miconazole has been researched along with Corneal Ulcer in 12 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Corneal Ulcer: Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective clinical study was undertaken to evaluate the efficacy of 1% miconazole in 85 cases of smear-positive fungal corneal ulcers." | 5.06 | Management of human keratomycosis with miconazole. ( Gupta, SK; Mohan, M; Panda, A, 1989) |
| "Intravenous miconazole (90 mg daily for 3 weeks) reduced the intensity of experimental fungal keratitis due to Candida albicans in a group of 10 rabbits." | 3.67 | Intravenous miconazole therapy for experimental keratomycosis in rabbits. ( Ishibashi, Y; Matsumoto, Y, 1985) |
| "Miconazole 1% was used for comparative evaluation in another 20 eyes." | 2.66 | Topical silver sulphadiazine--a new drug for ocular keratomycosis. ( Gupta, SK; Kalra, VK; Mohan, M; Sachdev, MS; Vajpayee, RB, 1988) |
| "Miconazole (n = 35) was the most common topical antifungal medication utilised." | 1.30 | Equine ulcerative keratomycosis: visual outcome and ocular survival in 39 cases (1987-1996). ( Andrew, SE; Brooks, DE; Chmielewski, NT; Gelatt, KN; Smith, PJ; Whittaker, CJ, 1998) |
| "Two patients had acquired immunodeficiency syndrome (AIDS), one was human immunodeficiency virus (HIV)-positive, and the fourth refused HIV testing." | 1.29 | Spontaneous ulcerative keratitis in immunocompromised patients. ( Aristimuño, B; Hemady, RK; Nirankari, VS; Rodrigues, MM, 1993) |
| "Diagnosis and treatment of fungal corneal ulcers are discussed briefly." | 1.27 | Keratomycosis caused by Acremonium Recifei, treated with keratoplasty, Miconazole and Ketoconazole. ( Simonsz, HJ, 1983) |
| "Miconazole ointment was well tolerated by the rabbit eye and produced no ocular or systemic toxicity." | 1.27 | Efficacy of miconazole in experimental keratomycosis. ( Gupta, SK, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Voelter-Ratson, K | 1 |
| Monod, M | 1 |
| Braun, U | 1 |
| Spiess, BM | 1 |
| Simonsz, HJ | 1 |
| Reddy, PR | 1 |
| Reddy, PS | 1 |
| Reddy, AR | 1 |
| Saboo, NK | 1 |
| Del Prete, A | 1 |
| Sepe, G | 1 |
| Ferrante, M | 1 |
| Loffredo, C | 1 |
| Masciello, M | 1 |
| Sebastiani, A | 1 |
| Aristimuño, B | 1 |
| Nirankari, VS | 1 |
| Hemady, RK | 1 |
| Rodrigues, MM | 1 |
| Andrew, SE | 1 |
| Brooks, DE | 1 |
| Smith, PJ | 1 |
| Gelatt, KN | 1 |
| Chmielewski, NT | 1 |
| Whittaker, CJ | 1 |
| Sharma, S | 1 |
| Srinivasan, M | 1 |
| George, C | 1 |
| Mohan, M | 2 |
| Panda, A | 1 |
| Gupta, SK | 3 |
| George, J | 1 |
| Thomas, R | 1 |
| Alexander, TA | 1 |
| Kalra, VK | 1 |
| Vajpayee, RB | 1 |
| Sachdev, MS | 1 |
| Ishibashi, Y | 1 |
| Matsumoto, Y | 1 |
2 trials available for miconazole and Corneal Ulcer
| Article | Year |
|---|---|
Management of human keratomycosis with miconazole.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Corneal Ulcer; Eye Infections, Fungal; Female; Fu | 1989 |
Topical silver sulphadiazine--a new drug for ocular keratomycosis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Clinical Trials as Topic; Corneal Ulcer; Double-Bl | 1988 |
10 other studies available for miconazole and Corneal Ulcer
| Article | Year |
|---|---|
Ulcerative fungal keratitis in a Brown Swiss cow.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antifungal Agents; Cattle; Cattle Diseases; | 2013 |
Keratomycosis caused by Acremonium Recifei, treated with keratoplasty, Miconazole and Ketoconazole.
Topics: Acremonium; Administration, Topical; Anti-Bacterial Agents; Corneal Transplantation; Corneal Ulcer; | 1983 |
A comparative evaluation of Nystatin, Amphotericin-B and Miconazole in keratomycosis.
Topics: Amphotericin B; Antifungal Agents; Corneal Ulcer; Humans; Miconazole; Mycoses; Nystatin | 1982 |
Fungal keratitis due to Scopulariopsis brevicaulis in an eye previously suffering from herpetic keratitis.
Topics: Conjunctiva; Corneal Ulcer; Eye Infections, Fungal; Glucocorticoids; Humans; Keratitis, Herpetic; Ma | 1994 |
Spontaneous ulcerative keratitis in immunocompromised patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Amikacin; Amphotericin B; Candid | 1993 |
Equine ulcerative keratomycosis: visual outcome and ocular survival in 39 cases (1987-1996).
Topics: Animals; Anti-Infective Agents, Local; Antifungal Agents; Aspergillus; Corneal Stroma; Corneal Ulcer | 1998 |
Acanthamoeba keratitis in non-contact lens wearers.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Animals; Bacitracin; Clotrimazole; Contact | 1990 |
Keratomycosis treated with miconazole drops.
Topics: Corneal Ulcer; Eye Infections, Fungal; Humans; Miconazole | 1986 |
Efficacy of miconazole in experimental keratomycosis.
Topics: Animals; Aspergillosis; Candidiasis; Corneal Diseases; Corneal Ulcer; Fusarium; Miconazole; Mycoses; | 1986 |
Intravenous miconazole therapy for experimental keratomycosis in rabbits.
Topics: Animals; Candidiasis; Corneal Stroma; Corneal Ulcer; Drug Evaluation, Preclinical; Female; Injection | 1985 |