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miconazole and Brain Abscess

miconazole has been researched along with Brain Abscess in 7 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Brain Abscess: A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)

Research Excerpts

ExcerptRelevanceReference
" Progressive increases in miconazole dosage during the treatment periods were required to produce serum levels above the minimum inhibitory concentrations of the fungal isolates."5.28Pseudallescheria boydii brain abscess: association with near-drowning and efficacy of high-dose, prolonged miconazole therapy in patients with multiple abscesses. ( Borkowski, WJ; Clark, RB; Connolly, TL; Dworzack, DL; Dykstra, M; Horowitz, EA; Hostetler, MK; McKinney, DL; Pugsley, MP; Smith, DL, 1989)
"The previous cases of Pseudallescheria brain abscess are reviewed, and the histopathologic features of Pseudallescheria which permit its differentiation from Aspergillus and other fungi are discussed."2.38Cerebral Pseudallescheria boydii infection: unique occurrence of fungus ball formation in the brain. ( Amenta, PS; Finkelstein, SD; Schwartz, DA, 1989)
"Miconazole was administered intravenously and intraventricularly for 1 month."1.28[Multiple aspergillus brain abscess complicated with systemic lupus erythematosus--case report]. ( Akabane, M; Ebina, K; Hirano, T; Ohi, H; Sugawara, A; Yoshimura, S, 1991)
" Progressive increases in miconazole dosage during the treatment periods were required to produce serum levels above the minimum inhibitory concentrations of the fungal isolates."1.28Pseudallescheria boydii brain abscess: association with near-drowning and efficacy of high-dose, prolonged miconazole therapy in patients with multiple abscesses. ( Borkowski, WJ; Clark, RB; Connolly, TL; Dworzack, DL; Dykstra, M; Horowitz, EA; Hostetler, MK; McKinney, DL; Pugsley, MP; Smith, DL, 1989)
"An adult patient survived a brain abscess with Pseudallescheria boydii."1.27Pseudallescheria boydii brain abscess. Complication of an intravenous catheter. ( Eugenio, N; Kim, J; McClendon, J; Pérez, RE; Smith, M, 1988)
"Miconazole appeared to cause resolution of the cerebral abscess."1.26Disseminated Curvularia lunata infection in a football player. ( Colfer, H; Gatmaitan, B; Rohwedder, JJ; Simmons, JL, 1979)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, RL1
Carroll, TF1
Harvey, JT1
Myers, MG1
Fry, VG1
Young, CN1
Rohwedder, JJ1
Simmons, JL1
Colfer, H1
Gatmaitan, B1
Sugawara, A1
Ebina, K1
Hirano, T1
Ohi, H1
Yoshimura, S1
Akabane, M1
Schwartz, DA1
Amenta, PS1
Finkelstein, SD1
Dworzack, DL1
Clark, RB1
Borkowski, WJ1
Smith, DL1
Dykstra, M1
Pugsley, MP1
Horowitz, EA1
Connolly, TL1
McKinney, DL1
Hostetler, MK1
Pérez, RE1
Smith, M1
McClendon, J1
Kim, J1
Eugenio, N1

Reviews

1 review available for miconazole and Brain Abscess

ArticleYear
Cerebral Pseudallescheria boydii infection: unique occurrence of fungus ball formation in the brain.
    Clinical neurology and neurosurgery, 1989, Volume: 91, Issue:1

    Topics: Adult; Brain Abscess; Humans; Ketoconazole; Male; Miconazole; Mycetoma; Pseudallescheria

1989

Other Studies

6 other studies available for miconazole and Brain Abscess

ArticleYear
Petriellidium (Allescheria) boydii orbital and brain abscess treated with intravenous miconazole.
    American journal of ophthalmology, 1984, Volume: 97, Issue:6

    Topics: Ascomycota; Brain Abscess; Child, Preschool; Frontal Lobe; Humans; Injections, Intravenous; Male; Mi

1984
A rare fungal brain abscess in an uncompromised host.
    Surgical neurology, 1981, Volume: 15, Issue:6

    Topics: Aged; Ascomycota; Brain Abscess; Drainage; Female; Humans; Imidazoles; Miconazole; Mycoses; Parietal

1981
Disseminated Curvularia lunata infection in a football player.
    Archives of internal medicine, 1979, Volume: 139, Issue:8

    Topics: Abscess; Adult; Amphotericin B; Athletic Injuries; Brain Abscess; Drainage; Football; Humans; Leg Ul

1979
[Multiple aspergillus brain abscess complicated with systemic lupus erythematosus--case report].
    Neurologia medico-chirurgica, 1991, Volume: 31, Issue:13

    Topics: Adolescent; Aspergillosis; Brain Abscess; Catheters, Indwelling; Combined Modality Therapy; Cranioto

1991
Pseudallescheria boydii brain abscess: association with near-drowning and efficacy of high-dose, prolonged miconazole therapy in patients with multiple abscesses.
    Medicine, 1989, Volume: 68, Issue:4

    Topics: Adult; Brain Abscess; Child, Preschool; Drowning; Female; Humans; Male; Miconazole; Middle Aged; Myc

1989
Pseudallescheria boydii brain abscess. Complication of an intravenous catheter.
    The American journal of medicine, 1988, Volume: 84, Issue:2

    Topics: Adult; Ascomycota; Brain Abscess; Catheterization, Central Venous; Female; Humans; Miconazole; Mycos

1988