Page last updated: 2024-10-31

miconazole and Innate Inflammatory Response

miconazole has been researched along with Innate Inflammatory Response in 9 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Research Excerpts

ExcerptRelevanceReference
" Subcutaneous injection of miconazole into the rat paw evoked an acute, circumscribed and long-lasting inflammation."3.69Miconazole as inflammatory agent--I. Cellular and pathophysiological effects. ( Hanada, S; Sertié, JA; Sudo, LS; Waisbich, E, 1994)
"Travocort is a combination of 1% isoconazole nitrate (ISN), a broad-spectrum imidazole with established antimicrobial activity and antimycotic efficacy, and 0."2.44The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses. ( Friedrich, M; Havlickova, B, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Yeo, IJ1
Yun, J1
Son, DJ1
Han, SB1
Hong, JT1
Piergiorgio, M1
Havlickova, B1
Friedrich, M1
Kozarsky, AM1
Stulting, RD1
Waring, GO1
Cornell, FM1
Wilson, LA1
Cavanagh, HD1
Gip, L1
Langen, ML1
Nolting, S1
Rogalla, K1
Hanada, S1
Sertié, JA1
Waisbich, E1
Sudo, LS1
Nada, M1
Hanafi, S1
al-Omari, H1
Mokhtar, M1
el-Shamy, S1
Mühlbacher, J1

Reviews

1 review available for miconazole and Innate Inflammatory Response

ArticleYear
The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses.
    Mycoses, 2008, Volume: 51 Suppl 4

    Topics: Administration, Cutaneous; Anti-Inflammatory Agents; Antifungal Agents; Child; Child, Preschool; Der

2008

Trials

3 trials available for miconazole and Innate Inflammatory Response

ArticleYear
[Results of a contralateral comparative study between Travocort cream and Travogen cream in inflammatory and allergic dermatomycoses (author's transl)].
    Mykosen, 1980, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dermatomycoses; Diflucortolone; Double-Bli

1980
Double-blind comparison of miconazole/corticosteroid combination versus miconazole in inflammatory dermatomycoses.
    International journal of dermatology, 1995, Volume: 34, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Child

1995
Naftifine versus miconazole/hydrocortisone in inflammatory dermatophyte infections.
    International journal of dermatology, 1994, Volume: 33, Issue:8

    Topics: Administration, Topical; Adolescent; Adult; Aged; Allylamine; Anti-Inflammatory Agents, Non-Steroida

1994

Other Studies

5 other studies available for miconazole and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Antifungal drug miconazole ameliorated memory deficits in a mouse model of LPS-induced memory loss through targeting iNOS.
    Cell death & disease, 2020, 08-14, Volume: 11, Issue:8

    Topics: Animals; Antifungal Agents; Astrocytes; Brain; Cell Nucleus; Cells, Cultured; Cytokines; Disease Mod

2020
Effective treatment of erythrasma-associated inflammation and pruritus with isoconazole nitrate and diflucortolone valerate combination therapy.
    Mycoses, 2013, Volume: 56 Suppl 1

    Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Antifungal Agents; Diflucortolone; Dr

2013
Penetrating keratoplasty for exogenous Paecilomyces keratitis followed by postoperative endophthalmitis.
    American journal of ophthalmology, 1984, Volume: 98, Issue:5

    Topics: Aged; Cornea; Female; Humans; Inflammation; Keratitis; Male; Miconazole; Mitosporic Fungi; Mycoses;

1984
Miconazole as inflammatory agent--I. Cellular and pathophysiological effects.
    General pharmacology, 1994, Volume: 25, Issue:4

    Topics: Animals; Edema; Inflammation; Leukocyte Count; Male; Miconazole; Rats; Rats, Wistar

1994