miconazole has been researched along with Neutropenia in 12 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A combined therapy using miconazole (MCZ) and G-CSF was evaluated in clinical patients who developed deep-seated mycoses and fever of unknown etiology following chemotherapy for malignant gyneco-obstetrical tumors." | 9.07 | [Clinical evaluation of combined use of miconazole and G-CSF on deep-seated mycoses in patients with gynecological cancers]. ( Banzai, M; Chimura, T; Hirayama, T; Numazaki, M; Oda, T; Saito, N, 1994) |
| "Patients treated with cytotoxic therapy expected to produce neutropenia lasting two or more weeks were randomly assigned in a double-blind study to receive intravenous miconazole or placebo concomitant with empiric antibiotics to test whether miconazole can prevent fungal sepsis." | 9.06 | Prevention of fungal sepsis in patients with prolonged neutropenia: a randomized, double-blind, placebo-controlled trial of intravenous miconazole. ( Braine, HG; Merz, WG; Saral, R; Vaughan, WP; Wingard, JR, 1987) |
| "A combined therapy using miconazole (MCZ) and G-CSF was evaluated in clinical patients who developed deep-seated mycoses and fever of unknown etiology following chemotherapy for malignant gyneco-obstetrical tumors." | 5.07 | [Clinical evaluation of combined use of miconazole and G-CSF on deep-seated mycoses in patients with gynecological cancers]. ( Banzai, M; Chimura, T; Hirayama, T; Numazaki, M; Oda, T; Saito, N, 1994) |
| "Patients treated with cytotoxic therapy expected to produce neutropenia lasting two or more weeks were randomly assigned in a double-blind study to receive intravenous miconazole or placebo concomitant with empiric antibiotics to test whether miconazole can prevent fungal sepsis." | 5.06 | Prevention of fungal sepsis in patients with prolonged neutropenia: a randomized, double-blind, placebo-controlled trial of intravenous miconazole. ( Braine, HG; Merz, WG; Saral, R; Vaughan, WP; Wingard, JR, 1987) |
| "Ketoconazole or miconazole was randomly administered to 42 and 46 neutropenic patients respectively." | 2.65 | Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. ( Cruciani, M; Klastersky, J; Meunier-Carpentier, F, 1983) |
| "Patients with cancer complicated by neutropenia." | 2.40 | Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia. ( Gøtzsche, PC; Johansen, HK, 1997) |
| "Invasive fungal infections are becoming increasingly frequent among immunocompromised patients and especially among cancer patients." | 1.27 | Treatment of mycoses in cancer patients. ( Meunier-Carpentier, F, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 7 (58.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maksymiuk, AW | 1 |
| Thongprasert, S | 1 |
| Hopfer, R | 1 |
| Luna, M | 1 |
| Fainstein, V | 1 |
| Bodey, GP | 1 |
| Meunier-Carpentier, F | 2 |
| Cruciani, M | 1 |
| Klastersky, J | 1 |
| Chimura, T | 1 |
| Hirayama, T | 1 |
| Banzai, M | 1 |
| Oda, T | 1 |
| Saito, N | 1 |
| Numazaki, M | 1 |
| Egger, T | 1 |
| Gratwohl, A | 1 |
| Tichelli, A | 1 |
| Uhr, M | 1 |
| Stebler Gysi, C | 1 |
| Passweg, J | 1 |
| Pless, M | 1 |
| Wernli, M | 1 |
| Buser, U | 1 |
| Wuhrmann, J | 1 |
| Chubachi, A | 2 |
| Miura, I | 2 |
| Ohshima, A | 2 |
| Nishinari, T | 1 |
| Nimura, T | 2 |
| Niitsu, H | 2 |
| Miura, AB | 2 |
| Gøtzsche, PC | 1 |
| Johansen, HK | 1 |
| Myoken, Y | 2 |
| Sugata, T | 1 |
| Kyo, T | 1 |
| Fujihara, M | 1 |
| Mikami, Y | 1 |
| Wiley, JM | 1 |
| Smith, N | 1 |
| Leventhal, BG | 1 |
| Graham, ML | 1 |
| Strauss, LC | 1 |
| Hurwitz, CA | 1 |
| Modlin, J | 1 |
| Mellits, D | 1 |
| Baumgardner, R | 1 |
| Corden, BJ | 1 |
| Wingard, JR | 1 |
| Vaughan, WP | 1 |
| Braine, HG | 1 |
| Merz, WG | 1 |
| Saral, R | 1 |
| Hatfield, SM | 1 |
| Crane, LR | 1 |
| Duman, K | 1 |
| Karanes, C | 1 |
| Kiel, RJ | 1 |
1 review available for miconazole and Neutropenia
| Article | Year |
|---|---|
Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Myco | 1997 |
4 trials available for miconazole and Neutropenia
| Article | Year |
|---|---|
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients.
Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Keto | 1983 |
[Clinical evaluation of combined use of miconazole and G-CSF on deep-seated mycoses in patients with gynecological cancers].
Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Female; Genital Neoplasms, Female; Gr | 1994 |
Comparison of fluconazole with oral polyenes in the prevention of fungal infections in neutropenic patients. A prospective, randomized, single-center study.
Topics: Adolescent; Adult; Aged; Female; Fluconazole; Humans; Immunocompromised Host; Male; Miconazole; Midd | 1995 |
Prevention of fungal sepsis in patients with prolonged neutropenia: a randomized, double-blind, placebo-controlled trial of intravenous miconazole.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Amphotericin B; Bacterial Infections; Bone Marrow Transpla | 1987 |
7 other studies available for miconazole and Neutropenia
| Article | Year |
|---|---|
Systemic candidiasis in cancer patients.
Topics: Acute Disease; Amphotericin B; Bacterial Infections; Bacteriological Techniques; Candida; Candidiasi | 1984 |
Treatment of mycoses in cancer patients.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis; Candidiasis, Oral; Drug Therapy, Comb | 1983 |
Risk factors for hepatosplenic abscesses in patients with acute leukemia receiving empiric azole treatment.
Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Candidiasis; Female; Fever; Fluconazole; Humans; Le | 1994 |
Notable clinical changes of hepatosplenic abscesses in febrile neutropenic patients receiving empiric antifungal treatment with azoles.
Topics: Abscess; Antifungal Agents; Candidiasis; Fever; Fluconazole; Humans; Leukemia; Liver Abscess; Lympho | 1994 |
Antifungal susceptibility of Aspergillus species isolated from invasive oral infection in neutropenic patients with hematologic malignancies.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Aspergillosis; Aspergillus; D | 1999 |
Invasive fungal disease in pediatric acute leukemia patients with fever and neutropenia during induction chemotherapy: a multivariate analysis of risk factors.
Topics: Adolescent; Adult; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pr | 1990 |
Miconazole-induced alteration in tobramycin pharmacokinetics.
Topics: Adult; Body Weight; Bone Marrow Transplantation; Cholesterol; Drug Interactions; Female; Humans; Kin | 1986 |