miconazole has been researched along with Otitis Externa in 16 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Otitis Externa: Inflammation of the OUTER EAR including the external EAR CANAL, cartilages of the auricle (EAR CARTILAGE), and the TYMPANIC MEMBRANE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A topical preparation containing miconazole, polymyxin and prednisolone was shown to be more effective in the treatment of otitis externa in 167 dogs than 2 other ear preparations containing antibiotics, an antimycotic and a corticosteroid." | 9.07 | A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs. ( Hughes, KL; Studdert, VP, 1991) |
| " Eighty-five patients with otitis externa were treated with one of two preparations between August 1980 and April 1982 -- 54 were treated with a cream containing miconazole nitrate and hydrocortisone (Daktacort; Janssen) and 31 with a preparation containing neomycin (Kenacomb; Squibb); Sixty eight per cent of the patients were cured within 1 week with both preparations." | 9.05 | Treatment of otitis externa with miconazole nitrate. A comparative study involving 85 cases. ( Bak, JP; Wagenfeld, DJ, 1983) |
| "Hypochlorous acid is a suitable cleaning solution for canine OE." | 5.91 | Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa. ( Baumann, KN; Boehm, T; Dörfelt, S; Kasper, B; Mueller, RS; Udraite-Vovk, L, 2023) |
| "Miconazole was bactericidal against all Staphylococcus strains." | 5.39 | The joint in vitro action of polymyxin B and miconazole against pathogens associated with canine otitis externa from three European countries. ( Cieslicki, M; Meyer, M; Pietschmann, S; Voget, M, 2013) |
| "A topical preparation containing miconazole, polymyxin and prednisolone was shown to be more effective in the treatment of otitis externa in 167 dogs than 2 other ear preparations containing antibiotics, an antimycotic and a corticosteroid." | 5.07 | A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs. ( Hughes, KL; Studdert, VP, 1991) |
| " Eighty-five patients with otitis externa were treated with one of two preparations between August 1980 and April 1982 -- 54 were treated with a cream containing miconazole nitrate and hydrocortisone (Daktacort; Janssen) and 31 with a preparation containing neomycin (Kenacomb; Squibb); Sixty eight per cent of the patients were cured within 1 week with both preparations." | 5.05 | Treatment of otitis externa with miconazole nitrate. A comparative study involving 85 cases. ( Bak, JP; Wagenfeld, DJ, 1983) |
| "Antimicrobial therapy using a combination of polymyxin B and miconazole is effective against the main bacterial pathogens associated with otitis externa in dogs, and a synergistic effect of both drugs has been shown previously." | 3.81 | Is transmission electron microscopy (TEM) a promising approach for qualitative and quantitative investigations of polymyxin B and miconazole interactions with cellular and subcellular structures of Staphylococcus pseudintermedius, Escherichia coli, Pseudo ( Cieslicki, M; Hauck, R; Lieber-Tenorio, E; Lorenz, D; Meyer, M; Voget, M, 2015) |
| "Twenty dogs with otitis externa in both ears and numerous Malassezia species yeasts on cytological examination were treated in one ear with a combination product containing clotrimazole, marbofloxacin and dexamethasone, and in the other ear with a topical antifungal containing miconazole." | 3.73 | Comparison of an antifungal agent with a mixture of antifungal, antibiotic and corticosteroid agents for the treatment of Malassezia species otitis in dogs. ( Bensignor, E; Grandemange, E, 2006) |
| "Hypochlorous acid is a suitable cleaning solution for canine OE." | 1.91 | Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa. ( Baumann, KN; Boehm, T; Dörfelt, S; Kasper, B; Mueller, RS; Udraite-Vovk, L, 2023) |
| "Miconazole was bactericidal against all Staphylococcus strains." | 1.39 | The joint in vitro action of polymyxin B and miconazole against pathogens associated with canine otitis externa from three European countries. ( Cieslicki, M; Meyer, M; Pietschmann, S; Voget, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 6 (37.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Mueller, RS | 2 |
| Baumann, KN | 2 |
| Boehm, T | 2 |
| Dörfelt, S | 2 |
| Kasper, B | 2 |
| Udraite-Vovk, L | 2 |
| Pietschmann, S | 1 |
| Meyer, M | 2 |
| Voget, M | 2 |
| Cieslicki, M | 2 |
| Chiavassa, E | 1 |
| Tizzani, P | 1 |
| Peano, A | 2 |
| Lorenz, D | 1 |
| Lieber-Tenorio, E | 1 |
| Hauck, R | 1 |
| Hensel, P | 1 |
| Austel, M | 1 |
| Wooley, RE | 1 |
| Keys, D | 1 |
| Ritchie, BW | 1 |
| Vennewald, I | 1 |
| Klemm, E | 1 |
| Ghibaudo, G | 1 |
| Bensignor, E | 1 |
| Grandemange, E | 1 |
| Bak, JP | 1 |
| Wagenfeld, DJ | 1 |
| Guedeja-Marron, J | 1 |
| Blanco, JL | 1 |
| Garcia, ME | 1 |
| Gedek, B | 1 |
| Brutzel, K | 1 |
| Gerlach, R | 1 |
| Netzer, F | 1 |
| Rocken, H | 1 |
| Unger, H | 1 |
| Symoens, J | 1 |
| Georgiev, VS | 1 |
| Bell, A | 1 |
| Studdert, VP | 1 |
| Hughes, KL | 1 |
| Doñamayor Hernández, C | 1 |
| Uchida, Y | 1 |
| Nakade, T | 1 |
| Kitazawa, K | 1 |
2 reviews available for miconazole and Otitis Externa
| Article | Year |
|---|---|
Otomycosis: Diagnosis and treatment.
Topics: Administration, Topical; Amphotericin B; Anti-Infective Agents; Antifungal Agents; Clotrimazole; Dru | 2010 |
Treatment and developmental therapeutics in aspergillosis. 2. Azoles and other antifungal drugs.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Azoles; Clotrim | 1992 |
4 trials available for miconazole and Otitis Externa
| Article | Year |
|---|---|
In vitro and in vivo evaluation of a potentiated miconazole aural solution in chronic Malassezia otitis externa in dogs.
Topics: Administration, Topical; Animals; Chelating Agents; Dermatomycoses; Dogs; Double-Blind Method; Malas | 2009 |
Treatment of otitis externa with miconazole nitrate. A comparative study involving 85 cases.
Topics: Clinical Trials as Topic; Humans; Imidazoles; Miconazole; Neomycin; Otitis Externa | 1983 |
A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs.
Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Hypersensitivity; Miconazole; Otitis Externa; | 1991 |
A clinical trial of a topical preparation of miconazole, polymyxin and prednisolone in the treatment of otitis externa in dogs.
Topics: Administration, Topical; Animals; Betamethasone; Disulfiram; Dog Diseases; Dogs; Drug Combinations; | 1991 |
10 other studies available for miconazole and Otitis Externa
| Article | Year |
|---|---|
Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa.
Topics: Animals; Dog Diseases; Dogs; Ear Canal; Hypochlorous Acid; Miconazole; Otitis Externa; Polymyxin B | 2023 |
Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa.
Topics: Animals; Dog Diseases; Dogs; Ear Canal; Hypochlorous Acid; Miconazole; Otitis Externa; Polymyxin B | 2023 |
Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa.
Topics: Animals; Dog Diseases; Dogs; Ear Canal; Hypochlorous Acid; Miconazole; Otitis Externa; Polymyxin B | 2023 |
Evaluation of hypochlorous acid as an ear flush in dogs with chronic otitis externa.
Topics: Animals; Dog Diseases; Dogs; Ear Canal; Hypochlorous Acid; Miconazole; Otitis Externa; Polymyxin B | 2023 |
The joint in vitro action of polymyxin B and miconazole against pathogens associated with canine otitis externa from three European countries.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Dog Diseases; Dogs; Drug Synergism; Europe; Micon | 2013 |
In vitro antifungal susceptibility of Malassezia pachydermatis strains isolated from dogs with chronic and acute otitis externa.
Topics: Animals; Antifungal Agents; Chronic Disease; Clotrimazole; Dog Diseases; Dogs; Drug Resistance, Fung | 2014 |
Is transmission electron microscopy (TEM) a promising approach for qualitative and quantitative investigations of polymyxin B and miconazole interactions with cellular and subcellular structures of Staphylococcus pseudintermedius, Escherichia coli, Pseudo
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Dog Diseases; Dogs; Drug Synergism; Escherichia c | 2015 |
Chronic monolateral otomycosis in a dog caused by Aspergillus ochraceus.
Topics: Administration, Topical; Animals; Antifungal Agents; Aspergillosis; Aspergillus ochraceus; Chronic D | 2010 |
Comparison of an antifungal agent with a mixture of antifungal, antibiotic and corticosteroid agents for the treatment of Malassezia species otitis in dogs.
Topics: Administration, Topical; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Antifungal Agents; | 2006 |
Antimicrobial sensitivity in microorganisms isolated from canine otitis externa.
Topics: Amphotericin B; Animals; Antifungal Agents; Dog Diseases; Dogs; Econazole; Miconazole; Microbial Sen | 1997 |
The role of Pityrosporum pachydermatis in otitis externa of dogs: evaluation of a treatment with miconazole.
Topics: Animals; Candida albicans; Dog Diseases; Dogs; Ear, External; Imidazoles; Malassezia; Miconazole; My | 1979 |
[Ear infections by Aspergillus].
Topics: Adolescent; Adult; Aged; Aspergillosis; Aspergillus flavus; Aspergillus fumigatus; Aspergillus niger | 1990 |
In vitro activity of five antifungal agents against Malassezia pachydermatis.
Topics: Animals; Antifungal Agents; Clotrimazole; Dog Diseases; Dogs; Humans; Ketoconazole; Malassezia; Mico | 1990 |