miconazole has been researched along with Bleeding in 9 studies
Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Increases in the INR and cases of bleeding have been reported during concomitant use of miconazole oral gel or mucoadhesive buccal tablets and a vitamin K antagonist (fluindione or warfarin)." | 7.81 | Miconazole and oral anticoagulants: bleeding. ( , 2015) |
| "Increases in the INR and cases of bleeding have been reported during concomitant use of miconazole oral gel or mucoadhesive buccal tablets and a vitamin K antagonist (fluindione or warfarin)." | 3.81 | Miconazole and oral anticoagulants: bleeding. ( , 2015) |
| "Miconazole oral gel and topically applied nystatin solution have equally strong effects on warfarin activity and can provoke major bleeding." | 3.78 | Miconazole and nystatin used as topical antifungal drugs interact equally strongly with warfarin. ( Kovac, M; Kovac, Z; Mitic, G, 2012) |
| "Miconazole is a strong inhibitor of CYP2C9, one of the main enzymes involved in the metabolism of warfarin." | 2.47 | Warfarin and miconazole oral gel interactions: analysis and therapy recommendations based on clinical data and a pharmacokinetic model. ( Miki, A; Ohtani, H; Sawada, Y, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Pauw, A | 1 |
| De Backer, T | 1 |
| Miki, A | 1 |
| Ohtani, H | 1 |
| Sawada, Y | 1 |
| Kovac, M | 1 |
| Mitic, G | 1 |
| Kovac, Z | 1 |
| Paul, R | 1 |
| Watson, PG | 1 |
| Lochan, RG | 1 |
| Redding, VJ | 1 |
| Evans, J | 1 |
| Orme, DS | 1 |
| Sedgwick, ML | 1 |
| Youngs, GR | 1 |
| Silingardi, M | 1 |
| Ghirarduzzi, A | 1 |
| Tincani, E | 1 |
| Iorio, A | 1 |
| Iori, I | 1 |
| Murty, M | 1 |
2 reviews available for miconazole and Bleeding
| Article | Year |
|---|---|
Warfarin and miconazole oral gel interactions: analysis and therapy recommendations based on clinical data and a pharmacokinetic model.
Topics: Administration, Oral; Anticoagulants; Antifungal Agents; Biological Availability; Drug Interactions; | 2011 |
Miconazole oral gel potentiates warfarin anticoagulant activity.
Topics: Administration, Oral; Aged; Anticoagulants; Antifungal Agents; Drug Synergism; Female; Gels; Hemorrh | 2000 |
7 other studies available for miconazole and Bleeding
| Article | Year |
|---|---|
Miconazole buccal gel and risk for systemic bleeding: how certain topical formula can interfere with anticoagulants.
Topics: Administration, Oral; Administration, Topical; Aged; Aged, 80 and over; Anticoagulants; Antifungal A | 2015 |
Miconazole and oral anticoagulants: bleeding.
Topics: Administration, Buccal; Anticoagulants; Antifungal Agents; Blood Coagulation; Drug Interactions; Hem | 2015 |
Miconazole and nystatin used as topical antifungal drugs interact equally strongly with warfarin.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anticoagulants; Antifungal Agents; Dose-Respon | 2012 |
[Bleeding problems of a patient with hypothyroidism].
Topics: Aged; Anemia; Anticoagulants; Antifungal Agents; Atrial Fibrillation; Drug Interactions; Ecchymosis; | 2002 |
Drug interactions with coumarin derivative anticoagulants.
Topics: Drug Interactions; Female; Hemorrhage; Humans; Imidazoles; Male; Miconazole; Middle Aged; Warfarin | 1982 |
Treating oral candidiasis: potentially fatal.
Topics: Administration, Oral; Administration, Topical; Aged; Anticoagulants; Antifungal Agents; Candidiasis, | 1997 |
Miconazole-warfarin interaction: increased INR.
Topics: Anticoagulants; Antifungal Agents; Blood Coagulation; Drug Interactions; Hemorrhage; Humans; Interna | 2001 |