).
Topics: Analgesics, Opioid; Conscious Sedation; Cough; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Seda | 2022 |
Randomized single-blind comparative study of the midazolam/pethidine combination and midazolam alone during bronchoscopy.
Topics: Bronchoscopy; Conscious Sedation; Humans; Meperidine; Midazolam; Pain; Prospective Studies; Single-B | 2022 |
Discharge readiness after remimazolam versus propofol for colonoscopy: A randomised, double-blind trial.
Topics: Adult; Benzodiazepines; Bradycardia; Colonoscopy; Humans; Hypnotics and Sedatives; Hypotension; Mida | 2022 |
Ketamine Compared With Fentanyl for Surgical Abortion: A Randomized Controlled Trial.
Topics: Double-Blind Method; Female; Fentanyl; Humans; Ketamine; Midazolam; Pain; Pregnancy | 2022 |
Comparison of Propofol-Fentanyl with Midazolam-Ketamine Combination in Pediatric Patients Undergoing Kidney Biopsy.
Topics: Analgesics; Biopsy; Child; Fentanyl; Humans; Ketamine; Kidney; Midazolam; Pain; Propofol | 2022 |
Comparison of 2 effect-site concentrations of remifentanil with midazolam during transrectal ultrasound-guided prostate biopsy under procedural analgesia and sedation: A randomized controlled study.
Topics: Analgesia, Patient-Controlled; Biopsy; Double-Blind Method; Humans; Male; Midazolam; Pain; Piperidin | 2022 |
Value of Music and Nitrous Oxide for Pain Control during Extracorporeal Shock Wave Lithotripsy (ESWL).
Topics: Analgesics; Fentanyl; Humans; Ketoprofen; Lithiasis; Lithotripsy; Midazolam; Music; Nitrous Oxide; P | 2022 |
The efficacy and safety of midazolam with fentanyl versus midazolam with ketamine for bedside invasive procedural sedation in pediatric oncology patients: A randomized, double-blinded, crossover trial.
Topics: Child; Cross-Over Studies; Fentanyl; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Neoplasms | 2022 |
Gabapentin as an adjunct for pain management during dilation and evacuation: A double-blind randomized controlled trial.
Topics: Dilatation; Double-Blind Method; Female; Fentanyl; Gabapentin; Humans; Midazolam; Nausea; Pain; Pain | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Effect of Rectal Midazolam on Pain, Stress, and Cooperation of Patient during Urodynamic Test in Women: A Randomized Clinical Trial.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Midazolam; Pain; Stress, Physiological; Urodynami | 2023 |
Continuous peripheral nerve blocks for analgesia of ventilated critically ill patients with multiple trauma: a prospective randomized study.
Topics: Analgesia; Analgesics, Opioid; Critical Illness; Female; Humans; Hypnotics and Sedatives; Intensive | 2023 |
Continuous peripheral nerve blocks for analgesia of ventilated critically ill patients with multiple trauma: a prospective randomized study.
Topics: Analgesia; Analgesics, Opioid; Critical Illness; Female; Humans; Hypnotics and Sedatives; Intensive | 2023 |
Continuous peripheral nerve blocks for analgesia of ventilated critically ill patients with multiple trauma: a prospective randomized study.
Topics: Analgesia; Analgesics, Opioid; Critical Illness; Female; Humans; Hypnotics and Sedatives; Intensive | 2023 |
Continuous peripheral nerve blocks for analgesia of ventilated critically ill patients with multiple trauma: a prospective randomized study.
Topics: Analgesia; Analgesics, Opioid; Critical Illness; Female; Humans; Hypnotics and Sedatives; Intensive | 2023 |
Efficacy of median nerve hydrodissection by hyalase versus midazolam in the treatment of carpal tunnel syndrome.
Topics: Bupivacaine; Carpal Tunnel Syndrome; Double-Blind Method; Humans; Median Nerve; Midazolam; Pain | 2023 |
Real-time evaluation of the independent analgesic efficacy of dexmedetomidine.
Topics: Analgesia; Analgesics; Dexmedetomidine; Humans; Midazolam; Pain | 2023 |
Brain connectivity under light sedation with midazolam and ketamine during task performance and the periodic experience of pain: Examining concordance between different approaches for seed-based connectivity analysis.
Topics: Adult; Brain; Humans; Ketamine; Magnetic Resonance Imaging; Midazolam; Pain; Task Performance and An | 2023 |
Topical Lidocaine And Or/ Intravenous Midazolam Before Radial Coronary Angiography To Prevent Radial Artery Spasm.
Topics: Cardiac Catheterization; Coronary Angiography; Female; Humans; Lidocaine; Male; Midazolam; Pain; Per | 2023 |
Postoperative recovery in preschool-aged children: A secondary analysis of a randomized controlled trial comparing premedication with midazolam, clonidine, and dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, General; Child; Child, Preschool; Clonidine; Dexme | 2023 |
The effectiveness of topical lidocaine in relieving pain related to intranasal midazolam sedation: a randomized, placebo-controlled clinical trial.
Topics: Administration, Intranasal; Child; Child, Preschool; Double-Blind Method; Humans; Lidocaine; Midazol | 2020 |
Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain.
Topics: Adolescent; Adult; Analgesics; Anesthetics, Intravenous; Brain; Cross-Over Studies; Fear; Female; Hu | 2021 |
Midazolam as an active placebo in 3 fentanyl-validated nociceptive pain models.
Topics: Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Fentanyl; Healthy Volunteers; Hu | 2017 |
Effects of sedation on subjective perception of pain intensity and autonomic nervous responses to pain: A preliminary study.
Topics: Adult; Anesthetics, Intravenous; Autonomic Nervous System; Conscious Sedation; Humans; Hypnotics and | 2017 |
Nitrous Oxide Compared With Intravenous Sedation for Second-Trimester Abortion: A Randomized Controlled Trial.
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, | 2018 |
Moderate procedural sedation and opioid analgesia during transradial coronary interventions to prevent spasm: a prospective randomized study.
Topics: Aged; Analgesics, Opioid; Arterial Occlusive Diseases; Chi-Square Distribution; Conscious Sedation; | 2013 |
A double-blind, randomised, placebo-controlled trial of oral midazolam plus oral ketamine for sedation of children during laceration repair.
Topics: Administration, Oral; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Double | 2014 |
Magnetic endoscopic imaging during colonoscopy is associated with less pain and decreased need of analgesia and sedation--results from a randomized controlled trial.
Topics: Adult; Aged; Analgesics, Opioid; Cecum; Colonoscopy; Female; Humans; Hypnotics and Sedatives; Imagin | 2013 |
Comparison of procedural sequence in same-day consecutive bidirectional endoscopy using moderate sedation: a prospective randomized study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conscious Sedation; Endoscopy, Gastrointestinal; Female; | 2014 |
Remifentanil versus morphine-midazolam premedication on the quality of endotracheal intubation in neonates: a noninferiority randomized trial.
Topics: Analgesics, Opioid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypnoti | 2014 |
Patient-Controlled Remifentanil Analgesia as Alternative for Pethidine with Midazolam During Oocyte Retrieval in IVF/ICSI Procedures: A Randomized Controlled Trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Intravenous; Drug Therapy, Co | 2015 |
Preemptive dexmedetomidine to prevent propofol injection pain in children.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind | 2015 |
Evaluating the hematoma block as an adjunct to procedural sedation for closed reduction of distal forearm fractures.
Topics: Adolescent; Anesthetics, Local; Child; Child, Preschool; Conscious Sedation; Double-Blind Method; Fe | 2014 |
A comparative study on the sedative effect of oral midazolam and oral chloral hydrate medication in lumbar puncture.
Topics: Administration, Oral; Child; Child, Preschool; Chloral Hydrate; Conscious Sedation; Female; Humans; | 2013 |
Procedural sedation and analgesia as an adjunct to periprostatic nerve block for prostate biopsy: A prospective randomized trial.
Topics: Aged; Anesthetics, Local; Biopsy; Gels; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; | 2015 |
Randomized comparison of recovery time after use of remifentanil alone versus midazolam and meperidine for colonoscopy anesthesia.
Topics: Analgesics, Opioid; Anesthesia; Anesthesia Recovery Period; Anesthetics, Intravenous; Colonoscopy; D | 2015 |
Propofol-alfentanyl versus midazolam-alfentanyl in inducing procedural amnesia of upper gastrointestinal endoscopy in children--blind randomised trial.
Topics: Adolescent; Alfentanil; Analgesics, Opioid; Child; Conscious Sedation; Double-Blind Method; Drug The | 2015 |
Dexmedetomidine Analgesia Effects in Patients Undergoing Dental Implant Surgery and Its Impact on Postoperative Inflammatory and Oxidative Stress.
Topics: Adult; Analgesics, Non-Narcotic; Dental Implants; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay | 2015 |
Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decrease Patients' Pain? (A Pilot Study).
Topics: Adult; Anesthesia; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Huma | 2016 |
[A study of using dexmedetomidine in ventilator bundle treatment in an ICU].
Topics: Arterial Pressure; Blood Pressure; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedati | 2015 |
[The influence of the sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients].
Topics: Analgesia; Arterial Pressure; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sed | 2015 |
Midazolam Plus Haloperidol as Adjuvant Analgesics to Morphine in Opium Dependent Patients: A Randomized Clinical Trial.
Topics: Adult; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drug T | 2016 |
Efficacy of midazolam- versus propofol-based sedations by non-anesthesiologists during therapeutic endoscopic retrograde cholangiopancreatography in patients aged over 80 years.
Topics: Aged, 80 and over; Biliary Tract Diseases; Cholangiopancreatography, Endoscopic Retrograde; Consciou | 2017 |
Nurse-administered propofol sedation compared with midazolam and meperidine for EUS: a prospective, randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anesthesia Recovery Period; Anesthetics, Intravenou | 2008 |
Pediatric oncology sedation trial (POST): A double-blind randomized study.
Topics: Adolescent; Antiemetics; Antineoplastic Agents; Biopsy, Needle; Bone Marrow Examination; Child; Chil | 2008 |
Ketamine and midazolam delivered by patient-controlled analgesia in relieving pain associated with burns dressings.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Bandages; Burns; Drug Therapy, C | 2008 |
Ketamine and midazolam delivered by patient-controlled analgesia in relieving pain associated with burns dressings.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Bandages; Burns; Drug Therapy, C | 2008 |
Ketamine and midazolam delivered by patient-controlled analgesia in relieving pain associated with burns dressings.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Bandages; Burns; Drug Therapy, C | 2008 |
Ketamine and midazolam delivered by patient-controlled analgesia in relieving pain associated with burns dressings.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Bandages; Burns; Drug Therapy, C | 2008 |
Midazolam in conjunction with local anaesthesia is superior to Entonox in providing pain relief during bone marrow aspirate and trephine biopsy.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Combined | 2008 |
Intravenous ketamine plus midazolam vs. intravenous ketamine for sedation in lumbar puncture: a randomized controlled trial.
Topics: Adolescent; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Confidence Intervals; Dizzin | 2008 |
Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy.
Topics: Administration, Inhalation; Adult; Aged; Anesthetics, Combined; Attitude of Health Personnel; Colono | 2009 |
Analgesia during abdominal aortic aneurysm endovascular repair: remifentanil vs. fentanyl-midazolam--a randomized controlled trial.
Topics: Aged; Analgesia; Analgesics, Opioid; Aortic Aneurysm, Abdominal; Area Under Curve; Blood Pressure; C | 2009 |
Comparison of ketamine plus midazolam versus ketamine for sedation in children during lumbar puncture.
Topics: Adjuvants, Anesthesia; Adolescent; Analgesics; Child, Preschool; Drug Therapy, Combination; Female; | 2009 |
Low-dose oral midazolam reduces fear and distress during needle procedures in children with cancer.
Topics: Administration, Oral; Adolescent; Adult; Anxiety; Child; Child, Preschool; Double-Blind Method; Fear | 2009 |
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha | 2010 |
Pain relief during dressing changes of major adult burns: ideal analgesic combination with ketamine.
Topics: Adult; Analgesics; Bandages; Blood Pressure; Burns; Dexmedetomidine; Drug Therapy, Combination; Fema | 2010 |
Transrectal ultrasound-guided prostatic biopsy: midazolam, the ideal analgesic.
Topics: Analgesia; Anesthetics, Intravenous; Biopsy; Humans; Male; Midazolam; Pain; Prospective Studies; Pro | 2009 |
The effect of single-dose propofol injection on pain and quality of life in chronic daily headache: a randomized, double-blind, controlled trial.
Topics: Adult; Analgesics; Disability Evaluation; Double-Blind Method; Drug Administration Schedule; Female; | 2009 |
[Effects of intravenous midazolam, fentanyl or ketamine on pain relief during performance of epidural anesthesia].
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Epidural; Female; Fentanyl; Humans; Hypnoti | 2009 |
Sedation with midazolam versus midazolam plus meperidine for routine colonoscopy: a prospective, randomized, controlled study.
Topics: Adult; Aged; Analgesics, Opioid; Blood Pressure; Colonoscopy; Conscious Sedation; Drug Therapy, Comb | 2009 |
Effects of premedication of midazolam or clonidine on perioperative anxiety and pain in children.
Topics: Administration, Oral; Analgesics; Anti-Anxiety Agents; Anxiety; Child; Child, Preschool; Clonidine; | 2009 |
The effect of a 3 : 1 volume mixture of propofol 1% and thiopental 2.5% in reducing the pain on injection of propofol in children.
Topics: Adolescent; Age Factors; Algorithms; Anesthetics, Combined; Anesthetics, Intravenous; Blood Pressure | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmede | 2010 |
Comparison of paravertebral block versus fast-track general anesthesia via laryngeal mask airway in outpatient inguinal herniorrhaphy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Anesth | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Water immersion versus standard colonoscopy insertion technique: randomized trial shows promise for minimal sedation.
Topics: Air; Colonoscopy; Conscious Sedation; Humans; Hypnotics and Sedatives; Immersion; Insufflation; Mida | 2010 |
Predominant effects of midazolam for conscious sedation: benefits beyond the early postoperative period.
Topics: Adult; Aged; Anesthetics, Local; Blood Pressure; Conscious Sedation; Electrocardiography; Female; He | 2010 |
Pain management in young children undergoing diagnostic tympanocentesis.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Biopsy, Fine-Needle; Chi | 2011 |
Middle-ear surgery under sedation: comparison of midazolam alone or midazolam with remifentanil.
Topics: Adult; Anesthetics, Local; Anxiety; Conscious Sedation; Dizziness; Drug Therapy, Combination; Ear, M | 2011 |
Comparison of a morphine and midazolam combination with morphine alone for paediatric displaced fractures: a randomized study.
Topics: Administration, Oral; Administration, Sublingual; Adolescent; Analgesics, Opioid; Child; Child, Pres | 2011 |
Midazolam-ketamine combination for moderate sedation in upper GI endoscopy.
Topics: Adjuvants, Anesthesia; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Deep | 2012 |
Analgesia and endocrine surgical stress: effect of two analgesia protocols on cortisol and prolactin levels during abdominal aortic aneurysm endovascular repair.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Analgesics, Opioid; Aortic Aneurysm, Abdomina | 2011 |
Sevoflurane to alleviate pain on propofol injection.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Female; Fentanyl; Humans; Injections, Intr | 2011 |
Moderate sedation for elective upper endoscopy with balanced propofol versus fentanyl and midazolam alone: a randomized clinical trial.
Topics: Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Deep Sedation; Endoscopy, Digesti | 2012 |
Intravenous ketamine is as effective as midazolam/fentanyl for procedural sedation and analgesia in the emergency department.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Conscious Sedation; Emergency | 2011 |
Music during interventional radiological procedures, effect on sedation, pain and anxiety: a randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anxiety; Female; Fentanyl; Humans; Hypnotics | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypno | 2012 |
Effects of midazolam and nitrous oxide on endocrine and metabolic measurements in children.
Topics: Adolescent; Anesthetics, Local; Blood Glucose; Blood Specimen Collection; Catheterization, Periphera | 2012 |
Warm water infusion during sedated colonoscopy does not decrease amount of sedation medication used.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cold Temperature; Colonoscopy; Double-Blind Method; Fema | 2012 |
Pain and distress from bone marrow aspirations and lumbar punctures.
Topics: Adolescent; Anesthetics, Combined; Anesthetics, Intravenous; Anesthetics, Local; Biopsy, Needle; Bon | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy.
Topics: Adult; Aged; Anesthesia; Anesthetics, Intravenous; Anti-Anxiety Agents; Anxiety; Blood Pressure; Fem | 2003 |
Single bolus of midazolam versus bolus midazolam plus meperidine for colonoscopy: a prospective, randomized, double-blind trial.
Topics: Analgesics, Opioid; Colonoscopy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyp | 2003 |
Midazolam syrup as a premedication to reduce the discomfort associated with pediatric intravenous catheter insertion.
Topics: Administration, Oral; Catheterization, Central Venous; Child; Child, Preschool; Double-Blind Method; | 2003 |
Memory in pediatric patients undergoing conscious sedation for aversive medical procedures.
Topics: Adolescent; Amnesia, Retrograde; Anesthetics, Intravenous; Child; Conscious Sedation; Diagnostic Tes | 2003 |
Patient-controlled sedation for colonoscopy: a randomized trial comparing patient-controlled administration of propofol and alfentanil with physician-administered midazolam and pethidine.
Topics: Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Alfentanil; Analgesia, Patient-Controlled; An | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Propofol versus midazolam/fentanyl for outpatient colonoscopy: administration by nurses supervised by endoscopists.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Ambulatory Care; Anesthesia Recovery Period; Attenti | 2003 |
Effect of midazolam on anxiety level and pain perception in cataract surgery with topical anesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Intravenous; Anesthetics, Local; Anxiety; D | 2004 |
A prospective randomized comparison of extensive prostate biopsy to standard biopsy with assessment of diagnostic yield, biopsy pain and morbidity.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Biopsy; Conscious Sedation; Fentanyl; Huma | 2004 |
Intrathecal midazolam II: combination with intrathecal fentanyl for labor pain.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Drug Therapy, Combination; Female; Fentanyl; H | 2004 |
Improving the acceptability of the atrial defibrillator: patient-activated cardioversion versus automatic night cardioversion with and without sedation (ADSAS 2).
Topics: Anxiety; Atrial Fibrillation; Cross-Over Studies; Defibrillators, Implantable; Electric Countershock | 2004 |
The effect of coinduction with midazolam on propofol injection pain.
Topics: Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Midazol | 2004 |
Conscious sedation: Off-label use of rectal S(+)-ketamine and midazolam for wound dressing changes in paediatric heat injuries.
Topics: Adjuvants, Anesthesia; Analgesics; Bandages; Burns; Child; Child, Preschool; Conscious Sedation; Dru | 2004 |
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; | 2004 |
[Comparison of 4 anesthetic techniques for in vitro fertilization].
Topics: Adult; Alfentanil; Anesthesia, General; Anesthesia, Spinal; Anesthetics; Anesthetics, General; Anest | 2005 |
Response entropy increases during painful stimulation.
Topics: Aged; Arousal; Blood Pressure; Brain; Electric Stimulation; Electroencephalography; Electromyography | 2005 |
Propofol versus midazolam/ketamine for procedural sedation in pediatric oncology.
Topics: Adolescent; Anesthetics, Dissociative; Child; Child, Preschool; Conscious Sedation; Humans; Hypnotic | 2005 |
Pain and anxiety during interventional radiologic procedures: effect of patients' state anxiety at baseline and modulation by nonpharmacologic analgesia adjuncts.
Topics: Adaptation, Psychological; Aged; Analgesia, Patient-Controlled; Analysis of Variance; Anesthetics, I | 2005 |
Effect of local anesthesia and intravenous sedation on pain perception and vasovagal reactions during femoral arterial sheath removal after percutaneous coronary intervention.
Topics: Aged; Anesthetics, Local; Angioplasty, Balloon, Coronary; Bradycardia; Cardiovascular Diseases; Cons | 2007 |
A comparison of midazolam and midazolam with remifentanil for patient-controlled sedation during operations on third molars.
Topics: Adolescent; Adult; Anesthesia, Local; Blood Pressure; Conscious Sedation; Cooperative Behavior; Fema | 2007 |
A randomized comparison of nitrous oxide plus hematoma block versus ketamine plus midazolam for emergency department forearm fracture reduction in children.
Topics: Adolescent; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Anxiety Agents; Child; Ch | 2006 |
Etomidate versus midazolam for procedural sedation in pediatric outpatients: a randomized controlled trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Consumer Behavior | 2006 |
Midazolam anesthesia during rigid and flexible cystoscopy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Cystoscopes; Cystoscopy; Femal | 2007 |
Impact of an information video before colonoscopy on patient satisfaction and anxiety - a randomized trial.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anxiety; Audiovisual Aids; Colonoscopy; Con | 2007 |
Entonox as a sedative for bone marrow aspiration and biopsy.
Topics: Analgesics; Anesthesia, Inhalation; Anesthesia, Intravenous; Biopsy, Needle; Bone Marrow Examination | 2008 |
Venous complications after i.v. administration of Diazemuls (diazepam) and Dormicum (midazolam).
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Female; Humans; Injections, Intravenous | 1981 |
Alfentanil for conscious sedation during colonoscopy.
Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia Recovery Period; Blood Pressure; Colonoscopy; | 1995 |
Conscious sedation by rectal administration of midazolam or midazolam plus ketamine as alternatives to general anesthesia for dental treatment of uncooperative children.
Topics: Anesthesia, Dental; Anesthesia, Local; Anesthesia, Rectal; Behavior Therapy; Child; Child Behavior; | 1994 |
A dose-response study of the effects of intravenous midazolam on cold pressor-induced pain.
Topics: Adult; Affect; Cold Temperature; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fent | 1995 |
Efficacy of rectal midazolam for the sedation of preschool children undergoing laceration repair.
Topics: Administration, Rectal; Anxiety; Child, Preschool; Conscious Sedation; Double-Blind Method; Emergenc | 1994 |
Efficacy of intranasal midazolam in facilitating suturing of lacerations in preschool children in the emergency department.
Topics: Administration, Intranasal; Anxiety; Child, Preschool; Conscious Sedation; Double-Blind Method; Huma | 1993 |
[Efficacy of the EMLA cream in the reduction of pain caused by venipuncture in children premedicated with oral midazolam].
Topics: Adjuvants, Anesthesia; Administration, Oral; Anesthetics, Local; Child; Child, Preschool; Drug Combi | 1995 |
Effects of intravenous ketamine, alfentanil, or placebo on pain, pinprick hyperalgesia, and allodynia produced by intradermal capsaicin in human subjects.
Topics: Adult; Alfentanil; Analgesics; Anesthetics, Intravenous; Capsaicin; Cross-Over Studies; Double-Blind | 1995 |
[Comparison of analgesic effect of lidocaine tape versus eutectic mixture of lidocaine and tetracaine during infiltration of local anesthetics before epidural block].
Topics: Administration, Topical; Adult; Anesthesia, Epidural; Anesthesia, Local; Anesthetics, Combined; Anes | 1996 |
Conscious sedation for interventional neuroradiology: a comparison of midazolam and propofol infusion.
Topics: Adult; Anesthetics, Intravenous; Anxiety; Attitude of Health Personnel; Cerebrovascular Disorders; C | 1997 |
Sedation and analgesia for colonoscopy: patient tolerance, pain, and cardiorespiratory parameters.
Topics: Adult; Aged; Analgesia; Analgesics, Opioid; Analysis of Variance; Anesthetics, Combined; Anesthetics | 1997 |
A comparison of three regional anaesthesia techniques for outpatient knee arthroscopy.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Loca | 1997 |
Propofol patient-controlled sedation during hip or knee arthroplasty in elderly patients.
Topics: Adjuvants, Anesthesia; Aged; Anesthesia, Conduction; Anxiety; Arthroplasty; Cognition; Conscious Sed | 1997 |
The value of end-tidal CO2 monitoring when comparing three methods of conscious sedation for children undergoing painful procedures in the emergency department.
Topics: Capnography; Carbon Dioxide; Child; Chlorpromazine; Conscious Sedation; Drug Combinations; Emergency | 1997 |
Haemodynamic responses and population pharmacokinetics of midazolam following administration to ventilated, preterm neonates.
Topics: Analysis of Variance; Anesthetics, Intravenous; Blood Flow Velocity; Blood Pressure; Cerebrovascular | 1997 |
Midazolam versus diazepam in lipid emulsion as conscious sedation for colonoscopy with or without reversal of sedation with flumazenil.
Topics: Adolescent; Adult; Analysis of Variance; Anesthetics, Combined; Anesthetics, Intravenous; Antidotes; | 1998 |
[The effects of midazolam on the memory of pain].
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anti-Anxiety Agents; Female; Humans; Injections, Int | 1998 |
Midazolam-flumazenil versus propofol anaesthesia for scoliosis surgery with wake-up tests.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; An | 1998 |
[Bronchial endoscopy under local anesthesia and pain in children. The value of a nitrous oxide-oxygen combination].
Topics: Adjuvants, Anesthesia; Administration, Rectal; Anesthesia, Local; Anesthetics, Inhalation; Anestheti | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Comparison of fentanyl/midazolam with ketamine/midazolam for pediatric orthopedic emergencies.
Topics: Adolescent; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Anxiety Agents; Anxiety; Child; Chil | 1998 |
Pain following intravenous administration of sedative agents: a comparison of propofol with three benzodiazepines.
Topics: Adult; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Anti-Anxiety Agents; Cros | 1998 |
Subcutaneous administration of midazolam: a comparison of the Bioject jet injector with the conventional syringe and needle.
Topics: Adolescent; Adult; Anesthetics, Local; Double-Blind Method; Equipment Design; Humans; Hypnotics and | 1998 |
Effect of butorphanol tartrate on shock-related discomfort during internal atrial defibrillation.
Topics: Administration, Intranasal; Adult; Aged; Analgesics, Opioid; Atrial Fibrillation; Butorphanol; Doubl | 1999 |
Patients willing to try colonoscopy without sedation: associated clinical factors and results of a randomized controlled trial.
Topics: Analgesics, Opioid; Colonoscopy; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Male; | 1999 |
Midazolam/ketamine sedative combination compared with fentanyl/propofol/isoflurane anaesthesia for oocyte retrieval.
Topics: Adult; Anesthesia, General; Anesthetics; Female; Fentanyl; Humans; Hypnotics and Sedatives; Isoflura | 1999 |
Conscious sedation with remifentanil and midazolam during brief painful procedures in children.
Topics: Analgesics, Opioid; Biopsy; Bone Marrow Examination; Child; Child, Preschool; Conscious Sedation; Dr | 1999 |
A double-blind placebo controlled trial of oral midazolam as premedication before flexible sigmoidoscopy.
Topics: Administration, Oral; Anxiety; Blood Pressure; Double-Blind Method; Female; Humans; Hypnotics and Se | 1999 |
Midazolam nasal spray reduces procedural anxiety in children.
Topics: Administration, Intranasal; Adolescent; Aerosols; Anti-Anxiety Agents; Anxiety; Catheterization, Cen | 2000 |
Sedation with sufentanil and midazolam decreases pain in patients undergoing upper limb surgery under multiple nerve block.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Arm; Conscious Sedation; Double-Blind Met | 2000 |
Technical considerations and patient comfort in total colonoscopy with and without a transparent cap: initial experiences from a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Alfentanil; Anesthesia, Intravenous; Anesthetics, Intravenous; Colon | 2000 |
A randomised controlled trial of intravenous versus inhalational analgesia during outpatient oocyte recovery.
Topics: Administration, Inhalation; Adult; Analgesia; Analgesia, Patient-Controlled; Anesthetics, Inhalation | 2000 |
Midazolam sedation for upper gastrointestinal endoscopy in older persons: a randomized, double-blind, placebo-controlled study.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Anxiety Agents; Conscious Sedation; Double-Blind | 2000 |
A randomized clinical trial of continuous-flow nitrous oxide and midazolam for sedation of young children during laceration repair.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Child; Child, Preschool; Conscious Sedation; Emergen | 2001 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Effect of magnetic endoscope imaging on patient tolerance and sedation requirements during colonoscopy: a randomized controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Colonoscopes; Colonoscopy; Female; Humans; Hypnotics and Sedat | 2002 |
Reducing children's fear when undergoing painful procedures.
Topics: Child; Child, Preschool; Double-Blind Method; Emergency Service, Hospital; Fear; Humans; Infant; Mid | 1992 |
Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Drug Monitoring; England; Female; Hemo | 1992 |
An investigation of the effect of midazolam on the pain experience.
Topics: Adult; Conscious Sedation; Double-Blind Method; Female; Humans; Infusions, Intravenous; Male; Midazo | 1992 |
Midazolam versus fentanyl as premedication for painful procedures in children with cancer.
Topics: Adolescent; Anxiety; Bone Marrow Examination; Child; Child, Preschool; Conscious Sedation; Double-Bl | 1992 |
Self-administration of midazolam for postoperative anxiety: a double blinded study.
Topics: Adult; Aged; Anxiety; Depression; Double-Blind Method; Female; Humans; Midazolam; Middle Aged; Morph | 1992 |
Intravenous midazolam versus fentanyl as premedication for painful procedures in pediatric oncology patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Double-Blind Method; Fentanyl; Humans; Midazolam; Neopla | 1991 |
Midazolam premedication for pediatric bone marrow aspiration and lumbar puncture.
Topics: Adolescent; Anxiety; Biopsy, Needle; Double-Blind Method; Humans; Midazolam; Pain; Pilot Projects; P | 1991 |
Short report: sedation for upper gastrointestinal endoscopy--diazepam versus midazolam.
Topics: Adolescent; Adult; Aged; Diazepam; Endoscopy, Gastrointestinal; Female; Humans; Male; Midazolam; Mid | 1990 |
Pain relief for outpatient colonoscopy: a comparison of alfentanil with fentanyl.
Topics: Adult; Aged; Alfentanil; Colonoscopy; Female; Fentanyl; Follow-Up Studies; Humans; Injections, Intra | 1990 |
Diazepam mixed micelle--comparison with diazepam in propylene glycol and midazolam.
Topics: Benzodiazepines; Blood Pressure; Diazepam; Female; Heart Rate; Humans; Micelles; Midazolam; Pain; Ph | 1985 |
Failure of two benzodiazepines to prevent suxamethonium-induced muscle pain.
Topics: Adolescent; Adult; Analgesics; Benzodiazepines; Diazepam; Double-Blind Method; Female; Humans; Male; | 1985 |
A comparison of midazolam and diazepam for sedation during locoregional anesthesia.
Topics: Adult; Anesthesia, Local; Diazepam; Double-Blind Method; Female; Hemodynamics; Humans; Male; Midazol | 1987 |
Other Studies
162 other studies available for midazolam and Ache
| Article | Year |
|---|---|
Benefits of Intranasal Administration of Diamorphine and Midazolam in the Management of Patients Receiving Palliative Care in the Community: A Case Series.
Topics: Administration, Intranasal; Adult; Child; Heroin; Humans; Midazolam; Pain; Palliative Care | 2022 |
Tracheostomy decreases continuous analgesia and sedation requirements.
Topics: Adult; Aged; Analgesia; Analgesics; Anti-Anxiety Agents; Endrin; Female; Fentanyl; Humans; Hypnotics | 2022 |
Symptom Control and Survival for People Severely ill With COVID: A Multicentre Cohort Study (CovPall-Symptom).
Topics: Aged; Cohort Studies; COVID-19; Delirium; Dyspnea; Humans; Midazolam; Morphine; Pain; Palliative Car | 2022 |
Effect of sedation using Ketamine for primary closure of pediatric facial laceration.
Topics: Child; Conscious Sedation; Facial Injuries; Humans; Hypnotics and Sedatives; Infant; Ketamine; Lacer | 2022 |
The Reversal of Empathy-Induced Hypernociception in Male Mice by Intra-Amygdala Administration of Midazolam and Cannabidiol Depends on 5-HT
Topics: Amygdala; Animals; Cannabidiol; Empathy; Male; Mice; Midazolam; Pain; Serotonin | 2023 |
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud | 2023 |
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud | 2023 |
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud | 2023 |
Hepatic Hilar Nerve Block for Adjunctive Analgesia during Percutaneous Thermal Ablation of Hepatic Tumors: A Retrospective Analysis.
Topics: Aged; Analgesia; Fentanyl; Humans; Liver Neoplasms; Midazolam; Nerve Block; Pain; Retrospective Stud | 2023 |
[Analysis of the effect of midazolam on pain in a rat model of lumbar disc herniation based on the p38 MAPK signaling pathway].
Topics: Animals; Female; Intervertebral Disc Displacement; Male; MAP Kinase Signaling System; Matrix Metallo | 2023 |
Histamine H1 receptor antagonist attenuates catecholamine surge and organ injury after severe burns.
Topics: Animals; Cetirizine; Fentanyl; Histamine; Histamine H1 Antagonists; Midazolam; Pain; Promethazine; R | 2023 |
The association of patient age, race, and demographic features on reported pain and sedation dosing during procedural abortion: A retrospective cohort study.
Topics: Abortion, Induced; Ambulatory Care Facilities; Conscious Sedation; Demography; Female; Fentanyl; Hum | 2023 |
Evaluation of an updated sedation protocol to reduce benzodiazepines in a pediatric intensive care unit.
Topics: Analgesia; Anesthesia; Benzodiazepines; Delirium; Female; Humans; Hypnotics and Sedatives; Infant; I | 2020 |
Premedication practices for tracheal intubation in neonates transported by French medical transport teams: a prospective observational study.
Topics: Analgesics, Opioid; Atropine; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Intub | 2019 |
Feasibility and impact of the implementation of a clinical scale-based sedation-analgesia protocol in severe burn patients undergoing mechanical ventilation. A before-after bi-center study.
Topics: Adult; Analgesics, Opioid; Burns; Clinical Protocols; Controlled Before-After Studies; Dose-Response | 2020 |
Clinical and Economic Evaluation of the Impact of Midazolam on Morphine Therapy for Pain Relief in Critically Ill Ventilated Infants with Respiratory Distress Syndrome.
Topics: Cost-Benefit Analysis; Critical Illness; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; I | 2021 |
Pain medication requirements in patients with opioid use disorder at the time of surgical abortion: An exploratory study.
Topics: Conscious Sedation; Female; Fentanyl; Humans; Hypnotics and Sedatives; Midazolam; Opioid-Related Dis | 2021 |
A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China.
Topics: Delirium; Dexmedetomidine; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Un | 2017 |
A relapsed lower-lip squamous cell carcinoma treated with curative electrochemotherapy in an elderly patient.
Topics: Airway Obstruction; Analgesics, Opioid; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Squamous | 2018 |
[The impact of goal directed analgesia on mechanical ventilated patients's outcomes in intensive care unit: a clinical observational study].
Topics: Analgesia; China; Critical Care; Delirium; Dexmedetomidine; Drug Administration Schedule; Goals; Hum | 2017 |
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Critical Care; Delirium; Dexmedetomidine; Female; Humans; H | 2018 |
Quantification of Pain and Distress Associated With Intranasal Midazolam Administration in Children and Evaluation of Validity of Four Observational Measures.
Topics: Child; Child, Preschool; Humans; Infant; Midazolam; Pain; Pain Measurement; Pilot Projects; Prospect | 2021 |
Can We Replace Midazolam With Massage Therapy in the Pediatric Cardiac ICU?
Topics: Anxiety; Child; Humans; Hypnotics and Sedatives; Intensive Care Units; Massage; Midazolam; Pain; Pil | 2018 |
Procedural sedation and analgesia in the emergency department in Japan: interim analysis of multicenter prospective observational study.
Topics: Aged; Analgesia; Anesthesia; Conscious Sedation; Electric Countershock; Emergency Service, Hospital; | 2019 |
Discussions about palliative sedation in hospice: Frequency, timing and factors associated with patient involvement.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antipsychotic Agents; Decision Making, Shared; Delirium | 2019 |
Evaluation of Tramadol-Midazolam-Ketamine Anaesthesia in Rabbits.
Topics: Anesthetics; Animals; Body Temperature; Heart Rate; Ketamine; Midazolam; Pain; Rabbits; Tramadol; Xy | 2018 |
Comparison of the Effects of Midazolam/Fentanyl, Midazolam/Propofol, and Midazolam/Fentanyl/Propofol on Cognitive Function After Gastrointestinal Endoscopy.
Topics: Analgesics, Opioid; Cognition; Drug Therapy, Combination; Endoscopy, Gastrointestinal; Female; Fenta | 2019 |
Propofol Compared to Midazolam Sedation and to General Anesthesia for Percutaneous Microwave Ablation in Patients with Hepatic Malignancies: A Single-Center Comparative Analysis of Three Historical Cohorts.
Topics: Ablation Techniques; Aged; Anesthesia, General; Cohort Studies; Female; Humans; Hypnotics and Sedati | 2019 |
Midazolam for urethral catheterisation in female infants with suspected urinary tract infection: a case-control study.
Topics: Anesthetics, Intravenous; Bacteria; Case-Control Studies; Emergency Service, Hospital; Female; Human | 2014 |
Premedication for neonatal endotracheal intubation: results from the epidemiology of procedural pain in neonates study.
Topics: Age Factors; Analgesics, Opioid; Evidence-Based Medicine; Guideline Adherence; Humans; Hypnotics and | 2013 |
[Palliative sedation in a man with oral cancer; the Royal Dutch Medical Association guidelines not always sufficient].
Topics: Carcinoma, Squamous Cell; Conscious Sedation; Humans; Hypnotics and Sedatives; Male; Midazolam; Midd | 2013 |
Pre- and post-intervention study to assess the impact of a sedation protocol in critically ill surgical patients.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Critical Care; Critica | 2013 |
Post-sedation events in children sedated for dental care.
Topics: Adjuvants, Anesthesia; Anesthesia, Dental; Child; Child Behavior; Child, Preschool; Conscious Sedati | 2013 |
The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease.
Topics: Administration, Intravenous; Adolescent; Adult; Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; | 2014 |
The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease.
Topics: Administration, Intravenous; Adolescent; Adult; Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; | 2014 |
The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease.
Topics: Administration, Intravenous; Adolescent; Adult; Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; | 2014 |
The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease.
Topics: Administration, Intravenous; Adolescent; Adult; Analgesics; Analgesics, Opioid; Anemia, Sickle Cell; | 2014 |
The use of ancillary techniques to aid colonoscope insertion.
Topics: Ambulatory Care; Colonoscopes; Colonoscopy; Colorectal Neoplasms; Deep Sedation; Female; Humans; Hyp | 2014 |
Safety analysis of endoscopist-directed propofol sedation: a prospective, national multicenter study of 24 441 patients in German outpatient practices.
Topics: Colonoscopy; Conscious Sedation; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 2014 |
Effect of intravenous general anaesthesia with epidural block on the expression of pre-endogenous opioid peptide genes.
Topics: Abdomen; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; beta-Endorphin; | 2014 |
[Is it acceptable in 2014 that three-quarters of newborns are intubated without any sedation in the delivery room?].
Topics: Analgesics; Delivery Rooms; Delivery, Obstetric; Humans; Hypnotics and Sedatives; Infant, Newborn; I | 2014 |
Emergency department procedural sedation: the London experience.
Topics: Academic Medical Centers; Adult; Aged; Analgesia; Cohort Studies; Confidence Intervals; Conscious Se | 2015 |
Analgesic effects of morphine in combination with adjuvant drugs in rats.
Topics: Adjuvants, Pharmaceutic; Analgesics, Opioid; Animals; Butylscopolammonium Bromide; Drug Interactions | 2014 |
Pain and satisfaction during rigid cystoscopic ureteral stent removal: a preliminary study.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Cross-Sectional Studies; Cystoscopy; Device Removal; H | 2014 |
Effect of premedication regimen on infant pain and stress response to endotracheal intubation.
Topics: Analgesics, Opioid; Blood Glucose; Drug Combinations; Fentanyl; Gestational Age; Humans; Infant; Int | 2015 |
Palliative Sedation at the End of Life: Patterns of Use in an Israeli Hospice.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antipsychotic Agents; Female; Haloperidol; Hospices; Hu | 2016 |
Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.
Topics: Analgesia; Animals; Arginine; Benzodiazepines; Diazepam; GABA Modulators; Gene Expression; Histidine | 2015 |
The Efficacy and Safety of Procedural Sedoanalgesia with Midazolam and Ketamine in Pediatric Hematology.
Topics: Adolescent; Analgesia; Analgesics; Bone Marrow Examination; Child; Child, Preschool; Deep Sedation; | 2015 |
GABAA-benzodiazepine receptors in the dorsomedial (Dm) telencephalon modulate restraint-induced antinociception in the fish Leporinus macrocephalus.
Topics: Analysis of Variance; Animals; Fishes; Flumazenil; Formaldehyde; GABA Modulators; Locomotion; Microi | 2015 |
Safety of deep sedation in young children with sickle cell disease: a retrospective cohort study.
Topics: Acute Chest Syndrome; Adjuvants, Anesthesia; Anemia, Sickle Cell; Child; Child, Preschool; Deep Seda | 2015 |
Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy.
Topics: Adult; Aged; Analgesics, Opioid; Brain; Colonoscopy; Conscious Sedation; Female; Humans; Hypnotics a | 2016 |
Comment: "Prospective case control evaluation of epidural midazolam for improving pain and ambulation after microdiscectomy".
Topics: Diskectomy; Humans; Midazolam; Pain; Pain Measurement; Pain, Postoperative; Prospective Studies; Wal | 2016 |
Response to the Comments: "Prospective case control evaluation of epidural midazolam for improving pain and ambulation after microdiscectomy".
Topics: Anesthesia, Epidural; Diskectomy; Humans; Midazolam; Pain; Pain Measurement; Pain, Postoperative; Pr | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Predicting the Best Fit: A Comparison of Response Surface Models for Midazolam and Alfentanil Sedation in Procedures With Varying Stimulation.
Topics: Adult; Alfentanil; Colonoscopy; Consciousness; Decision Support Techniques; Drug Dosage Calculations | 2016 |
Propofol versus midazolam for procedural sedation in the emergency department: A study on efficacy and safety.
Topics: Aged; Aged, 80 and over; Conscious Sedation; Emergency Treatment; Female; Humans; Hypnotics and Seda | 2017 |
[Conscious sedation and amnesic effect of intravenous low-dose midazolam prior to spinal anesthesia].
Topics: Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Conscious Sedation; Humans; Injections, Intraven | 2008 |
Sedation challenge.
Topics: Alfentanil; Anesthesia, Dental; Anti-Anxiety Agents; Conscious Sedation; Dental Anxiety; Humans; Hyp | 2008 |
Adding midazolam to ketamine in the pediatric emergency department--it doesn't add up.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Drug Therapy, Combination; Emergency Medical Se | 2008 |
The antinociceptive effects of midazolam on three different types of nociception in mice.
Topics: Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Hot Temperature; Injections, Int | 2009 |
Ketamine and midazolam in combination.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Bandages; Burns; Drug Therapy, C | 2009 |
Blockade of fear-induced antinociception with intra-amygdala infusion of midazolam: Influence of prior test experience.
Topics: Acetic Acid; Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Catheterization; Dose-Res | 2009 |
[Sedation using ketamine for pain procedures in Pediatric Oncology.].
Topics: Child; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Ketamine; Midazolam; Pain | 2009 |
Emergency sedation in children. Utility of intranasal midazolam.
Topics: Administration, Intranasal; Anesthetics, Local; Child; Conscious Sedation; Emergency Treatment; Huma | 2009 |
The safety of flexible fibre-optic bronchoscopy and proceduralist-administered sedation: a tertiary referral centre experience.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Bronchoscopy; Conscious Sedation; Dyspnea; Femal | 2012 |
Midazolam enhances the analgesic properties of dexmedetomidine in the rat.
Topics: Analgesia; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Hypnotics and | 2010 |
Concentrated midazolam for intranasal administration: a pilot study.
Topics: Administration, Intranasal; Child; Child, Preschool; Conscious Sedation; Dose-Response Relationship, | 2011 |
The contribution of sympathetic mechanisms to postamputation phantom and residual limb pain: a pilot study.
Topics: Adjuvants, Anesthesia; Adult; Aged; Amputation, Surgical; Amputees; Female; Follow-Up Studies; Human | 2011 |
Preemptive analgesic effects of midazolam and diclofenac in rat model.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Models, Animal; Fo | 2011 |
The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation.
Topics: Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Female; Fentanyl; Humans; | 2012 |
Sedation or inhalant anesthesia before euthanasia with CO2 does not reduce behavioral or physiologic signs of pain and stress in mice.
Topics: Acepromazine; Adrenocorticotropic Hormone; Anesthesia; Animal Welfare; Animals; Animals, Laboratory; | 2012 |
Analgesic effects of tramadol in combination with adjuvant drugs: an experimental study in rats.
Topics: Adjuvants, Pharmaceutic; Analgesia; Analgesics; Animals; Anti-Anxiety Agents; Antiemetics; Antipsych | 2013 |
Does "patient-reported discomfort" from bronchoscopy differ over time?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bronchoscopy; Female; Humans; Hypnotics and Sedatives; M | 2012 |
Rescue is stressful.
Topics: Accidents; Anti-Anxiety Agents; Emergencies; Humans; Midazolam; Pain; Transportation of Patients | 2002 |
Role of benzodiazepine and serotonergic mechanisms in conditioned freezing and antinociception using electrical stimulation of the dorsal periaqueductal gray as unconditioned stimulus in rats.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Conditioning, Classical; Dose-Respo | 2002 |
Comparison of colonoscopies performed under sedation with propofol or with midazolam or without sedation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Colonoscopy; Female; Heart Rate; Humans; | 2003 |
MSJAMA. Pain and forgetting.
Topics: Anecdotes as Topic; Conscious Sedation; Humans; Hypnotics and Sedatives; Memory; Midazolam; Pain | 2003 |
General anaesthesia or conscious sedation for painful procedures in childhood cancer: the family's perspective.
Topics: Adolescent; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Intravenous; Biopsy, Needle; B | 2003 |
Spinal carbonic anhydrase contributes to nociceptive reflex enhancement by midazolam, pentobarbital, and propofol.
Topics: Acetazolamide; Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Hypnotics | 2003 |
Correlation of the dose of midazolam for symptom control with administration periods: the possibility of tolerance.
Topics: Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Drug Admini | 2003 |
Midazolam can potentiate the analgesic effects of intrathecal bupivacaine on thermal- or inflammatory-induced pain.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Animals; Behavior, Animal; Bupivacaine; Dose-Response | 2003 |
[Screening colonoscopy among persons 50 to 60 years of age with and without familial risk of colorectal cancer - a prospective multicenter trial].
Topics: Adenoma; Age Factors; Colonoscopy; Colorectal Neoplasms; Confidence Intervals; Female; Humans; Hypno | 2003 |
Pain and sedation.
Topics: Adolescent; Analgesics, Opioid; Cellulitis; Child, Preschool; Contraindications; Emergencies; Facial | 2004 |
Can oral midazolam provide relief of discomfort or analgesia?
Topics: Administration, Oral; Anti-Anxiety Agents; Catheterization, Central Venous; Child; Humans; Hypnotics | 2004 |
Identification of factors that influence conscious sedation in gastrointestinal endoscopy.
Topics: Age Factors; Anesthetics, Intravenous; Body Weight; Conscious Sedation; Endoscopy, Gastrointestinal; | 2004 |
Sedation for terminally ill patients with cancer with uncontrollable physical distress.
Topics: Adult; Aged; Aged, 80 and over; Conscious Sedation; Consciousness; Dose-Response Relationship, Drug; | 2005 |
Concurrent nociceptive stimulation impairs the anxiolytic effect of midazolam injected into the periaqueductal gray in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Behavior, Animal; Disease Models, Animal; | 2005 |
Painful procedures in children with cancer: comparison of moderate sedation and general anesthesia for lumbar puncture and bone marrow aspiration.
Topics: Analgesics, Non-Narcotic; Anesthesia, General; Bone Marrow Examination; Child; Child, Preschool; Con | 2005 |
Diclofenac pretreatment for propofol.
Topics: Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Fentanyl; Humans; Mid | 2005 |
Tracheal intubation in routine practice with and without muscular relaxation: an observational study.
Topics: Adult; Anesthetics, Intravenous; Atracurium; Female; Follow-Up Studies; Humans; Hydroxyzine; Hypnoti | 2005 |
Pain and anxiety: two problems, two solutions.
Topics: Adaptation, Psychological; Analgesia, Patient-Controlled; Anesthetics, Intravenous; Anxiety; Attenti | 2005 |
Pharmacological assessment of the freezing, antinociception, and exploratory behavior organized in the ventrolateral periaqueductal gray.
Topics: Analysis of Variance; Anesthetics, Intravenous; Animals; Behavior, Animal; Dose-Response Relationshi | 2006 |
Effects of initial pain treatment on sedation recovery time in pediatric emergency care.
Topics: Adolescent; Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Child; Child, Preschool; Con | 2006 |
Safe and efficacious use of procedural sedation and analgesia by non-anesthesiologists in a pediatric hematology-oncology unit.
Topics: Adolescent; Analgesics; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studie | 2006 |
[Sedation in children: how and for who?].
Topics: Alfentanil; Anesthesia, General; Child; Conscious Sedation; Contraindications; Cooperative Behavior; | 2006 |
High-dose subcutaneous midazolam infusions in palliative care.
Topics: Humans; Hypnotics and Sedatives; Infusions, Intravenous; Injections, Subcutaneous; Midazolam; Neopla | 1992 |
Analgesic effects of systemic midazolam: comparison with intrathecal administration.
Topics: Analgesics; Animals; Injections, Intraperitoneal; Injections, Intravenous; Injections, Spinal; Male; | 2006 |
Consigning "brutacaine" to history: a survey of pharmacological techniques to facilitate painful procedures in children in emergency departments in the UK.
Topics: Administration, Intranasal; Administration, Topical; Analgesics; Anesthesia, Local; Child; Emergency | 2006 |
The anxiolytic effects of midazolam during anticipation to pain revealed using fMRI.
Topics: Anti-Anxiety Agents; Behavior; Brain; Brain Mapping; Cohort Studies; Color; Diazepam; Humans; Light; | 2007 |
Midazolam-pain, but one cannot remember it: a survey among Southern German endoscopists.
Topics: Clinical Competence; Endoscopy, Gastrointestinal; Germany; Health Care Surveys; Humans; Hypnotics an | 2007 |
[Italian guidelines and recommendations for prevention and treatment of pain in the newborn].
Topics: Adjuvants, Anesthesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Atropine; Drug Therapy, C | 2006 |
Current state of sedation/analgesia care in dentistry.
Topics: Anesthesia, Dental; Conscious Sedation; Dental Anxiety; Dentistry; Dexmedetomidine; Humans; Hypnotic | 2007 |
Practice of palliative sedation in children with brain tumors and sarcomas at the end of life.
Topics: Adolescent; Bone Neoplasms; Brain Neoplasms; Child; Combined Modality Therapy; Consciousness; Glioma | 2007 |
[Treatment of intolerable sufferings in a hospice unit].
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Hospices; Humans; Hypnotics and Sedative | 2007 |
Midazolam potentiates nociceptive behavior, sensitizes cutaneous reflexes, and is devoid of sedative action in neonatal rats.
Topics: Animals; Animals, Newborn; Female; Hypnotics and Sedatives; Male; Midazolam; Pain; Pain Measurement; | 2008 |
Inadequate provision of postintubation anxiolysis and analgesia in the ED.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Cohort Studies; Emergency Service, Ho | 2008 |
Antinociceptive activity of midazolam in sheep.
Topics: Analgesia; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Inj | 1995 |
Difficult management of pain following sacrococcygeal chordoma: 13 months of subarachnoid infusion.
Topics: Bupivacaine; Chordoma; Humans; Injections, Spinal; Male; Midazolam; Middle Aged; Morphine; Pain; Sac | 1994 |
Continuous subarachnoid infusion to control severe cancer pain in an ambulant patient.
Topics: Adenocarcinoma; Adult; Analgesia; Bupivacaine; Humans; Injections, Spinal; Male; Midazolam; Morphine | 1994 |
Conscious sedation of children.
Topics: Anxiety; Child; Conscious Sedation; Emergencies; Fentanyl; Humans; Midazolam; Pain | 1994 |
Intrathecal midazolam reduces isoflurane MAC and increases the apnoeic threshold in rats.
Topics: Anesthesia, Spinal; Animals; Apnea; Blood Pressure; Carbon Dioxide; Dose-Response Relationship, Drug | 1994 |
Drug-induced methemoglobinemia in a healthy 20-year-old soldier undergoing shoulder surgery.
Topics: Adult; Arthroscopy; Fentanyl; Humans; Male; Methemoglobinemia; Methylene Blue; Midazolam; Pain; Prop | 1993 |
[The effects of small dose midazolam in patients to reduce the uncomfortable feeling during epidural block procedure].
Topics: Adult; Aged; Anesthesia, Epidural; Anxiety; Female; Humans; Injections, Intravenous; Male; Midazolam | 1994 |
Midazolam sedation for percutaneous liver biopsy.
Topics: Anesthesia, Intravenous; Biopsy, Needle; Consumer Behavior; Humans; Liver; Memory; Midazolam; Pain; | 1993 |
Midazolam sedation for percutaneous liver biopsy.
Topics: Anesthesia, Intravenous; Biopsy, Needle; Consumer Behavior; Humans; Liver; Memory; Midazolam; Pain; | 1993 |
Midazolam sedation for percutaneous liver biopsy.
Topics: Anesthesia, Intravenous; Biopsy, Needle; Consumer Behavior; Humans; Liver; Memory; Midazolam; Pain; | 1993 |
Midazolam sedation for percutaneous liver biopsy.
Topics: Anesthesia, Intravenous; Biopsy, Needle; Consumer Behavior; Humans; Liver; Memory; Midazolam; Pain; | 1993 |
Midazolam and somatosensory evoked potentials.
Topics: Adult; Electric Stimulation; Evoked Potentials; Evoked Potentials, Somatosensory; Female; Humans; In | 1993 |
Peds pain protocols.
Topics: Child; Conscious Sedation; Drug Combinations; Fentanyl; Humans; Midazolam; Pain; Premedication | 1993 |
Inhibition of morphine-induced tolerance and dependence by a benzodiazepine receptor agonist midazolam in the rat.
Topics: Animals; Drug Tolerance; Male; Midazolam; Morphine; Morphine Dependence; Pain; Rats; Rats, Sprague-D | 1993 |
Methohexital infusion technique for conscious sedation.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Anesthetics, Intravenous; Conscious Sedation; Coopera | 1996 |
Long-term intrathecal administration of midazolam and clonidine.
Topics: Activities of Daily Living; Adolescent; Adult; Analgesics, Non-Narcotic; Clonidine; Female; Humans; | 1996 |
[Conduction anesthesia and analgesia in emergency cases. From pain to its treatment].
Topics: Analgesia; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroidal; Emer | 1995 |
Midazolam impairs the acquisition of conditioned analgesia if rats are tested with an acute but not a chronic noxious stimulus.
Topics: Animals; Conditioning, Psychological; Male; Midazolam; Pain; Pain Measurement; Rats; Rats, Wistar; R | 1996 |
The role of midazolam-induced sedation in bone marrow aspiration/trephine biopsies.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Antidotes; Awareness; Bone Marrow; Conscious Sedation; | 1996 |
[Management of anxious and painful manifestations in pediatric uroradiology].
Topics: Administration, Rectal; Age Factors; Anesthetics, Inhalation; Anti-Anxiety Agents; Anxiety; Child; C | 1997 |
A significant difference is one that makes a difference.
Topics: Anesthetics, Intravenous; Antidotes; Benzodiazepines; Clinical Trials as Topic; Conscious Sedation; | 1997 |
Sedation for procedures.
Topics: Adolescent; Analgesics, Opioid; Child; Child, Preschool; Conscious Sedation; Drug Therapy, Combinati | 1997 |
Attenuation of pain on injection of propofol--an unexpected benefit of co-induction with midazolam.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Humans; Midazolam; Pain; Propofol | 1998 |
Sedation for pediatric procedures, using ketamine and midazolam, in a primarily adult intensive care unit: a retrospective evaluation.
Topics: Adolescent; Adult; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Child | 1998 |
Nasal manipulation with intravenous sedation. Is it an acceptable and effective treatment?
Topics: Administration, Intranasal; Adolescent; Adult; Anesthesia, Local; Anesthetics, Local; Conscious Seda | 1998 |
The use of transcutaneous electrical nerve stimulation during the biliary lithotripsy procedure.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Intravenous; Cholelithiasis; Conscious Sedation; Female; | 1992 |
Analgesic interaction between intrathecal midazolam and glutamate receptor antagonists on thermal-induced pain in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Drug Synergism; Excitatory A | 1999 |
[Pediatricians' opinion on sedation in children].
Topics: Adult; Age Factors; Aged; Anesthesia; Anti-Anxiety Agents; Attitude of Health Personnel; Child; Chlo | 1999 |
Use of intravenous ketamine-midazolam association for pain procedures in children with cancer. A prospective study.
Topics: Adolescent; Analgesics; Biopsy; Biopsy, Needle; Blood Pressure; Catheterization, Central Venous; Chi | 1999 |
Effects of midazolam in the spinal nerve ligation model of neuropathic pain in rats.
Topics: Animals; Cold Temperature; Electrophysiology; Evoked Potentials; Flumazenil; GABA Modulators; Inject | 2000 |
A multicentre international study of sedation for uncontrolled symptoms in terminally ill patients.
Topics: Aged; Analgesics, Opioid; Anti-Anxiety Agents; Consciousness; Delirium; Drug Therapy, Combination; D | 2000 |
Temporary sedation with midazolam for control of severe incident pain.
Topics: Adult; Breast Neoplasms; Female; Humans; Hypnotics and Sedatives; Midazolam; Middle Aged; Osteosarco | 2001 |
The reversal of fentanyl-induced tolerance by administration of "small-dose" ketamine.
Topics: Adult; Analgesics, Opioid; Anesthetics, Dissociative; Drug Therapy, Combination; Drug Tolerance; Fem | 2001 |
Substantial surveillance bias in an unblinded study of pain and adverse effects associated with nitrous oxide inhalation or standard medication for colonoscopy.
Topics: Administration, Inhalation; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; | 2001 |
A comparative study of induction and recovery characteristics of propofol and midazolam.
Topics: Adolescent; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Apnea; Blood Pressure; Femal | 2001 |
The synergistic interaction between midazolam and clonidine in spinally-mediated analgesia in two different pain models of rats.
Topics: Adrenergic alpha-Agonists; Analgesia; Anesthetics, Intravenous; Animals; Behavior, Animal; Clonidine | 2001 |
Topical pharyngeal anesthesia during gastroscopy.
Topics: Anesthesia, Local; Anesthetics, Local; Anxiety; Gastroscopy; Humans; Larynx; Lidocaine; Midazolam; P | 2001 |
A single injection of lidocaine as local anesthesia for ultrasound guided needle biopsy of the prostate.
Topics: Anesthetics, Local; Biopsy, Needle; Humans; Hypnotics and Sedatives; Injections; Lidocaine; Male; Mi | 2002 |
Feasibility of local infiltration anaesthesia for recurrent groin hernia repair.
Topics: Aged; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Bupivacaine; Feasibilit | 2001 |
[Sedation analgesia in interventional radiology].
Topics: Adjuvants, Anesthesia; Alfentanil; Analgesics, Opioid; Anesthetics, Intravenous; Female; Humans; Hyp | 2002 |
[Consciousness during anesthesia for cesarean section].
Topics: Anesthesia, Obstetrical; Anti-Anxiety Agents; Cesarean Section; Consciousness; Female; Humans; Midaz | 1999 |
Patient pain during colonoscopy: an analysis using real-time magnetic endoscope imaging.
Topics: Analgesics; Butylscopolammonium Bromide; Colon; Colon, Sigmoid; Colonoscopy; Drug Combinations; Fema | 2002 |
Can midazolam diminish sufentanil analgesia in patients with major trauma? A retrospective study with 43 patients.
Topics: Adult; Analgesics; Fentanyl; Humans; Midazolam; Pain; Retrospective Studies; Sufentanil; Wounds and | 1992 |
Intrathecal midazolam versus intrathecal morphine in orofacial nociception: an experimental study in rats.
Topics: Animals; Facial Pain; Formaldehyde; Injections, Spinal; Male; Midazolam; Morphine; Mouth; Nociceptor | 1992 |
Sedating patients in intensive care units.
Topics: Critical Care; Humans; Hypnotics and Sedatives; Midazolam; Pain | 1992 |
[The effects of pentazocine, diazepam and midazolam in patients to reduce the uncomfortable feeling during epidural block procedure].
Topics: Adult; Anesthesia, Epidural; Anxiety; Diazepam; Female; Humans; Male; Midazolam; Pain; Pentazocine; | 1992 |
[The antinociceptive effects of fentanyl, midazolam and clonidine and their interactions in the spinal dorsal horn].
Topics: Animals; Cats; Clonidine; Drug Combinations; Drug Synergism; Fentanyl; Injections, Spinal; Male; Mid | 1992 |
Suppressant effects of midazolam on responses of spinal dorsal horn neurones in rabbits.
Topics: Animals; Bradykinin; Decerebrate State; Flunitrazepam; Microelectrodes; Midazolam; Naloxone; Neurons | 1992 |
Midazolam-fentanyl sedation in conjunction with local anesthesia during oocyte retrieval for in vitro fertilization.
Topics: Drug Therapy, Combination; Female; Fentanyl; Fertilization in Vitro; Humans; Injections, Intramuscul | 1992 |
Differential effects of intrathecal midazolam on morphine-induced antinociception in the rat: role of spinal opioid receptors.
Topics: Animals; Binding Sites; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Injecti | 1991 |
Reversal by naloxone of spinal antinociceptive effects of fentanyl, ketocyclazocine and midazolam.
Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Dose-Response Relationship, Drug; Drug Toleranc | 1991 |
Midazolam infusions in critically ill patients.
Topics: Adolescent; Adult; Analgesics, Opioid; Catheterization, Central Venous; Child; Child, Preschool; Con | 1991 |
Benzodiazepines and pain: effects of midazolam on the activities of nociceptive non-specific dorsal horn neurons in the rat spinal cord.
Topics: Analysis of Variance; Animals; Electric Stimulation; Flumazenil; Male; Midazolam; Nerve Fibers; Neur | 1992 |
[Premedication and analgesic dose procedures in dental medicine].
Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazep | 1991 |
On the mechanism by which midazolam causes spinally mediated analgesia.
Topics: Analgesia, Epidural; Animals; Bicuculline; Cyclazocine; Dose-Response Relationship, Drug; Electric S | 1990 |
Intranasal administration of midazolam to a severely burned child.
Topics: Administration, Intranasal; Burns; Child, Preschool; Humans; Male; Midazolam; Pain | 1990 |
A comparison of midazolam with and without nalbuphine for intravenous sedation.
Topics: Adolescent; Adult; Anesthesia, Dental; Consumer Behavior; Drug Combinations; Female; Humans; Injecti | 1990 |
Paralysed with pain: a problem of intensive care organisation.
Topics: Data Collection; Humans; Intensive Care Units; Midazolam; Morphine; Nursing Staff, Hospital; Pain; P | 1990 |
Effects of intrathecal morphine, clonidine, and midazolam on the somato-sympathoadrenal reflex response in halothane-anesthetized cats.
Topics: Adrenal Glands; Anesthesia, Inhalation; Animals; Catecholamines; Cats; Clonidine; Female; Halothane; | 1990 |
Midazolam antagonizes the analgesic effect of morphine in rats.
Topics: Animals; Flumazenil; Male; Midazolam; Morphine; Pain; Rats; Rats, Inbred Strains; Receptors, GABA-A; | 1987 |
Proceedings of the International Symposium on the Uses of Midazolam and Flumazenil in Intensive Care. Saint-Paul-de Vence, France, October 16, 1986.
Topics: Critical Care; Flumazenil; Humans; Midazolam; Pain | 1988 |
RO 15-1788 produces naloxone-reversible analgesia in the rat.
Topics: Analgesics; Animals; Flumazenil; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mi | 1988 |
Conditional analgesia, defensive freezing, and benzodiazepines.
Topics: Animals; Benzodiazepines; Conditioning, Classical; Cytidine Diphosphate; Defense Mechanisms; Diazepa | 1988 |
[Sedation and analgesia in interventions].
Topics: Analgesics; Anesthesia; Child; Child, Preschool; Humans; Leukemia; Midazolam; Pain; Premedication | 1988 |
Myalgia and biochemical changes following intermittent suxamethonium administration. Effects of alcuronium, lignocaine, midazolam and suxamethonium pretreatments on serum myoglobin, creatinine kinase and myalgia.
Topics: Adult; Alcuronium; Creatine Kinase; Female; Humans; Lidocaine; Midazolam; Muscular Diseases; Myoglob | 1987 |
[Midazolam (Dormicum) for sedation of children in painful interventions].
Topics: Arousal; Biopsy, Needle; Bone Marrow; Child; Child, Preschool; Dose-Response Relationship, Drug; Hum | 1987 |