miconazole has been researched along with Leucocythaemia in 15 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of miconazole was evaluated in 9 documented fungal infections, 4 of which were candidal sepsis." | 3.67 | [Therapeutic effect of miconazole on fungal infection in patients with hematological malignancies]. ( Nagai, K; Nakayama, S; Yabe, H; Yoshida, T, 1984) |
| "Seven patients with hematologic malignancies who were treated with miconazole for either suspected or proven fungal infections developed eight episodes of major adverse cardiorespiratory and anaphylactic reactions." | 3.66 | Cardiorespiratory toxicity due to miconazole. ( Bodey, GP; Fainstein, V, 1980) |
| "In 24 patients with advanced malignant diseases, mainly leukaemias and lymphomas, 35 episodes of oral candidiasis were treated with topical application of miconazole." | 3.65 | Treatment of oral candidiasis in debilitated patients with miconazole--a new potent antifungal drug. ( Brincker, H, 1976) |
| "The miconazole-treated patients remained clinically free of mycosis for 252 out of 264 treatment days, while the placebo-treated patients remained free of mycosis for only 263 out or 338 treatment days (p = 0." | 2.64 | Prophylactic treatment with miconazole in patients highly predisposed to fungal infection. A placebo-controlled double-blind study. ( Brincker, H, 1978) |
| "Disseminated candidiasis is likely to become an increasing problem in cancer patients." | 1.27 | Candidiasis in cancer patients. ( Bodey, GP, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bodey, GP | 3 |
| Maksymiuk, AW | 1 |
| Thongprasert, S | 1 |
| Hopfer, R | 1 |
| Luna, M | 1 |
| Fainstein, V | 2 |
| Nagai, K | 1 |
| Yabe, H | 1 |
| Yoshida, T | 1 |
| Nakayama, S | 1 |
| Chubachi, A | 2 |
| Miura, I | 2 |
| Ohshima, A | 2 |
| Nishinari, T | 1 |
| Nimura, T | 2 |
| Niitsu, H | 2 |
| Miura, AB | 2 |
| Myoken, Y | 2 |
| Sugata, T | 1 |
| Kyo, T | 1 |
| Fujihara, M | 1 |
| Mikami, Y | 1 |
| Brincker, H | 3 |
| Michaux, JL | 1 |
| Jacquemin, P | 1 |
| Cornu, G | 1 |
| Wauters, G | 1 |
| Gigi, J | 1 |
| Noel, H | 1 |
| Turine, JB | 1 |
| Ferrant, A | 2 |
| Grulich, M | 1 |
| Dörffel, W | 1 |
| Reuter, G | 1 |
| Gemeinhardt, H | 1 |
| Stuchlik, S | 1 |
| De Beule, F | 1 |
| Bercy, P | 1 |
| Verhagen, C | 1 |
| Stalpers, LJ | 1 |
| de Pauw, BE | 1 |
| Haanen, C | 1 |
1 trial available for miconazole and Leucocythaemia
| Article | Year |
|---|---|
Prophylactic treatment with miconazole in patients highly predisposed to fungal infection. A placebo-controlled double-blind study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Candida; Clinical Trials as Topic; Double- | 1978 |
14 other studies available for miconazole and Leucocythaemia
| Article | Year |
|---|---|
Candidiasis in cancer patients.
Topics: Amphotericin B; Antibodies, Fungal; Candidiasis; Cephalosporins; Humans; Ketoconazole; Leukemia; Mic | 1984 |
Systemic candidiasis in cancer patients.
Topics: Acute Disease; Amphotericin B; Bacterial Infections; Bacteriological Techniques; Candida; Candidiasi | 1984 |
[Therapeutic effect of miconazole on fungal infection in patients with hematological malignancies].
Topics: Adolescent; Adult; Aged; Candidiasis; Drug Evaluation; Esophagitis; Female; Hodgkin Disease; Humans; | 1984 |
Cardiorespiratory toxicity due to miconazole.
Topics: Adult; Anaphylaxis; Female; Heart Arrest; Humans; Imidazoles; Leukemia; Male; Miconazole; Middle Age | 1980 |
Risk factors for hepatosplenic abscesses in patients with acute leukemia receiving empiric azole treatment.
Topics: Abscess; Acute Disease; Adolescent; Adult; Aged; Candidiasis; Female; Fever; Fluconazole; Humans; Le | 1994 |
Notable clinical changes of hepatosplenic abscesses in febrile neutropenic patients receiving empiric antifungal treatment with azoles.
Topics: Abscess; Antifungal Agents; Candidiasis; Fever; Fluconazole; Humans; Leukemia; Liver Abscess; Lympho | 1994 |
Antifungal susceptibility of Aspergillus species isolated from invasive oral infection in neutropenic patients with hematologic malignancies.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Aspergillosis; Aspergillus; D | 1999 |
Miconazole in oral candidiasis.
Topics: Administration, Oral; Candidiasis, Oral; Humans; Leukemia; Miconazole; Middle Aged; Tablets | 1977 |
Use of miconazole for prevention of opportunistic fungal infection during treatment of haematological malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Leukemia; Male; Miconazole; Middl | 1977 |
[Experiences with miconazole in the prevention and therapy of candidiasis].
Topics: Candidiasis; Child; Drug Evaluation; Humans; Imidazoles; Leukemia; Miconazole | 1979 |
[Treatment of mouth candidiasis in leukemia patients with parenterally administered miconazole].
Topics: Adult; Bronchial Diseases; Candidiasis, Oral; Chemical Phenomena; Chemistry; Female; Humans; Imidazo | 1975 |
Treatment of oral candidiasis in debilitated patients with miconazole--a new potent antifungal drug.
Topics: Administration, Topical; Adolescent; Adult; Aged; Candidiasis, Oral; Drug Evaluation; Female; Humans | 1976 |
The effectiveness of a preventive regimen on the periodontal health of patients undergoing chemotherapy for leukemia and lymphoma.
Topics: Acyclovir; Amphotericin B; Ceftazidime; Chlorhexidine; Dental Plaque Index; Fluconazole; Humans; Imm | 1991 |
Drug-induced skin reactions in patients with acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Allopurinol; Cephalosporins; Drug Combinations; Drug Eruptions; Female; Humans | 1987 |