Page last updated: 2024-10-31

miconazole and Cancer of Head

miconazole has been researched along with Cancer of Head in 3 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Research Excerpts

ExcerptRelevanceReference
"Two hundred eighty-two patients with head and neck cancer received a 14-day treatment of either single-dose MBT or MOG administered in 4 divided doses."2.73Comparison of the efficacy and safety of miconazole 50-mg mucoadhesive buccal tablets with miconazole 500-mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in patients ( Allavena, C; Attali, P; Bastit, L; Bensadoun, RJ; Calais, G; Céruse, P; Daoud, J; El Gueddari, B; Gourmet, R; Rosikon, A, 2008)
"Participants were patients with head and neck cancer receiving RT ≥ 60 Gy."1.72Effects of a miconazole oral patch on preventing development of oral candidiasis in patients with head and neck cancer undergoing radiotherapy: results of a preliminary study quantifying the prevalence of Candida albicans in saliva. ( Akashi, M; Funahara, M; Funahara, R; Hasegawa, T; Soutome, S; Tsuda, S; Umeda, M, 2022)
" The miconazole hydroxypropyl-beta-cyclodextrin product and genuine cyclodextrin inclusion complexes of miconazole, econazole and clotrimazole were toxic on a human TR146 buccal cell culture model."1.30Cyclodextrin inclusion complexes of antimycotics intended to act in the oral cavity--drug supersaturation, toxicity on TR146 cells and release from a delivery system. ( Bjerregaard, S; Jacobsen, J; Pedersen, M, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Funahara, R1
Soutome, S1
Funahara, M1
Tsuda, S1
Hasegawa, T1
Umeda, M1
Akashi, M1
Bensadoun, RJ1
Daoud, J1
El Gueddari, B1
Bastit, L1
Gourmet, R1
Rosikon, A1
Allavena, C1
Céruse, P1
Calais, G1
Attali, P1
Jacobsen, J1
Bjerregaard, S1
Pedersen, M1

Trials

1 trial available for miconazole and Cancer of Head

ArticleYear
Comparison of the efficacy and safety of miconazole 50-mg mucoadhesive buccal tablets with miconazole 500-mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in patients
    Cancer, 2008, Jan-01, Volume: 112, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Candidiasis, Oral; Female; Gels; Head

2008

Other Studies

2 other studies available for miconazole and Cancer of Head

ArticleYear
Effects of a miconazole oral patch on preventing development of oral candidiasis in patients with head and neck cancer undergoing radiotherapy: results of a preliminary study quantifying the prevalence of Candida albicans in saliva.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:1

    Topics: Candida albicans; Candidiasis, Oral; Head and Neck Neoplasms; Humans; Miconazole; Prevalence; Saliva

2022
Cyclodextrin inclusion complexes of antimycotics intended to act in the oral cavity--drug supersaturation, toxicity on TR146 cells and release from a delivery system.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1999, Volume: 48, Issue:3

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Antifungal Agents; beta-Cyclodextrins; Candida albicans; Carcinom

1999