midazolam has been researched along with Abdominal Pain in 11 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol was titrated to a level of deep sedation and propofol combined with midazolam was used for moderate sedation." | 2.74 | CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial. ( Akan, B; Dirlea, D; Karner-Hanusch, J; Mikola, B; Mittlböck, M; Rieder, E; Riss, S; Weiser, FA, 2009) |
| "Preoperatively, 95% of the patients received morphine versus 100% postoperatively, with a median dosage of 10." | 1.43 | Infants Operated on for Necrotizing Enterocolitis: Towards Evidence-Based Pain Guidelines. ( Keyzer-Dekker, CM; Knibbe, CA; Meesters, NJ; Simons, SH; Tibboel, D; van Dijk, M, 2016) |
| "Meperidine and midazolam were most commonly used." | 1.37 | Ileoscopy via stoma after diverting ileostomy: a safe and effective tool to evaluate for Crohn's recurrence of neoterminal ileum. ( Alkhouri, N; Lopez, R; Mahajan, L; Shen, B; Vadlamudi, N, 2011) |
| " Extrapyramidal side effects like tardive dyskinesia are known to develop with chronic use of metoclopramide, while acute akathisia is a lesser known side effect following IV administration." | 1.37 | Case of acute akathisia from intravenous metoclopramide. ( Lim, BL; Qiu, LM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ball, AJ | 1 |
| Rees, CJ | 1 |
| Corfe, BM | 1 |
| Riley, SA | 2 |
| Meesters, NJ | 1 |
| van Dijk, M | 1 |
| Knibbe, CA | 1 |
| Keyzer-Dekker, CM | 1 |
| Tibboel, D | 1 |
| Simons, SH | 1 |
| Cadoni, S | 1 |
| Falt, P | 1 |
| Gallittu, P | 1 |
| Liggi, M | 1 |
| Smajstrla, V | 1 |
| Leung, FW | 1 |
| Elphick, DA | 1 |
| Donnelly, MT | 1 |
| Smith, KS | 1 |
| Riss, S | 1 |
| Akan, B | 1 |
| Mikola, B | 1 |
| Rieder, E | 1 |
| Karner-Hanusch, J | 1 |
| Dirlea, D | 1 |
| Mittlböck, M | 1 |
| Weiser, FA | 1 |
| Vadlamudi, N | 1 |
| Alkhouri, N | 1 |
| Mahajan, L | 1 |
| Lopez, R | 1 |
| Shen, B | 1 |
| Qiu, LM | 1 |
| Lim, BL | 1 |
| Pineau, BC | 1 |
| Vining, DJ | 1 |
| Iyilikci, L | 1 |
| Akarsu, M | 1 |
| Kocaayan, E | 1 |
| Topalak, O | 1 |
| Cacho, G | 1 |
| Dueñas, C | 1 |
| Pérez de las Vacas, J | 1 |
| Robledo, P | 1 |
| Rosado, JL | 1 |
| Fazel, A | 1 |
| Burton, FR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Carbon Dioxide Insufflation and Water Exchange on Post-Colonoscopy Outcomes: A Randomized Controlled Trial[NCT02409979] | 246 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant[NCT04541667] | 200 participants (Actual) | Interventional | 2019-11-18 | Completed | |||
| Water Exchange Versus Carbon Dioxide Insufflation to Improve Colonoscopy Screening - a Randomized Controlled Trial[NCT01633333] | 473 participants (Actual) | Interventional | 2012-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pain rating scales using FLACC and VAS will be used to assess self reported pain before and after the procedure (NCT04541667)
Timeframe: This will be assessed before and after the procedure
| Intervention | participants (Number) |
|---|---|
| Air for Luminal Inflation | 14 |
| Carbon Dioxide for Luminal Inflation | 15 |
Compare the peak end-tidal CO2 levels (>/= 60 mmHg) observed during endoscopy in children managed with endotracheal intubation or laryngeal mask airway using CO2 versus air (NCT04541667)
Timeframe: Measured from time of procedure start to time of procedure conclusion this lasts usually from 1-2.5 hours.
| Intervention | Procedures (Count of Units) |
|---|---|
| Air for Luminal Inflation | 8 |
| Carbon Dioxide for Luminal Inflation | 21 |
3 trials available for midazolam and Abdominal Pain
| Article | Year |
|---|---|
Impact of carbon dioxide insufflation and water exchange on postcolonoscopy outcomes in patients receiving on-demand sedation: a randomized controlled trial.
Topics: Abdominal Pain; Aged; Air; Carbon Dioxide; Colonoscopy; Conscious Sedation; Fecal Incontinence; Fema | 2017 |
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal | 2009 |
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal | 2009 |
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal | 2009 |
CO2 insufflation during colonoscopy decreases post-interventional pain in deeply sedated patients: a randomized controlled trial.
Topics: Abdominal Pain; Adult; Anti-Anxiety Agents; Body Mass Index; Carbon Dioxide; Colonoscopy; Colorectal | 2009 |
[Viability of colonoscopy without analgesia and conscious sedation].
Topics: Abdominal Pain; Adjuvants, Anesthesia; Analgesia; Anesthesia, Intravenous; Colonoscopy; Conscious Se | 2000 |
8 other studies available for midazolam and Abdominal Pain
| Article | Year |
|---|---|
Sedation practice and comfort during colonoscopy: lessons learnt from a national screening programme.
Topics: Abdominal Pain; Administration, Intravenous; Aged; Analgesics, Opioid; Anesthetics, Combined; Colono | 2015 |
Infants Operated on for Necrotizing Enterocolitis: Towards Evidence-Based Pain Guidelines.
Topics: Abdominal Pain; Analgesics, Opioid; Birth Weight; Enterocolitis, Necrotizing; Female; Fentanyl; Gest | 2016 |
Factors associated with abdominal discomfort during colonoscopy: a prospective analysis.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Analgesia; Clinical Competence; Colonoscopy; Female; | 2009 |
Ileoscopy via stoma after diverting ileostomy: a safe and effective tool to evaluate for Crohn's recurrence of neoterminal ileum.
Topics: Abdominal Pain; Adolescent; Adult; Anesthetics, Intravenous; Crohn Disease; Endoscopy, Gastrointesti | 2011 |
Case of acute akathisia from intravenous metoclopramide.
Topics: Abdominal Pain; Adult; Akathisia, Drug-Induced; Diphenhydramine; Emergency Service, Hospital; Female | 2011 |
Better tolerance for colonoscopy or intolerance to virtual colonoscopy?
Topics: Abdominal Pain; Colonic Neoplasms; Colonoscopy; Humans; Hypnotics and Sedatives; Insufflation; Mass | 2002 |
Sedation for endoscopic retrograde cholangiopancreatography (ERCP) in a pregnant patient.
Topics: Abdominal Pain; Adult; Anesthesia; Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Re | 2007 |
The effect of midazolam on the normal sphincter of Oddi: a controlled study.
Topics: Abdominal Pain; Adult; Case-Control Studies; Cholangiopancreatography, Endoscopic Retrograde; Consci | 2002 |