miconazole has been researched along with Vaginitis in 22 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Vaginitis: Inflammation of the vagina characterized by pain and a purulent discharge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this European multicenter, double-blind PRISM trial, participating women presenting with infectious vaginitis were randomized to receive one vaginal capsule containing either NNP for 12 days or miconazole for 3 days followed by 9 days of placebo." | 9.30 | PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis. ( Aubin, F; Bohbot, JM; Coatantiec, E; Goubard, A; Lucas, N; Mas, Y; Verrière, F, 2019) |
| "In this European multicenter, double-blind PRISM trial, participating women presenting with infectious vaginitis were randomized to receive one vaginal capsule containing either NNP for 12 days or miconazole for 3 days followed by 9 days of placebo." | 5.30 | PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis. ( Aubin, F; Bohbot, JM; Coatantiec, E; Goubard, A; Lucas, N; Mas, Y; Verrière, F, 2019) |
| "To evaluate the efficacy of Neo-Penotran pessaries (metronidazole 500 mg + miconazole nitrate 100 mg) in candidal, bacterial and trichomonal vaginitis and in mixed vaginal infections." | 5.09 | Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections. ( Baktir, G; Danilyans, IL; Morton, O; Ozyurt, E; Toykuliyeva, MB, 2001) |
| " For this reason, the present study was conducted to investigate the effectiveness of octenidine dihydrochloride/phenoxyethanol (OHP) in comparison to antimicrobial therapies in pregnant women in hospital suffering from different types of vaginitis." | 3.81 | Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women. ( Novakov Mikić, A; Stojic, S, 2015) |
| "The dermatopharmacokinetic method determined the bioequivalence of two products simultaneously in 24 healthy subjects, as a function of Cmax and AUC(0-1) parameters using miconazole nitrate content in harvested volar forearm stratum corneum." | 2.70 | Comparison of dermatopharmacokinetic vs. clinicial efficacy methods for bioequivalence assessment of miconazole nitrate vaginal cream, 2% in humans. ( Corlett, JL; Nelson, JL; Pershing, LK, 2002) |
| " In the present work, we aim at the development of a novel miconazole (MCZ) microsponges gel as an attractive dosage form for vaginal candidiasis." | 1.48 | Improved vaginal retention and enhanced antifungal activity of miconazole microsponges gel: Formulation development and in vivo therapeutic efficacy in rats. ( Awad, GEA; Makhlouf, AIA; Salah, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Wit, K | 1 |
| Paulussen, C | 1 |
| Matheeussen, A | 1 |
| van Rossem, K | 1 |
| Cos, P | 1 |
| Maes, L | 1 |
| Salah, S | 1 |
| Awad, GEA | 1 |
| Makhlouf, AIA | 1 |
| Bohbot, JM | 1 |
| Goubard, A | 1 |
| Aubin, F | 1 |
| Mas, Y | 1 |
| Coatantiec, E | 1 |
| Lucas, N | 1 |
| Verrière, F | 1 |
| Novakov Mikić, A | 1 |
| Stojic, S | 1 |
| Hubert, T | 1 |
| Van Bulck, B | 1 |
| Van Waes, A | 1 |
| Van de Velde, E | 1 |
| Van der Pas, H | 1 |
| Lambin, A | 1 |
| de Louvois, J | 1 |
| Obolensky, W | 1 |
| Simon, U | 1 |
| Nisselle, P | 1 |
| Drake, SM | 1 |
| Evans, BA | 1 |
| Gerken, A | 1 |
| Asikoglu, M | 1 |
| Ertan, G | 1 |
| Ercan, MT | 1 |
| Duman, Y | 1 |
| Thirion, DJ | 1 |
| Zanetti, LA | 1 |
| Ozyurt, E | 1 |
| Toykuliyeva, MB | 1 |
| Danilyans, IL | 1 |
| Morton, O | 1 |
| Baktir, G | 1 |
| Pershing, LK | 1 |
| Corlett, JL | 1 |
| Nelson, JL | 1 |
| Shturkalev, I | 1 |
| Karat'ozov, I | 1 |
| Traianova, E | 1 |
| Stoilov, L | 1 |
| Hantschke, D | 1 |
| Zabel, M | 1 |
| Dame, WR | 1 |
| Fegeler, W | 1 |
| Donini, G | 1 |
| Balbi, F | 1 |
| Giulini, N | 1 |
| Josey, WE | 1 |
| Baumann, RJ | 1 |
| Mayer, GD | 1 |
| Fite, LD | 1 |
| Gill, LM | 1 |
| Harrison, BL | 1 |
| Landers, DV | 1 |
| Koetsawang, A | 1 |
| Koetsawang, S | 1 |
| Nukulkarn, P | 1 |
| Jirojkul, V | 1 |
| Blanc, B | 1 |
1 review available for miconazole and Vaginitis
| Article | Year |
|---|---|
The treatment of vaginitis: Trichomonas, yeast, and bacterial vaginosis.
Topics: Antifungal Agents; Bacterial Infections; Candidiasis, Vulvovaginal; Clotrimazole; Drug Administratio | 1988 |
6 trials available for miconazole and Vaginitis
| Article | Year |
|---|---|
PRISM study: Comparison of a nystatin-neomycin-polymyxin B combination with miconazole for the empirical treatment of infectious vaginitis.
Topics: Adolescent; Adult; Arsenicals; Candidiasis, Vulvovaginal; Double-Blind Method; Drug Combinations; Dr | 2019 |
Vaginal pH and microflora related to yeast infections and treatment.
Topics: Adolescent; Adult; Female; Humans; Hydrogen-Ion Concentration; Lactobacillus; Menstruation; Miconazo | 1980 |
Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections.
Topics: Administration, Intravaginal; Adolescent; Adult; Antifungal Agents; Antitrichomonal Agents; Candidia | 2001 |
Comparison of dermatopharmacokinetic vs. clinicial efficacy methods for bioequivalence assessment of miconazole nitrate vaginal cream, 2% in humans.
Topics: Adult; Analysis of Variance; Candida albicans; Candidiasis, Vulvovaginal; Confidence Intervals; Fema | 2002 |
[Results of treating vaginal mycosis with the new antimycotic preparation, Gyno-Daktarin (miconazole)].
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Imidazoles; Miconazole; Middle Age | 1977 |
Randomized comparative study on the treatment of vaginal mycosis by single dose of isoconazole and multiple dose of nystatin.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Miconazole; Middle Aged; Mycoses; Nystatin; Random | 1986 |
15 other studies available for miconazole and Vaginitis
| Article | Year |
|---|---|
In vitro profiling of pramiconazole and in vivo evaluation in Microsporum canis dermatitis and Candida albicans vaginitis laboratory models.
Topics: Administration, Topical; Animals; Antifungal Agents; Candida albicans; Dermatitis; Female; Guinea Pi | 2010 |
Improved vaginal retention and enhanced antifungal activity of miconazole microsponges gel: Formulation development and in vivo therapeutic efficacy in rats.
Topics: Animals; Antifungal Agents; Contraceptive Devices, Female; Drug Carriers; Drug Compounding; Drug Del | 2018 |
Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women.
Topics: Adolescent; Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Ethylene Glycols; Female; Human | 2015 |
Efficacy and tolerance of local treatment of acute vulvovaginal candidiasis with 4 different single doses (10, 25, 50 and 100 mg) of Ro 14-4767 versus a 7-day treatment with miconazole.
Topics: Antifungal Agents; Candidiasis; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Adm | 1989 |
Activity of miconazole against Streptococcus agalactiae.
Topics: Female; Humans; Imidazoles; Miconazole; Microbial Sensitivity Tests; Streptococcus agalactiae; Vagin | 1980 |
[Diagnosis and therapy of vulvovaginal mycosis (author's transl)].
Topics: Adult; Antifungal Agents; Bacteriological Techniques; Candidiasis, Vulvovaginal; Econazole; Female; | 1981 |
The management of vaginal discharges.
Topics: Bacterial Infections; Candidiasis, Vulvovaginal; Female; Humans; Metronidazole; Miconazole; Nystatin | 1980 |
The release of isoconazole nitrate from different suppository bases: in-vivo release of drug labelled with 99mTc in rabbits.
Topics: Animals; Antifungal Agents; Delayed-Action Preparations; Disease Models, Animal; Drug Delivery Syste | 1995 |
Potentiation of warfarin's hypoprothrombinemic effect with miconazole vaginal suppositories.
Topics: Administration, Intravaginal; Anticoagulants; Antifungal Agents; Drug Synergism; Ecchymosis; Female; | 2000 |
[The reaction of the physiological vaginal flora to topical antimycotics (author's transl)].
Topics: Antifungal Agents; Bacteria; Candida; Candida albicans; Candidiasis, Vulvovaginal; Clotrimazole; Fem | 1979 |
[Experiences with an antimycotic tampon in the treatment of saccharomycetic vaginal infection].
Topics: Adolescent; Adult; Evaluation Studies as Topic; Female; Humans; Imidazoles; Miconazole; Middle Aged; | 1979 |
[Personal experience with ITF 1117 in vaginitis, especially in that caused by Candida albicans].
Topics: Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Female; Humans; Imidazoles; Miconazole; Middle Ag | 1978 |
Vaginitis. Reducing the number of refractory cases.
Topics: Ampicillin; Candidiasis, Vulvovaginal; Contraception; Corynebacterium Infections; Female; Humans; Me | 1977 |
In vitro and in vivo candicidal activities of 2-(p-n-hexylphenylamino)-1,3-thiazoline.
Topics: Administration, Topical; Animals; Candida albicans; Candidiasis, Vulvovaginal; Clotrimazole; Colony | 1991 |
[Effectiveness of 400 mg miconazole pellets in various types of vaginitis].
Topics: Administration, Topical; Adult; Bacterial Infections; Candidiasis, Vulvovaginal; Capsules; Female; H | 1985 |