miconazole has been researched along with Coccidioidomycosis in 36 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Coccidioidomycosis: Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients with endogenous fungal endophthalmitis were treated intravenously with miconazole." | 7.66 | Therapy of endogenous fungal endophthalmitis: miconazole or amphotericin B for coccidioidal and candidal infection. ( Blumenkranz, MS; Stevens, DA, 1980) |
| "Miconazole was injected intravenously in six patients with coccidioidomycosis." | 7.66 | Treatment of coccidioidomycosis with miconazole. ( Goldstein, E; Hoeprich, PD; Lawrence, RM, 1980) |
| "Eight patients with fungal meningitis (5 with the coccidioidal type, 2 with cryptococcal, and 1 with histoplasmosis) were treated with intravenous (IV) and intrathecal (IT) miconazole after previous therapy with amphotericin B proved unsuccessful." | 7.66 | Miconazole therapy for fungal meningitis. ( Campbell, GD; Grendahl, JG; Sung, JP, 1978) |
| "A patient received a previously unreported combination of intravenous miconazole and intrathecal amphotericin B for the treatment of disseminated coccidioidomycosis with central nervous system involvement." | 7.66 | Combined intravenous miconazole and intrathecal amphotericin B for treatment of disseminated coccidioidomycosis. ( Davis, SJ; Donovan, WH, 1979) |
| "Miconazole at dosages up to 30 mg/kg/day was given intravenously to seven patients with complicated courses of disseminated coccidioidomycosis." | 7.66 | Miconazole for treatment of disseminated coccidioidomycosis. Unfavorable experience. ( Linné, SR; Meyer, RD; Ruskin, J; Sattler, FR, 1978) |
| "Twelve patients with fungal meningitis (ten cases were due to Coccidioides immitis, two were from Cryptococcus neoformans) were treated with brief courses of intravenous (IV) miconazole." | 7.65 | Treatment of fungal meningitis with miconazole. ( Deresinski, SC; Galgiani, JN; Levine, HB; Lilly, RB; Stevens, DA, 1977) |
| "Miconazole was administered intravenously in six consecutive patients with, active coccidioidal infection." | 5.26 | Reversible thrombocytosis and anemia due to miconazole therapy. ( Desser, KB; Lilly, RB; Marmion, LC; Stevens, DA, 1976) |
| "Fourteen patients with chronic coccidioidomycosis, many of whom had complicating concurrent diseases and/or had failed to respond to amphotericin therapy, were treated with intravenous miconazole, a synthetic imidazole drug previously shown to be effective in experimental murine coccidioidomycosis." | 4.75 | Miconazole in coccidiodomycosis. II. Therapeutic and pharmacologic studies in man. ( Deresinski, SC; Levine, HB; Stevens, DA, 1976) |
| "The mortality related to coccidioidal meningitis (CM) has been reduced since the introduction of amphotericin B therapy, but children with CM continue to suffer significant morbidity." | 3.67 | Imidazole therapy of coccidioidal meningitis in children. ( Britton, H; Dunn, JH; Shehab, ZM, 1988) |
| "Three patients with endogenous fungal endophthalmitis were treated intravenously with miconazole." | 3.66 | Therapy of endogenous fungal endophthalmitis: miconazole or amphotericin B for coccidioidal and candidal infection. ( Blumenkranz, MS; Stevens, DA, 1980) |
| "Miconazole was injected intravenously in six patients with coccidioidomycosis." | 3.66 | Treatment of coccidioidomycosis with miconazole. ( Goldstein, E; Hoeprich, PD; Lawrence, RM, 1980) |
| "Eight patients with fungal meningitis (5 with the coccidioidal type, 2 with cryptococcal, and 1 with histoplasmosis) were treated with intravenous (IV) and intrathecal (IT) miconazole after previous therapy with amphotericin B proved unsuccessful." | 3.66 | Miconazole therapy for fungal meningitis. ( Campbell, GD; Grendahl, JG; Sung, JP, 1978) |
| "A patient received a previously unreported combination of intravenous miconazole and intrathecal amphotericin B for the treatment of disseminated coccidioidomycosis with central nervous system involvement." | 3.66 | Combined intravenous miconazole and intrathecal amphotericin B for treatment of disseminated coccidioidomycosis. ( Davis, SJ; Donovan, WH, 1979) |
| "Miconazole at dosages up to 30 mg/kg/day was given intravenously to seven patients with complicated courses of disseminated coccidioidomycosis." | 3.66 | Miconazole for treatment of disseminated coccidioidomycosis. Unfavorable experience. ( Linné, SR; Meyer, RD; Ruskin, J; Sattler, FR, 1978) |
| "Ten patients with systemic mycoses, including five with fungal meningitis, were treated with intravenously or intrathecally administered miconazole, or both." | 3.65 | Intravenous and intrathecal miconazole therapy for systemic mycoses. ( Grendahl, JG; Levine, HB; Sung, JP, 1977) |
| "Twelve patients with fungal meningitis (ten cases were due to Coccidioides immitis, two were from Cryptococcus neoformans) were treated with brief courses of intravenous (IV) miconazole." | 3.65 | Treatment of fungal meningitis with miconazole. ( Deresinski, SC; Galgiani, JN; Levine, HB; Lilly, RB; Stevens, DA, 1977) |
| "The therapy of coccidioidomycosis has been an early target, both experimentally and clinically, for study of new members of the azole class of drugs, because of the recognition that coccidioidomycosis is one of the most difficult mycoses to treat, and because our research group and our collaborators have been eager to pioneer new therapies for this problem pathogen." | 2.44 | Azole therapy of clinical and experimental coccidioidomycosis. ( Clemons, KV; Stevens, DA, 2007) |
| "The deep mycoses are increasing in importance both as opportunistic infections and from exposure in geographically defined areas." | 2.37 | Cutaneous and mucosal manifestations of the deep mycotic infections. ( Meyer, RD, 1986) |
| "Four cases in which upper airway obstruction required otolaryngological consultation and intervention are reviewed in detail." | 1.26 | Upper airway obstruction due to coccidioidomycosis. ( Ballantyne, J; Boles, R; Henley-Cohn, J; Weisberger, E, 1979) |
| "Miconazole was administered intravenously in six consecutive patients with, active coccidioidal infection." | 1.26 | Reversible thrombocytosis and anemia due to miconazole therapy. ( Desser, KB; Lilly, RB; Marmion, LC; Stevens, DA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (94.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galgiani, JN | 2 |
| Stevens, DA | 9 |
| Clemons, KV | 1 |
| Sheklakov, ND | 1 |
| Rukavishnikova, VM | 1 |
| Stamm, AM | 1 |
| Dismukes, WE | 1 |
| Blumenkranz, MS | 1 |
| Moskowitz, PS | 1 |
| Sue, JY | 1 |
| Gooding, CA | 1 |
| Bayer, AS | 1 |
| Hoeprich, PD | 2 |
| Lawrence, RM | 1 |
| Goldstein, E | 1 |
| Levine, HB | 6 |
| Drutz, DJ | 1 |
| Catanzaro, A | 2 |
| Basler, RS | 1 |
| Lagomarsino, SL | 1 |
| Henley-Cohn, J | 1 |
| Boles, R | 1 |
| Weisberger, E | 1 |
| Ballantyne, J | 1 |
| Loeb, JM | 1 |
| Livermore, BM | 1 |
| Wofsy, D | 1 |
| Deresinski, SC | 3 |
| Sung, JP | 4 |
| Grendahl, JG | 2 |
| Campbell, GD | 1 |
| Davis, SJ | 1 |
| Donovan, WH | 1 |
| Symoens, J | 1 |
| Amery, W | 1 |
| Danoff, D | 1 |
| Munk, ZM | 1 |
| Case, B | 1 |
| Finlayson, M | 1 |
| Gold, P | 1 |
| Meyer, RD | 2 |
| Sattler, FR | 1 |
| Linné, SR | 1 |
| Ruskin, J | 1 |
| Barr, RJ | 1 |
| Fujita, WH | 1 |
| Graham, JH | 1 |
| Sun, SS | 1 |
| Crutchlow, PF | 1 |
| Lee, JC | 1 |
| Parthemore, JG | 1 |
| Roach, B | 1 |
| Deftos, LJ | 1 |
| Lilly, RB | 2 |
| Stevens, D | 1 |
| Marmion, LC | 1 |
| Desser, KB | 1 |
| Cobb, JM | 1 |
| Gebhardt, AE | 1 |
| Shehab, ZM | 1 |
| Britton, H | 1 |
| Dunn, JH | 1 |
10 reviews available for miconazole and Coccidioidomycosis
| Article | Year |
|---|---|
Coccidioidomycosis: changing perceptions and creating opportunities for its control.
Topics: Administration, Oral; Aminoglycosides; Amphotericin B; Antifungal Agents; Attitude to Health; Coccid | 2007 |
Azole therapy of clinical and experimental coccidioidomycosis.
Topics: Administration, Oral; Animals; Antifungal Agents; Azoles; Coccidioidomycosis; Disease Models, Animal | 2007 |
[Imidazole preparations in mycology].
Topics: Animals; Antifungal Agents; Candidiasis; Clotrimazole; Coccidioidomycosis; Cryptococcosis; Dermatomy | 1984 |
Current therapy of pulmonary and disseminated fungal diseases.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Chromoblastomycosis; C | 1983 |
Miconazole in the treatment of coccidioidomycosis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chronic Disease; Coccidioidomycosis; Female; Human | 1983 |
Miconazole in coccidioidomycosis.
Topics: Animals; Coccidioidomycosis; Humans; Mice; Miconazole | 1977 |
Coccidioidomycosis. Part II.
Topics: Amphotericin B; Arthritis, Infectious; Coccidioidomycosis; Eosinophilia; Erythema; Erythema Multifor | 1978 |
Coccidioidomycosis: clinical review and treatment update.
Topics: Adult; Amphotericin B; Coccidioidomycosis; Female; Humans; Male; Miconazole; Skin; United States | 1979 |
Miconazole in coccidiodomycosis. II. Therapeutic and pharmacologic studies in man.
Topics: Adult; Animals; Coccidioides; Coccidioidomycosis; Humans; Imidazoles; Kinetics; Male; Miconazole; Mi | 1976 |
Cutaneous and mucosal manifestations of the deep mycotic infections.
Topics: Amphotericin B; Aspergillosis; Blastomycosis; Candidiasis; Candidiasis, Cutaneous; Coccidioidomycosi | 1986 |
1 trial available for miconazole and Coccidioidomycosis
| Article | Year |
|---|---|
New antifungal drugs in the therapy of systemic mycoses.
Topics: Adult; Amphotericin B; Animals; Cats; Clinical Trials as Topic; Coccidioidomycosis; Dermatomycoses; | 1978 |
25 other studies available for miconazole and Coccidioidomycosis
| Article | Year |
|---|---|
Therapy of endogenous fungal endophthalmitis: miconazole or amphotericin B for coccidioidal and candidal infection.
Topics: Adult; Amphotericin B; Candidiasis; Coccidioidomycosis; Endophthalmitis; Female; Fluorescein Angiogr | 1980 |
Tracheal coccidioidomycosis causing upper airway obstruction in children.
Topics: Amphotericin B; Child; Child, Preschool; Coccidioidomycosis; Granuloma; Humans; Male; Miconazole; Ra | 1982 |
Fungal pneumonias: pulmonary coccidioidal syndromes (Part 2). Miliary, nodular, and cavitary pulmonary coccidioidomycosis; chemotherapeutic and surgical considerations.
Topics: Amphotericin B; Coccidioidomycosis; Humans; Lung; Lung Diseases, Fungal; Miconazole; Nausea; Pneumon | 1981 |
Treatment of coccidioidomycosis with miconazole.
Topics: Adult; Amphotericin B; Coccidioidomycosis; Drug Evaluation; Drug Therapy, Combination; Female; Human | 1980 |
Miconazole against tropical mycoses.
Topics: Administration, Oral; Coccidioidomycosis; Drug Evaluation; Humans; Imidazoles; Miconazole; Paracocci | 1979 |
[Miconazole in the treatment of systemic mycotic infections].
Topics: Coccidioidomycosis; Humans; Imidazoles; Miconazole | 1979 |
Upper airway obstruction due to coccidioidomycosis.
Topics: Aged; Airway Obstruction; Amphotericin B; Coccidioidomycosis; Female; Humans; Male; Miconazole; Midd | 1979 |
Coccidioidomycosis of the thyroid.
Topics: Adult; Amphotericin B; Biopsy, Needle; Coccidioides; Coccidioidomycosis; Female; Humans; Male; Micon | 1979 |
Bone and joint coccidioidomycosis treated with miconazole.
Topics: Adolescent; Adult; Aged; Arthritis; Bone Diseases; Child; Chronic Disease; Coccidioidomycosis; Femal | 1979 |
Intravenous and intrathecal miconazole therapy for systemic mycoses.
Topics: Aged; Candidiasis; Coccidioidomycosis; Cryptococcosis; Humans; Imidazoles; Infusions, Parenteral; In | 1977 |
Miconazole therapy for fungal meningitis.
Topics: Adult; Aged; Arachnoiditis; Cerebral Hemorrhage; Cisterna Magna; Coccidioidomycosis; Cryptococcosis; | 1978 |
Combined intravenous miconazole and intrathecal amphotericin B for treatment of disseminated coccidioidomycosis.
Topics: Adult; Amphotericin B; Chronic Disease; Coccidioidomycosis; Drug Therapy, Combination; Humans; Imida | 1979 |
Treatment of systemic mycoses with miconazole: a review.
Topics: Administration, Oral; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Cryptococcosis; | 1977 |
Disseminated coccidioidomycosis: clinical, immunologic and therapeutic aspects.
Topics: Adult; Amphotericin B; Coccidioidomycosis; Dermatomycoses; Humans; Immunity, Cellular; Male; Meningi | 1978 |
Miconazole for treatment of disseminated coccidioidomycosis. Unfavorable experience.
Topics: Adult; Amphotericin B; Coccidioidomycosis; Drug Evaluation; Humans; Imidazoles; Infusions, Parentera | 1978 |
Eruptive xanthomas associated with intravenous miconazole therapy.
Topics: Aged; Coccidioidomycosis; Humans; Imidazoles; Male; Miconazole; Xanthomatosis | 1978 |
Coccidioidomycosis of the prostate gland and its therapy.
Topics: Amphotericin B; Biopsy; Coccidioidomycosis; Humans; Immunotherapy; Male; Miconazole; Middle Aged; Pr | 1979 |
Hypercalcemia in disseminated coccidioidomycosis.
Topics: Adolescent; Adult; Amphotericin B; Biopsy; Bone Marrow; Calcitonin; Calcium; Coccidioides; Coccidioi | 1977 |
Treatment of fungal meningitis with miconazole.
Topics: Adolescent; Adult; Aged; Coccidioidomycosis; Cryptococcosis; Female; Humans; Imidazoles; Infusions, | 1977 |
Miconazole in the treatment of systemic fungal infections.
Topics: Adolescent; Adult; Aged; Child; Coccidioidomycosis; Drug Resistance, Microbial; Humans; Imidazoles; | 1977 |
Reversible thrombocytosis and anemia due to miconazole therapy.
Topics: Adolescent; Adult; Aged; Anemia; Coccidioidomycosis; Female; Humans; Imidazoles; Infusions, Parenter | 1976 |
R34000, a dioxolane imidazole in the therapy for experimental coccidioidomycosis. Comparison with miconazole and econazole.
Topics: Administration, Oral; Animals; Coccidioides; Coccidioidomycosis; Dioxolanes; Dioxoles; Disease Model | 1976 |
Miconazole in coccidioidomycosis. I. Assays of activity in mice and in vitro.
Topics: Animals; Coccidioides; Coccidioidomycosis; Female; Imidazoles; Mice; Miconazole; Species Specificity | 1975 |
Treatment of disseminated coccidioidomycosis with miconazole.
Topics: Amphotericin B; Antifungal Agents; Coccidioidomycosis; Drug Administration Schedule; Drug Resistance | 1976 |
Imidazole therapy of coccidioidal meningitis in children.
Topics: Administration, Oral; Amphotericin B; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Coccidioi | 1988 |