Page last updated: 2024-10-31

miconazole and Bacterial Disease

miconazole has been researched along with Bacterial Disease in 17 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Research Excerpts

ExcerptRelevanceReference
"Patients treated with cytotoxic therapy expected to produce neutropenia lasting two or more weeks were randomly assigned in a double-blind study to receive intravenous miconazole or placebo concomitant with empiric antibiotics to test whether miconazole can prevent fungal sepsis."9.06Prevention of fungal sepsis in patients with prolonged neutropenia: a randomized, double-blind, placebo-controlled trial of intravenous miconazole. ( Braine, HG; Merz, WG; Saral, R; Vaughan, WP; Wingard, JR, 1987)
"Patients treated with cytotoxic therapy expected to produce neutropenia lasting two or more weeks were randomly assigned in a double-blind study to receive intravenous miconazole or placebo concomitant with empiric antibiotics to test whether miconazole can prevent fungal sepsis."5.06Prevention of fungal sepsis in patients with prolonged neutropenia: a randomized, double-blind, placebo-controlled trial of intravenous miconazole. ( Braine, HG; Merz, WG; Saral, R; Vaughan, WP; Wingard, JR, 1987)
"Hospital-acquired and community-acquired bacterial infections have already put a heavy burden on the global health system."2.61Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. ( Zhang, B, 2019)
"The different forms of hospital infections have been reviewed and classified as 1."1.26[Infections in children with malignant disease (author's transl)]. ( Krepler, P, 1979)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's5 (29.41)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Hatnapure, GD1
Keche, AP1
Rodge, AH1
Birajdar, SS1
Tale, RH1
Kamble, VM1
Ratnakar Reddy, K1
Poornachandra, Y2
Jitender Dev, G1
Mallareddy, G1
Nanubolu, JB1
Kumar, CG2
Narsaiah, B1
Venepally, V1
Prasad, RBN1
Jala, RCR1
Zhang, B1
Ngoc Toan, V1
Dinh Thanh, N1
Minh Tri, N1
Thi Thu Huong, N1
Schierholz, JM1
Nagelschmidt, K1
Nagelschmidt, M1
Lefering, R2
Yücel, N2
Beuth, J2
Maegele, M1
Max, M1
Rossaint, R1
Koch, A1
Schwarz, R1
Korenkov, M1
Bach, A1
Schierholz, J1
Pulverer, G1
Neugebauer, EA1
Maksymiuk, AW1
Thongprasert, S1
Hopfer, R1
Luna, M1
Fainstein, V1
Bodey, GP2
Rosenbaum, B1
Valdivieso, M1
Bolivar, R1
Van Cutsem, J1
Van Gerven, F1
De Keyser, H1
White, I1
Blatchford, N1
Nisselle, P1
Zazgornik, J1
Schmidt, P1
Kopsa, H1
Pils, P1
Balcke, P1
Krepler, P1
Landers, DV1
Wingard, JR1
Vaughan, WP1
Braine, HG1
Merz, WG1
Saral, R1
Blanc, B1

Reviews

2 reviews available for miconazole and Bacterial Disease

ArticleYear
Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids.
    European journal of medicinal chemistry, 2019, Apr-15, Volume: 168

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Dose-Response Relationship, Drug; Humans; Mic

2019
The treatment of vaginitis: Trichomonas, yeast, and bacterial vaginosis.
    Clinical obstetrics and gynecology, 1988, Volume: 31, Issue:2

    Topics: Antifungal Agents; Bacterial Infections; Candidiasis, Vulvovaginal; Clotrimazole; Drug Administratio

1988

Trials

3 trials available for miconazole and Bacterial Disease

ArticleYear
Antimicrobial central venous catheters in oncology: efficacy of a rifampicin-miconazole-releasing catheter.
    Anticancer research, 2010, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antitubercular; Antifungal Agents; Bacteria

2010
Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical trial.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; Catheteriza

2004
Prevention of fungal sepsis in patients with prolonged neutropenia: a randomized, double-blind, placebo-controlled trial of intravenous miconazole.
    The American journal of medicine, 1987, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Amphotericin B; Bacterial Infections; Bone Marrow Transpla

1987

Other Studies

12 other studies available for miconazole and Bacterial Disease

ArticleYear
Synthesis and biological evaluation of novel piperazine derivatives of flavone as potent anti-inflammatory and antimicrobial agent.
    Bioorganic & medicinal chemistry letters, 2012, Oct-15, Volume: 22, Issue:20

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Bacteria; Bacterial Infections; Flavones; Fungi; Hu

2012
Synthesis of novel amide functionalized 2H-chromene derivatives by Ritter amidation of primary alcohol using HBF4·OEt2 as a mild and versatile reagent and evaluation of their antimicrobial and anti-biofilm activities.
    Bioorganic & medicinal chemistry letters, 2015, Aug-01, Volume: 25, Issue:15

    Topics: Amides; Anti-Infective Agents; Bacteria; Bacterial Infections; Benzopyrans; Biofilms; Borates; Boric

2015
Synthesis of novel ethyl 1-ethyl-6-fluoro-7-(fatty amido)-1,4-dihydro-4-oxoquinoline-3-carboxylate derivatives and their biological evaluation.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Bac

2016
Synthesis and biological screening of thiosemicarbazones of substituted 3-acetylcoumarins having d-glucose moiety.
    Bioorganic & medicinal chemistry letters, 2020, 12-15, Volume: 30, Issue:24

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Bacterial Infections; Cou

2020
Systemic candidiasis in cancer patients.
    The American journal of medicine, 1984, Oct-30, Volume: 77, Issue:4D

    Topics: Acute Disease; Amphotericin B; Bacterial Infections; Bacteriological Techniques; Candida; Candidiasi

1984
Effect of systemic antimicrobial prophylaxis on microbial flora.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Carcinoma

1982
Sensitivity of Moraxella bovis in vitro to miconazole nitrate.
    The Veterinary record, 1983, Jan-08, Volume: 112, Issue:2

    Topics: Animals; Bacterial Infections; Cattle; Cattle Diseases; Drug Resistance, Microbial; Imidazoles; Kera

1983
The treatment of secondary bacterial infections in atopic eczema with miconazole plus hydrocortisone.
    The British journal of clinical practice, 1983, Volume: 37, Issue:6

    Topics: Administration, Topical; Anti-Inflammatory Agents; Bacterial Infections; Dermatitis, Atopic; Drug Co

1983
The management of vaginal discharges.
    Australian family physician, 1980, Volume: 9, Issue:12

    Topics: Bacterial Infections; Candidiasis, Vulvovaginal; Female; Humans; Metronidazole; Miconazole; Nystatin

1980
[Mixed infection after renal transplantation (author's transl)].
    Wiener klinische Wochenschrift, 1979, Aug-10, Volume: 91, Issue:15

    Topics: Bacterial Infections; Female; Gentamicins; Humans; Immunosuppression Therapy; Kidney Transplantation

1979
[Infections in children with malignant disease (author's transl)].
    Wiener klinische Wochenschrift, 1979, Nov-09, Volume: 91, Issue:21

    Topics: Amphotericin B; Antineoplastic Agents; Bacterial Infections; Blood Transfusion; Child; Communicable

1979
[Effectiveness of 400 mg miconazole pellets in various types of vaginitis].
    Revue francaise de gynecologie et d'obstetrique, 1985, Volume: 80, Issue:1

    Topics: Administration, Topical; Adult; Bacterial Infections; Candidiasis, Vulvovaginal; Capsules; Female; H

1985