miconazole has been researched along with Keratitis in 35 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Keratitis: Inflammation of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on a case of keratitis with hypopion by Fusarium monilinforme, in a patient with palpebral retraction and light exophthalmos caused by hyperthyroidism." | 7.69 | Mycotic keratitis by Fusarium moniliforme. ( Amalfitano, G; Bonomi, L; Pagliarusco, A; Polonelli, L; Tomazzoli, L, 1995) |
| "Two patients, a 44-year-old man and a 53-year-old man, with fungal keratitis were successfully treated with intravenously infused miconazole, a synthetic imidazole derivative." | 7.67 | The effects of intravenous miconazole on fungal keratitis. ( Ishibashi, Y; Matsumoto, Y; Takei, K, 1984) |
| "We report on a case of keratitis with hypopion by Fusarium monilinforme, in a patient with palpebral retraction and light exophthalmos caused by hyperthyroidism." | 3.69 | Mycotic keratitis by Fusarium moniliforme. ( Amalfitano, G; Bonomi, L; Pagliarusco, A; Polonelli, L; Tomazzoli, L, 1995) |
| "Cysts of 2 isolates of Acanthamoeba from the cornea of 2 patients with confirmed Acanthamoeba keratitis were tested in vitro for sensitivity to antimycotic agents such as fluconazole, miconazole, amphotericin-B, pimaricin, antiprotozoal agents such as pentamidine isetionate and antiseptics which could be use in the ophthamological region." | 3.69 | [Evaluation of effective treatment drugs against Acanthamoeba cyst]. ( Asari, S; Endo, T; Shimomura, Y; Tahara, K; Yanagihara, T, 1997) |
| "Two patients, a 44-year-old man and a 53-year-old man, with fungal keratitis were successfully treated with intravenously infused miconazole, a synthetic imidazole derivative." | 3.67 | The effects of intravenous miconazole on fungal keratitis. ( Ishibashi, Y; Matsumoto, Y; Takei, K, 1984) |
| "Intravenous miconazole (90 mg daily for 3 weeks) reduced the intensity of experimental fungal keratitis due to Candida albicans in a group of 10 rabbits." | 3.67 | Intravenous miconazole therapy for experimental keratomycosis in rabbits. ( Ishibashi, Y; Matsumoto, Y, 1985) |
| "I treated seven patients with keratomycosis (four with Candida infections and three with Aspergillus infections) with topical and subconjunctival miconazole." | 3.66 | Miconazole therapy for keratomycosis. ( Foster, CS, 1981) |
| "The extemporaneously prepared miconazole eye drops are effective and safe to use in keratomycosis." | 1.48 | Efficacy and safety of extemporaneously prepared miconazole eye drops in Candida albicans-induced keratomycosis. ( Ababio-Danso, B; Asare, F; Gyanfosu, L; Koffuor, GA; Kyei, S; Nyansah, WB; Peprah-Donkor, K, 2018) |
| "Miconazole was useful at 10 mg/ml concentration by topical drops and subconjunctival injections, but was less useful at 5 mg/ml." | 1.27 | Chemotherapy of Aspergillus fumigatus keratitis: an experimental study. ( Borrás, R; Buesa, FJ; Fons, MA; Garcia de Lomas, J; Nogueira, JM; Rustom, F, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (60.00) | 18.7374 |
| 1990's | 9 (25.71) | 18.2507 |
| 2000's | 2 (5.71) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, S | 1 |
| Sin, WLW | 1 |
| Koh, JJ | 1 |
| Lim, F | 1 |
| Wang, L | 1 |
| Cao, D | 1 |
| Beuerman, RW | 1 |
| Ren, L | 1 |
| Liu, S | 1 |
| Gyanfosu, L | 1 |
| Koffuor, GA | 1 |
| Kyei, S | 1 |
| Ababio-Danso, B | 1 |
| Peprah-Donkor, K | 1 |
| Nyansah, WB | 1 |
| Asare, F | 1 |
| Wada, S | 1 |
| Ode, H | 1 |
| Hobo, S | 1 |
| Niwa, H | 1 |
| Katayama, Y | 1 |
| Takatori, K | 1 |
| Weinstein, WL | 1 |
| Moore, PA | 1 |
| Sanchez, S | 1 |
| Dietrich, UM | 1 |
| Wooley, RE | 1 |
| Ritchie, BW | 1 |
| Hirst, LW | 1 |
| Green, WR | 1 |
| Merz, W | 1 |
| Kaufmann, C | 1 |
| Visvesvara, GS | 1 |
| Jensen, A | 1 |
| Howard, M | 1 |
| Foster, CS | 1 |
| O'Day, DM | 2 |
| Ray, WA | 1 |
| Robinson, R | 1 |
| Head, WS | 2 |
| Minogue, MJ | 1 |
| Francis, IC | 1 |
| Quatermass, P | 1 |
| Kappagoda, MB | 1 |
| Bradbury, R | 1 |
| Walls, RS | 1 |
| Motum, PI | 1 |
| Ishibashi, Y | 9 |
| Matsumoto, Y | 5 |
| Smolin, G | 1 |
| Samy, M | 1 |
| Okumoto, M | 1 |
| Fuerst, D | 1 |
| Takei, K | 1 |
| Kozarsky, AM | 1 |
| Stulting, RD | 1 |
| Waring, GO | 1 |
| Cornell, FM | 1 |
| Wilson, LA | 1 |
| Cavanagh, HD | 1 |
| Pagliarusco, A | 1 |
| Tomazzoli, L | 1 |
| Amalfitano, G | 1 |
| Polonelli, L | 1 |
| Bonomi, L | 1 |
| Tahara, K | 1 |
| Asari, S | 1 |
| Shimomura, Y | 1 |
| Endo, T | 2 |
| Yanagihara, T | 1 |
| Sun, B | 1 |
| He, Y | 1 |
| Wang, Y | 1 |
| Yoo, SH | 1 |
| Dursun, D | 1 |
| Dubovy, S | 1 |
| Miller, D | 1 |
| Alfonso, E | 1 |
| Forster, RK | 1 |
| Behar-Cohen, F | 1 |
| Parel, JM | 1 |
| François, J | 1 |
| Rijsselaere, M | 1 |
| Bloom, PA | 1 |
| Laidlaw, DA | 1 |
| Easty, DL | 1 |
| Warnock, DW | 1 |
| Ruben, S | 1 |
| Robinson, RD | 1 |
| Williams, TE | 1 |
| Gedde, SJ | 1 |
| Driebe, WT | 1 |
| Stern, GA | 1 |
| Zaidman, GW | 1 |
| Perry, HD | 1 |
| Donnenfeld, ED | 1 |
| Watanabe, R | 1 |
| Hommura, S | 1 |
| Yasuraoka, K | 1 |
| Ishii, K | 1 |
| Koyama, T | 1 |
| Yagita, K | 1 |
| Mohan, M | 2 |
| Gupta, SK | 2 |
| Kalra, VK | 2 |
| Vajpayee, RB | 2 |
| Sachdev, MS | 2 |
| Kaufman, HE | 2 |
| Luque, AG | 1 |
| Nanni, R | 1 |
| de Bracalenti, BJ | 1 |
| Fitzsimons, R | 1 |
| Peters, AL | 1 |
| Garcia de Lomas, J | 1 |
| Fons, MA | 1 |
| Nogueira, JM | 1 |
| Rustom, F | 1 |
| Borrás, R | 1 |
| Buesa, FJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-inferiority Trial of Iontophoretic Corneal Collagen Crosslinking (CXL) Compared to Standard Corneal Collagen Crosslinking in Progressive Keratoconus.[NCT01868620] | 28 participants (Actual) | Interventional | 2013-05-31 | Terminated (stopped due to The investigator decided to stop the trial due to a lack of inclusion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for miconazole and Keratitis
| Article | Year |
|---|---|
[Comparison of various types of imidazole derivatives for treatment of filamentous fungal keratitis].
Topics: Adolescent; Adult; Antifungal Agents; Drug Therapy, Combination; Econazole; Eye Infections, Fungal; | 1996 |
Silver sulphadiazine in the treatment of mycotic keratitis.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Keratitis; Miconazole; Mycoses; Random Alloca | 1987 |
33 other studies available for miconazole and Keratitis
| Article | Year |
|---|---|
Semisynthesis and Biological Evaluation of Xanthone Amphiphilics as Selective, Highly Potent Antifungal Agents to Combat Fungal Resistance.
Topics: Animals; Antifungal Agents; Aspergillus; Candida; Cell Line; Drug Evaluation, Preclinical; Drug Resi | 2017 |
Efficacy and safety of extemporaneously prepared miconazole eye drops in Candida albicans-induced keratomycosis.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Cornea; Disease Models, Animal; Eye Infec | 2018 |
Mortierella wolfii keratomycosis in a horse.
Topics: Animals; Antifungal Agents; Female; Horse Diseases; Horses; Keratitis; Miconazole; Mortierella; Muco | 2011 |
In vitro efficacy of a buffered chelating solution as an antimicrobial potentiator for antifungal drugs against fungal pathogens obtained from horses with mycotic keratitis.
Topics: Animals; Antifungal Agents; Chelating Agents; Drug Synergism; Horse Diseases; Horses; Itraconazole; | 2006 |
Management of Acanthamoeba keratitis. A case report and review of the literature.
Topics: Adult; Aged; Amebiasis; Combined Modality Therapy; Cornea; Corneal Transplantation; Female; Humans; | 1984 |
Miconazole therapy for keratomycosis.
Topics: Adult; Aged; Aspergillosis; Candidiasis; Corneal Diseases; Female; Humans; Imidazoles; Keratitis; Ke | 1981 |
Efficacy of antifungal agents in the cornea. II. Influence of corticosteroids.
Topics: Adrenal Cortex Hormones; Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; | 1984 |
Successful treatment of fungal keratitis caused by Paecilomyces lilacinus.
Topics: Aged; Humans; Keratitis; Male; Miconazole; Mitosporic Fungi; Mycoses; Natamycin | 1984 |
[Subconjunctival miconazole for Candida keratitis in rabbits].
Topics: Animals; Candidiasis; Female; Keratitis; Male; Miconazole; Rabbits | 1984 |
Effect of soft contact lenses on experimental Pseudomonas and Candida keratitis.
Topics: Animals; Candidiasis; Contact Lenses, Hydrophilic; Female; Gentamicins; Keratitis; Male; Miconazole; | 1984 |
The effects of intravenous miconazole on fungal keratitis.
Topics: Adult; Cornea; Humans; Infusions, Parenteral; Keratitis; Male; Miconazole; Middle Aged; Mitosporic F | 1984 |
Penetrating keratoplasty for exogenous Paecilomyces keratitis followed by postoperative endophthalmitis.
Topics: Aged; Cornea; Female; Humans; Inflammation; Keratitis; Male; Miconazole; Mitosporic Fungi; Mycoses; | 1984 |
Intravenous miconazole in the treatment of keratomycosis.
Topics: Humans; Injections, Intravenous; Keratitis; Male; Miconazole; Middle Aged; Mycoses | 1984 |
[Intravenous miconazole therapy for Candida albicans keratitis in rabbits].
Topics: Animals; Candidiasis; Female; Imidazoles; Injections, Intravenous; Keratitis; Male; Miconazole; Rabb | 1982 |
Mycotic keratitis by Fusarium moniliforme.
Topics: Aged; Amphotericin B; Antifungal Agents; Cornea; Female; Fusarium; Humans; Keratitis; Miconazole; My | 1995 |
[Evaluation of effective treatment drugs against Acanthamoeba cyst].
Topics: Acanthamoeba; Amphotericin B; Animals; Anti-Infective Agents, Local; Antifungal Agents; Antiprotozoa | 1997 |
Lontophoresis for the treatment of paecilomyces keratitis.
Topics: Antifungal Agents; Eye Infections, Fungal; Humans; Iontophoresis; Keratitis; Male; Miconazole; Middl | 2002 |
[Keratomycoses].
Topics: Corneal Diseases; Econazole; Humans; Keratitis; Miconazole; Mycoses | 1979 |
Treatment failure in a case of fungal keratitis caused by Pseudallescheria boydii.
Topics: Antifungal Agents; Eye Infections, Fungal; Humans; Itraconazole; Keratitis; Keratoplasty, Penetratin | 1992 |
Pseudallescheria Boydii keratitis.
Topics: Administration, Topical; Aged; Cornea; Eye Infections, Fungal; Humans; Keratitis; Male; Miconazole; | 1991 |
Anomalous effect of subconjunctival miconazole on Candida albicans keratitis in rabbits.
Topics: Amphotericin B; Animals; Candida albicans; Candidiasis; Conjunctiva; Dose-Response Relationship, Dru | 1991 |
Successful medical management of Acanthamoeba keratitis.
Topics: Amebiasis; Clotrimazole; Humans; Keratitis; Miconazole | 1991 |
Miconazole corneal toxicity.
Topics: Acanthamoeba Keratitis; Adult; Female; Humans; Keratitis; Keratoplasty, Penetrating; Miconazole; Pos | 1991 |
Cryptococcal keratitis after keratoplasty.
Topics: Aged; Cornea; Corneal Transplantation; Cryptococcosis; Cryptococcus neoformans; Humans; Keratitis; M | 1990 |
[Case of Acanthamoeba keratitis].
Topics: Acanthamoeba; Adult; Amebiasis; Animals; Antifungal Agents; Drug Therapy, Combination; Humans; Itrac | 1988 |
Corneal biopsy in the diagnosis of keratomycosis.
Topics: Animals; Biopsy; Cornea; Corneal Diseases; Humans; Keratitis; Male; Miconazole; Middle Aged; Mycoses | 1986 |
Mycotic keratitis caused by Curvularia lunata var. aeria.
Topics: Aged; Cornea; Eye Injuries; Humans; Keratitis; Male; Miconazole; Mitosporic Fungi; Mycoses; Natamyci | 1986 |
Silver sulphadiazine--a new drug for keratomycosis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Female; Humans; Keratitis; Male; Miconazole; Middl | 1987 |
Miconazole and ketoconazole as a satisfactory first-line treatment for keratomycosis.
Topics: Adolescent; Adult; Aged; Child, Preschool; Female; Humans; Keratitis; Ketoconazole; Male; Miconazole | 1986 |
Miconazole and ketoconazole as a satisfactory first-line treatment for keratomycosis.
Topics: Animals; Humans; Keratitis; Ketoconazole; Miconazole; Mycoses; Rabbits | 1986 |
Chemotherapy of Aspergillus fumigatus keratitis: an experimental study.
Topics: Administration, Topical; Amphotericin B; Animals; Aspergillosis; Aspergillus fumigatus; Conjunctiva; | 1985 |
The effects of subconjunctival miconazole in the treatment of experimental Candida keratitis in rabbits.
Topics: Animals; Candida albicans; Candidiasis; Conjunctiva; Cornea; Drug Evaluation; Injections; Keratitis; | 1985 |
Intravenous miconazole therapy for experimental keratomycosis in rabbits.
Topics: Animals; Candidiasis; Corneal Stroma; Corneal Ulcer; Drug Evaluation, Preclinical; Female; Injection | 1985 |