miconazole has been researched along with Cystic Fibrosis in 2 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antimicrobial activities of amphotericin B, itraconazole, and miconazole against 101 filamentous fungi from patients with cystic fibrosis were tested by a reproducible microdilution method." | 7.69 | In vitro susceptibilities to amphotericin B, itraconazole, and miconazole of filamentous fungi isolated from patients with cystic fibrosis. ( Benailly, N; Berche, P; Gaillard, JL; Hennequin, C; Lenoir, G; Scheinmann, P; Silly, C; Sorin, M, 1997) |
| "The antimicrobial activities of amphotericin B, itraconazole, and miconazole against 101 filamentous fungi from patients with cystic fibrosis were tested by a reproducible microdilution method." | 3.69 | In vitro susceptibilities to amphotericin B, itraconazole, and miconazole of filamentous fungi isolated from patients with cystic fibrosis. ( Benailly, N; Berche, P; Gaillard, JL; Hennequin, C; Lenoir, G; Scheinmann, P; Silly, C; Sorin, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hennequin, C | 1 |
| Benailly, N | 1 |
| Silly, C | 1 |
| Sorin, M | 1 |
| Scheinmann, P | 1 |
| Lenoir, G | 1 |
| Gaillard, JL | 1 |
| Berche, P | 1 |
| Edwards, JH | 1 |
| Alfaham, M | 1 |
| Fifield, R | 1 |
| Philpot, C | 1 |
| Clement, MJ | 1 |
| Goodchild, MC | 1 |
2 other studies available for miconazole and Cystic Fibrosis
| Article | Year |
|---|---|
In vitro susceptibilities to amphotericin B, itraconazole, and miconazole of filamentous fungi isolated from patients with cystic fibrosis.
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Cystic Fibrosis; Itraconazole; Miconazole; Microbial | 1997 |
Sequential serological responses to Aspergillus fumigatus in patients with cystic fibrosis. Use of antigen 'stretching' to delineate IgG and IgE activity.
Topics: Adolescent; Adult; Antibodies, Fungal; Antigens, Fungal; Aspergillosis; Aspergillus fumigatus; Child | 1990 |