miconazole has been researched along with Extravascular Hemolysis in 5 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our recent study showed that clotrimazole has a relative high affinity for heme, inhibits reduced glutathione-dependent heme catabolism, and enhances heme-induced hemolysis." | 3.71 | Effect of antifungal azoles on the heme detoxification system of malarial parasite. ( Hara, S; Huy, NT; Kamei, K; Kanaori, K; Kondo, Y; Serada, S; Tajima, K; Takano, R, 2002) |
| "The miconazole complex was more toxic to erythrocytes than the physical mixture." | 1.30 | Cyclodextrin inclusion complexes of miconazole and econazole--isolation, toxicity on human cells, and confirmation of a new interpretation of the drug supersaturation phenomenon. ( Jacobsen, J; Pedersen, M; Sørensen, AM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tessier, J | 1 |
| Golmohamadi, M | 1 |
| Wilkinson, KJ | 1 |
| Schmitzer, AR | 1 |
| Wei, GX | 1 |
| Bobek, LA | 1 |
| Pedersen, M | 1 |
| Jacobsen, J | 1 |
| Sørensen, AM | 1 |
| Huy, NT | 1 |
| Kamei, K | 1 |
| Kondo, Y | 1 |
| Serada, S | 1 |
| Kanaori, K | 1 |
| Takano, R | 1 |
| Tajima, K | 1 |
| Hara, S | 1 |
| Swamy, KH | 1 |
| Sirsi, M | 1 |
| Rao, GR | 1 |
5 other studies available for miconazole and Extravascular Hemolysis
| Article | Year |
|---|---|
Anti-staphylococcal biofilm activity of miconazoctylium bromide.
Topics: Anti-Bacterial Agents; Biofilms; Hemolysis; Humans; Methicillin-Resistant Staphylococcus aureus; Mic | 2018 |
In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole.
Topics: Antifungal Agents; Candida albicans; Cryptococcus neoformans; Culture Media; Dose-Response Relations | 2004 |
Cyclodextrin inclusion complexes of miconazole and econazole--isolation, toxicity on human cells, and confirmation of a new interpretation of the drug supersaturation phenomenon.
Topics: Antifungal Agents; beta-Cyclodextrins; Cell Culture Techniques; Cell Line; Cell Survival; Cyclodextr | 1999 |
Effect of antifungal azoles on the heme detoxification system of malarial parasite.
Topics: Animals; Antifungal Agents; Antimalarials; Clotrimazole; Electron Spin Resonance Spectroscopy; Eryth | 2002 |
Studies on the mechanism of action of miconazole- II. Interaction of miconazole with mammalian erythrocytes.
Topics: Animals; Cell Membrane Permeability; Chickens; Cricetinae; Erythrocytes; Guinea Pigs; Hemolysis; Imi | 1976 |