miconazole and Urinary Bladder Neoplasms
miconazole has been researched along with Urinary Bladder Neoplasms in 3 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"We demonstrate in this study that miconazole dramatically increases NRF2 activation in bladder cancer cells, in a dose- and time-dependent manner." | 7.96 | Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells. ( Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2020) |
"Miconazole (MIC), an antifungal agent, diplays anti‑tumorigenic activity in various types of human cancers, including bladder cancer, yet its mechanism of antitumor action is not well understood." | 7.85 | Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells. ( Chen, CC; Cheng, CL; Chiu, KY; Huang, YC; Ou, YC; Shiau, MY; Tsai, KJ; Wang, SS; Yuan, SY, 2017) |
"Miconazole was found to exert antitumor effects in various tumors, including bladder cancer (BC)." | 5.62 | Miconazole induces protective autophagy in bladder cancer cells. ( Chang, AC; Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hsu, CH; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2021) |
"We demonstrate in this study that miconazole dramatically increases NRF2 activation in bladder cancer cells, in a dose- and time-dependent manner." | 3.96 | Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells. ( Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2020) |
"Miconazole (MIC), an antifungal agent, diplays anti‑tumorigenic activity in various types of human cancers, including bladder cancer, yet its mechanism of antitumor action is not well understood." | 3.85 | Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells. ( Chen, CC; Cheng, CL; Chiu, KY; Huang, YC; Ou, YC; Shiau, MY; Tsai, KJ; Wang, SS; Yuan, SY, 2017) |
"Miconazole was found to exert antitumor effects in various tumors, including bladder cancer (BC)." | 1.62 | Miconazole induces protective autophagy in bladder cancer cells. ( Chang, AC; Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hsu, CH; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2021) |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 2 (66.67) | 2.80 |
Authors
Authors | Studies |
---|---|
Tsai, TF | 2 |
Chen, PC | 2 |
Lin, YC | 2 |
Chou, KY | 2 |
Chen, HE | 2 |
Ho, CY | 2 |
Lin, JF | 2 |
Hwang, TI | 2 |
Chang, AC | 1 |
Hsu, CH | 1 |
Yuan, SY | 1 |
Shiau, MY | 1 |
Ou, YC | 1 |
Huang, YC | 1 |
Chen, CC | 1 |
Cheng, CL | 1 |
Chiu, KY | 1 |
Wang, SS | 1 |
Tsai, KJ | 1 |
Other Studies
3 other studies available for miconazole and Urinary Bladder Neoplasms
Article | Year |
---|---|
Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells.
Topics: Dose-Response Relationship, Drug; Humans; Kelch-Like ECH-Associated Protein 1; Miconazole; NF-E2-Rel | 2020 |
Miconazole induces protective autophagy in bladder cancer cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Lysosomes; Macrolides; Miconazole; Mi | 2021 |
Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Gene Expression Regu | 2017 |