Page last updated: 2024-10-31

miconazole and Acute Confusional Senile Dementia

miconazole has been researched along with Acute Confusional Senile Dementia in 3 studies

Miconazole: An imidazole antifungal agent that is used topically and by intravenous infusion.
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group.
miconazole : A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes.

Research Excerpts

ExcerptRelevanceReference
"Miconazole treatment increased oligodendrocyte maturation and myelin sheath thickness without reducing Aβ plaque deposition, reactive gliosis, and inflammatory factor levels in the mPFC."5.72Miconazole Promotes Cooperative Ability of a Mouse Model of Alzheimer Disease. ( Chen, S; Chen, Y; Ding, S; Feng, W; Marshall, C; Pang, Y; Sheng, C; Shi, J; Wang, Z; Xiao, M; Zhang, Y, 2022)
"Miconazole treatment increased oligodendrocyte maturation and myelin sheath thickness without reducing Aβ plaque deposition, reactive gliosis, and inflammatory factor levels in the mPFC."1.72Miconazole Promotes Cooperative Ability of a Mouse Model of Alzheimer Disease. ( Chen, S; Chen, Y; Ding, S; Feng, W; Marshall, C; Pang, Y; Sheng, C; Shi, J; Wang, Z; Xiao, M; Zhang, Y, 2022)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Lu, X2
He, SY1
Li, Q1
Yang, H1
Jiang, X1
Lin, H1
Chen, Y3
Qu, W1
Feng, F1
Bian, Y1
Zhou, Y2
Sun, H2
Du, C1
Liu, Y1
Wang, Y1
Hong, KH1
Wang, Z1
Zhang, Y1
Feng, W1
Pang, Y1
Chen, S1
Ding, S1
Sheng, C1
Marshall, C1
Shi, J1
Xiao, M1

Other Studies

3 other studies available for miconazole and Acute Confusional Senile Dementia

ArticleYear
Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Dose-Response Relationship,

2018
Novel BuChE-IDO1 inhibitors from sertaconazole: Virtual screening, chemical optimization and molecular modeling studies.
    Bioorganic & medicinal chemistry letters, 2021, 02-15, Volume: 34

    Topics: Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Dru

2021
Miconazole Promotes Cooperative Ability of a Mouse Model of Alzheimer Disease.
    The international journal of neuropsychopharmacology, 2022, 11-17, Volume: 25, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, A

2022