miconazole has been researched along with Breast Neoplasms in 8 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of the antifungal drug miconazole on Ca²⁺ signaling in human breast cancer cells is unknown." | 7.81 | Effect of Miconazole on [Ca²⁺]i and Cytotoxicity in ZR-75-1 Human Breast Cancer Cells. ( Chang, HT; Chen, FA; Chou, CT; Jan, CR; Kuo, CC; Kuo, DH; Liang, WZ; Roan, CJ; Shieh, P, 2015) |
| "This study was undertaken to investigate whether miconazole (MCZ), an antifungal agent, inhibits aromatase activity in human breast cancer tissue preparations (n = 6)." | 7.67 | In vivo and in vitro effects of the antifungal agent miconazole on estrogen biosynthesis in human breast cancer. ( Fukuoka, M; Okada, H; Yamamoto, T; Yasumura, T, 1989) |
| "The effect of the antifungal drug miconazole on Ca²⁺ signaling in human breast cancer cells is unknown." | 3.81 | Effect of Miconazole on [Ca²⁺]i and Cytotoxicity in ZR-75-1 Human Breast Cancer Cells. ( Chang, HT; Chen, FA; Chou, CT; Jan, CR; Kuo, CC; Kuo, DH; Liang, WZ; Roan, CJ; Shieh, P, 2015) |
| "This study was undertaken to investigate whether miconazole (MCZ), an antifungal agent, inhibits aromatase activity in human breast cancer tissue preparations (n = 6)." | 3.67 | In vivo and in vitro effects of the antifungal agent miconazole on estrogen biosynthesis in human breast cancer. ( Fukuoka, M; Okada, H; Yamamoto, T; Yasumura, T, 1989) |
| "In addition, progestins, which increase breast cancer incidence, expand the CK5(+) subpopulation in ER(+)PR(+) breast cancer cell lines." | 1.38 | A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer. ( Axlund, SD; Kabos, P; LaBarbera, DV; Reid, BG; Sartorius, CA; Schaack, J; Yoo, BH, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muftuoglu, Y | 1 |
| Mustata, G | 1 |
| Al-Trawneh, SA | 1 |
| El-Abadelah, MM | 1 |
| Zahra, JA | 1 |
| Al-Taweel, SA | 1 |
| Zani, F | 1 |
| Incerti, M | 1 |
| Cavazzoni, A | 1 |
| Vicini, P | 1 |
| Chengzhu, WU | 1 |
| Gao, M | 1 |
| Shen, L | 1 |
| Bohan, LI | 1 |
| Bai, X | 1 |
| Gui, J | 1 |
| Hongmei, LI | 1 |
| Huo, Q | 1 |
| Tao, MA | 1 |
| Roan, CJ | 1 |
| Chou, CT | 1 |
| Liang, WZ | 1 |
| Chang, HT | 1 |
| Kuo, DH | 1 |
| Kuo, CC | 1 |
| Chen, FA | 1 |
| Shieh, P | 1 |
| Jan, CR | 1 |
| Landowski, CP | 1 |
| Bolanz, KA | 1 |
| Suzuki, Y | 1 |
| Hediger, MA | 1 |
| Yoo, BH | 1 |
| Axlund, SD | 1 |
| Kabos, P | 1 |
| Reid, BG | 1 |
| Schaack, J | 1 |
| Sartorius, CA | 1 |
| LaBarbera, DV | 1 |
| Jones, AL | 1 |
| Dowsett, MJ | 1 |
| Powles, TJ | 1 |
| Gallagher, CJ | 1 |
| Coombes, RC | 1 |
| Yamamoto, T | 1 |
| Fukuoka, M | 1 |
| Yasumura, T | 1 |
| Okada, H | 1 |
8 other studies available for miconazole and Breast Neoplasms
| Article | Year |
|---|---|
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Si | 2010 |
Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell | 2011 |
Miconazole triggers various forms of cell death in human breast cancer MDA-MB-231 cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survi | 2019 |
Effect of Miconazole on [Ca²⁺]i and Cytotoxicity in ZR-75-1 Human Breast Cancer Cells.
Topics: Breast Neoplasms; Calcium; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Female | 2015 |
Chemical inhibitors of the calcium entry channel TRPV6.
Topics: Animals; Breast Neoplasms; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Proliferation; | 2011 |
A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer.
Topics: Acitretin; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; | 2012 |
Treatment of advanced breast cancer with miconazole: a potential inhibitor of peripheral oestrogen synthesis.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Humans; M | 1991 |
In vivo and in vitro effects of the antifungal agent miconazole on estrogen biosynthesis in human breast cancer.
Topics: Adenocarcinoma, Papillary; Adult; Aged; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens | 1989 |