Page last updated: 2024-10-31

miconazole and Nail Fungus

miconazole has been researched along with Nail Fungus in 14 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Research Excerpts

ExcerptRelevanceReference
"The objective of this 2-year, double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence."9.11Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%. ( St Clair, KR; Warshaw, EM, 2005)
"To compare the safety of itraconazole 200 mg once daily for 3 months, with or without itraconazole 200 mg once weekly for a further 3 months, with that of miconazole cream twice daily for 6 months, in the treatment of onychomycosis."9.08Itraconazole in the treatment of onychomycosis: a double-blind comparison with miconazole. ( De Doncker, P; Haneke, E; Heremans, A; Tajerbashi, M, 1998)
"13 patients with distal subungual onychomycosis in a total of 48 dermatophyte-infected nails were treated with chemomechanical, partial nail avulsion followed by topical miconazole for 8 weeks."7.66Treatment of onychomycosis by partial nail avulsion and topical miconazole. ( Rollman, O, 1982)
"Treatment of onychomycosis is usually unsatisfactory."6.65The treatment of onychomycosis with miconazole tincture. ( Bentley-Phillips, B, 1982)
"The difficulties encountered in the treatment of onychomycosis are primarily related to the necessity of prolonged systemic therapy."5.27The treatment of onychomycosis with a new form of tioconazole. ( De Simone, C; Ruffilli, MP; Tulli, A, 1988)
"The objective of this 2-year, double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence."5.11Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%. ( St Clair, KR; Warshaw, EM, 2005)
"To compare the safety of itraconazole 200 mg once daily for 3 months, with or without itraconazole 200 mg once weekly for a further 3 months, with that of miconazole cream twice daily for 6 months, in the treatment of onychomycosis."5.08Itraconazole in the treatment of onychomycosis: a double-blind comparison with miconazole. ( De Doncker, P; Haneke, E; Heremans, A; Tajerbashi, M, 1998)
"13 patients with distal subungual onychomycosis in a total of 48 dermatophyte-infected nails were treated with chemomechanical, partial nail avulsion followed by topical miconazole for 8 weeks."3.66Treatment of onychomycosis by partial nail avulsion and topical miconazole. ( Rollman, O, 1982)
"Treatment of onychomycosis is usually unsatisfactory."2.65The treatment of onychomycosis with miconazole tincture. ( Bentley-Phillips, B, 1982)
"Onychomycosis is an infection of the nail unit by a fungus."1.43Onychomycosis in diabetic patients in Fako Division of Cameroon: prevalence, causative agents, associated factors and antifungal sensitivity patterns. ( Atashili, J; Eba, M; Fuh, AN; Kwenti, ET; Mouliom, RN; Nchanji, GT; Njunda, AL, 2016)
"Onychomycosis is one of the most common infections of the nail."1.35Onychomycosis by Chaetomium spp. ( Ceballos, JD; Erchiga, VC; Falcón, CS; Falcón, Mdel M; Florencio, VD; xOrtega, SC, 2009)
"The difficulties encountered in the treatment of onychomycosis are primarily related to the necessity of prolonged systemic therapy."1.27The treatment of onychomycosis with a new form of tioconazole. ( De Simone, C; Ruffilli, MP; Tulli, A, 1988)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's2 (14.29)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christensen, L1
Turner, R1
Weaver, S1
Caserta, F1
Long, L1
Ghannoum, M1
Brown, M1
Eba, M1
Njunda, AL1
Mouliom, RN1
Kwenti, ET1
Fuh, AN1
Nchanji, GT1
Atashili, J1
Ghislanzoni, M1
Warshaw, EM1
St Clair, KR1
Figueiredo, VT1
de Assis Santos, D1
Resende, MA1
Hamdan, JS1
Falcón, CS1
Falcón, Mdel M1
Ceballos, JD1
Florencio, VD1
Erchiga, VC1
xOrtega, SC1
Bentley-Phillips, B1
Rollman, O1
Marcano, C1
Borelli, D1
Crozier, WJ1
Wise, KA1
Haneke, E1
Tajerbashi, M1
De Doncker, P1
Heremans, A1
Vanderdonckt, J1
Lauwers, W1
Bockaert, J1
Achten, G1
Degreef, H1
Dockx, P1
Tulli, A1
Ruffilli, MP1
De Simone, C1

Trials

3 trials available for miconazole and Nail Fungus

ArticleYear
Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:4

    Topics: Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses; Humans; Male; Miconazole; Mid

2005
The treatment of onychomycosis with miconazole tincture.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Jul-10, Volume: 62, Issue:2

    Topics: Administration, Topical; Adult; Aged; Candidiasis; Child, Preschool; Clinical Trials as Topic; Femal

1982
Itraconazole in the treatment of onychomycosis: a double-blind comparison with miconazole.
    Dermatology (Basel, Switzerland), 1998, Volume: 196, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antifungal Agents; Double-Blind Method; Female; Foot Dermatoses;

1998

Other Studies

11 other studies available for miconazole and Nail Fungus

ArticleYear
Evaluation of the Ability of a Novel Miconazole Formulation To Penetrate Nail by Using Three
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:7

    Topics: Administration, Topical; Animals; Antifungal Agents; Cattle; Hoof and Claw; Humans; Miconazole; Nail

2017
Onychomycosis in diabetic patients in Fako Division of Cameroon: prevalence, causative agents, associated factors and antifungal sensitivity patterns.
    BMC research notes, 2016, Nov-22, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Cameroon; Cross-Sectional Studies

2016
Tinea incognito due to Trichophyton rubrum responsive to topical therapy with isoconazole plus corticosteroid cream.
    Mycoses, 2008, Volume: 51 Suppl 4

    Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents; Antifungal Agents; Diflucortolone; Drug

2008
Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections.
    Mycopathologia, 2007, Volume: 164, Issue:1

    Topics: Antifungal Agents; Brazil; Candida; Candidiasis; Ciclopirox; Fluconazole; Hand Dermatoses; Humans; I

2007
Onychomycosis by Chaetomium spp.
    Mycoses, 2009, Volume: 52, Issue:1

    Topics: Animals; Antifungal Agents; Chaetomium; Child; Female; Humans; Itraconazole; Miconazole; Onychomycos

2009
Treatment of onychomycosis by partial nail avulsion and topical miconazole.
    Dermatologica, 1982, Volume: 165, Issue:1

    Topics: Administration, Topical; Adult; Aged; Drug Therapy, Combination; Foot Dermatoses; Hand Dermatoses; H

1982
[Tinea unguis caused by Nannizzia gypsea (+)].
    Mycopathologia, 1983, Feb-17, Volume: 81, Issue:2

    Topics: Adult; Female; Griseofulvin; Hand Dermatoses; Humans; Miconazole; Microsporum; Onychomycosis

1983
Onychomycosis due to Pityrosporum.
    The Australasian journal of dermatology, 1993, Volume: 34, Issue:3

    Topics: Adult; Aged; Chloroform; Female; Hand Dermatoses; Humans; Ketoconazole; Malassezia; Male; Miconazole

1993
Miconazole alcoholic solution in the treatment of mycotic nail infections.
    Mykosen, 1976, Volume: 19, Issue:7

    Topics: Adult; Aged; Candida; Drug Evaluation; Humans; Imidazoles; Male; Miconazole; Middle Aged; Mitosporic

1976
Treatment of onychomycosis with a solution of miconazole 2% in alcohol.
    Mykosen, 1977, Volume: 20, Issue:7

    Topics: Administration, Topical; Adult; Alcohols; Drug Evaluation; Female; Humans; Imidazoles; Male; Miconaz

1977
The treatment of onychomycosis with a new form of tioconazole.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:3

    Topics: Adult; Antifungal Agents; Female; Humans; Imidazoles; Male; Miconazole; Middle Aged; Onychomycosis

1988