Page last updated: 2024-10-31

miconazole and Recrudescence

miconazole has been researched along with Recrudescence in 38 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Research Excerpts

ExcerptRelevanceReference
"The objective of this 2-year, double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence."9.11Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%. ( St Clair, KR; Warshaw, EM, 2005)
"A topical preparation containing miconazole, polymyxin and prednisolone was shown to be more effective in the treatment of otitis externa in 167 dogs than 2 other ear preparations containing antibiotics, an antimycotic and a corticosteroid."9.07A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs. ( Hughes, KL; Studdert, VP, 1991)
"In 3 controlled multi-center studies, 372 patients suffering from dermatomycoses were treated with isoconazole as cream, solution, and spray either once or twice daily."9.06[Once daily administration of isoconazole as a cream, solution and spray: comparative studies of patients with dermatomycoses]. ( Herms, E; Kallischnigg, G, 1988)
"Miconazole was injected intravenously in six patients with coccidioidomycosis."7.66Treatment of coccidioidomycosis with miconazole. ( Goldstein, E; Hoeprich, PD; Lawrence, RM, 1980)
"Two patients with second relapses of pulmonary blastomycosis after successful treatments with adequate doses of amphotericin B were retreated with miconazole."7.66Miconazole treatment of relapsed pulmonary blastomycosis. ( Rose, HD; Varkey, B, 1978)
"Intravenous miconazole, an investigational, broad-spectrum, antifungal imidazole drug, was clinically effective when used for the first time in a patient with life-threatening sporotrichosis."7.65Pulmonary sporotrichosis: Treatment with miconazole. ( Archer, G; Rohwedder, JJ, 1976)
"Consequently, favus is still an important health problem encountered in Turkey."5.42[A recurrent case of adult favus successfully treated with terbinafine]. ( Acar, A; Erkan, D; İlkit, M; Kandemir, H; Kolukırık, İ, 2015)
"The objective of this 2-year, double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence."5.11Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%. ( St Clair, KR; Warshaw, EM, 2005)
"A topical preparation containing miconazole, polymyxin and prednisolone was shown to be more effective in the treatment of otitis externa in 167 dogs than 2 other ear preparations containing antibiotics, an antimycotic and a corticosteroid."5.07A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs. ( Hughes, KL; Studdert, VP, 1991)
"In 3 controlled multi-center studies, 372 patients suffering from dermatomycoses were treated with isoconazole as cream, solution, and spray either once or twice daily."5.06[Once daily administration of isoconazole as a cream, solution and spray: comparative studies of patients with dermatomycoses]. ( Herms, E; Kallischnigg, G, 1988)
"Miconazole was injected intravenously in six patients with coccidioidomycosis."3.66Treatment of coccidioidomycosis with miconazole. ( Goldstein, E; Hoeprich, PD; Lawrence, RM, 1980)
"Two patients with second relapses of pulmonary blastomycosis after successful treatments with adequate doses of amphotericin B were retreated with miconazole."3.66Miconazole treatment of relapsed pulmonary blastomycosis. ( Rose, HD; Varkey, B, 1978)
"Intravenous miconazole, an investigational, broad-spectrum, antifungal imidazole drug, was clinically effective when used for the first time in a patient with life-threatening sporotrichosis."3.65Pulmonary sporotrichosis: Treatment with miconazole. ( Archer, G; Rohwedder, JJ, 1976)
"Miconazole is an antifungal drug against certain types of fungus or yeast infections."3.11Efficacy and safety of miconazole muco-adhesive tablet versus itraconazole in oropharyngeal candidiasis: A randomized, multi-centered, double-blind, phase 3 trial. ( Chai, H; Chen, Q; Duan, N; Fan, Y; Fei, W; Guan, X; Hua, H; Jia, C; Jiang, L; Kong, H; Liu, J; Liu, Q; Lu, H; Lun, W; Luo, Z; Shen, X; Tang, G; Wang, H; Wang, W; Wang, Y; Xu, J; Yan, Z; Zhang, T; Zhao, J; Zhou, H, 2022)
"The incidences of recurrence/reinfection and treatment failures were comparable in the two groups."2.65A comparison of the efficacy of two vaginal creams for vulvovaginal candidiasis, and correlations with the presence of Candida species in the perianal area and oral contraceptive use. ( Ford, LC; Goldman, L; Lebherz, TB; Mason, D; Wiesmeier, E, 1983)
"The high rate of recurrence of this condition is noted and the need for at least 6 months' follow-up in future trials of candidacides is emphasized."2.65Vulvovaginal candidiasis: treatment and recurrence. ( Dennerstein, GJ; Langley, R, 1982)
"Miconazole was used as sucking tablets in the treatment of oral candidosis in 11 patients in whom other antimycotics had been without effect for at least a preceding 3-month period."2.64Miconazole in the treatment of oral candidosis. ( Roed-Petersen, B, 1978)
"Miconazole has been commonly used when treating oral candidiasis."2.55Treatment and Prevention of Oral Candidiasis in Elderly Patients. ( Sakaguchi, H, 2017)
"The therapy of coccidioidomycosis has been an early target, both experimentally and clinically, for study of new members of the azole class of drugs, because of the recognition that coccidioidomycosis is one of the most difficult mycoses to treat, and because our research group and our collaborators have been eager to pioneer new therapies for this problem pathogen."2.44Azole therapy of clinical and experimental coccidioidomycosis. ( Clemons, KV; Stevens, DA, 2007)
"Consequently, favus is still an important health problem encountered in Turkey."1.42[A recurrent case of adult favus successfully treated with terbinafine]. ( Acar, A; Erkan, D; İlkit, M; Kandemir, H; Kolukırık, İ, 2015)
" All patients found the single dosage formulation easy to use, and the majority thought the ovule effective as a treatment for their vaginal candidosis."1.28An open study to assess the acceptability and effectiveness of miconazole 1,200 mg single ovule in the treatment of acute vaginal candidosis. ( Dinsmore, WW; Granger, SE, 1989)
"The miconazole tampons were highly acceptable to patients."1.26Comparison of miconazole-coated tampons with clotrimazole vaginal tablets in the treatment of vaginal candidosis. ( Balsdon, MJ, 1981)
"Successful treatment of fungal endocarditis is being described with increasing frequency."1.26Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported. ( Galgiani, JN; Stevens, DA, 1977)
"Miconazole nitrate was significantly more effective than nystatin (Mycostatin) in the treatment of vaginal candidiasis in all three trimesters of pregnancy, and also more effective regardless of whether the candidal infection was primary or recurrent."1.26Treatment of vulvovaginal candidiasis in pregnancy. A comparative study. ( Lawson, J; McLeod, M; McNellis, D; Pasquale, SA, 1977)
"Retreatment in three cases of recurrence was successful."1.26Gynodaktarin (miconazole nitrate) for vulvovaginal candidiasis. ( Rutherford, AM, 1976)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199024 (63.16)18.7374
1990's6 (15.79)18.2507
2000's3 (7.89)29.6817
2010's4 (10.53)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Wang, Y1
Zhou, H1
Wang, W2
Duan, N1
Luo, Z1
Chai, H1
Jiang, L1
Chen, Q1
Liu, J1
Hua, H1
Yan, Z1
Fan, Y1
Xu, J1
Guan, X1
Wang, H1
Lu, H1
Lun, W1
Fei, W1
Zhang, T1
Zhao, J1
Jia, C1
Kong, H1
Shen, X1
Liu, Q1
Tang, G1
Sakaguchi, H1
Xie, HY1
Feng, D1
Wei, DM1
Mei, L1
Chen, H1
Wang, X1
Fang, F1
Aguin, TJ1
Akins, RA1
Sobel, JD1
Erkan, D1
Kolukırık, İ1
Acar, A1
Kandemir, H1
İlkit, M1
Mårdh, PA1
Wågström, J1
Landgren, M1
Holmén, J1
Warshaw, EM1
St Clair, KR1
Stevens, DA3
Clemons, KV1
Puolakka, J1
Tuimala, R1
Lebherz, TB1
Goldman, L1
Wiesmeier, E1
Mason, D1
Ford, LC1
Tanenbaum, L1
Anderson, C1
Rosenberg, MJ1
Howard, W1
McDaniel, W1
Neimanis, A1
Ryan, ME1
Perez, R1
Opsomer, R1
Claus, D1
Cosijns, JP1
Gigi, J1
Cornu, G1
Hennebert, P1
Dennerstein, GJ1
Langley, R1
Nisselle, P1
Balsdon, MJ2
Hoeprich, PD1
Lawrence, RM1
Goldstein, E1
Chubachi, A1
Miura, I1
Ohshima, A1
Nishinari, T1
Nimura, T1
Niitsu, H1
Miura, AB1
Bourrain, JL1
Béani, JC1
Amblard, P1
Roed-Petersen, B1
Eliot, BW1
Howat, RC1
Mack, AE1
Deresinski, SC1
Rose, HD1
Varkey, B1
Wallenburg, HC1
Wladimiroff, JW1
Galgiani, JN1
Stevens, D1
McNellis, D1
McLeod, M1
Lawson, J1
Pasquale, SA1
Rohwedder, JJ1
Archer, G1
Rutherford, AM1
Bell, A1
Sharma, JB1
Buckshee, K1
Gulati, N1
Studdert, VP1
Hughes, KL1
Corson, SL1
Kapikian, RR1
Nehring, R1
Dinsmore, WW1
Granger, SE1
Herms, E1
Kallischnigg, G1
Senff, H1
Bothe, C1
Riemann, U1
Reinel, D1
Tobin, JM1
Ansari, RA1
Hindson, DA1
Stevens, DL1
Kloss, JG1
Cohen, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Validation of a Novel Diagnostic, Prognostic Assay for Bacterial Vaginosis[NCT02185456]Early Phase 1200 participants (Anticipated)Interventional2014-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for miconazole and Recrudescence

ArticleYear
Treatment and Prevention of Oral Candidiasis in Elderly Patients.
    Medical mycology journal, 2017, Volume: 58, Issue:2

    Topics: Aged; Aged, 80 and over; Antifungal Agents; Candidiasis, Oral; Drug Therapy, Combination; Female; Hu

2017
Probiotics for vulvovaginal candidiasis in non-pregnant women.
    The Cochrane database of systematic reviews, 2017, 11-23, Volume: 11

    Topics: Administration, Intravaginal; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Female; Fl

2017
Azole therapy of clinical and experimental coccidioidomycosis.
    Annals of the New York Academy of Sciences, 2007, Volume: 1111

    Topics: Administration, Oral; Animals; Antifungal Agents; Azoles; Coccidioidomycosis; Disease Models, Animal

2007

Trials

15 trials available for miconazole and Recrudescence

ArticleYear
Efficacy and safety of miconazole muco-adhesive tablet versus itraconazole in oropharyngeal candidiasis: A randomized, multi-centered, double-blind, phase 3 trial.
    Medical mycology, 2022, Nov-03, Volume: 60, Issue:11

    Topics: Adhesives; Antifungal Agents; Candidiasis, Oral; Double-Blind Method; Female; Itraconazole; Male; Mi

2022
High-dose vaginal metronidazole for recurrent bacterial vaginosis--a pilot study.
    Journal of lower genital tract disease, 2014, Volume: 18, Issue:2

    Topics: Adult; Anti-Infective Agents; Female; Humans; Metronidazole; Miconazole; Pilot Projects; Recurrence;

2014
Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:4

    Topics: Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Miconazole; Mid

2005
Comparison between oral ketoconazole and topical miconazole in the treatment of vaginal candidiasis.
    Acta obstetricia et gynecologica Scandinavica, 1983, Volume: 62, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Candidiasis, Vulvovaginal; Clinica

1983
A comparison of the efficacy of two vaginal creams for vulvovaginal candidiasis, and correlations with the presence of Candida species in the perianal area and oral contraceptive use.
    Clinical therapeutics, 1983, Volume: 5, Issue:4

    Topics: Adult; Aged; Candida; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole; Contracepti

1983
Sulconazole nitrate 1.0 percent cream: a comparison with miconazole in the treatment of tinea pedis and tinea cruris/corporis.
    Cutis, 1982, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Imidazoles; Male;

1982
Vulvovaginal candidiasis: treatment and recurrence.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1982, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Child; Clotrimazole; Econazole; Fem

1982
Miconazole in the treatment of oral candidosis.
    International journal of oral surgery, 1978, Volume: 7, Issue:6

    Topics: Administration, Oral; Adult; Aged; Candidiasis, Oral; Clinical Trials as Topic; Drug Evaluation; Fem

1978
A comparison between the effects of nystatin, clotrimazole and miconazole on vaginal candidiasis.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:7

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Evaluation Studies as Topic; Female; Hum

1979
Recurrence of vulvovaginal candidosis during pregnancy. Comparison of miconazole vs nystatin treatment.
    Obstetrics and gynecology, 1976, Volume: 48, Issue:4

    Topics: Adult; Candida; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Drug Evaluation; Female; Humans

1976
A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs.
    Australian veterinary journal, 1991, Volume: 68, Issue:9

    Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Hypersensitivity; Miconazole; Otitis Externa;

1991
A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs.
    Australian veterinary journal, 1991, Volume: 68, Issue:6

    Topics: Administration, Topical; Animals; Betamethasone; Disulfiram; Dog Diseases; Dogs; Drug Combinations;

1991
Terconazole and miconazole cream for treating vulvovaginal candidiasis. A comparison.
    The Journal of reproductive medicine, 1991, Volume: 36, Issue:8

    Topics: Administration, Intravaginal; Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Doubl

1991
[Once daily administration of isoconazole as a cream, solution and spray: comparative studies of patients with dermatomycoses].
    Zeitschrift fur Hautkrankheiten, 1988, May-15, Volume: 63, Issue:5

    Topics: Clinical Trials as Topic; Dermatomycoses; Dosage Forms; Drug Administration Schedule; Humans; Micona

1988
Is more than one application of an antifungal necessary in the treatment of acute vaginal candidiasis?
    American journal of obstetrics and gynecology, 1985, Aug-01, Volume: 152, Issue:7 Pt 2

    Topics: Amphotericin B; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Clotrimazole

1985

Other Studies

20 other studies available for miconazole and Recrudescence

ArticleYear
[A recurrent case of adult favus successfully treated with terbinafine].
    Mikrobiyoloji bulteni, 2015, Volume: 49, Issue:4

    Topics: Antifungal Agents; Drug Therapy, Combination; Female; Hair Follicle; Humans; Ketoconazole; Miconazol

2015
Usage of antifungal drugs for therapy of genital Candida infections, purchased as over-the-counter products or by prescription: I. Analyses of a unique database.
    Infectious diseases in obstetrics and gynecology, 2004, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Databases as Topic; D

2004
[Cortical abscess of the kidney due to Torulopsis glabrata in an 8-month-old child].
    Acta urologica Belgica, 1982, Volume: 50, Issue:3

    Topics: Abscess; Candida; Female; Humans; Infant; Kidney Cortex; Miconazole; Mycoses; Radiography; Recurrenc

1982
The management of vaginal discharges.
    Australian family physician, 1980, Volume: 9, Issue:12

    Topics: Bacterial Infections; Candidiasis, Vulvovaginal; Female; Humans; Metronidazole; Miconazole; Nystatin

1980
Comparison of miconazole-coated tampons with clotrimazole vaginal tablets in the treatment of vaginal candidosis.
    The British journal of venereal diseases, 1981, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Imidazoles; Miconazole;

1981
Treatment of coccidioidomycosis with miconazole.
    JAMA, 1980, May-16, Volume: 243, Issue:19

    Topics: Adult; Amphotericin B; Coccidioidomycosis; Drug Evaluation; Drug Therapy, Combination; Female; Human

1980
Risk factors for hepatosplenic abscesses in patients with acute leukemia receiving empiric azole treatment.
    The American journal of the medical sciences, 1994, Volume: 308, Issue:6

    Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Candidiasis; Female; Fever; Fluconazole; Humans; Le

1994
[Candida vasculitis].
    Allergie et immunologie, 1995, Volume: 27, Issue:10

    Topics: Amphotericin B; Antifungal Agents; Antigens, Fungal; Candida; Candidiasis, Oral; Humans; Male; Micon

1995
Bone and joint coccidioidomycosis treated with miconazole.
    The American review of respiratory disease, 1979, Volume: 120, Issue:5

    Topics: Adolescent; Adult; Aged; Arthritis; Bone Diseases; Child; Chronic Disease; Coccidioidomycosis; Femal

1979
Miconazole treatment of relapsed pulmonary blastomycosis.
    The American review of respiratory disease, 1978, Volume: 118, Issue:2

    Topics: Amphotericin B; Blastomycosis; Drug Evaluation; Follow-Up Studies; Gallium Radioisotopes; Humans; Im

1978
Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported.
    The Journal of thoracic and cardiovascular surgery, 1977, Volume: 73, Issue:2

    Topics: Adult; Amphotericin B; Aortic Valve Stenosis; Candidiasis; Cytosine; Endocarditis; Flucytosine; Hear

1977
Miconazole in the treatment of systemic fungal infections.
    The American review of respiratory disease, 1977, Volume: 116, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Coccidioidomycosis; Drug Resistance, Microbial; Humans; Imidazoles;

1977
Treatment of vulvovaginal candidiasis in pregnancy. A comparative study.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:6

    Topics: Acute Disease; Candidiasis, Vulvovaginal; Female; Fetus; Humans; Imidazoles; Infant, Newborn; Male;

1977
Pulmonary sporotrichosis: Treatment with miconazole.
    The American review of respiratory disease, 1976, Volume: 114, Issue:2

    Topics: Amphotericin B; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combinat

1976
Gynodaktarin (miconazole nitrate) for vulvovaginal candidiasis.
    The New Zealand medical journal, 1976, Jul-14, Volume: 84, Issue:567

    Topics: Candidiasis, Vulvovaginal; Female; Humans; Imidazoles; Miconazole; Pregnancy; Pregnancy Complication

1976
Oral ketoconazole and miconazole vaginal pessary treatment for vaginal candidosis.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1991, Volume: 31, Issue:3

    Topics: Administration, Oral; Adult; Candidiasis, Vulvovaginal; Drug Therapy, Combination; Female; Follow-Up

1991
An open study to assess the acceptability and effectiveness of miconazole 1,200 mg single ovule in the treatment of acute vaginal candidosis.
    The British journal of clinical practice, 1989, Volume: 43, Issue:7

    Topics: Administration, Intravaginal; Adolescent; Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Female;

1989
[Local therapy of pityriasis versicolor with 3 imidazole derivatives--results of a therapeutic study. Studies of the rate of recurrence].
    Zeitschrift fur Hautkrankheiten, 1988, Dec-15, Volume: 63, Issue:12

    Topics: Administration, Topical; Adult; Clotrimazole; Econazole; Follow-Up Studies; Humans; Imidazoles; Male

1988
Recurrent vaginal candidosis: prospective study of effectiveness of maintenance miconazole treatment.
    Genitourinary medicine, 1988, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Female; Humans; Miconazole; Middle Aged; Prospective S

1988
Pseudallescheria boydii arthritis and osteomyelitis in a patient with Cushing's disease.
    Southern medical journal, 1987, Volume: 80, Issue:1

    Topics: Adrenalectomy; Arthritis, Infectious; Combined Modality Therapy; Cushing Syndrome; Humans; Ketoconaz

1987