Page last updated: 2024-10-31

miconazole and Pregnancy

miconazole has been researched along with Pregnancy in 40 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" For this reason, the present study was conducted to investigate the effectiveness of octenidine dihydrochloride/phenoxyethanol (OHP) in comparison to antimicrobial therapies in pregnant women in hospital suffering from different types of vaginitis."3.81Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women. ( Novakov Mikić, A; Stojic, S, 2015)
"Miconazole nitrate was administered once daily, at bedtime, for 14 days to 55 pregnant and non-pregnant patients."2.64Monistat cream (miconazole nitrate) a new agent for the treatment of vulvovaginal candidiasis. ( Cooper, C; Qualey, JR, 1975)
"Various agents are available for the treatment of vulvovaginal candidiasis."2.38Drugs for treatment of vulvovaginal candidiasis: comparative efficacy of agents and regimens. ( Doering, PL; Santiago, TM, 1990)
" For developmental toxicity this requires scaling the in vitro observed dose-response characteristics to in vivo fetal exposure, while integrating maternal in vivo kinetics during pregnancy, in particular transplacental transfer."1.72Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach. ( Fragki, S; Hoogenveen, R; Piersma, AH; Schwillens, P; van Oostrom, C; Zeilmaker, MJ, 2022)
" Furthermore, no association was found between categories of dosage of vaginal antimycotics and spontaneous abortions."1.48Vaginal antimycotics and the risk for spontaneous abortions. ( Daniel, S; Koren, G; Levy, A; Lunenfeld, E; Rotem, R, 2018)
"Cutaneous candidiasis is a disease that affects children as well as adults."1.38[Generalized cutaneous candidiasis in newborn at term]. ( Cañadas-De la Fuente, GA; Cantero-Hinojosa, J; El Ahmed, HH; Fernández-Castillo, R; González-Jiménez, E; Lardón-Fernández, M, 2012)
"Diabetes and pregnancy are two independent factors believed to be responsible for an increased risk of mycoses."1.35[Evaluation of susceptibility to antifungal agents of fungal strains isolated from pregnant women with diabetes and healthy pregnant women]. ( Gaj, Z; Nowakowska, D; Sobala, W; Wilczyński, J, 2009)
"Miconazole was a relatively poor inhibitor of the cholesterol side chain cleavage activity of a placental mitochondria-enriched fraction, while both clotrimazole and ketoconazole markedly inhibited this mitochondrial monooxygenase activity."1.27Imidazole antimycotics: inhibitors of steroid aromatase. ( Mason, JI; Murry, BA; Olcott, M; Sheets, JJ, 1985)
"Miconazole nitrate was significantly more effective than nystatin (Mycostatin) in the treatment of vaginal candidiasis in all three trimesters of pregnancy, and also more effective regardless of whether the candidal infection was primary or recurrent."1.26Treatment of vulvovaginal candidiasis in pregnancy. A comparative study. ( Lawson, J; McLeod, M; McNellis, D; Pasquale, SA, 1977)
"Retreatment in three cases of recurrence was successful."1.26Gynodaktarin (miconazole nitrate) for vulvovaginal candidiasis. ( Rutherford, AM, 1976)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199027 (67.50)18.7374
1990's2 (5.00)18.2507
2000's6 (15.00)29.6817
2010's3 (7.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Fragki, S1
Hoogenveen, R1
van Oostrom, C1
Schwillens, P1
Piersma, AH1
Zeilmaker, MJ1
Lijuan, D1
Lu, Y1
Liping, W1
Yaya, S1
Xiaoyun, L1
Xiangrong, LI1
Daniel, S1
Rotem, R1
Koren, G1
Lunenfeld, E1
Levy, A1
Novakov Mikić, A1
Stojic, S1
Nowakowska, D1
Gaj, Z1
Sobala, W1
Wilczyński, J1
El Ahmed, HH1
Cañadas-De la Fuente, GA1
Fernández-Castillo, R1
González-Jiménez, E1
Cantero-Hinojosa, J1
Lardón-Fernández, M1
Nalbanski, B1
Tsekova, K1
Ivanov, S1
Czeizel, AE2
Kazy, Z2
Puhó, E2
Gauwerky, J1
Schmidt, W1
Kühn, H1
Kubli, F1
Lebherz, TB1
Ford, LC1
Obolensky, W1
Simon, U1
Callaerts, J1
Peeters, F1
Maes-Dockx, F1
Wesel, S1
Bafort, P1
Patrono, D1
Bonomo, A1
Painvain, E1
Di Muccio, L1
Wajnberg, M1
Wajnberg, A1
Fernández Martínez, N1
Gómez Centeno, P1
González Conde, MV1
Martínez Soto, MI1
Couce Pico, ML1
Fernández Lorenzo, JR1
Worster, AA1
Lillich, JD1
Cox, JH1
Rush, BR1
Vapinov, B1
Tsankova, M1
Velev, R1
Georgiev, S1
Brundin, J1
Drutz, DJ1
Catanzaro, A1
Pasquale, SA2
Lawson, J2
Sargent, EC1
Newdeck, JP1
Eliot, BW1
Howat, RC1
Mack, AE1
Vlassis, G1
Zissis, NP1
Kyrou, A1
Papaloukas, A1
Turner, GM1
Qualey, JR1
Cooper, C1
Wallenburg, HC1
Wladimiroff, JW1
McNellis, D1
McLeod, M1
Rutherford, AM1
Hauser, GA1
Tapia, JE1
Doering, PL1
Santiago, TM1
Sasaki, J1
Yamamoto, T2
Okada, H2
Blum, M1
Schweitzer, A1
Ainsworth, RE1
Urabe, M1
Hagler, L1
Brett, L1
Peak, VJ1
Amerson, AB1
Weisberg, M1
Chaland, G1
Bouygues, D1
Mason, JI1
Murry, BA1
Olcott, M1
Sheets, JJ1

Reviews

3 reviews available for miconazole and Pregnancy

ArticleYear
Effectiveness of redcore lotion in patients with vulvovaginal candidiasis: a systematic review and Meta-analysis.
    Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2022, Volume: 42, Issue:4

    Topics: Candidiasis, Vulvovaginal; Female; Humans; Miconazole; Pregnancy; Treatment Outcome

2022
Coccidioidomycosis. Part II.
    The American review of respiratory disease, 1978, Volume: 117, Issue:4

    Topics: Amphotericin B; Arthritis, Infectious; Coccidioidomycosis; Eosinophilia; Erythema; Erythema Multifor

1978
Drugs for treatment of vulvovaginal candidiasis: comparative efficacy of agents and regimens.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:11

    Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Costs and Cost Analysis; Female; Humans;

1990

Trials

9 trials available for miconazole and Pregnancy

ArticleYear
Candida albicans vaginitis: the problem is diagnosis, the enigma is treatment.
    Chemotherapy, 1982, Volume: 28 Suppl 1

    Topics: Candida albicans; Candidiasis, Vulvovaginal; Clotrimazole; Double-Blind Method; Female; Humans; Imid

1982
[A comparative double blind trial with vaginal creams of cyclopyroxolamine and miconazole in vulvovaginal candidosis (author's transl)].
    Mykosen, 1981, Volume: 24, Issue:12

    Topics: Adult; Candidiasis, Vulvovaginal; Ciclopirox; Double-Blind Method; Female; Humans; Imidazoles; Micon

1981
[Klion D - possibilities of prophylaxis and treatment during pregnancy].
    Akusherstvo i ginekologiia, 2001, Volume: 40, Issue:4

    Topics: Administration, Intravaginal; Animals; Anti-Infective Agents; Cerclage, Cervical; Drug Therapy, Comb

2001
The effect of miconazole on vulvo-vaginal candidosis in pregnant and non-pregnant women and their partners.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1976, Volume: 14, Issue:6

    Topics: Balanitis; Candidiasis; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Female; Humans; Imidazo

1976
A dose-response study with Monistat cream.
    Obstetrics and gynecology, 1979, Volume: 53, Issue:2

    Topics: Candidiasis, Vulvovaginal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; H

1979
A comparison between the effects of nystatin, clotrimazole and miconazole on vaginal candidiasis.
    British journal of obstetrics and gynaecology, 1979, Volume: 86, Issue:7

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clotrimazole; Evaluation Studies as Topic; Female; Hum

1979
Monistat cream (miconazole nitrate) a new agent for the treatment of vulvovaginal candidiasis.
    The Journal of reproductive medicine, 1975, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Drug Evaluation; Female; Hum

1975
Recurrence of vulvovaginal candidosis during pregnancy. Comparison of miconazole vs nystatin treatment.
    Obstetrics and gynecology, 1976, Volume: 48, Issue:4

    Topics: Adult; Candida; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Drug Evaluation; Female; Humans

1976
[Frequency and therapy possibilities of soor vaginitis (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1975, Volume: 32, Issue:9

    Topics: Candidiasis, Vulvovaginal; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Miconazole; Pr

1975

Other Studies

28 other studies available for miconazole and Pregnancy

ArticleYear
Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach.
    Toxicology, 2022, 01-15, Volume: 465

    Topics: Animals; Biological Transport; Biomarkers; Caproates; Cell Line; Dose-Response Relationship, Drug; F

2022
Vaginal antimycotics and the risk for spontaneous abortions.
    American journal of obstetrics and gynecology, 2018, Volume: 218, Issue:6

    Topics: Abortion, Spontaneous; Administration, Intravaginal; Adult; Antifungal Agents; Candidiasis, Vulvovag

2018
Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women.
    Archives of gynecology and obstetrics, 2015, Volume: 292, Issue:2

    Topics: Adolescent; Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Ethylene Glycols; Female; Human

2015
[Evaluation of susceptibility to antifungal agents of fungal strains isolated from pregnant women with diabetes and healthy pregnant women].
    Ginekologia polska, 2009, Volume: 80, Issue:4

    Topics: Adult; Antifungal Agents; Candida; Diabetes Complications; Diabetes Mellitus, Type 2; Dose-Response

2009
[Generalized cutaneous candidiasis in newborn at term].
    Biomedica : revista del Instituto Nacional de Salud, 2012, Volume: 32, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Anti-Infective Agents; Bacteremia; Bicarbonates; Ca

2012
[Candidiasis and birth canal injuries].
    Akusherstvo i ginekologiia, 2002, Volume: 41, Issue:6

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Cervix Uteri; Episiotomy; Female; Humans; Micon

2002
Population-based case-control teratologic study of topical miconazole.
    Congenital anomalies, 2004, Volume: 44, Issue:1

    Topics: Abnormalities, Drug-Induced; Administration, Topical; Adult; Antifungal Agents; Case-Control Studies

2004
Effect of vaginal metronidazole + miconazole treatment during pregnancy for gestational age and birth weight in a population-based study.
    Archives of gynecology and obstetrics, 2005, Volume: 272, Issue:4

    Topics: Administration, Intravaginal; Adult; Antifungal Agents; Birth Weight; Case-Control Studies; Female;

2005
Miconazole.
    The Australian nurses' journal. Royal Australian Nursing Federation, 1983, Volume: 12, Issue:8

    Topics: Adult; Candidiasis, Vulvovaginal; Child; Female; Humans; Imidazoles; Miconazole; Pregnancy

1983
[Premature fetal membrane rupture: report of a case of severe intrauterine fungal infection].
    Geburtshilfe und Frauenheilkunde, 1983, Volume: 43, Issue:3

    Topics: Adult; Amniocentesis; Amniotic Fluid; Candidiasis; Candidiasis, Cutaneous; Female; Fetal Diseases; F

1983
[Diagnosis and therapy of vulvovaginal mycosis (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1981, Volume: 38, Issue:10

    Topics: Adult; Antifungal Agents; Bacteriological Techniques; Candidiasis, Vulvovaginal; Econazole; Female;

1981
A shortened regime for the treatment of vulvovaginal candidosis with a new presentation of miconazole.
    European journal of obstetrics, gynecology, and reproductive biology, 1980, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Capsules; Female; Humans; Imidazoles; Miconazole; Midd

1980
[Mycoses in obstetrical and gynecological pathology. The use of miconazole in new preparations in the local therapy of mycotic vaginitis].
    Minerva ginecologica, 1981, Volume: 33, Issue:9

    Topics: Administration, Topical; Adult; Candidiasis, Vulvovaginal; Capsules; Female; Genital Diseases, Femal

1981
[Congenital cutaneous candidiasis. Apropos of 2 cases].
    Anales espanoles de pediatria, 1999, Volume: 51, Issue:3

    Topics: Administration, Topical; Adult; Antifungal Agents; Candidiasis, Cutaneous; Candidiasis, Vulvovaginal

1999
Pythiosis with bone lesions in a pregnant mare.
    Journal of the American Veterinary Medical Association, 2000, Jun-01, Volume: 216, Issue:11

    Topics: Animals; Antifungal Agents; Bone Diseases; Female; Horse Diseases; Horses; Miconazole; Pregnancy; Pr

2000
Cure stability with miconazole in vaginal candidiasis.
    Acta clinica Belgica, 1977, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Female; Follow-Up Studies; Humans; Im

1977
Primary treatment for vaginal candidiasis in obstetric and gynaecological practice.
    The British journal of clinical practice, 1978, Volume: 32, Issue:5

    Topics: Adult; Candidiasis, Vulvovaginal; Female; Humans; Miconazole; Pregnancy; Pregnancy Complications, In

1978
Treatment of vulvovaginal candidiasis in pregnancy. A comparative study.
    Obstetrics and gynecology, 1977, Volume: 50, Issue:6

    Topics: Acute Disease; Candidiasis, Vulvovaginal; Female; Fetus; Humans; Imidazoles; Infant, Newborn; Male;

1977
Gynodaktarin (miconazole nitrate) for vulvovaginal candidiasis.
    The New Zealand medical journal, 1976, Jul-14, Volume: 84, Issue:567

    Topics: Candidiasis, Vulvovaginal; Female; Humans; Imidazoles; Miconazole; Pregnancy; Pregnancy Complication

1976
[The synergistic abortive effect of anti-progestogen RU 38486 and aromatase inhibitors for pregnant rat].
    Nihon Sanka Fujinka Gakkai zasshi, 1989, Volume: 41, Issue:2

    Topics: Abortifacient Agents; Abortifacient Agents, Steroidal; Aminoglutethimide; Animals; Aromatase; Estren

1989
[Advantages of single-dose treatment of vaginal Candida albicans infection].
    Revue francaise de gynecologie et d'obstetrique, 1989, Volume: 84, Issue:1

    Topics: Adult; Candidiasis, Vulvovaginal; Female; Humans; Miconazole; Middle Aged; Pregnancy; Pregnancy Comp

1989
Use and safety of miconazole during pregnancy.
    The Western journal of medicine, 1987, Volume: 147, Issue:5

    Topics: Female; Fetus; Humans; Miconazole; Pregnancy; Pregnancy Complications, Infectious; Risk Factors

1987
[The inhibitory effect of miconazole on aromatase activity for androstenedione in human placental and ovarian preparations].
    Nihon Naibunpi Gakkai zasshi, 1987, Nov-20, Volume: 63, Issue:11

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; In Vitro Techniques; Micon

1987
"Treatment of vaginal candidiasis in pregnant women,".
    Clinical therapeutics, 1987, Volume: 9, Issue:5

    Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Drug Administration Schedule; Female; Humans; Imidazol

1987
Miconazole. A monograph.
    American pharmacy, 1987, Volume: NS27, Issue:10

    Topics: Dermatomycoses; Female; Humans; Miconazole; Nonprescription Drugs; Pregnancy; United States

1987
Treatment of vaginal candidiasis in pregnant women.
    Clinical therapeutics, 1986, Volume: 8, Issue:5

    Topics: Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Female; Humans; Imidazoles; Micon

1986
[Congenital cutaneous candidiasis. 2 case reports].
    Pediatrie, 1986, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Candidiasis, Cutaneous; Candidiasis, Vulvovaginal; Female; Humans; Infant, Newbor

1986
Imidazole antimycotics: inhibitors of steroid aromatase.
    Biochemical pharmacology, 1985, Apr-01, Volume: 34, Issue:7

    Topics: Antifungal Agents; Aromatase Inhibitors; Cholesterol; Cytochrome P-450 Enzyme System; Female; Humans

1985