Page last updated: 2024-10-31

miconazole and Urinary Bladder Neoplasms

miconazole has been researched along with Urinary Bladder Neoplasms in 3 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.

Research Excerpts

ExcerptRelevanceReference
"We demonstrate in this study that miconazole dramatically increases NRF2 activation in bladder cancer cells, in a dose- and time-dependent manner."7.96Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells. ( Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2020)
"Miconazole (MIC), an antifungal agent, diplays anti‑tumorigenic activity in various types of human cancers, including bladder cancer, yet its mechanism of antitumor action is not well understood."7.85Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells. ( Chen, CC; Cheng, CL; Chiu, KY; Huang, YC; Ou, YC; Shiau, MY; Tsai, KJ; Wang, SS; Yuan, SY, 2017)
"Miconazole was found to exert antitumor effects in various tumors, including bladder cancer (BC)."5.62Miconazole induces protective autophagy in bladder cancer cells. ( Chang, AC; Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hsu, CH; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2021)
"We demonstrate in this study that miconazole dramatically increases NRF2 activation in bladder cancer cells, in a dose- and time-dependent manner."3.96Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells. ( Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2020)
"Miconazole (MIC), an antifungal agent, diplays anti‑tumorigenic activity in various types of human cancers, including bladder cancer, yet its mechanism of antitumor action is not well understood."3.85Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells. ( Chen, CC; Cheng, CL; Chiu, KY; Huang, YC; Ou, YC; Shiau, MY; Tsai, KJ; Wang, SS; Yuan, SY, 2017)
"Miconazole was found to exert antitumor effects in various tumors, including bladder cancer (BC)."1.62Miconazole induces protective autophagy in bladder cancer cells. ( Chang, AC; Chen, HE; Chen, PC; Chou, KY; Ho, CY; Hsu, CH; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Tsai, TF2
Chen, PC2
Lin, YC2
Chou, KY2
Chen, HE2
Ho, CY2
Lin, JF2
Hwang, TI2
Chang, AC1
Hsu, CH1
Yuan, SY1
Shiau, MY1
Ou, YC1
Huang, YC1
Chen, CC1
Cheng, CL1
Chiu, KY1
Wang, SS1
Tsai, KJ1

Other Studies

3 other studies available for miconazole and Urinary Bladder Neoplasms

ArticleYear
Miconazole Contributes to NRF2 Activation by Noncanonical P62-KEAP1 Pathway in Bladder Cancer Cells.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Dose-Response Relationship, Drug; Humans; Kelch-Like ECH-Associated Protein 1; Miconazole; NF-E2-Rel

2020
Miconazole induces protective autophagy in bladder cancer cells.
    Environmental toxicology, 2021, Volume: 36, Issue:2

    Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Humans; Lysosomes; Macrolides; Miconazole; Mi

2021
Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells.
    Oncology reports, 2017, Volume: 37, Issue:6

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Gene Expression Regu

2017
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