miconazole has been researched along with Vaginosis, Bacterial in 8 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Vaginosis, Bacterial: Polymicrobial, nonspecific vaginitis associated with positive cultures of Gardnerella vaginalis and other anaerobic organisms and a decrease in lactobacilli. It remains unclear whether the initial pathogenic event is caused by the growth of anaerobes or a primary decrease in lactobacilli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this European multicenter, double-blind PRISM trial, participating women presenting with infectious vaginitis were randomized to receive one vaginal capsule containing either NNP for 12 days or miconazole for 3 days followed by 9 days of placebo." | 9.30 | PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis. ( Aubin, F; Bohbot, JM; Coatantiec, E; Goubard, A; Lucas, N; Mas, Y; Verrière, F, 2019) |
| "In this European multicenter, double-blind PRISM trial, participating women presenting with infectious vaginitis were randomized to receive one vaginal capsule containing either NNP for 12 days or miconazole for 3 days followed by 9 days of placebo." | 5.30 | PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis. ( Aubin, F; Bohbot, JM; Coatantiec, E; Goubard, A; Lucas, N; Mas, Y; Verrière, F, 2019) |
| "To evaluate the efficacy of Neo-Penotran pessaries (metronidazole 500 mg + miconazole nitrate 100 mg) in candidal, bacterial and trichomonal vaginitis and in mixed vaginal infections." | 5.09 | Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections. ( Baktir, G; Danilyans, IL; Morton, O; Ozyurt, E; Toykuliyeva, MB, 2001) |
| " For this reason, the present study was conducted to investigate the effectiveness of octenidine dihydrochloride/phenoxyethanol (OHP) in comparison to antimicrobial therapies in pregnant women in hospital suffering from different types of vaginitis." | 3.81 | Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women. ( Novakov Mikić, A; Stojic, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bohbot, JM | 1 |
| Goubard, A | 1 |
| Aubin, F | 1 |
| Mas, Y | 1 |
| Coatantiec, E | 1 |
| Lucas, N | 1 |
| Verrière, F | 1 |
| Aguin, TJ | 1 |
| Akins, RA | 1 |
| Sobel, JD | 1 |
| McClelland, RS | 2 |
| Balkus, JE | 3 |
| Lee, J | 2 |
| Anzala, O | 3 |
| Kimani, J | 3 |
| Schwebke, J | 3 |
| Bragg, V | 1 |
| Lensing, S | 1 |
| Kavak, L | 1 |
| Novakov Mikić, A | 1 |
| Stojic, S | 1 |
| Manhart, LE | 1 |
| Shafi, J | 1 |
| Rivers, C | 1 |
| Kabare, E | 1 |
| Scott McClelland, R | 1 |
| Srinivasan, S | 1 |
| Andac, C | 1 |
| Fredricks, DN | 1 |
| Kükner, S | 1 |
| Ergin, T | 1 |
| Ciçek, N | 1 |
| Uğur, M | 1 |
| Yeşilyurt, H | 1 |
| Gökmen, O | 1 |
| Ozyurt, E | 1 |
| Toykuliyeva, MB | 1 |
| Danilyans, IL | 1 |
| Morton, O | 1 |
| Baktir, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis[NCT02185456] | Early Phase 1 | 200 participants (Anticipated) | Interventional | 2014-09-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for miconazole and Vaginosis, Bacterial
| Article | Year |
|---|---|
PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis.
Topics: Adolescent; Adult; Arsenicals; Candidiasis, Vulvovaginal; Double-Blind Method; Drug Combinations; Dr | 2019 |
High-dose vaginal metronidazole for recurrent bacterial vaginosis--a pilot study.
Topics: Adult; Anti-Infective Agents; Female; Humans; Metronidazole; Miconazole; Pilot Projects; Recurrence; | 2014 |
Randomized Trial of Periodic Presumptive Treatment With High-Dose Intravaginal Metronidazole and Miconazole to Prevent Vaginal Infections in HIV-negative Women.
Topics: Adolescent; Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Chemoprevention; Female; Humans | 2015 |
Periodic Presumptive Treatment for Vaginal Infections May Reduce the Incidence of Sexually Transmitted Bacterial Infections.
Topics: Adult; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Drug Therapy, Combination | 2016 |
Impact of Periodic Presumptive Treatment for Bacterial Vaginosis on the Vaginal Microbiome among Women Participating in the Preventing Vaginal Infections Trial.
Topics: Actinobacteria; Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Dose-Response Rel | 2017 |
Treatment of vaginitis.
Topics: Adult; Antifungal Agents; Antitrichomonal Agents; Candidiasis, Vulvovaginal; Female; Humans; Metroni | 1996 |
Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections.
Topics: Administration, Intravaginal; Adolescent; Adult; Antifungal Agents; Antitrichomonal Agents; Candidia | 2001 |
1 other study available for miconazole and Vaginosis, Bacterial
| Article | Year |
|---|---|
Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women.
Topics: Adolescent; Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Ethylene Glycols; Female; Human | 2015 |