midazolam has been researched along with AIDS Seroconversion in 3 studies
Midazolam: A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.
midazolam : An imidazobenzodiazepine that is 4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted by a methyl, 2-fluorophenyl and chloro groups at positions 1, 6 and 8, respectively.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomalik-Scharte, D | 2 |
| Doroshyenko, O | 2 |
| Kirchheiner, J | 1 |
| Jetter, A | 2 |
| Lazar, A | 1 |
| Klaassen, T | 1 |
| Frank, D | 2 |
| Wyen, C | 1 |
| Fätkenheuer, G | 1 |
| Fuhr, U | 2 |
| Lütjohann, D | 1 |
| Rab-Khan, A | 1 |
| MacLeod, D | 1 |
| Prichard, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cholesterol and CYP3A4/5 Metabolism Across Pregnancy and Postpartum[NCT05504889] | 36 participants (Actual) | Observational | 2022-06-17 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for midazolam and AIDS Seroconversion
| Article | Year |
|---|---|
No role for the CYP3A5*3 polymorphism in intestinal and hepatic metabolism of midazolam.
Topics: Administration, Oral; Adult; Biological Availability; Case-Control Studies; Cytochrome P-450 CYP3A; | 2008 |
Plasma 4beta-hydroxycholesterol: an endogenous CYP3A metric?
Topics: Administration, Oral; Adult; Benzilates; Cholesterol; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzym | 2009 |
Marked increase in benzodiazepine requirements during bronchoscopy in HIV positive intravenous drug abusers.
Topics: Adult; Bronchoscopy; Conscious Sedation; HIV Seropositivity; Humans; Midazolam; Substance Abuse, Int | 1992 |