Page last updated: 2024-10-31

miconazole and Neoplasms

miconazole has been researched along with Neoplasms in 14 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Ketoconazole or miconazole was randomly administered to 42 and 46 neutropenic patients respectively."2.65Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. ( Cruciani, M; Klastersky, J; Meunier-Carpentier, F, 1983)
"Patients with cancer complicated by neutropenia."2.40Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia. ( Gøtzsche, PC; Johansen, HK, 1997)
"Disseminated candidiasis is likely to become an increasing problem in cancer patients."1.27Candidiasis in cancer patients. ( Bodey, GP, 1984)
"Invasive fungal infections are becoming increasingly frequent among immunocompromised patients and especially among cancer patients."1.27Treatment of mycoses in cancer patients. ( Meunier-Carpentier, F, 1983)
"Miconazole was most effective against the Candida spp."1.26In vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against Candida spp. and Torulopsis glabrata recovered from cancer patients. ( Moody, MR; Morris, MJ; Schimpff, SC; Young, VM, 1980)
"The different forms of hospital infections have been reviewed and classified as 1."1.26[Infections in children with malignant disease (author's transl)]. ( Krepler, P, 1979)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Venepally, V1
Prasad, RBN1
Poornachandra, Y1
Kumar, CG1
Jala, RCR1
Schierholz, JM1
Nagelschmidt, K1
Nagelschmidt, M1
Lefering, R1
Yücel, N1
Beuth, J1
Sheklakov, ND1
Rukavishnikova, VM1
Bodey, GP3
Maksymiuk, AW1
Thongprasert, S1
Hopfer, R1
Luna, M1
Fainstein, V1
Moody, MR1
Young, VM1
Morris, MJ1
Schimpff, SC1
Chretien, JH1
Garagusi, VF1
Young, LS1
Meunier-Carpentier, F3
Cruciani, M1
Klastersky, J1
Gøtzsche, PC1
Johansen, HK1
Krepler, P1
Jordan, WM1
Rodriguez, V1
Ketchel, SJ1
Henney, J1

Reviews

4 reviews available for miconazole and Neoplasms

ArticleYear
[Imidazole preparations in mycology].
    Vestnik dermatologii i venerologii, 1984, Issue:6

    Topics: Animals; Antifungal Agents; Candidiasis; Clotrimazole; Coccidioidomycosis; Cryptococcosis; Dermatomy

1984
Current management of fungal enteritis.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Amphotericin B; Antifungal Agents; Candidiasis; Diarrhea; Enteritis; Histoplasmosis; Humans; Imidazo

1982
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of fungal infections.
    The American journal of medicine, 1984, Volume: 76, Issue:4

    Topics: Administration, Oral; Administration, Topical; Amphotericin B; Antifungal Agents; Candidiasis; Clini

1984
Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia.
    BMJ (Clinical research ed.), 1997, Apr-26, Volume: 314, Issue:7089

    Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Myco

1997

Trials

3 trials available for miconazole and Neoplasms

ArticleYear
Antimicrobial central venous catheters in oncology: efficacy of a rifampicin-miconazole-releasing catheter.
    Anticancer research, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antifungal Agents; Bacteria

2010
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1

    Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Keto

1983
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of fungal infections.
    The American journal of medicine, 1984, Volume: 76, Issue:4

    Topics: Administration, Oral; Administration, Topical; Amphotericin B; Antifungal Agents; Candidiasis; Clini

1984

Other Studies

8 other studies available for miconazole and Neoplasms

ArticleYear
Synthesis of novel ethyl 1-ethyl-6-fluoro-7-(fatty amido)-1,4-dihydro-4-oxoquinoline-3-carboxylate derivatives and their biological evaluation.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Bac

2016
Candidiasis in cancer patients.
    The American journal of medicine, 1984, Oct-30, Volume: 77, Issue:4D

    Topics: Amphotericin B; Antibodies, Fungal; Candidiasis; Cephalosporins; Humans; Ketoconazole; Leukemia; Mic

1984
Systemic candidiasis in cancer patients.
    The American journal of medicine, 1984, Oct-30, Volume: 77, Issue:4D

    Topics: Acute Disease; Amphotericin B; Bacterial Infections; Bacteriological Techniques; Candida; Candidiasi

1984
In vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against Candida spp. and Torulopsis glabrata recovered from cancer patients.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:5

    Topics: Antifungal Agents; Candida; Drug Synergism; Humans; Imidazoles; Ketoconazole; Miconazole; Microbial

1980
The outlook for antifungal prophylaxis in the compromised host.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 9, Issue:5

    Topics: Candidiasis; Humans; Imidazoles; Immunity; Ketoconazole; Miconazole; Mycoses; Neoplasms; Nystatin; P

1982
Treatment of mycoses in cancer patients.
    The American journal of medicine, 1983, Jan-24, Volume: 74, Issue:1B

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis; Candidiasis, Oral; Drug Therapy, Comb

1983
[Infections in children with malignant disease (author's transl)].
    Wiener klinische Wochenschrift, 1979, Nov-09, Volume: 91, Issue:21

    Topics: Amphotericin B; Antineoplastic Agents; Bacterial Infections; Blood Transfusion; Child; Communicable

1979
Miconazole therapy for treatment of fungal infections in cancer patients.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Candida; Candidiasis; Female; Humans; Imidazoles; Male; Miconazole; Middle

1979